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The map label for this gene is ddc [H]

Identifier: 148828124

GI number: 148828124

Start: 1537685

End: 1539220

Strand: Reverse

Name: ddc [H]

Synonym: CGSHiGG_08300

Alternate gene names: 148828124

Gene position: 1539220-1537685 (Counterclockwise)

Preceding gene: 148828125

Following gene: 148828123

Centisome position: 81.56

GC content: 42.58

Gene sequence:

>1536_bases
ATGTCAAACCTCAAACAACACAAACAAGCTTTGTTTTGCAACGATAACGAAGCCATTAACGATTATGAAACAGCGATGAA
TAATGCGGTGCAAGCAGTCTCTGCTTGGCTGAAAAATGAAAAAATGTACACAGGCGGTTCAATCAAACAAATGCGAGCCT
TAATAAGCGGTTTTAATCCGACGAAAGAGGGTATGGGTGTACAGAAATCACTCGATCATTTGGTAGAAATTTTCCTTAAT
CCAAGCCTTAAAGTACATCATCCACACTCACTTGCCCATTTACATTGCCCAACGATGGTAACAAGCCAAATTGCGGAAGT
GTTGATTAATGCCACCAACCAATCTATGGACTCTTGGGATCAAAGCCCAGCAGGTTCGATTATGGAGGAGCATTTGATCA
ACTGGCTACGCCAAAAAGCAGGCTATGGGGAAGGCACATCAGGCGTGTTCACTTCTGGTGGTACTCAATCTAACTTAATG
GGCGTATTGTTGGCACGCGATTGGGCGATTGCAAACCACTGGAAAAACGAAGACGGCTCTGAATGGTCAGTACAACGTGA
TGGTATTCCAGCAGAAGCGATGCAAAAAGTGAAAGTGATTTGTTCAGAAAACGCACATTTCTCTGTACAAAAAAATATGG
CAATGATGGGCATGGGTTTCCAATCGGTCGTGACCGTGCCATCAAATGCCAATGCACAAATGGATCTTATTGCACTTAAA
CAAACACTTGCACAGCTTAAAGCTGATGGCAAAATTACTGCCTGTATTGTTGCTACCGCAGGCACAACAGATGCTGGCGC
AATTGATGACTTAAAAGCCATCCGCAAACTTGCCGATGAATATCAAGCGTGGTTACACGTTGATGCCGCTTGGGGTGGCG
CATTATTGCTTTCCAAAGATTATCGCTATTTCTTAGATGGTATTGAATTAACTGATTCCATCACGCTTGATTTCCACAAA
CACTTCTTCCAAACGATCTCGTGTGGGGCGTTCTTGTTGAAAGATCCTGCGAACTATCGCTTTATCGATTACAAAGCGGA
TTATCTCAATTCGGAATATGATGAAGCTCACGGCGTGCCAAACTTAGTGGCGAAATCATTACAAACCACACGTCGTTTCG
ACGCATTAAAATTATGGTTTACCCTTGAAGCATTGGGCGAAGATCTTTACGCTTCAATGATCGATCACGGCGTAAAACTG
ACCAAAGAAGTCGAGCAATACATCAACGATACTCCTGCCTTAGAAATGCTTGTGCCAAGTCAGTTTGCATCGGTGTTATT
CCGTGTCGTACCAAAAGACTATCCAGCTGAATTTATTGATGCACTAAACCAAAACGTGGCAGATGAACTCTTTGCTCGAG
GAGAAGCGAATATTGGCGTGACTAAAGTAGGCGACAAACAATCACTGAAAATGACTACCCTAAGCCCGATTGCAACATTG
GAAAATGTTAAAGCGTTATTAACTCAAGTACTAACAGAAGCAAATCGTATTAAAGACGACATCAAAAATAGCACTTACAC
ACCACCCATTGATTAA

Upstream 100 bases:

>100_bases
AGTGAAGGGTTAATTCTGGTTAGTAACAATTTAAGAGAATTTGAGCGAGTTATAGCATTACGTACAGAAAATTGGGTGTA
ATTCATATCTAGGAATAATT

Downstream 100 bases:

>100_bases
TTAGTTAGTCAATTAACACAAAAAATAACCGCTTGTATCTGAAAACAGGCGGTTATTCTGTAAAATAAAAATCTTTTAGC
ATAGATCAAACGAGATATAT

Product: hypothetical protein

Products: NA

Alternate protein names: DABA decarboxylase; DABA-DC [H]

Number of amino acids: Translated: 511; Mature: 510

Protein sequence:

>511_residues
MSNLKQHKQALFCNDNEAINDYETAMNNAVQAVSAWLKNEKMYTGGSIKQMRALISGFNPTKEGMGVQKSLDHLVEIFLN
PSLKVHHPHSLAHLHCPTMVTSQIAEVLINATNQSMDSWDQSPAGSIMEEHLINWLRQKAGYGEGTSGVFTSGGTQSNLM
GVLLARDWAIANHWKNEDGSEWSVQRDGIPAEAMQKVKVICSENAHFSVQKNMAMMGMGFQSVVTVPSNANAQMDLIALK
QTLAQLKADGKITACIVATAGTTDAGAIDDLKAIRKLADEYQAWLHVDAAWGGALLLSKDYRYFLDGIELTDSITLDFHK
HFFQTISCGAFLLKDPANYRFIDYKADYLNSEYDEAHGVPNLVAKSLQTTRRFDALKLWFTLEALGEDLYASMIDHGVKL
TKEVEQYINDTPALEMLVPSQFASVLFRVVPKDYPAEFIDALNQNVADELFARGEANIGVTKVGDKQSLKMTTLSPIATL
ENVKALLTQVLTEANRIKDDIKNSTYTPPID

Sequences:

>Translated_511_residues
MSNLKQHKQALFCNDNEAINDYETAMNNAVQAVSAWLKNEKMYTGGSIKQMRALISGFNPTKEGMGVQKSLDHLVEIFLN
PSLKVHHPHSLAHLHCPTMVTSQIAEVLINATNQSMDSWDQSPAGSIMEEHLINWLRQKAGYGEGTSGVFTSGGTQSNLM
GVLLARDWAIANHWKNEDGSEWSVQRDGIPAEAMQKVKVICSENAHFSVQKNMAMMGMGFQSVVTVPSNANAQMDLIALK
QTLAQLKADGKITACIVATAGTTDAGAIDDLKAIRKLADEYQAWLHVDAAWGGALLLSKDYRYFLDGIELTDSITLDFHK
HFFQTISCGAFLLKDPANYRFIDYKADYLNSEYDEAHGVPNLVAKSLQTTRRFDALKLWFTLEALGEDLYASMIDHGVKL
TKEVEQYINDTPALEMLVPSQFASVLFRVVPKDYPAEFIDALNQNVADELFARGEANIGVTKVGDKQSLKMTTLSPIATL
ENVKALLTQVLTEANRIKDDIKNSTYTPPID
>Mature_510_residues
SNLKQHKQALFCNDNEAINDYETAMNNAVQAVSAWLKNEKMYTGGSIKQMRALISGFNPTKEGMGVQKSLDHLVEIFLNP
SLKVHHPHSLAHLHCPTMVTSQIAEVLINATNQSMDSWDQSPAGSIMEEHLINWLRQKAGYGEGTSGVFTSGGTQSNLMG
VLLARDWAIANHWKNEDGSEWSVQRDGIPAEAMQKVKVICSENAHFSVQKNMAMMGMGFQSVVTVPSNANAQMDLIALKQ
TLAQLKADGKITACIVATAGTTDAGAIDDLKAIRKLADEYQAWLHVDAAWGGALLLSKDYRYFLDGIELTDSITLDFHKH
FFQTISCGAFLLKDPANYRFIDYKADYLNSEYDEAHGVPNLVAKSLQTTRRFDALKLWFTLEALGEDLYASMIDHGVKLT
KEVEQYINDTPALEMLVPSQFASVLFRVVPKDYPAEFIDALNQNVADELFARGEANIGVTKVGDKQSLKMTTLSPIATLE
NVKALLTQVLTEANRIKDDIKNSTYTPPID

Specific function: Unknown

COG id: COG0076

COG function: function code E; Glutamate decarboxylase and related PLP-dependent proteins

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the group II decarboxylase family [H]

Homologues:

Organism=Homo sapiens, GI194294551, Length=369, Percent_Identity=29.5392953929539, Blast_Score=167, Evalue=2e-41,
Organism=Homo sapiens, GI197383062, Length=472, Percent_Identity=25.8474576271186, Blast_Score=163, Evalue=4e-40,
Organism=Homo sapiens, GI197276620, Length=429, Percent_Identity=26.3403263403263, Blast_Score=152, Evalue=6e-37,
Organism=Homo sapiens, GI4503875, Length=429, Percent_Identity=26.3403263403263, Blast_Score=152, Evalue=6e-37,
Organism=Homo sapiens, GI58331246, Length=428, Percent_Identity=25.2336448598131, Blast_Score=146, Evalue=4e-35,
Organism=Homo sapiens, GI4503281, Length=408, Percent_Identity=25.2450980392157, Blast_Score=133, Evalue=3e-31,
Organism=Homo sapiens, GI132814448, Length=408, Percent_Identity=25.2450980392157, Blast_Score=133, Evalue=3e-31,
Organism=Homo sapiens, GI92110055, Length=424, Percent_Identity=25, Blast_Score=129, Evalue=5e-30,
Organism=Caenorhabditis elegans, GI17555682, Length=498, Percent_Identity=26.3052208835341, Blast_Score=155, Evalue=7e-38,
Organism=Caenorhabditis elegans, GI71993062, Length=438, Percent_Identity=26.7123287671233, Blast_Score=154, Evalue=9e-38,
Organism=Caenorhabditis elegans, GI71993058, Length=428, Percent_Identity=26.1682242990654, Blast_Score=145, Evalue=6e-35,
Organism=Caenorhabditis elegans, GI17534819, Length=420, Percent_Identity=24.2857142857143, Blast_Score=110, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI17534817, Length=420, Percent_Identity=24.2857142857143, Blast_Score=110, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI71981211, Length=455, Percent_Identity=21.978021978022, Blast_Score=109, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI71981217, Length=464, Percent_Identity=21.3362068965517, Blast_Score=106, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17551992, Length=468, Percent_Identity=20.5128205128205, Blast_Score=96, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI133931025, Length=393, Percent_Identity=21.6284987277354, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI17136594, Length=438, Percent_Identity=26.9406392694064, Blast_Score=156, Evalue=3e-38,
Organism=Drosophila melanogaster, GI21356415, Length=333, Percent_Identity=30.6306306306306, Blast_Score=149, Evalue=4e-36,
Organism=Drosophila melanogaster, GI24657193, Length=360, Percent_Identity=28.3333333333333, Blast_Score=141, Evalue=8e-34,
Organism=Drosophila melanogaster, GI24657185, Length=360, Percent_Identity=28.3333333333333, Blast_Score=141, Evalue=8e-34,
Organism=Drosophila melanogaster, GI24657188, Length=360, Percent_Identity=28.3333333333333, Blast_Score=141, Evalue=8e-34,
Organism=Drosophila melanogaster, GI17136190, Length=352, Percent_Identity=26.4204545454545, Blast_Score=128, Evalue=1e-29,
Organism=Drosophila melanogaster, GI24585135, Length=334, Percent_Identity=26.6467065868263, Blast_Score=123, Evalue=3e-28,
Organism=Drosophila melanogaster, GI24585139, Length=423, Percent_Identity=24.5862884160757, Blast_Score=117, Evalue=2e-26,
Organism=Drosophila melanogaster, GI221476190, Length=423, Percent_Identity=24.5862884160757, Blast_Score=117, Evalue=2e-26,
Organism=Drosophila melanogaster, GI24585143, Length=423, Percent_Identity=24.5862884160757, Blast_Score=117, Evalue=2e-26,
Organism=Drosophila melanogaster, GI24652373, Length=425, Percent_Identity=24.7058823529412, Blast_Score=116, Evalue=4e-26,
Organism=Drosophila melanogaster, GI24586044, Length=419, Percent_Identity=24.3436754176611, Blast_Score=107, Evalue=3e-23,
Organism=Drosophila melanogaster, GI28573972, Length=431, Percent_Identity=23.2018561484919, Blast_Score=97, Evalue=3e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002129
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422
- InterPro:   IPR021115 [H]

Pfam domain/function: PF00282 Pyridoxal_deC [H]

EC number: =4.1.1.86 [H]

Molecular weight: Translated: 56544; Mature: 56413

Theoretical pI: Translated: 5.43; Mature: 5.43

Prosite motif: PS00392 DDC_GAD_HDC_YDC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNLKQHKQALFCNDNEAINDYETAMNNAVQAVSAWLKNEKMYTGGSIKQMRALISGFNP
CCCHHHHHHHEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCEECCCCHHHHHHHHCCCCC
TKEGMGVQKSLDHLVEIFLNPSLKVHHPHSLAHLHCPTMVTSQIAEVLINATNQSMDSWD
CHHCCCHHHHHHHHHHHHHCCCEEEECCCCHHHEECHHHHHHHHHHHHHHHCCCCHHHCC
QSPAGSIMEEHLINWLRQKAGYGEGTSGVFTSGGTQSNLMGVLLARDWAIANHWKNEDGS
CCCCHHHHHHHHHHHHHHHCCCCCCCCCCEECCCCHHHHHHHHHHHHHHHHHCCCCCCCC
EWSVQRDGIPAEAMQKVKVICSENAHFSVQKNMAMMGMGFQSVVTVPSNANAQMDLIALK
CCEEECCCCCHHHHHHHHHHHCCCCCEEHHCCHHHHCCCHHHEEECCCCCCCCHHHHHHH
QTLAQLKADGKITACIVATAGTTDAGAIDDLKAIRKLADEYQAWLHVDAAWGGALLLSKD
HHHHHHHCCCCEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHEEEECCCCCEEEEECC
YRYFLDGIELTDSITLDFHKHFFQTISCGAFLLKDPANYRFIDYKADYLNSEYDEAHGVP
HHHHHCCCCCCCCEEHHHHHHHHHHHHCCHHEEECCCCCEEEEEEHHHCCCCHHHHCCCH
NLVAKSLQTTRRFDALKLWFTLEALGEDLYASMIDHGVKLTKEVEQYINDTPALEMLVPS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHCCHH
QFASVLFRVVPKDYPAEFIDALNQNVADELFARGEANIGVTKVGDKQSLKMTTLSPIATL
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCEEEECCCHHHHH
ENVKALLTQVLTEANRIKDDIKNSTYTPPID
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
SNLKQHKQALFCNDNEAINDYETAMNNAVQAVSAWLKNEKMYTGGSIKQMRALISGFNP
CCHHHHHHHEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCEECCCCHHHHHHHHCCCCC
TKEGMGVQKSLDHLVEIFLNPSLKVHHPHSLAHLHCPTMVTSQIAEVLINATNQSMDSWD
CHHCCCHHHHHHHHHHHHHCCCEEEECCCCHHHEECHHHHHHHHHHHHHHHCCCCHHHCC
QSPAGSIMEEHLINWLRQKAGYGEGTSGVFTSGGTQSNLMGVLLARDWAIANHWKNEDGS
CCCCHHHHHHHHHHHHHHHCCCCCCCCCCEECCCCHHHHHHHHHHHHHHHHHCCCCCCCC
EWSVQRDGIPAEAMQKVKVICSENAHFSVQKNMAMMGMGFQSVVTVPSNANAQMDLIALK
CCEEECCCCCHHHHHHHHHHHCCCCCEEHHCCHHHHCCCHHHEEECCCCCCCCHHHHHHH
QTLAQLKADGKITACIVATAGTTDAGAIDDLKAIRKLADEYQAWLHVDAAWGGALLLSKD
HHHHHHHCCCCEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHEEEECCCCCEEEEECC
YRYFLDGIELTDSITLDFHKHFFQTISCGAFLLKDPANYRFIDYKADYLNSEYDEAHGVP
HHHHHCCCCCCCCEEHHHHHHHHHHHHCCHHEEECCCCCEEEEEEHHHCCCCHHHHCCCH
NLVAKSLQTTRRFDALKLWFTLEALGEDLYASMIDHGVKLTKEVEQYINDTPALEMLVPS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHCCHH
QFASVLFRVVPKDYPAEFIDALNQNVADELFARGEANIGVTKVGDKQSLKMTTLSPIATL
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCEEEECCCHHHHH
ENVKALLTQVLTEANRIKDDIKNSTYTPPID
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800; 9514614 [H]