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The map label for this gene is xseA [H]

Identifier: 148827599

GI number: 148827599

Start: 942318

End: 943646

Strand: Direct

Name: xseA [H]

Synonym: CGSHiGG_05160

Alternate gene names: 148827599

Gene position: 942318-943646 (Clockwise)

Preceding gene: 148827598

Following gene: 148827600

Centisome position: 49.93

GC content: 41.23

Gene sequence:

>1329_bases
TTGAATAATATGTCAGACAATATTTATTCCGTCTCTCAACTGAATTCTGCCGCGCGTCAGATGTTGGAGGGGCATTTTTC
CCAAATTTGGCTAACGGGGGAAATTTCCAATTTTACCCAACCTGTGTCTGGGCATTGGTATTTAACGCTGAAAGATGAAA
ATGCACAGGTGCGTTGTGCAATGTTTCGTATGAAAAATTTGCGTGTTGCTTTTCGTCCACAAAATGGAATGCAAGTGCTT
GTGCGTGCCAATGTGAGTTTATATGAGCCTCGTGGCGATTATCAACTTATTATTGATTCTATGCACCCAGCTGGCGAGGG
ATTATTGCAACAGCAATTTGAAGCGTTAAAAATGAAGTTGGCTACGGAGGGATTGTTTGCTCAAAATCTCAAGAAAAATC
TACCGCACTTTAGTAAAGCCGTTGGGATTATAACTTCTTCTACAGGTGCGGCATTGCAAGATATTTTGCATATTTTGGCA
CGCCGTGATCCAAGTTTAAAAGTTGTTATTTATCCCACTGCAGTTCAAGGCAAAGAGGCGACAGCAGAAATTGTGCAAAT
GATTGAACTTGCTAATGCGCGACAAGAAGTAGATGTATTAATTGTTGGGCGTGGTGGTGGTTCATTAGAAGATCTTTGGT
GTTTTAATGAAGAAGAAGTGGCGCGAGCGATTTTTCGTTCAACCTTACCCATTATCAGTGCGGTGGGACACGAAACAGAT
GTGACGATTGCCGATTTTGTTGCAGATCTTCGTGCGCCAACCCCTTCTGCAGCGGCAGAGTTAGTTAGTCGTAATCAAGA
TGAATTATTGCAACAACTTCGCCATCAACAGCAACGTTTAGATATGGCATTTGATCGTTTATTTACGAGAAAAAGCCAGC
GTTTGAAACAGCTAACCTTAAGATTACACAATCAACATCCACAGAATCAGTTACGCGTTCAACAAGCAAAAAATGCACAG
CTTACGCATCGCTTGCAACTTGCAATATTGCGTCAGTTTGAAAATACACAACAAAAATTCACCGCACTTTCTGTTCGTTT
AAAACAAAATCCATTGCCATATCGCATACAACGTCATCAACAGCATTTAGAACAACTTCAAGTGCGGTTAAATTTTTGCG
TAAATCGCCAAGTGACGGAACGTCAAAATAAACTGGCAACATTATGCGGAAAACTGGATGGCTTAAGCCCGTTGAAAGTC
TTGGCGAGAGGTTATTCCATTGCGGAAAATCCGCAAGGTAAAGCCATTGTTAGCGTGAAAGATGTCAATCAAGGGGACTT
CATTACAACTCAAGTGGCTGATGGAAAAATTGTGAGTAAGGTTTTGTAA

Upstream 100 bases:

>100_bases
TTTCTATCTAATTTAGTGAATGAAACCGAAGATCCCGAAACTTCAATGGATTTGTTGTTGGATTCCATTTGTAACTGGGT
TGATGATGGGTGGGCGTTAA

Downstream 100 bases:

>100_bases
GATGCTTATTTTGTAAAAATGGAGTGAAATACTGTTTCACTTACTTCTAAAAAAGAATGCTATGACTGTTGAATAAATAA
TCATGGCATTTTGTTTTTTT

Product: exodeoxyribonuclease VII large subunit

Products: NA

Alternate protein names: Exodeoxyribonuclease VII large subunit; Exonuclease VII large subunit [H]

Number of amino acids: Translated: 442; Mature: 442

Protein sequence:

>442_residues
MNNMSDNIYSVSQLNSAARQMLEGHFSQIWLTGEISNFTQPVSGHWYLTLKDENAQVRCAMFRMKNLRVAFRPQNGMQVL
VRANVSLYEPRGDYQLIIDSMHPAGEGLLQQQFEALKMKLATEGLFAQNLKKNLPHFSKAVGIITSSTGAALQDILHILA
RRDPSLKVVIYPTAVQGKEATAEIVQMIELANARQEVDVLIVGRGGGSLEDLWCFNEEEVARAIFRSTLPIISAVGHETD
VTIADFVADLRAPTPSAAAELVSRNQDELLQQLRHQQQRLDMAFDRLFTRKSQRLKQLTLRLHNQHPQNQLRVQQAKNAQ
LTHRLQLAILRQFENTQQKFTALSVRLKQNPLPYRIQRHQQHLEQLQVRLNFCVNRQVTERQNKLATLCGKLDGLSPLKV
LARGYSIAENPQGKAIVSVKDVNQGDFITTQVADGKIVSKVL

Sequences:

>Translated_442_residues
MNNMSDNIYSVSQLNSAARQMLEGHFSQIWLTGEISNFTQPVSGHWYLTLKDENAQVRCAMFRMKNLRVAFRPQNGMQVL
VRANVSLYEPRGDYQLIIDSMHPAGEGLLQQQFEALKMKLATEGLFAQNLKKNLPHFSKAVGIITSSTGAALQDILHILA
RRDPSLKVVIYPTAVQGKEATAEIVQMIELANARQEVDVLIVGRGGGSLEDLWCFNEEEVARAIFRSTLPIISAVGHETD
VTIADFVADLRAPTPSAAAELVSRNQDELLQQLRHQQQRLDMAFDRLFTRKSQRLKQLTLRLHNQHPQNQLRVQQAKNAQ
LTHRLQLAILRQFENTQQKFTALSVRLKQNPLPYRIQRHQQHLEQLQVRLNFCVNRQVTERQNKLATLCGKLDGLSPLKV
LARGYSIAENPQGKAIVSVKDVNQGDFITTQVADGKIVSKVL
>Mature_442_residues
MNNMSDNIYSVSQLNSAARQMLEGHFSQIWLTGEISNFTQPVSGHWYLTLKDENAQVRCAMFRMKNLRVAFRPQNGMQVL
VRANVSLYEPRGDYQLIIDSMHPAGEGLLQQQFEALKMKLATEGLFAQNLKKNLPHFSKAVGIITSSTGAALQDILHILA
RRDPSLKVVIYPTAVQGKEATAEIVQMIELANARQEVDVLIVGRGGGSLEDLWCFNEEEVARAIFRSTLPIISAVGHETD
VTIADFVADLRAPTPSAAAELVSRNQDELLQQLRHQQQRLDMAFDRLFTRKSQRLKQLTLRLHNQHPQNQLRVQQAKNAQ
LTHRLQLAILRQFENTQQKFTALSVRLKQNPLPYRIQRHQQHLEQLQVRLNFCVNRQVTERQNKLATLCGKLDGLSPLKV
LARGYSIAENPQGKAIVSVKDVNQGDFITTQVADGKIVSKVL

Specific function: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides [H]

COG id: COG1570

COG function: function code L; Exonuclease VII, large subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xseA family [H]

Homologues:

Organism=Escherichia coli, GI1788856, Length=442, Percent_Identity=56.7873303167421, Blast_Score=496, Evalue=1e-141,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003753
- InterPro:   IPR020579
- InterPro:   IPR004365 [H]

Pfam domain/function: PF02601 Exonuc_VII_L; PF01336 tRNA_anti [H]

EC number: =3.1.11.6 [H]

Molecular weight: Translated: 49906; Mature: 49906

Theoretical pI: Translated: 10.10; Mature: 10.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNMSDNIYSVSQLNSAARQMLEGHFSQIWLTGEISNFTQPVSGHWYLTLKDENAQVRCA
CCCCCCCHHHHHHHHHHHHHHHHCHHHEEEEEEECCCCCCCCCCEEEEEEECCCCEEEHH
MFRMKNLRVAFRPQNGMQVLVRANVSLYEPRGDYQLIIDSMHPAGEGLLQQQFEALKMKL
EEHHHCCEEEEECCCCCEEEEEECCEEECCCCCEEEEEECCCCCCCHHHHHHHHHHHHHH
ATEGLFAQNLKKNLPHFSKAVGIITSSTGAALQDILHILARRDPSLKVVIYPTAVQGKEA
HHHHHHHHHHHHCCCHHHHHHHEEECCCCHHHHHHHHHHHCCCCCEEEEEEECCCCCCHH
TAEIVQMIELANARQEVDVLIVGRGGGSLEDLWCFNEEEVARAIFRSTLPIISAVGHETD
HHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCC
VTIADFVADLRAPTPSAAAELVSRNQDELLQQLRHQQQRLDMAFDRLFTRKSQRLKQLTL
CHHHHHHHHHCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RLHNQHPQNQLRVQQAKNAQLTHRLQLAILRQFENTQQKFTALSVRLKQNPLPYRIQRHQ
HHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCHHHHHHH
QHLEQLQVRLNFCVNRQVTERQNKLATLCGKLDGLSPLKVLARGYSIAENPQGKAIVSVK
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCCCCEEEEEE
DVNQGDFITTQVADGKIVSKVL
ECCCCCEEEEEECCCHHHHHCC
>Mature Secondary Structure
MNNMSDNIYSVSQLNSAARQMLEGHFSQIWLTGEISNFTQPVSGHWYLTLKDENAQVRCA
CCCCCCCHHHHHHHHHHHHHHHHCHHHEEEEEEECCCCCCCCCCEEEEEEECCCCEEEHH
MFRMKNLRVAFRPQNGMQVLVRANVSLYEPRGDYQLIIDSMHPAGEGLLQQQFEALKMKL
EEHHHCCEEEEECCCCCEEEEEECCEEECCCCCEEEEEECCCCCCCHHHHHHHHHHHHHH
ATEGLFAQNLKKNLPHFSKAVGIITSSTGAALQDILHILARRDPSLKVVIYPTAVQGKEA
HHHHHHHHHHHHCCCHHHHHHHEEECCCCHHHHHHHHHHHCCCCCEEEEEEECCCCCCHH
TAEIVQMIELANARQEVDVLIVGRGGGSLEDLWCFNEEEVARAIFRSTLPIISAVGHETD
HHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCC
VTIADFVADLRAPTPSAAAELVSRNQDELLQQLRHQQQRLDMAFDRLFTRKSQRLKQLTL
CHHHHHHHHHCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RLHNQHPQNQLRVQQAKNAQLTHRLQLAILRQFENTQQKFTALSVRLKQNPLPYRIQRHQ
HHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCHHHHHHH
QHLEQLQVRLNFCVNRQVTERQNKLATLCGKLDGLSPLKVLARGYSIAENPQGKAIVSVK
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCCCCEEEEEE
DVNQGDFITTQVADGKIVSKVL
ECCCCCEEEEEECCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA