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The map label for this gene is rpoB [H]

Identifier: 148827706

GI number: 148827706

Start: 1058807

End: 1062745

Strand: Reverse

Name: rpoB [H]

Synonym: CGSHiGG_05825

Alternate gene names: 148827706

Gene position: 1062745-1058807 (Counterclockwise)

Preceding gene: 148827707

Following gene: 148827705

Centisome position: 56.31

GC content: 39.71

Gene sequence:

>3939_bases
TTGGATTCTTTTGATAAATTTATTCAAAAAGATCCTGAAGGTCAGCAAGGTTTAGAAGCGGCATTTCGTTCTGTATTCCC
TATTGTAAGCAATAATGGCTATACAGAATTACAATATGTAGATTATCGTTTAGAAGAGCCAGAGTTTGATGTACGTGAGT
GCCAAATTCGTGGCTCAACTTATGCAGCAGGCTTACGTGTAAAATTACGTTTAGTGAGCTACGATAAAGAATCTTCTTCA
CGCGCAGTTAAAGATATTAAAGAAAATGAAGTTTATATGGGGGAAATCCCATTAATGACTGATAACGGTACTTTTGTAAT
TAATGGTACCGAGCGTGTTATCGTTTCACAATTACACCGTAGTCCGGGTGTATTCTTCGATTCTGACAAAGGTAAAACCC
ATTCTTCAGGTAAAGTGCTTTATAACGCACGCATTATTCCTTACCGTGGTTCTTGGTTAGATTTTGAATTCGATCCAAAA
GATAACTTATTTGCGCGCATTGACCGTCGCCGTAAATTACCAGCAACAATCATTCTTCGTGCATTAGGCTACACCACTGA
AGAAATTTTAAACTTATTCTTTGATAAAATTACCTTTGAAATCGCTGGCGATAAATTGTTAATGACTTTAGTGCCAGAAC
GTTTACGTGGTGAAACGGCTTCTTTTGATATTGAAGCAAATGGCAAAGTGTATGTTGAACGTGGTCGTCGCATCACTGCT
CGTCACATTAAAGCATTAGAAAAAGATAATATCTCACAAGTGGTTGTGCCTTCTGAATATATTTTAGGTAAAGTTGCGTC
GAAAGATTATGTTGATTTAGAGTCTGGCGAAATTATTTGTCCTGCAAATGGTGAAATTTCGTTAGAAACCCTCGCAAAAT
TAGCACAAGCTGGTTACACCACGATCGAAACTTTATTTACTAATGATTTAGATTACGGTCCATATATTTCTGAAACGCTA
CGTGTCGATCCAACTTATGACAAAATCAGTGCGCTTTACGAAATTTATCGTATGATGCGTCCGGGCGAGCCACCAACACC
AGAATCTTCAGAAGCGTTATTCAATAATTTATTCTTCTCTGCAGAACGTTATGATTTATCTACAGTAGGTCGTATGAAGT
TCAACCGTTCTTTAGCTTTTCCAGAAGGGGAAGGTGCGGGTATTTTAAGCAATGAAGATATTATTGCGGTAATGCGTAAA
TTGATCGACATCCGTAATGGTCGTGGCGAAGTAGACGATATTGACCATTTGGGTAACCGTCGTATCCGTAGCGTGGGCGA
AATGGCTGAAAACCAATTCCGTATCGGTTTAGTGCGTGTTGAAAGAGCGGTCAAAGAACGTCTATCTTTAGGCGATTTAG
ATGCGATCACGCCACAAGACTTAATTAACCCGAAACCGATTTCTGCGGCAGTAAAAGAATTCTTTGGTTCTTCACAGCTT
TCGCAATTTATGGATCAAAACAACCCATTGTCAGAAGTGACACACAAACGTCGTATTTCTGCATTAGGTCCAGGCGGTTT
AACGCGTGAGCGTGCAGGCTTTGAAGTGCGTGACGTACATAATACTCACTATGGTCGTTTATGTCCGATTGAAACCCCTG
AAGGTCCAAACATCGGTTTGATCAACTCACTTTCTGCTTTTGCACGTACTAATGATTATGGTTTCTTAGAAACACCATAT
CGTAAAGTGGTTGATGGTCAAGTTACTGAAGAAATTGAATACTTATCTGTAATTGATGAAGCAAACTACATCATTGCACA
GGCAAACTCAAACTTAGACGAAAATAACCGTTTTACTGATGCTTTCGTTACTGCTCGTGGTGAACGTGGTGAATCTGGTT
TATATAAACCTGAAGATATTCACTATATGGATGTTTCGACACAACAAGTGGTATCTGTTGCGGCTGCATTAATTCCATTC
CTTGAGCATGACGATGCGAACCGTGCGTTGATGGGTGCGAACATGCAACGTCAAGCAGTTCCAACATTACGTGCGGATAA
ACCATTAGTTGGTACAGGTATGGAAAAACCAATCGCACTTGACTCAGGTGTTGCGGTTGTTGCAAAACGTGGTGGTACCG
TTCAGTACGTTGATGCGTCTCGTATTGTGATTAAAGTAAATGAAGATGAGACTATTGCAGGTGAAGCTGGTATTGATATT
TATAATTTAATTAAATACACCCGCTCTAACCAAAATACTTGTATTAACCAAATTCCTTGTGTGAATTTAGGCGATCCAAT
TAATCGTGGCGAAGTATTAGCAGATGGTCCTTCAACTGATTTAGGGGAACTTGCATTAGGTCAAAATATTCGCGTAGCGT
TCATGCCTTGGAACGGCTATAACTTTGAAGACTCAATGTTAGTTTCTGAACGTGTTGTTCAACAAGACCGTTTCACTACG
ATCCATATTCAAGAATTATCTTGTGTTGCGCGTGATACTAAGTTAGGTGCAGAAGAAATTACTGCGGATATTCCAAACGT
AGGTGAATCAGCGTTAAGCAAACTTGATGAATCTGGTATCGTTTATGTCGGTGCTGAGGTTAAAGGTGGCGACATCTTAG
TAGGTAAAGTAACCCCTAAAGGCGAAACTCAATTAACCCCAGAAGAAAAATTGTTACGTGCAATCTTTGGGGAAAAAGCT
TCCGATGTGAAAGATTCTTCATTACGCGTGCCAAATGGTACATCAGGTACGGTTATTGATGTTCAAGTCTTCACTCGTGA
TGGCGTAGAAAAAGATAAACGTGCATTAGAAATCGAAGAAATGCAACTTCGTGAAGCGAAAAAAGATTTAACTGAAGAGT
TAGAGATTTTAGAAGCTGGTTTATTTGCTCGTGTGCGTAATCTTCTTATTTCTAGTGGTGCGGATGCAGCACAATTAGAT
AAAGTAGATCGCACTAAATGGTTAGAACAAACCATTGCAGATGAAGAAAAACAAAACCAATTAGAACAGCTTGCTGAGCA
ATACGAAGAACTTCGTAAAGAGTTTGAACATAAACTTGAAGTGAAACGTAAGAAAATCATTAAAGGCGATGATCTTGCAC
CGGGCGTATTAAAAGTTGTGAAAGTTTACCTTGCAGTGAAACGTCAAATCCAGCCGGGGGATAAAATGGCGGGTCGTCAC
GGTAACAAAGGTGTTATCTCGAAAATTAACCCAGTTGAAGATATGCCATACGATGAAAATGGTCAGCCAGTTGAAATCGT
ATTAAACCCACTGGGCGTACCGTCTCGTATGAACATCGGTCAGATCCTTGAAACTCACTTAGGTTTAGCTGCAAAAGGTA
TTGGTGATCAAATCAATGCAATGCTTAAACAAAAACAAGAAGTGGAAAAATTACGTAGCTATATCCAAAAAGCATACGAT
TTATTAGGTAATGGTTCACAAAAAGTGGATTTAAGCACTTTTACTGATGAAGAAGTATTGCGTTTAGCGGGAAATTTACG
TAAAGGCTTACCAGTTGCAACGCCAGTGTTCGATGGTGCAGACGAAGCGGAAATCAAAGAACTATTAAAACTTGGTGGAT
TACCAACTTCAGGTCAAATAACCCTTTACGATGGTCGTACTGGCGAGAAATTTGAACGTCCAGTAACCGTGGGTTATATG
TATATGCTCAAATTGAACCACTTAGTTGATGATAAAATGCACGCTCGTTCAACAGGTTCTTATAGCCTTGTTACACAACA
GCCATTGGGTGGTAAAGCACAATTTGGTGGTCAGCGTTTCGGTGAGATGGAGGTTTGGGCACTTGAAGCATATGGTGCAG
CCTACACCTTACAAGAAATGCTAACTGTGAAATCCGATGATGTGAATGGTCGTACGAAGATGTATAAAAATATCGTAAGT
GGCAACCAACATATGGAGCCAGGCACACCGGAATCTTTCAACGTAATTATGAAAGAAATCCGCTCACTTGGTTTAAATAT
CGAGTTAGACGAAGAGTAA

Upstream 100 bases:

>100_bases
GAAAACCAATGGGTTACTCCTATTCTGAAAAAAACGAATTCGTAAAGATTTCGGTAAACGTCCGCAAGTTTTAAATGTTC
CTTATTTATTAACCATTCAG

Downstream 100 bases:

>100_bases
TTTCATTCTTGCCTTCCCCTGCTTGCGGGGGAAGGTGCCCGAAGGGCGGAAGGGGGAAATTCCCCCCCTCAGCCTGCGGC
AGCTCCCCCCGTAAACAGGG

Product: DNA-directed RNA polymerase subunit beta

Products: NA

Alternate protein names: RNAP subunit beta; RNA polymerase subunit beta; Transcriptase subunit beta [H]

Number of amino acids: Translated: 1312; Mature: 1312

Protein sequence:

>1312_residues
MDSFDKFIQKDPEGQQGLEAAFRSVFPIVSNNGYTELQYVDYRLEEPEFDVRECQIRGSTYAAGLRVKLRLVSYDKESSS
RAVKDIKENEVYMGEIPLMTDNGTFVINGTERVIVSQLHRSPGVFFDSDKGKTHSSGKVLYNARIIPYRGSWLDFEFDPK
DNLFARIDRRRKLPATIILRALGYTTEEILNLFFDKITFEIAGDKLLMTLVPERLRGETASFDIEANGKVYVERGRRITA
RHIKALEKDNISQVVVPSEYILGKVASKDYVDLESGEIICPANGEISLETLAKLAQAGYTTIETLFTNDLDYGPYISETL
RVDPTYDKISALYEIYRMMRPGEPPTPESSEALFNNLFFSAERYDLSTVGRMKFNRSLAFPEGEGAGILSNEDIIAVMRK
LIDIRNGRGEVDDIDHLGNRRIRSVGEMAENQFRIGLVRVERAVKERLSLGDLDAITPQDLINPKPISAAVKEFFGSSQL
SQFMDQNNPLSEVTHKRRISALGPGGLTRERAGFEVRDVHNTHYGRLCPIETPEGPNIGLINSLSAFARTNDYGFLETPY
RKVVDGQVTEEIEYLSVIDEANYIIAQANSNLDENNRFTDAFVTARGERGESGLYKPEDIHYMDVSTQQVVSVAAALIPF
LEHDDANRALMGANMQRQAVPTLRADKPLVGTGMEKPIALDSGVAVVAKRGGTVQYVDASRIVIKVNEDETIAGEAGIDI
YNLIKYTRSNQNTCINQIPCVNLGDPINRGEVLADGPSTDLGELALGQNIRVAFMPWNGYNFEDSMLVSERVVQQDRFTT
IHIQELSCVARDTKLGAEEITADIPNVGESALSKLDESGIVYVGAEVKGGDILVGKVTPKGETQLTPEEKLLRAIFGEKA
SDVKDSSLRVPNGTSGTVIDVQVFTRDGVEKDKRALEIEEMQLREAKKDLTEELEILEAGLFARVRNLLISSGADAAQLD
KVDRTKWLEQTIADEEKQNQLEQLAEQYEELRKEFEHKLEVKRKKIIKGDDLAPGVLKVVKVYLAVKRQIQPGDKMAGRH
GNKGVISKINPVEDMPYDENGQPVEIVLNPLGVPSRMNIGQILETHLGLAAKGIGDQINAMLKQKQEVEKLRSYIQKAYD
LLGNGSQKVDLSTFTDEEVLRLAGNLRKGLPVATPVFDGADEAEIKELLKLGGLPTSGQITLYDGRTGEKFERPVTVGYM
YMLKLNHLVDDKMHARSTGSYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVNGRTKMYKNIVS
GNQHMEPGTPESFNVIMKEIRSLGLNIELDEE

Sequences:

>Translated_1312_residues
MDSFDKFIQKDPEGQQGLEAAFRSVFPIVSNNGYTELQYVDYRLEEPEFDVRECQIRGSTYAAGLRVKLRLVSYDKESSS
RAVKDIKENEVYMGEIPLMTDNGTFVINGTERVIVSQLHRSPGVFFDSDKGKTHSSGKVLYNARIIPYRGSWLDFEFDPK
DNLFARIDRRRKLPATIILRALGYTTEEILNLFFDKITFEIAGDKLLMTLVPERLRGETASFDIEANGKVYVERGRRITA
RHIKALEKDNISQVVVPSEYILGKVASKDYVDLESGEIICPANGEISLETLAKLAQAGYTTIETLFTNDLDYGPYISETL
RVDPTYDKISALYEIYRMMRPGEPPTPESSEALFNNLFFSAERYDLSTVGRMKFNRSLAFPEGEGAGILSNEDIIAVMRK
LIDIRNGRGEVDDIDHLGNRRIRSVGEMAENQFRIGLVRVERAVKERLSLGDLDAITPQDLINPKPISAAVKEFFGSSQL
SQFMDQNNPLSEVTHKRRISALGPGGLTRERAGFEVRDVHNTHYGRLCPIETPEGPNIGLINSLSAFARTNDYGFLETPY
RKVVDGQVTEEIEYLSVIDEANYIIAQANSNLDENNRFTDAFVTARGERGESGLYKPEDIHYMDVSTQQVVSVAAALIPF
LEHDDANRALMGANMQRQAVPTLRADKPLVGTGMEKPIALDSGVAVVAKRGGTVQYVDASRIVIKVNEDETIAGEAGIDI
YNLIKYTRSNQNTCINQIPCVNLGDPINRGEVLADGPSTDLGELALGQNIRVAFMPWNGYNFEDSMLVSERVVQQDRFTT
IHIQELSCVARDTKLGAEEITADIPNVGESALSKLDESGIVYVGAEVKGGDILVGKVTPKGETQLTPEEKLLRAIFGEKA
SDVKDSSLRVPNGTSGTVIDVQVFTRDGVEKDKRALEIEEMQLREAKKDLTEELEILEAGLFARVRNLLISSGADAAQLD
KVDRTKWLEQTIADEEKQNQLEQLAEQYEELRKEFEHKLEVKRKKIIKGDDLAPGVLKVVKVYLAVKRQIQPGDKMAGRH
GNKGVISKINPVEDMPYDENGQPVEIVLNPLGVPSRMNIGQILETHLGLAAKGIGDQINAMLKQKQEVEKLRSYIQKAYD
LLGNGSQKVDLSTFTDEEVLRLAGNLRKGLPVATPVFDGADEAEIKELLKLGGLPTSGQITLYDGRTGEKFERPVTVGYM
YMLKLNHLVDDKMHARSTGSYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVNGRTKMYKNIVS
GNQHMEPGTPESFNVIMKEIRSLGLNIELDEE
>Mature_1312_residues
MDSFDKFIQKDPEGQQGLEAAFRSVFPIVSNNGYTELQYVDYRLEEPEFDVRECQIRGSTYAAGLRVKLRLVSYDKESSS
RAVKDIKENEVYMGEIPLMTDNGTFVINGTERVIVSQLHRSPGVFFDSDKGKTHSSGKVLYNARIIPYRGSWLDFEFDPK
DNLFARIDRRRKLPATIILRALGYTTEEILNLFFDKITFEIAGDKLLMTLVPERLRGETASFDIEANGKVYVERGRRITA
RHIKALEKDNISQVVVPSEYILGKVASKDYVDLESGEIICPANGEISLETLAKLAQAGYTTIETLFTNDLDYGPYISETL
RVDPTYDKISALYEIYRMMRPGEPPTPESSEALFNNLFFSAERYDLSTVGRMKFNRSLAFPEGEGAGILSNEDIIAVMRK
LIDIRNGRGEVDDIDHLGNRRIRSVGEMAENQFRIGLVRVERAVKERLSLGDLDAITPQDLINPKPISAAVKEFFGSSQL
SQFMDQNNPLSEVTHKRRISALGPGGLTRERAGFEVRDVHNTHYGRLCPIETPEGPNIGLINSLSAFARTNDYGFLETPY
RKVVDGQVTEEIEYLSVIDEANYIIAQANSNLDENNRFTDAFVTARGERGESGLYKPEDIHYMDVSTQQVVSVAAALIPF
LEHDDANRALMGANMQRQAVPTLRADKPLVGTGMEKPIALDSGVAVVAKRGGTVQYVDASRIVIKVNEDETIAGEAGIDI
YNLIKYTRSNQNTCINQIPCVNLGDPINRGEVLADGPSTDLGELALGQNIRVAFMPWNGYNFEDSMLVSERVVQQDRFTT
IHIQELSCVARDTKLGAEEITADIPNVGESALSKLDESGIVYVGAEVKGGDILVGKVTPKGETQLTPEEKLLRAIFGEKA
SDVKDSSLRVPNGTSGTVIDVQVFTRDGVEKDKRALEIEEMQLREAKKDLTEELEILEAGLFARVRNLLISSGADAAQLD
KVDRTKWLEQTIADEEKQNQLEQLAEQYEELRKEFEHKLEVKRKKIIKGDDLAPGVLKVVKVYLAVKRQIQPGDKMAGRH
GNKGVISKINPVEDMPYDENGQPVEIVLNPLGVPSRMNIGQILETHLGLAAKGIGDQINAMLKQKQEVEKLRSYIQKAYD
LLGNGSQKVDLSTFTDEEVLRLAGNLRKGLPVATPVFDGADEAEIKELLKLGGLPTSGQITLYDGRTGEKFERPVTVGYM
YMLKLNHLVDDKMHARSTGSYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVNGRTKMYKNIVS
GNQHMEPGTPESFNVIMKEIRSLGLNIELDEE

Specific function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates [H]

COG id: COG0085

COG function: function code K; DNA-directed RNA polymerase, beta subunit/140 kD subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA polymerase beta chain family [H]

Homologues:

Organism=Homo sapiens, GI33469941, Length=263, Percent_Identity=31.1787072243346, Blast_Score=120, Evalue=9e-27,
Organism=Homo sapiens, GI212286172, Length=263, Percent_Identity=31.1787072243346, Blast_Score=120, Evalue=1e-26,
Organism=Homo sapiens, GI238908503, Length=297, Percent_Identity=28.6195286195286, Blast_Score=111, Evalue=5e-24,
Organism=Homo sapiens, GI238908505, Length=297, Percent_Identity=28.6195286195286, Blast_Score=111, Evalue=5e-24,
Organism=Homo sapiens, GI4505941, Length=249, Percent_Identity=31.3253012048193, Blast_Score=109, Evalue=2e-23,
Organism=Escherichia coli, GI1790419, Length=1312, Percent_Identity=82.9268292682927, Blast_Score=2261, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17506623, Length=234, Percent_Identity=32.0512820512821, Blast_Score=116, Evalue=9e-26,
Organism=Caenorhabditis elegans, GI17552304, Length=249, Percent_Identity=31.3253012048193, Blast_Score=109, Evalue=8e-24,
Organism=Caenorhabditis elegans, GI25144348, Length=302, Percent_Identity=27.8145695364238, Blast_Score=99, Evalue=1e-20,
Organism=Saccharomyces cerevisiae, GI6324781, Length=248, Percent_Identity=32.6612903225806, Blast_Score=119, Evalue=3e-27,
Organism=Saccharomyces cerevisiae, GI6324725, Length=250, Percent_Identity=33.2, Blast_Score=118, Evalue=6e-27,
Organism=Saccharomyces cerevisiae, GI6325267, Length=253, Percent_Identity=31.2252964426877, Blast_Score=112, Evalue=3e-25,
Organism=Drosophila melanogaster, GI17136446, Length=262, Percent_Identity=32.4427480916031, Blast_Score=112, Evalue=1e-24,
Organism=Drosophila melanogaster, GI17647877, Length=248, Percent_Identity=31.8548387096774, Blast_Score=110, Evalue=5e-24,
Organism=Drosophila melanogaster, GI17136444, Length=249, Percent_Identity=30.5220883534137, Blast_Score=105, Evalue=2e-22,

Paralogues:

None

Copy number: 4233 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010243
- InterPro:   IPR019462
- InterPro:   IPR015712
- InterPro:   IPR007120
- InterPro:   IPR007121
- InterPro:   IPR007644
- InterPro:   IPR007642
- InterPro:   IPR007645
- InterPro:   IPR007641
- InterPro:   IPR014724 [H]

Pfam domain/function: PF04563 RNA_pol_Rpb2_1; PF04561 RNA_pol_Rpb2_2; PF04565 RNA_pol_Rpb2_3; PF10385 RNA_pol_Rpb2_45; PF00562 RNA_pol_Rpb2_6; PF04560 RNA_pol_Rpb2_7 [H]

EC number: =2.7.7.6 [H]

Molecular weight: Translated: 146091; Mature: 146091

Theoretical pI: Translated: 4.83; Mature: 4.83

Prosite motif: PS01166 RNA_POL_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDSFDKFIQKDPEGQQGLEAAFRSVFPIVSNNGYTELQYVDYRLEEPEFDVRECQIRGST
CCCHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCEEEEEEEEEECCCCCCCCHHEEECCCE
YAAGLRVKLRLVSYDKESSSRAVKDIKENEVYMGEIPLMTDNGTFVINGTERVIVSQLHR
EEECEEEEEEEEECCCCCHHHHHHHHHCCCEEEECEEEEECCCEEEECCCHHHHHHHHHC
SPGVFFDSDKGKTHSSGKVLYNARIIPYRGSWLDFEFDPKDNLFARIDRRRKLPATIILR
CCCCEEECCCCCCCCCCEEEEEEEEEEECCCEEEEEECCCCCHHHHHHHHCCCCHHHHHH
ALGYTTEEILNLFFDKITFEIAGDKLLMTLVPERLRGETASFDIEANGKVYVERGRRITA
HHCCCHHHHHHHHHHHHEEEECCCEEEEECCCHHHCCCCCEEEEECCCEEEEECCCEEHH
RHIKALEKDNISQVVVPSEYILGKVASKDYVDLESGEIICPANGEISLETLAKLAQAGYT
HHHHHHHHCCCCEEECCHHHHHHHHCCCCCEECCCCCEEECCCCCEEHHHHHHHHHCCCH
TIETLFTNDLDYGPYISETLRVDPTYDKISALYEIYRMMRPGEPPTPESSEALFNNLFFS
HHHHHHCCCCCCCCCCHHHEECCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHC
AERYDLSTVGRMKFNRSLAFPEGEGAGILSNEDIIAVMRKLIDIRNGRGEVDDIDHLGNR
CCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHCCH
RIRSVGEMAENQFRIGLVRVERAVKERLSLGDLDAITPQDLINPKPISAAVKEFFGSSQL
HHHHHHHHHHCCCEEHHHHHHHHHHHHCCCCCCCCCCHHHCCCCCCHHHHHHHHHCHHHH
SQFMDQNNPLSEVTHKRRISALGPGGLTRERAGFEVRDVHNTHYGRLCPIETPEGPNIGL
HHHHHCCCCHHHHHHHHHHHCCCCCCCCHHHCCCEEEECCCCCCCCCCCCCCCCCCCCCH
INSLSAFARTNDYGFLETPYRKVVDGQVTEEIEYLSVIDEANYIIAQANSNLDENNRFTD
HHHHHHHHHCCCCCCCCCCHHHHHCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCEEE
AFVTARGERGESGLYKPEDIHYMDVSTQQVVSVAAALIPFLEHDDANRALMGANMQRQAV
EEEEECCCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHCCCCCCEEECCCCHHHCC
PTLRADKPLVGTGMEKPIALDSGVAVVAKRGGTVQYVDASRIVIKVNEDETIAGEAGIDI
CCCCCCCCCCCCCCCCCEEECCCCEEEEECCCEEEEEECCEEEEEECCCCEECCCCCCHH
YNLIKYTRSNQNTCINQIPCVNLGDPINRGEVLADGPSTDLGELALGQNIRVAFMPWNGY
HHHHHHHCCCCCCHHHCCCCCCCCCCCCCCCEEECCCCCCHHHHHCCCCEEEEEEECCCC
NFEDSMLVSERVVQQDRFTTIHIQELSCVARDTKLGAEEITADIPNVGESALSKLDESGI
CCCHHHHHHHHHHHHCCCEEEEEEHHHHHHHHHCCCHHHHHCCCCCCCHHHHHHCCCCCE
VYVGAEVKGGDILVGKVTPKGETQLTPEEKLLRAIFGEKASDVKDSSLRVPNGTSGTVID
EEEEEEECCCCEEEEECCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCEECCCCCCCCEEE
VQVFTRDGVEKDKRALEIEEMQLREAKKDLTEELEILEAGLFARVRNLLISSGADAAQLD
EEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
KVDRTKWLEQTIADEEKQNQLEQLAEQYEELRKEFEHKLEVKRKKIIKGDDLAPGVLKVV
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
KVYLAVKRQIQPGDKMAGRHGNKGVISKINPVEDMPYDENGQPVEIVLNPLGVPSRMNIG
HHHHHHHHHCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCHH
QILETHLGLAAKGIGDQINAMLKQKQEVEKLRSYIQKAYDLLGNGSQKVDLSTFTDEEVL
HHHHHHHCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHH
RLAGNLRKGLPVATPVFDGADEAEIKELLKLGGLPTSGQITLYDGRTGEKFERPVTVGYM
HHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCEEEEEECCCCCHHCCCEEHHHH
YMLKLNHLVDDKMHARSTGSYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEM
EEHHHHHHHCCHHHHCCCCCEEEEECCCCCCCCCCCCCCCCCEEEEEEECCCHHHHHHHH
LTVKSDDVNGRTKMYKNIVSGNQHMEPGTPESFNVIMKEIRSLGLNIELDEE
HHHCCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCEEECCC
>Mature Secondary Structure
MDSFDKFIQKDPEGQQGLEAAFRSVFPIVSNNGYTELQYVDYRLEEPEFDVRECQIRGST
CCCHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCEEEEEEEEEECCCCCCCCHHEEECCCE
YAAGLRVKLRLVSYDKESSSRAVKDIKENEVYMGEIPLMTDNGTFVINGTERVIVSQLHR
EEECEEEEEEEEECCCCCHHHHHHHHHCCCEEEECEEEEECCCEEEECCCHHHHHHHHHC
SPGVFFDSDKGKTHSSGKVLYNARIIPYRGSWLDFEFDPKDNLFARIDRRRKLPATIILR
CCCCEEECCCCCCCCCCEEEEEEEEEEECCCEEEEEECCCCCHHHHHHHHCCCCHHHHHH
ALGYTTEEILNLFFDKITFEIAGDKLLMTLVPERLRGETASFDIEANGKVYVERGRRITA
HHCCCHHHHHHHHHHHHEEEECCCEEEEECCCHHHCCCCCEEEEECCCEEEEECCCEEHH
RHIKALEKDNISQVVVPSEYILGKVASKDYVDLESGEIICPANGEISLETLAKLAQAGYT
HHHHHHHHCCCCEEECCHHHHHHHHCCCCCEECCCCCEEECCCCCEEHHHHHHHHHCCCH
TIETLFTNDLDYGPYISETLRVDPTYDKISALYEIYRMMRPGEPPTPESSEALFNNLFFS
HHHHHHCCCCCCCCCCHHHEECCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHC
AERYDLSTVGRMKFNRSLAFPEGEGAGILSNEDIIAVMRKLIDIRNGRGEVDDIDHLGNR
CCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHCCH
RIRSVGEMAENQFRIGLVRVERAVKERLSLGDLDAITPQDLINPKPISAAVKEFFGSSQL
HHHHHHHHHHCCCEEHHHHHHHHHHHHCCCCCCCCCCHHHCCCCCCHHHHHHHHHCHHHH
SQFMDQNNPLSEVTHKRRISALGPGGLTRERAGFEVRDVHNTHYGRLCPIETPEGPNIGL
HHHHHCCCCHHHHHHHHHHHCCCCCCCCHHHCCCEEEECCCCCCCCCCCCCCCCCCCCCH
INSLSAFARTNDYGFLETPYRKVVDGQVTEEIEYLSVIDEANYIIAQANSNLDENNRFTD
HHHHHHHHHCCCCCCCCCCHHHHHCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCEEE
AFVTARGERGESGLYKPEDIHYMDVSTQQVVSVAAALIPFLEHDDANRALMGANMQRQAV
EEEEECCCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHCCCCCCEEECCCCHHHCC
PTLRADKPLVGTGMEKPIALDSGVAVVAKRGGTVQYVDASRIVIKVNEDETIAGEAGIDI
CCCCCCCCCCCCCCCCCEEECCCCEEEEECCCEEEEEECCEEEEEECCCCEECCCCCCHH
YNLIKYTRSNQNTCINQIPCVNLGDPINRGEVLADGPSTDLGELALGQNIRVAFMPWNGY
HHHHHHHCCCCCCHHHCCCCCCCCCCCCCCCEEECCCCCCHHHHHCCCCEEEEEEECCCC
NFEDSMLVSERVVQQDRFTTIHIQELSCVARDTKLGAEEITADIPNVGESALSKLDESGI
CCCHHHHHHHHHHHHCCCEEEEEEHHHHHHHHHCCCHHHHHCCCCCCCHHHHHHCCCCCE
VYVGAEVKGGDILVGKVTPKGETQLTPEEKLLRAIFGEKASDVKDSSLRVPNGTSGTVID
EEEEEEECCCCEEEEECCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCEECCCCCCCCEEE
VQVFTRDGVEKDKRALEIEEMQLREAKKDLTEELEILEAGLFARVRNLLISSGADAAQLD
EEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
KVDRTKWLEQTIADEEKQNQLEQLAEQYEELRKEFEHKLEVKRKKIIKGDDLAPGVLKVV
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
KVYLAVKRQIQPGDKMAGRHGNKGVISKINPVEDMPYDENGQPVEIVLNPLGVPSRMNIG
HHHHHHHHHCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCHH
QILETHLGLAAKGIGDQINAMLKQKQEVEKLRSYIQKAYDLLGNGSQKVDLSTFTDEEVL
HHHHHHHCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHH
RLAGNLRKGLPVATPVFDGADEAEIKELLKLGGLPTSGQITLYDGRTGEKFERPVTVGYM
HHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCEEEEEECCCCCHHCCCEEHHHH
YMLKLNHLVDDKMHARSTGSYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEM
EEHHHHHHHCCHHHHCCCCCEEEEECCCCCCCCCCCCCCCCCEEEEEEECCCHHHHHHHH
LTVKSDDVNGRTKMYKNIVSGNQHMEPGTPESFNVIMKEIRSLGLNIELDEE
HHHCCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA