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The map label for this gene is lic2B [H]

Identifier: 148827740

GI number: 148827740

Start: 1093430

End: 1094266

Strand: Direct

Name: lic2B [H]

Synonym: CGSHiGG_06005

Alternate gene names: 148827740

Gene position: 1093430-1094266 (Clockwise)

Preceding gene: 148827734

Following gene: 148827741

Centisome position: 57.94

GC content: 29.51

Gene sequence:

>837_bases
ATGCAAAAGCCTTTTCTCAGTAAGTATGATCCTCAAATGCATATAAATTACGTTATTAGTCTTACTTCAGCATATCAACG
ACGAGAGCATATTCAAAAAGAATTCTCTCAACAAAACATTCCTTTTGAATTTTTTGATGCTTTAAAACCTTCAAAAGAAC
TAACCTCGTTAATAGAAAAATTTATCCCTAATCTACTCCATGCAAAGTTAACTGAGGGAGAAAAAGCATGTTTTATGAGC
CATTACATGCTATGGCAAAAATGCTTGTCCGAAGATCTACCCTATATTTACATTTTTGAAGATGATGTATTATTAGGTGA
GAATGCAGACAAATTTCTAGCTGAAGATGAATGGTTAGAAGAACGTTTTAAACAAACTGATAAATTTATTTTAAGATTTG
AAACATTCCTAAATTTTTCTAAATGTAAAGATAAAAAAATTAAACCTTATTCAGGTAGAAAAATATTAAAACTAGTATCA
GAAAATTGTGGCACCGCAGGGTATGTTATATCTAGAGAAGCAGTTAAACAACTAAGTGCTCATATCTGTTCGCTCACATC
CAACCATCTACTCGCGATAGATTTATTAATATTTAATATATTTAATCAGTCTACATACCAGGTATCACCAGGTGTATGTG
TTCAAGAAGAACAGCTATATCCAAAGGATATAAAATTACATAGTCAGTTAGAAACGGAAAGACAAAAATATCTTAGTGTA
AAGAAAAAAAGAACACTAAAAACAGTATTAATATCTTTAGCAGGAAAACCTAAAAAAATATTGAGAAAAATATACAGAAA
GCTATTTATTTCTAAACACATAGTACCATTTAGATAA

Upstream 100 bases:

>100_bases
TTTAGGCGGAAAAGTTAAGAAAAACGGGCGGATTATAGCCGTTTTTAATGTTAGACGAAAGATTAAAATAAAATTGAACA
GAAAAAAAATAACCCCTATA

Downstream 100 bases:

>100_bases
TCCAACATTATACTTTGATAAAGTAAAAATATGACTAAATTAATAACAATTTCACTAACTTGCCAAAAATTTCAATATGG
CGGAGGAATGGAAAGATATC

Product: lipooligosaccharide galactosyltransferase II

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 278; Mature: 278

Protein sequence:

>278_residues
MQKPFLSKYDPQMHINYVISLTSAYQRREHIQKEFSQQNIPFEFFDALKPSKELTSLIEKFIPNLLHAKLTEGEKACFMS
HYMLWQKCLSEDLPYIYIFEDDVLLGENADKFLAEDEWLEERFKQTDKFILRFETFLNFSKCKDKKIKPYSGRKILKLVS
ENCGTAGYVISREAVKQLSAHICSLTSNHLLAIDLLIFNIFNQSTYQVSPGVCVQEEQLYPKDIKLHSQLETERQKYLSV
KKKRTLKTVLISLAGKPKKILRKIYRKLFISKHIVPFR

Sequences:

>Translated_278_residues
MQKPFLSKYDPQMHINYVISLTSAYQRREHIQKEFSQQNIPFEFFDALKPSKELTSLIEKFIPNLLHAKLTEGEKACFMS
HYMLWQKCLSEDLPYIYIFEDDVLLGENADKFLAEDEWLEERFKQTDKFILRFETFLNFSKCKDKKIKPYSGRKILKLVS
ENCGTAGYVISREAVKQLSAHICSLTSNHLLAIDLLIFNIFNQSTYQVSPGVCVQEEQLYPKDIKLHSQLETERQKYLSV
KKKRTLKTVLISLAGKPKKILRKIYRKLFISKHIVPFR
>Mature_278_residues
MQKPFLSKYDPQMHINYVISLTSAYQRREHIQKEFSQQNIPFEFFDALKPSKELTSLIEKFIPNLLHAKLTEGEKACFMS
HYMLWQKCLSEDLPYIYIFEDDVLLGENADKFLAEDEWLEERFKQTDKFILRFETFLNFSKCKDKKIKPYSGRKILKLVS
ENCGTAGYVISREAVKQLSAHICSLTSNHLLAIDLLIFNIFNQSTYQVSPGVCVQEEQLYPKDIKLHSQLETERQKYLSV
KKKRTLKTVLISLAGKPKKILRKIYRKLFISKHIVPFR

Specific function: Involved in extracellular lipooligosaccharide (LOS) biosynthesis and virulence expression. Involved in the synthesis of the oligosaccharide moiety of the LOS molecule by adding GalNAc [H]

COG id: COG3306

COG function: function code M; Glycosyltransferase involved in LPS biosynthesis

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 25 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002654 [H]

Pfam domain/function: PF01755 Glyco_transf_25 [H]

EC number: NA

Molecular weight: Translated: 32731; Mature: 32731

Theoretical pI: Translated: 9.66; Mature: 9.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKPFLSKYDPQMHINYVISLTSAYQRREHIQKEFSQQNIPFEFFDALKPSKELTSLIEK
CCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCHHHHHHHHHH
FIPNLLHAKLTEGEKACFMSHYMLWQKCLSEDLPYIYIFEDDVLLGENADKFLAEDEWLE
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCEEECCCCHHHHHHHHHHH
ERFKQTDKFILRFETFLNFSKCKDKKIKPYSGRKILKLVSENCGTAGYVISREAVKQLSA
HHHHHHHHHHHHHHHHHCHHHHCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHH
HICSLTSNHLLAIDLLIFNIFNQSTYQVSPGVCVQEEQLYPKDIKLHSQLETERQKYLSV
HHHHHCCCCHHHHHHHHHHHHCCCCEEECCCCEECCCCCCCHHHHHHHHHHHHHHHHHHH
KKKRTLKTVLISLAGKPKKILRKIYRKLFISKHIVPFR
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MQKPFLSKYDPQMHINYVISLTSAYQRREHIQKEFSQQNIPFEFFDALKPSKELTSLIEK
CCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCHHHHHHHHHH
FIPNLLHAKLTEGEKACFMSHYMLWQKCLSEDLPYIYIFEDDVLLGENADKFLAEDEWLE
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCEEECCCCHHHHHHHHHHH
ERFKQTDKFILRFETFLNFSKCKDKKIKPYSGRKILKLVSENCGTAGYVISREAVKQLSA
HHHHHHHHHHHHHHHHHCHHHHCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHH
HICSLTSNHLLAIDLLIFNIFNQSTYQVSPGVCVQEEQLYPKDIKLHSQLETERQKYLSV
HHHHHCCCCHHHHHHHHHHHHCCCCEEECCCCEECCCCCCCHHHHHHHHHHHHHHHHHHH
KKKRTLKTVLISLAGKPKKILRKIYRKLFISKHIVPFR
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8861214 [H]