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The map label for this gene is xerD [H]

Identifier: 148827463

GI number: 148827463

Start: 821437

End: 822330

Strand: Direct

Name: xerD [H]

Synonym: CGSHiGG_04360

Alternate gene names: 148827463

Gene position: 821437-822330 (Clockwise)

Preceding gene: 148827462

Following gene: 148827464

Centisome position: 43.53

GC content: 42.06

Gene sequence:

>894_bases
ATGAAAAATCTTGCACTTATTGATTTGTTCCTTAACGAATATTGGATTGAAAAAGGGCTTTCAGAAAATACCGTTCAATC
TTATCGTTTGGATTTAACCGCACTTTGTGATTGGTTGGATAAAAACGACTTGTCTTTGGAAACTTTAGATGCTGTTCATT
TGCAAGGTTTTCTGGGTGAACGTCTAGAGAAAGGTTACAAAGCCACGAGCACTGCGCGAATGTTAAGTGCAATACGTAAA
CTTTTCCAATATTTATATCGGGAAAAATATCGAGTGGATGATCCAAGTGCGGTGCTAAGTTCGCCTAAATTACCCAGTCG
CTTGCCAAAATATTTAACCGAGCAACAAGTGTCTGATTTGCTCAATACGCCAGATGTGGAAGTGCCTTTGGAGTTGCGTG
ATAAAGCAATGTTAGAGTTGCTTTATGCAACGGGGCTTCGTGTCACGGAGTTAGTTTCGCTTACGATTGAAAACATGAGT
GTGCAACAAGGCGTGGTGCGAGTGATTGGTAAAGGGAACAAAGAGCGTATTGTGCCAATGGGGGAAGAAGCTGCTTATTG
GGTTCGTCAATTTATGCTGTATGGTCGCCCTGTTCTCTTAAATGGGCAGAGTTCTGATGTTGTGTTTCCAAGTCAGCGCA
CACAGCAAATGACTCGTCAAACTTTCTGGCATCGTGTAAAACATTATGCCATTCTCGCAGATATTGATGCGGATGCACTT
TCCCCTCACGTTCTCCGCCATGCTTTTGCCACCCATTTAGTGAATCACGGTGCGGATTTACGCGTGGTGCAAATGTTGTT
GGGTCATACAGATTTATCTACAACACAGATTTATACTCACGTGGCAAAAGAAAGATTGAAACGATTGCATGAAAGATTTC
ATCCTAGAGGATAA

Upstream 100 bases:

>100_bases
TATTGCAGCTGCTGCATTTTTTGTGATTCCACGTAAGTTAAATGCCTTTTTGATTGTTCAGCATAAATAGGACGTATCGC
TTTCCTTGTAGAAAAGTAAT

Downstream 100 bases:

>100_bases
TTTCGGGGTAAATTTTTATAGTTTTAAAGATTGATTGTGGATTTCTTATTGATTAATTAATTTGACACGCATCACAAATT
TTGAATAAAAAATTAGACAG

Product: site-specific tyrosine recombinase XerD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 297; Mature: 297

Protein sequence:

>297_residues
MKNLALIDLFLNEYWIEKGLSENTVQSYRLDLTALCDWLDKNDLSLETLDAVHLQGFLGERLEKGYKATSTARMLSAIRK
LFQYLYREKYRVDDPSAVLSSPKLPSRLPKYLTEQQVSDLLNTPDVEVPLELRDKAMLELLYATGLRVTELVSLTIENMS
VQQGVVRVIGKGNKERIVPMGEEAAYWVRQFMLYGRPVLLNGQSSDVVFPSQRTQQMTRQTFWHRVKHYAILADIDADAL
SPHVLRHAFATHLVNHGADLRVVQMLLGHTDLSTTQIYTHVAKERLKRLHERFHPRG

Sequences:

>Translated_297_residues
MKNLALIDLFLNEYWIEKGLSENTVQSYRLDLTALCDWLDKNDLSLETLDAVHLQGFLGERLEKGYKATSTARMLSAIRK
LFQYLYREKYRVDDPSAVLSSPKLPSRLPKYLTEQQVSDLLNTPDVEVPLELRDKAMLELLYATGLRVTELVSLTIENMS
VQQGVVRVIGKGNKERIVPMGEEAAYWVRQFMLYGRPVLLNGQSSDVVFPSQRTQQMTRQTFWHRVKHYAILADIDADAL
SPHVLRHAFATHLVNHGADLRVVQMLLGHTDLSTTQIYTHVAKERLKRLHERFHPRG
>Mature_297_residues
MKNLALIDLFLNEYWIEKGLSENTVQSYRLDLTALCDWLDKNDLSLETLDAVHLQGFLGERLEKGYKATSTARMLSAIRK
LFQYLYREKYRVDDPSAVLSSPKLPSRLPKYLTEQQVSDLLNTPDVEVPLELRDKAMLELLYATGLRVTELVSLTIENMS
VQQGVVRVIGKGNKERIVPMGEEAAYWVRQFMLYGRPVLLNGQSSDVVFPSQRTQQMTRQTFWHRVKHYAILADIDADAL
SPHVLRHAFATHLVNHGADLRVVQMLLGHTDLSTTQIYTHVAKERLKRLHERFHPRG

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG4974

COG function: function code L; Site-specific recombinase XerD

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789261, Length=296, Percent_Identity=68.2432432432432, Blast_Score=427, Evalue=1e-121,
Organism=Escherichia coli, GI1790244, Length=292, Percent_Identity=35.2739726027397, Blast_Score=178, Evalue=4e-46,
Organism=Escherichia coli, GI1790768, Length=188, Percent_Identity=26.5957446808511, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011932 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 34156; Mature: 34156

Theoretical pI: Translated: 8.82; Mature: 8.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNLALIDLFLNEYWIEKGLSENTVQSYRLDLTALCDWLDKNDLSLETLDAVHLQGFLGE
CCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
RLEKGYKATSTARMLSAIRKLFQYLYREKYRVDDPSAVLSSPKLPSRLPKYLTEQQVSDL
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHH
LNTPDVEVPLELRDKAMLELLYATGLRVTELVSLTIENMSVQQGVVRVIGKGNKERIVPM
HCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
GEEAAYWVRQFMLYGRPVLLNGQSSDVVFPSQRTQQMTRQTFWHRVKHYAILADIDADAL
CHHHHHHHHHHHHHCCCEEECCCCCCEECCCHHHHHHHHHHHHHHHHHHHEEEECCHHHC
SPHVLRHAFATHLVNHGADLRVVQMLLGHTDLSTTQIYTHVAKERLKRLHERFHPRG
CHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKNLALIDLFLNEYWIEKGLSENTVQSYRLDLTALCDWLDKNDLSLETLDAVHLQGFLGE
CCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
RLEKGYKATSTARMLSAIRKLFQYLYREKYRVDDPSAVLSSPKLPSRLPKYLTEQQVSDL
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHH
LNTPDVEVPLELRDKAMLELLYATGLRVTELVSLTIENMSVQQGVVRVIGKGNKERIVPM
HCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
GEEAAYWVRQFMLYGRPVLLNGQSSDVVFPSQRTQQMTRQTFWHRVKHYAILADIDADAL
CHHHHHHHHHHHHHCCCEEECCCCCCEECCCHHHHHHHHHHHHHHHHHHHEEEECCHHHC
SPHVLRHAFATHLVNHGADLRVVQMLLGHTDLSTTQIYTHVAKERLKRLHERFHPRG
CHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]