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The map label for this gene is ribD [H]

Identifier: 148828121

GI number: 148828121

Start: 1534423

End: 1535541

Strand: Direct

Name: ribD [H]

Synonym: CGSHiGG_08285

Alternate gene names: 148828121

Gene position: 1534423-1535541 (Clockwise)

Preceding gene: 148828120

Following gene: 148828122

Centisome position: 81.31

GC content: 40.84

Gene sequence:

>1119_bases
ATGCTTGAATTCTCCTCACAAGATTGCGTATTTATGCAACGTGCCTTAGATTTAGCCGCCAAAGGTCAATATACCACTAC
ACCGAACCCATCGGTGGGATGCGTATTGGTTAAAAATGGTGAAATTGTGGGGGAGGGCTTTCATTTTAAGGCAGGACAAC
CTCATGCTGAACGTGTTGCCTTAGCTCAAGCTGGTGAAAATGCTAAAGGAGCAACCGCTTACGTCACCTTAGAGCCTTGT
GCTCATTATGGTCGCACACCGCCTTGTGCATTAGGATTAATTGAGGCAGGCGTAGTGAAAGTCATTGCAGCTATGCAAGA
TCCAAATCCTCAAGTCGCAGGAAAAGGTTTGAAAATGTTGTCTGATGCTGGTATCGAAAGTGCGGTGAATTTATTAAACG
ATCAAGCGGAAAAAATAAATAAAGGTTTTTTAAAACGAATGCGTCAAGGTATGCCTTTTGTTCAACTCAAACTCGCCATG
AGTTTAGATGGACGAACTGCAATGGCAAGTGGAGAAAGTAAATGGATTACAGGCCCAGATGCTCGTTCGGACGTACAAAA
AATGCGAGCAAAATCATCCGCACTTTTATCTACTTCCACAACAGTCATTGCAGATGATCCAAGCCTGAACGTACGCTGGG
ATGAATTTCCTGAAACTCTAAAAACAGAATATAAAAAAGAAGATCTTCGCCAGCCCGTGCGAGTCATTTTAGATTCACAA
CATCGCATTCAGCCGACTCATAAACTTTTTTTAACCCATTCTCCCGTTTGGTTAGTCTCTAGTGAGCCACGAGATTTAAC
AGGCTTTCCTGATTTTTGTGAACAAATTATTCTTCCGAAAGAAAATTTACTAAAAGAATTAATGCGAGAACTGGGAAAAC
GACAAATCAATACCCTTTGGGTAGAAGCTGGAGCAAATTTAGCGGGCAGTTTAATTGATGCGAAATTAGTGGATGAATTG
ATTATTTACATTGCGCCAAAATTACTTGGAGACAATGCTCGTGGTTTATGCCAATTACCGAATTTAACTAAACTTGCCGA
TGCACCATTATGGCAACTCAATGAATTAGAACAAATCGGTGACGATATAAAATTAACTTACACACCGAAAGGAGTCTAA

Upstream 100 bases:

>100_bases
AACTCGATAAAGTGGCTTATATTCGTTTTGCATCAGTCTATTTAAGTTTTGATGATATTGATCAATTCACTATCGAAATT
GAAAAATTAAAGGATTAATT

Downstream 100 bases:

>100_bases
ATGCTTAAAAAACTTTTCCATTCCGCACTTTGGGGCTTGGCTGCTGCGGGCGTGATTTTGTTTGCGGTTCCAAGACTGAA
TAACAGCAATATCTTCACTT

Product: hypothetical protein

Products: NA

Alternate protein names: Diaminohydroxyphosphoribosylaminopyrimidine deaminase; DRAP deaminase; Riboflavin-specific deaminase; 5-amino-6-(5-phosphoribosylamino)uracil reductase; HTP reductase [H]

Number of amino acids: Translated: 372; Mature: 372

Protein sequence:

>372_residues
MLEFSSQDCVFMQRALDLAAKGQYTTTPNPSVGCVLVKNGEIVGEGFHFKAGQPHAERVALAQAGENAKGATAYVTLEPC
AHYGRTPPCALGLIEAGVVKVIAAMQDPNPQVAGKGLKMLSDAGIESAVNLLNDQAEKINKGFLKRMRQGMPFVQLKLAM
SLDGRTAMASGESKWITGPDARSDVQKMRAKSSALLSTSTTVIADDPSLNVRWDEFPETLKTEYKKEDLRQPVRVILDSQ
HRIQPTHKLFLTHSPVWLVSSEPRDLTGFPDFCEQIILPKENLLKELMRELGKRQINTLWVEAGANLAGSLIDAKLVDEL
IIYIAPKLLGDNARGLCQLPNLTKLADAPLWQLNELEQIGDDIKLTYTPKGV

Sequences:

>Translated_372_residues
MLEFSSQDCVFMQRALDLAAKGQYTTTPNPSVGCVLVKNGEIVGEGFHFKAGQPHAERVALAQAGENAKGATAYVTLEPC
AHYGRTPPCALGLIEAGVVKVIAAMQDPNPQVAGKGLKMLSDAGIESAVNLLNDQAEKINKGFLKRMRQGMPFVQLKLAM
SLDGRTAMASGESKWITGPDARSDVQKMRAKSSALLSTSTTVIADDPSLNVRWDEFPETLKTEYKKEDLRQPVRVILDSQ
HRIQPTHKLFLTHSPVWLVSSEPRDLTGFPDFCEQIILPKENLLKELMRELGKRQINTLWVEAGANLAGSLIDAKLVDEL
IIYIAPKLLGDNARGLCQLPNLTKLADAPLWQLNELEQIGDDIKLTYTPKGV
>Mature_372_residues
MLEFSSQDCVFMQRALDLAAKGQYTTTPNPSVGCVLVKNGEIVGEGFHFKAGQPHAERVALAQAGENAKGATAYVTLEPC
AHYGRTPPCALGLIEAGVVKVIAAMQDPNPQVAGKGLKMLSDAGIESAVNLLNDQAEKINKGFLKRMRQGMPFVQLKLAM
SLDGRTAMASGESKWITGPDARSDVQKMRAKSSALLSTSTTVIADDPSLNVRWDEFPETLKTEYKKEDLRQPVRVILDSQ
HRIQPTHKLFLTHSPVWLVSSEPRDLTGFPDFCEQIILPKENLLKELMRELGKRQINTLWVEAGANLAGSLIDAKLVDEL
IIYIAPKLLGDNARGLCQLPNLTKLADAPLWQLNELEQIGDDIKLTYTPKGV

Specific function: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate [H]

COG id: COG1985

COG function: function code H; Pyrimidine reductase, riboflavin biosynthesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the HTP reductase family [H]

Homologues:

Organism=Escherichia coli, GI1786616, Length=362, Percent_Identity=57.182320441989, Blast_Score=438, Evalue=1e-124,
Organism=Saccharomyces cerevisiae, GI6319629, Length=218, Percent_Identity=26.605504587156, Blast_Score=66, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193
- InterPro:   IPR004794
- InterPro:   IPR011549
- InterPro:   IPR002734 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1; PF01872 RibD_C [H]

EC number: =3.5.4.26; =1.1.1.193 [H]

Molecular weight: Translated: 40768; Mature: 40768

Theoretical pI: Translated: 6.78; Mature: 6.78

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLEFSSQDCVFMQRALDLAAKGQYTTTPNPSVGCVLVKNGEIVGEGFHFKAGQPHAERVA
CCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCEEEECCEEECCCCCHHHHHH
LAQAGENAKGATAYVTLEPCAHYGRTPPCALGLIEAGVVKVIAAMQDPNPQVAGKGLKML
HHHCCCCCCCCEEEEEECCHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHCCHHHHH
SDAGIESAVNLLNDQAEKINKGFLKRMRQGMPFVQLKLAMSLDGRTAMASGESKWITGPD
HHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCEEECCCCCCCCCCCC
ARSDVQKMRAKSSALLSTSTTVIADDPSLNVRWDEFPETLKTEYKKEDLRQPVRVILDSQ
HHHHHHHHHHHHHHHEECCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
HRIQPTHKLFLTHSPVWLVSSEPRDLTGFPDFCEQIILPKENLLKELMRELGKRQINTLW
CCCCCCCEEEEECCCEEEEECCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHEEE
VEAGANLAGSLIDAKLVDELIIYIAPKLLGDNARGLCQLPNLTKLADAPLWQLNELEQIG
EECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCHHHHCCCCHHHHHHHHCC
DDIKLTYTPKGV
CCEEEEECCCCC
>Mature Secondary Structure
MLEFSSQDCVFMQRALDLAAKGQYTTTPNPSVGCVLVKNGEIVGEGFHFKAGQPHAERVA
CCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCEEEECCEEECCCCCHHHHHH
LAQAGENAKGATAYVTLEPCAHYGRTPPCALGLIEAGVVKVIAAMQDPNPQVAGKGLKML
HHHCCCCCCCCEEEEEECCHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHCCHHHHH
SDAGIESAVNLLNDQAEKINKGFLKRMRQGMPFVQLKLAMSLDGRTAMASGESKWITGPD
HHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCEEECCCCCCCCCCCC
ARSDVQKMRAKSSALLSTSTTVIADDPSLNVRWDEFPETLKTEYKKEDLRQPVRVILDSQ
HHHHHHHHHHHHHHHEECCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
HRIQPTHKLFLTHSPVWLVSSEPRDLTGFPDFCEQIILPKENLLKELMRELGKRQINTLW
CCCCCCCEEEEECCCEEEEECCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHEEE
VEAGANLAGSLIDAKLVDELIIYIAPKLLGDNARGLCQLPNLTKLADAPLWQLNELEQIG
EECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCHHHHCCCCHHHHHHHHCC
DDIKLTYTPKGV
CCEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]