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The map label for this gene is metJ [H]

Identifier: 148827448

GI number: 148827448

Start: 807257

End: 807466

Strand: Reverse

Name: metJ [H]

Synonym: CGSHiGG_04285

Alternate gene names: 148827448

Gene position: 807466-807257 (Counterclockwise)

Preceding gene: 148827450

Following gene: 148827446

Centisome position: 42.79

GC content: 41.9

Gene sequence:

>210_bases
TTGACGAATGAACGCACTCGCCGCCAATTAAAAAGTTTACGTCACGCAACTAACAGTGAATTGCTTTGTGAAGCATTCTT
ACACGCATTCACAGGACAACCTTTACCCACCGATGCAGATTTAATGAAAGAGCGTAATGATGAAATCCCTGAAGATGCCA
AAGTGCTTATGCGTGAATTAGGTGTCGATCCAGAAAGCTGGGAATATTAA

Upstream 100 bases:

>100_bases
GGGACGGAAAATATATCAGCCCTTATGCAGAACACGGCAAAAAAAAGTGAGCAAGTAAAAAAAAATTACAGTATCTATTC
CCATTAAAGTACTGGAAATT

Downstream 100 bases:

>100_bases
CCGCACTTTTCACTTATCCGTTCAAGCCATTCAAAATTAAACATTCAGGGTTGTCATTGCCCTGACAACTGTCGTGCCAG
TGCTGCAATTTTTGTACCAT

Product: transcriptional repressor protein MetJ

Products: NA

Alternate protein names: Met regulon regulatory protein metJ [H]

Number of amino acids: Translated: 69; Mature: 68

Protein sequence:

>69_residues
MTNERTRRQLKSLRHATNSELLCEAFLHAFTGQPLPTDADLMKERNDEIPEDAKVLMRELGVDPESWEY

Sequences:

>Translated_69_residues
MTNERTRRQLKSLRHATNSELLCEAFLHAFTGQPLPTDADLMKERNDEIPEDAKVLMRELGVDPESWEY
>Mature_68_residues
TNERTRRQLKSLRHATNSELLCEAFLHAFTGQPLPTDADLMKERNDEIPEDAKVLMRELGVDPESWEY

Specific function: This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis [H]

COG id: COG3060

COG function: function code KE; Transcriptional regulator of met regulon

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the metJ family [H]

Homologues:

Organism=Escherichia coli, GI1790373, Length=69, Percent_Identity=78.2608695652174, Blast_Score=121, Evalue=1e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002084
- InterPro:   IPR010985
- ProDom:   PD020365 [H]

Pfam domain/function: PF01340 MetJ [H]

EC number: NA

Molecular weight: Translated: 8045; Mature: 7914

Theoretical pI: Translated: 4.61; Mature: 4.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNERTRRQLKSLRHATNSELLCEAFLHAFTGQPLPTDADLMKERNDEIPEDAKVLMREL
CCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCHHHHHHHHHH
GVDPESWEY
CCCCCCCCC
>Mature Secondary Structure 
TNERTRRQLKSLRHATNSELLCEAFLHAFTGQPLPTDADLMKERNDEIPEDAKVLMREL
CCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCHHHHHHHHHH
GVDPESWEY
CCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA