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The map label for this gene is dat [H]

Identifier: 148828127

GI number: 148828127

Start: 1540018

End: 1541382

Strand: Reverse

Name: dat [H]

Synonym: CGSHiGG_08315

Alternate gene names: 148828127

Gene position: 1541382-1540018 (Counterclockwise)

Preceding gene: 148828128

Following gene: 148828126

Centisome position: 81.68

GC content: 43.59

Gene sequence:

>1365_bases
ATGACAATGATTACCCCTGTACAAGCAATTCTTGCTTCAAACCAACATTTTTTAGATCGCCAAGATGTAATGGAATCCAA
CGTACGTAGTTATCCTCGCAAATTACCTTTTGCCTATGCAAAAGCACAAGGCTGTTGGGTTACTGATGTTGAAGGTAATG
AATACCTAGACTTTTTAGCAGGCGCAGGAACCCTTGCATTAGGACATAATCATCCTATATTAATGCAAGCCATTAAAGAC
GTATTAGATAGCGGATTGCCGTTACACACTTTAGATTTAACCACTCCACTTAAAGATGCGTTTAGTGAAGAATTATTGTC
ATTCTTCCCGAAAGATAAATATATCTTACAATTCACAGGCCCTTCTGGTGCAGATGCAAATGAAGCAGCCATCAAATTAG
CCAAAACTTACACAGGGCGTGGCAATATCATTGCTTTCTCTGGCGGTTTTCACGGTATGACCCAAGGGGCATTAGCCTTA
ACGGGTAATCTTGGTGCAAAAAATGCCGTTGAAAATTTAATGCCTGGCGTACAATTTATGCCATATCCACACGAATACCG
CTGCCCATTTGGCATTGGTGGCGAAGCGGGCGCGAAAGCAGTTGAACATTACTTTGAGAACTTCATCGAAGATGTAGAAA
GTGGCGTAGTAAAACCAGCTGCAGTAATTTTAGAAGCAATCCAAGGAGAAGGCGGCGTTGTTCCAGCACCAATAAGCTTC
TTACAAAAAGTACGTGAAGTAACCCAAAAACACGGCATTTTAATGATCGTCGATGAAGTGCAAGCTGGTTTCTGCCGTTC
TGGAAGAATGTTCGCCTTTGAACACGCAGGCATTGAGCCTGATATTATTGTGATGTCAAAAGCAGTTGGTGGCAGCTTAC
CATTAGCTGTATTAGCTATTCGTAAAGAATTTGATGCTTGGCAACCTGCAGGACATACAGGTACATTTCGTGGCAATCAA
TTAGCGATGGCGACAGGCTACGCTTCACTTAAAATTATGCGTGATGAAAACCTCGCACAAAATGCCCAAGAGCGTGGTGA
ATACTTAACCAACGCATTACGCGAATTAAGCAAAGAATATCCGTGCATCGACAACGTACGTGGTCGTGGCTTAATGATGG
GGATCGATATTGTAGACGAACGCCAATCGAAAGATGCGACAGGGGCTTACCCGCGCGATTGTGAATTAGCGGCAGCAATC
CAAAAAGCTTGCTTCAAAAACAAACTCTTGCTCGAACGTGGCGGACGCGGTGGCAACGTGGTTCGAGTACTTTGTGCGGT
GAACATCAACCAAGTCGAGTGCGAAGAGTTCATCAAACGCTTCAAACAATCTGTTGTAGACGCATTGAAAGTGGTGCGTA
GTTAA

Upstream 100 bases:

>100_bases
AGCGAGTCAAATGCCCTATGTGTCTGTTTTATAAACAGTAAATTTATCGCAAGGCACCCGACTTATTTTTTTCACCTCTT
TTAGAAGGTTTTAATCAAAA

Downstream 100 bases:

>100_bases
TTAAAAGCGGTCTGATTTTGCAAATGTTTTGCGAATTTTGACCGCTTGTAAATTCAAAATGGTAGGGAAATCCCACCTTT
TTTCTACTCAACTGTATAAA

Product: diaminobutyrate--2-oxoglutarate aminotransferase

Products: NA

Alternate protein names: Diaminobutyrate transaminase; L-2,4-diaminobutyrate:2-ketoglutarate 4-aminotransferase; DABA aminotransferase; DABA-AT; L-diaminobutyric acid transaminase [H]

Number of amino acids: Translated: 454; Mature: 453

Protein sequence:

>454_residues
MTMITPVQAILASNQHFLDRQDVMESNVRSYPRKLPFAYAKAQGCWVTDVEGNEYLDFLAGAGTLALGHNHPILMQAIKD
VLDSGLPLHTLDLTTPLKDAFSEELLSFFPKDKYILQFTGPSGADANEAAIKLAKTYTGRGNIIAFSGGFHGMTQGALAL
TGNLGAKNAVENLMPGVQFMPYPHEYRCPFGIGGEAGAKAVEHYFENFIEDVESGVVKPAAVILEAIQGEGGVVPAPISF
LQKVREVTQKHGILMIVDEVQAGFCRSGRMFAFEHAGIEPDIIVMSKAVGGSLPLAVLAIRKEFDAWQPAGHTGTFRGNQ
LAMATGYASLKIMRDENLAQNAQERGEYLTNALRELSKEYPCIDNVRGRGLMMGIDIVDERQSKDATGAYPRDCELAAAI
QKACFKNKLLLERGGRGGNVVRVLCAVNINQVECEEFIKRFKQSVVDALKVVRS

Sequences:

>Translated_454_residues
MTMITPVQAILASNQHFLDRQDVMESNVRSYPRKLPFAYAKAQGCWVTDVEGNEYLDFLAGAGTLALGHNHPILMQAIKD
VLDSGLPLHTLDLTTPLKDAFSEELLSFFPKDKYILQFTGPSGADANEAAIKLAKTYTGRGNIIAFSGGFHGMTQGALAL
TGNLGAKNAVENLMPGVQFMPYPHEYRCPFGIGGEAGAKAVEHYFENFIEDVESGVVKPAAVILEAIQGEGGVVPAPISF
LQKVREVTQKHGILMIVDEVQAGFCRSGRMFAFEHAGIEPDIIVMSKAVGGSLPLAVLAIRKEFDAWQPAGHTGTFRGNQ
LAMATGYASLKIMRDENLAQNAQERGEYLTNALRELSKEYPCIDNVRGRGLMMGIDIVDERQSKDATGAYPRDCELAAAI
QKACFKNKLLLERGGRGGNVVRVLCAVNINQVECEEFIKRFKQSVVDALKVVRS
>Mature_453_residues
TMITPVQAILASNQHFLDRQDVMESNVRSYPRKLPFAYAKAQGCWVTDVEGNEYLDFLAGAGTLALGHNHPILMQAIKDV
LDSGLPLHTLDLTTPLKDAFSEELLSFFPKDKYILQFTGPSGADANEAAIKLAKTYTGRGNIIAFSGGFHGMTQGALALT
GNLGAKNAVENLMPGVQFMPYPHEYRCPFGIGGEAGAKAVEHYFENFIEDVESGVVKPAAVILEAIQGEGGVVPAPISFL
QKVREVTQKHGILMIVDEVQAGFCRSGRMFAFEHAGIEPDIIVMSKAVGGSLPLAVLAIRKEFDAWQPAGHTGTFRGNQL
AMATGYASLKIMRDENLAQNAQERGEYLTNALRELSKEYPCIDNVRGRGLMMGIDIVDERQSKDATGAYPRDCELAAAIQ
KACFKNKLLLERGGRGGNVVRVLCAVNINQVECEEFIKRFKQSVVDALKVVRS

Specific function: Unknown

COG id: COG0160

COG function: function code E; 4-aminobutyrate aminotransferase and related aminotransferases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI13994255, Length=424, Percent_Identity=30.188679245283, Blast_Score=183, Evalue=2e-46,
Organism=Homo sapiens, GI4557809, Length=427, Percent_Identity=29.03981264637, Blast_Score=158, Evalue=1e-38,
Organism=Homo sapiens, GI24119277, Length=452, Percent_Identity=26.9911504424779, Blast_Score=153, Evalue=4e-37,
Organism=Homo sapiens, GI37574042, Length=397, Percent_Identity=29.4710327455919, Blast_Score=147, Evalue=2e-35,
Organism=Homo sapiens, GI226442705, Length=396, Percent_Identity=28.7878787878788, Blast_Score=142, Evalue=7e-34,
Organism=Homo sapiens, GI226442709, Length=329, Percent_Identity=31.0030395136778, Blast_Score=138, Evalue=1e-32,
Organism=Homo sapiens, GI284507298, Length=340, Percent_Identity=29.1176470588235, Blast_Score=124, Evalue=1e-28,
Organism=Homo sapiens, GI188536080, Length=387, Percent_Identity=28.1653746770026, Blast_Score=114, Evalue=1e-25,
Organism=Homo sapiens, GI38679950, Length=387, Percent_Identity=28.1653746770026, Blast_Score=114, Evalue=1e-25,
Organism=Homo sapiens, GI38679946, Length=387, Percent_Identity=28.1653746770026, Blast_Score=114, Evalue=1e-25,
Organism=Escherichia coli, GI1787560, Length=439, Percent_Identity=33.9407744874715, Blast_Score=216, Evalue=3e-57,
Organism=Escherichia coli, GI1789016, Length=440, Percent_Identity=31.5909090909091, Blast_Score=211, Evalue=8e-56,
Organism=Escherichia coli, GI145693181, Length=408, Percent_Identity=32.5980392156863, Blast_Score=208, Evalue=5e-55,
Organism=Escherichia coli, GI1788044, Length=425, Percent_Identity=30.3529411764706, Blast_Score=162, Evalue=6e-41,
Organism=Escherichia coli, GI1789759, Length=417, Percent_Identity=27.8177458033573, Blast_Score=160, Evalue=1e-40,
Organism=Escherichia coli, GI1786349, Length=348, Percent_Identity=28.735632183908, Blast_Score=134, Evalue=1e-32,
Organism=Escherichia coli, GI1786991, Length=345, Percent_Identity=28.1159420289855, Blast_Score=102, Evalue=5e-23,
Organism=Caenorhabditis elegans, GI32564660, Length=406, Percent_Identity=32.7586206896552, Blast_Score=188, Evalue=4e-48,
Organism=Caenorhabditis elegans, GI71992977, Length=440, Percent_Identity=30, Blast_Score=174, Evalue=9e-44,
Organism=Caenorhabditis elegans, GI25144271, Length=451, Percent_Identity=29.7117516629712, Blast_Score=157, Evalue=2e-38,
Organism=Caenorhabditis elegans, GI25144274, Length=443, Percent_Identity=27.765237020316, Blast_Score=129, Evalue=4e-30,
Organism=Caenorhabditis elegans, GI17541228, Length=383, Percent_Identity=26.6318537859008, Blast_Score=97, Evalue=3e-20,
Organism=Saccharomyces cerevisiae, GI6323470, Length=375, Percent_Identity=32.5333333333333, Blast_Score=164, Evalue=3e-41,
Organism=Saccharomyces cerevisiae, GI6324432, Length=347, Percent_Identity=31.700288184438, Blast_Score=155, Evalue=1e-38,
Organism=Saccharomyces cerevisiae, GI6321456, Length=454, Percent_Identity=27.3127753303965, Blast_Score=124, Evalue=2e-29,
Organism=Drosophila melanogaster, GI28574759, Length=425, Percent_Identity=30.5882352941176, Blast_Score=193, Evalue=2e-49,
Organism=Drosophila melanogaster, GI161085790, Length=436, Percent_Identity=30.2752293577982, Blast_Score=191, Evalue=8e-49,
Organism=Drosophila melanogaster, GI21357415, Length=425, Percent_Identity=28.2352941176471, Blast_Score=151, Evalue=1e-36,
Organism=Drosophila melanogaster, GI21356575, Length=440, Percent_Identity=26.3636363636364, Blast_Score=142, Evalue=5e-34,
Organism=Drosophila melanogaster, GI281366494, Length=392, Percent_Identity=26.530612244898, Blast_Score=104, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24667139, Length=392, Percent_Identity=26.530612244898, Blast_Score=104, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24667143, Length=392, Percent_Identity=26.530612244898, Blast_Score=104, Evalue=1e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005814
- InterPro:   IPR004637
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.76 [H]

Molecular weight: Translated: 49458; Mature: 49327

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTMITPVQAILASNQHFLDRQDVMESNVRSYPRKLPFAYAKAQGCWVTDVEGNEYLDFLA
CCCCHHHHHHHCCCCHHCCHHHHHHHHHHHHHHHCCCHHCCCCCCEEEECCCCHHHHHHH
GAGTLALGHNHPILMQAIKDVLDSGLPLHTLDLTTPLKDAFSEELLSFFPKDKYILQFTG
CCCEEEECCCCHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHCCCCCEEEEECC
PSGADANEAAIKLAKTYTGRGNIIAFSGGFHGMTQGALALTGNLGAKNAVENLMPGVQFM
CCCCCCHHHHHHHHHEECCCCCEEEEECCCCCCCCCCEEEECCCCCHHHHHHHCCCCEEC
PYPHEYRCPFGIGGEAGAKAVEHYFENFIEDVESGVVKPAAVILEAIQGEGGVVPAPISF
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCHHH
LQKVREVTQKHGILMIVDEVQAGFCRSGRMFAFEHAGIEPDIIVMSKAVGGSLPLAVLAI
HHHHHHHHHHCCEEEEEECHHHCCCCCCCEEEEECCCCCCCEEEEECCCCCCCHHHHHHH
RKEFDAWQPAGHTGTFRGNQLAMATGYASLKIMRDENLAQNAQERGEYLTNALRELSKEY
HHHHCCCCCCCCCCCCCCCEEEEEECCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHC
PCIDNVRGRGLMMGIDIVDERQSKDATGAYPRDCELAAAIQKACFKNKLLLERGGRGGNV
CCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHCCCCCCCE
VRVLCAVNINQVECEEFIKRFKQSVVDALKVVRS
EEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TMITPVQAILASNQHFLDRQDVMESNVRSYPRKLPFAYAKAQGCWVTDVEGNEYLDFLA
CCCHHHHHHHCCCCHHCCHHHHHHHHHHHHHHHCCCHHCCCCCCEEEECCCCHHHHHHH
GAGTLALGHNHPILMQAIKDVLDSGLPLHTLDLTTPLKDAFSEELLSFFPKDKYILQFTG
CCCEEEECCCCHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHCCCCCEEEEECC
PSGADANEAAIKLAKTYTGRGNIIAFSGGFHGMTQGALALTGNLGAKNAVENLMPGVQFM
CCCCCCHHHHHHHHHEECCCCCEEEEECCCCCCCCCCEEEECCCCCHHHHHHHCCCCEEC
PYPHEYRCPFGIGGEAGAKAVEHYFENFIEDVESGVVKPAAVILEAIQGEGGVVPAPISF
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCHHH
LQKVREVTQKHGILMIVDEVQAGFCRSGRMFAFEHAGIEPDIIVMSKAVGGSLPLAVLAI
HHHHHHHHHHCCEEEEEECHHHCCCCCCCEEEEECCCCCCCEEEEECCCCCCCHHHHHHH
RKEFDAWQPAGHTGTFRGNQLAMATGYASLKIMRDENLAQNAQERGEYLTNALRELSKEY
HHHHCCCCCCCCCCCCCCCEEEEEECCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHC
PCIDNVRGRGLMMGIDIVDERQSKDATGAYPRDCELAAAIQKACFKNKLLLERGGRGGNV
CCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHCCCCCCCE
VRVLCAVNINQVECEEFIKRFKQSVVDALKVVRS
EEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800; 9514614 [H]