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The map label for this gene is yggW [C]

Identifier: 148827660

GI number: 148827660

Start: 1011470

End: 1012621

Strand: Direct

Name: yggW [C]

Synonym: CGSHiGG_05555

Alternate gene names: 148827660

Gene position: 1011470-1012621 (Clockwise)

Preceding gene: 148827659

Following gene: 148827661

Centisome position: 53.6

GC content: 38.72

Gene sequence:

>1152_bases
ATGCTAAAACTTCCCCCACTTTCCCTTTATATACACATTCCATGGTGCGTTCAAAAATGCCCTTATTGTGATTTTAATTC
GCACGCACAAAAAAGCGATATACCAGAACAAGACTATATTTATCATCTTCTGCAAGATTTGCAGGCTGATTTGCAACGCT
TTAAAGATTCTATTCAACAACGAAAACTCCATTCAATTTTTATTGGTGGCGGTACACCAAGTTTGTTCTCGGCAGAAAGC
ATTGCGTATCTCTTAAAAGAAATAAAAAAACAGATTGATTTTGAAGATAATATTGAAATCACATTAGAGGCTAATCCCGG
TACGGTAGAAGCTGAACGCTTTAAAGGTTATGTTTCAGCAGGCATTACGCGAATTTCTATGGGAATTCAAAGTTTCAATG
ATGATAAATTACAGCGTCTTGGGCGAATTCATAATGCAGCAGAGGCAAAAAGTGCGGTCAATTTAGCGAAAGTTTCTGGG
CTAAAAAGTTTCAATTTAGATTTAATGCACGGTTTGCCGAACCAAACGTTGGAAGAAGCCTTAGATGATCTTCGTCAAGC
AATTGAGCTATCTCCTCCCCATATTTCTTGGTATCAGCTGACTATTGAACCAAATACGATGTTTGCTTATCGCCCACCTA
AATTACCAGATGATGACGCACTTTGGGACATTTTTGAGCAAGGTCACCAACTTTTAACGATGGCAGGCTACCAGCAATAT
GAAACCTCAGCTTACGCAAAAGCGGGTGTTCAATGTAAACATAATTTGAATTATTGGCGATTTGGGGATTATTTAGCCAT
TGGCTGTGGCGCACACGGGAAATTGACGTTTCCGACTGGCGAGATTACTCGCTTTTCTAAAACCAAGCACCCGAAAGGTT
ATTTGCGTGGCGAATATCTTTACGAAGAAAAAAACGTGCCAAAAATTGACCGCCCTTTTGAGTTTTTTATGAATCGCTTT
CGTTTGTTAGAAGCGGTACCCAAACAAGAATTTGAAGATTACACAGGCTTGTCGCAAAGTGCGGTGAAAAATCAAATTGA
TTTTGCCATTCAACAAAACTATATTGTGGAAAACGCTGATTCTTGGCAAATCACTGAACACGGCAAGTTATTTCTCAATG
AACTTTTGGAATTATTTTTAACGGAAGAATAG

Upstream 100 bases:

>100_bases
CTTGTGAAAACAAGCCCTTTATTGATTTTAGAGATGATAATTTCATCTTTACACAAGGTTAATTTATACTTTTCCAAATT
GAAAACTTGTTAATAACACA

Downstream 100 bases:

>100_bases
CCTAATCGTGAAATAACCTAGTCGTGAAATAACATTGCTTGAGAAAAACGCCTGTTAAAAATTACACTTGTTTATTAAAT
ACTCTCGTAATAAAGTAACA

Product: coproporphyrinogen III oxidase

Products: Protoporphyrinogen IX; CO2; H2O

Alternate protein names: NA

Number of amino acids: Translated: 383; Mature: 383

Protein sequence:

>383_residues
MLKLPPLSLYIHIPWCVQKCPYCDFNSHAQKSDIPEQDYIYHLLQDLQADLQRFKDSIQQRKLHSIFIGGGTPSLFSAES
IAYLLKEIKKQIDFEDNIEITLEANPGTVEAERFKGYVSAGITRISMGIQSFNDDKLQRLGRIHNAAEAKSAVNLAKVSG
LKSFNLDLMHGLPNQTLEEALDDLRQAIELSPPHISWYQLTIEPNTMFAYRPPKLPDDDALWDIFEQGHQLLTMAGYQQY
ETSAYAKAGVQCKHNLNYWRFGDYLAIGCGAHGKLTFPTGEITRFSKTKHPKGYLRGEYLYEEKNVPKIDRPFEFFMNRF
RLLEAVPKQEFEDYTGLSQSAVKNQIDFAIQQNYIVENADSWQITEHGKLFLNELLELFLTEE

Sequences:

>Translated_383_residues
MLKLPPLSLYIHIPWCVQKCPYCDFNSHAQKSDIPEQDYIYHLLQDLQADLQRFKDSIQQRKLHSIFIGGGTPSLFSAES
IAYLLKEIKKQIDFEDNIEITLEANPGTVEAERFKGYVSAGITRISMGIQSFNDDKLQRLGRIHNAAEAKSAVNLAKVSG
LKSFNLDLMHGLPNQTLEEALDDLRQAIELSPPHISWYQLTIEPNTMFAYRPPKLPDDDALWDIFEQGHQLLTMAGYQQY
ETSAYAKAGVQCKHNLNYWRFGDYLAIGCGAHGKLTFPTGEITRFSKTKHPKGYLRGEYLYEEKNVPKIDRPFEFFMNRF
RLLEAVPKQEFEDYTGLSQSAVKNQIDFAIQQNYIVENADSWQITEHGKLFLNELLELFLTEE
>Mature_383_residues
MLKLPPLSLYIHIPWCVQKCPYCDFNSHAQKSDIPEQDYIYHLLQDLQADLQRFKDSIQQRKLHSIFIGGGTPSLFSAES
IAYLLKEIKKQIDFEDNIEITLEANPGTVEAERFKGYVSAGITRISMGIQSFNDDKLQRLGRIHNAAEAKSAVNLAKVSG
LKSFNLDLMHGLPNQTLEEALDDLRQAIELSPPHISWYQLTIEPNTMFAYRPPKLPDDDALWDIFEQGHQLLTMAGYQQY
ETSAYAKAGVQCKHNLNYWRFGDYLAIGCGAHGKLTFPTGEITRFSKTKHPKGYLRGEYLYEEKNVPKIDRPFEFFMNRF
RLLEAVPKQEFEDYTGLSQSAVKNQIDFAIQQNYIVENADSWQITEHGKLFLNELLELFLTEE

Specific function: Unknown

COG id: COG0635

COG function: function code H; Coproporphyrinogen III oxidase and related Fe-S oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anaerobic coproporphyrinogen-III oxidase family [H]

Homologues:

Organism=Homo sapiens, GI8922911, Length=277, Percent_Identity=33.2129963898917, Blast_Score=174, Evalue=1e-43,
Organism=Escherichia coli, GI1789325, Length=382, Percent_Identity=66.7539267015707, Blast_Score=553, Evalue=1e-158,
Organism=Escherichia coli, GI87082341, Length=236, Percent_Identity=30.0847457627119, Blast_Score=115, Evalue=6e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006638
- InterPro:   IPR004559
- InterPro:   IPR010723
- InterPro:   IPR007197 [H]

Pfam domain/function: PF06969 HemN_C; PF04055 Radical_SAM [H]

EC number: 1.3.3.3

Molecular weight: Translated: 44043; Mature: 44043

Theoretical pI: Translated: 5.60; Mature: 5.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKLPPLSLYIHIPWCVQKCPYCDFNSHAQKSDIPEQDYIYHLLQDLQADLQRFKDSIQQ
CCCCCCEEEEEECCHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
RKLHSIFIGGGTPSLFSAESIAYLLKEIKKQIDFEDNIEITLEANPGTVEAERFKGYVSA
HHHHEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCHHHHHHHHHH
GITRISMGIQSFNDDKLQRLGRIHNAAEAKSAVNLAKVSGLKSFNLDLMHGLPNQTLEEA
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCCHHHHHH
LDDLRQAIELSPPHISWYQLTIEPNTMFAYRPPKLPDDDALWDIFEQGHQLLTMAGYQQY
HHHHHHHHHCCCCCCEEEEEEECCCEEEEECCCCCCCCHHHHHHHHCCHHEEHHHCCHHH
ETSAYAKAGVQCKHNLNYWRFGDYLAIGCGAHGKLTFPTGEITRFSKTKHPKGYLRGEYL
HHHHHHHCCCCEECCCCEEEECCEEEEECCCCCEEECCCCCCHHCCCCCCCCCCCCCCEE
YEEKNVPKIDRPFEFFMNRFRLLEAVPKQEFEDYTGLSQSAVKNQIDFAIQQNYIVENAD
ECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCEEEECCC
SWQITEHGKLFLNELLELFLTEE
CCEECHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLKLPPLSLYIHIPWCVQKCPYCDFNSHAQKSDIPEQDYIYHLLQDLQADLQRFKDSIQQ
CCCCCCEEEEEECCHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
RKLHSIFIGGGTPSLFSAESIAYLLKEIKKQIDFEDNIEITLEANPGTVEAERFKGYVSA
HHHHEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCHHHHHHHHHH
GITRISMGIQSFNDDKLQRLGRIHNAAEAKSAVNLAKVSGLKSFNLDLMHGLPNQTLEEA
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCCHHHHHH
LDDLRQAIELSPPHISWYQLTIEPNTMFAYRPPKLPDDDALWDIFEQGHQLLTMAGYQQY
HHHHHHHHHCCCCCCEEEEEEECCCEEEEECCCCCCCCHHHHHHHHCCHHEEHHHCCHHH
ETSAYAKAGVQCKHNLNYWRFGDYLAIGCGAHGKLTFPTGEITRFSKTKHPKGYLRGEYL
HHHHHHHCCCCEECCCCEEEECCEEEEECCCCCEEECCCCCCHHCCCCCCCCCCCCCCEE
YEEKNVPKIDRPFEFFMNRFRLLEAVPKQEFEDYTGLSQSAVKNQIDFAIQQNYIVENAD
ECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCEEEECCC
SWQITEHGKLFLNELLELFLTEE
CCEECHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Coproporphyrinogen III; O2; H+

Specific reaction: coproporphyrinogen-III + O2 + 2 H+ = protoporphyrinogen-IX + 2 CO2 + 2 H2O

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]