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The map label for this gene is udp [H]

Identifier: 148827433

GI number: 148827433

Start: 791695

End: 792453

Strand: Direct

Name: udp [H]

Synonym: CGSHiGG_04195

Alternate gene names: 148827433

Gene position: 791695-792453 (Clockwise)

Preceding gene: 148827429

Following gene: 148827438

Centisome position: 41.95

GC content: 40.97

Gene sequence:

>759_bases
ATGTCAGACGTATTTCACTTAAACCTCACTAAAGCACAACTTAAAGGCGCAACACTCGCTATTGTTCCTGGCGATCCTGC
GCGTAGTGAGCGTATTGCGAAACAACTTGATAATCCAGAGTTTCTTGCAAGCACGCGTGAATTTACATCGTGGTTAGGTT
ATATCAATGGTCAGCCTATTATTGTATGTTCTACGGGTATTGGTGGCCCTTCAACATCAATTTGTGTGGAAGAACTTGCT
CAACTTGGTGTTCGCACTTTCTTACGTATTGGCACAACGGGTGCAATTCAACCGCACATTAATGTAGGCGATGTTCTTAT
CACAACTGCTGCTGTTCGCTTAGATGGTGCAAGCCATCATTTTGTACCATTAGAATATCCAGCTGTGGCAAACTTTGAAT
GTACAACCGCACTTTATAATGCAGCGAAAGCAAAAGGTATTGAGCCTTATGTAGGTGTAACCGTATCATCTGATACATTC
TATCCAGGTCAAGAACGTTACGATACTTATAGTGGTAAAGTATATCGTAATTACCAAGGTTTGCTTAAACAATGGCAAGA
TTTGAATGTAATGAATTACGAAATGGAATCTTCAACATTGTTTACTATGTGTAGCGCATTAGGTTTGCGTGCAGGGATGG
TTGCAGGCGTGATTGTAAACCGCACTCAACAAGAAATTCCAAATGAAGCAACAATAACACAAACGGAAGAAAAAGCTGTG
TCTGTTGTGATCGCAGCTGCACAAGCGTTGTTAAGTTAA

Upstream 100 bases:

>100_bases
GAGAAAAAAATTTTCTAAAAATATTTTATTTCTTTTCTTGAAAATAAGATTTTTCCTAAGGGCGAAATCATCACGTTCAA
TGATAATAAGGAGATTTATT

Downstream 100 bases:

>100_bases
ATTAATATTTATTTGAAACAATAAAACTTTATTTTATTCTGCACCTTAATTAGATTTATTTTCTAACGAAGTAAGGTGCA
GATTTTTTTATTAATAAACT

Product: uridine phosphorylase

Products: NA

Alternate protein names: UPase; UrdPase [H]

Number of amino acids: Translated: 252; Mature: 251

Protein sequence:

>252_residues
MSDVFHLNLTKAQLKGATLAIVPGDPARSERIAKQLDNPEFLASTREFTSWLGYINGQPIIVCSTGIGGPSTSICVEELA
QLGVRTFLRIGTTGAIQPHINVGDVLITTAAVRLDGASHHFVPLEYPAVANFECTTALYNAAKAKGIEPYVGVTVSSDTF
YPGQERYDTYSGKVYRNYQGLLKQWQDLNVMNYEMESSTLFTMCSALGLRAGMVAGVIVNRTQQEIPNEATITQTEEKAV
SVVIAAAQALLS

Sequences:

>Translated_252_residues
MSDVFHLNLTKAQLKGATLAIVPGDPARSERIAKQLDNPEFLASTREFTSWLGYINGQPIIVCSTGIGGPSTSICVEELA
QLGVRTFLRIGTTGAIQPHINVGDVLITTAAVRLDGASHHFVPLEYPAVANFECTTALYNAAKAKGIEPYVGVTVSSDTF
YPGQERYDTYSGKVYRNYQGLLKQWQDLNVMNYEMESSTLFTMCSALGLRAGMVAGVIVNRTQQEIPNEATITQTEEKAV
SVVIAAAQALLS
>Mature_251_residues
SDVFHLNLTKAQLKGATLAIVPGDPARSERIAKQLDNPEFLASTREFTSWLGYINGQPIIVCSTGIGGPSTSICVEELAQ
LGVRTFLRIGTTGAIQPHINVGDVLITTAAVRLDGASHHFVPLEYPAVANFECTTALYNAAKAKGIEPYVGVTVSSDTFY
PGQERYDTYSGKVYRNYQGLLKQWQDLNVMNYEMESSTLFTMCSALGLRAGMVAGVIVNRTQQEIPNEATITQTEEKAVS
VVIAAAQALLS

Specific function: Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synth

COG id: COG2820

COG function: function code F; Uridine phosphorylase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNP/UDP phosphorylase family [H]

Homologues:

Organism=Escherichia coli, GI1790265, Length=250, Percent_Identity=72.8, Blast_Score=388, Evalue=1e-109,
Organism=Escherichia coli, GI1790844, Length=210, Percent_Identity=28.5714285714286, Blast_Score=91, Evalue=7e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018017
- InterPro:   IPR018016
- InterPro:   IPR000845
- InterPro:   IPR010058 [H]

Pfam domain/function: PF01048 PNP_UDP_1 [H]

EC number: =2.4.2.3 [H]

Molecular weight: Translated: 27239; Mature: 27108

Theoretical pI: Translated: 5.29; Mature: 5.29

Prosite motif: PS01232 PNP_UDP_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDVFHLNLTKAQLKGATLAIVPGDPARSERIAKQLDNPEFLASTREFTSWLGYINGQPI
CCCEEEEEEHHHHHCCCEEEEECCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCEE
IVCSTGIGGPSTSICVEELAQLGVRTFLRIGTTGAIQPHINVGDVLITTAAVRLDGASHH
EEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHEEEEEEEECCCCCC
FVPLEYPAVANFECTTALYNAAKAKGIEPYVGVTVSSDTFYPGQERYDTYSGKVYRNYQG
EEECCCCCCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCCHHHCCCCCCEEEECHHH
LLKQWQDLNVMNYEMESSTLFTMCSALGLRAGMVAGVIVNRTQQEIPNEATITQTEEKAV
HHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCEEECHHHHH
SVVIAAAQALLS
HHHHHHHHHHCC
>Mature Secondary Structure 
SDVFHLNLTKAQLKGATLAIVPGDPARSERIAKQLDNPEFLASTREFTSWLGYINGQPI
CCEEEEEEHHHHHCCCEEEEECCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCEE
IVCSTGIGGPSTSICVEELAQLGVRTFLRIGTTGAIQPHINVGDVLITTAAVRLDGASHH
EEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHEEEEEEEECCCCCC
FVPLEYPAVANFECTTALYNAAKAKGIEPYVGVTVSSDTFYPGQERYDTYSGKVYRNYQG
EEECCCCCCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCCHHHCCCCCCEEEECHHH
LLKQWQDLNVMNYEMESSTLFTMCSALGLRAGMVAGVIVNRTQQEIPNEATITQTEEKAV
HHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCEEECHHHHH
SVVIAAAQALLS
HHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]