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The map label for this gene is mltF [H]

Identifier: 148827372

GI number: 148827372

Start: 720061

End: 721509

Strand: Direct

Name: mltF [H]

Synonym: CGSHiGG_03795

Alternate gene names: 148827372

Gene position: 720061-721509 (Clockwise)

Preceding gene: 148827371

Following gene: 148827373

Centisome position: 38.16

GC content: 34.3

Gene sequence:

>1449_bases
TTGAAAGGTCTTTTTTTACGTATTATTACTGCTCTAGCGTTATTATTTTGGGCTATTGATATGGTGTTCCCATGGCAATT
TTTACGTCATACTGAAGAAAATCATTATACTGCAATTCAAGCTAGGGGATCACTTTATGTAGGAACAATAAATAACCAGA
TTTCTTATTTTATTAATAAAGATAGCGAACGAGGCTTTGAATATGAATTAGCCAAAGCATTTGCCGATACTTTAGGCGTA
GAACTCGAAATGAAAATTTTCGATAATCAAGAGCAGTTATTTGATGAACTTAATAAACACAATATTGATTTAGCTGCCGC
CCACCTTTTATACCATCCTAAAAATGCGGAACGTTTCCAAATAGGTCCTGCATATCATTCTGCTTCATGGCAATTAGCTT
ATCGAAAAAATGAAAATCGTCCTAAAAATTTAGGTAACGTAAAGAAAGATATTTATATCTCAAATAATTTAGCATTAGAA
GAAACGTTAAAAGAATTACAAAAACAATATCCACAATTAATTTGGAAAAGAAATCAAGCACTTACTCAAGAAGAACTATT
ACTACAACTGGCTGAAGGCAAAATTCCTTACGTTATTGCAAATTCTATTGATATTGCTGCAATTCAACAAATCAAACCAG
AATTAGCCATTGCCTTTGATATTACTGATGAAGCAAACGTTCACTGGTATTTACCCAATAGCCCCTACCGCGATCTACAA
ACGGCTTTACTCAATTTTATGAATAATGCCGAAGAAACGGGACTTTTAGATAATTTAAAAGAAAAATATTTAGGACATAT
TTCACAATTTGATTACGTAGATACGCGCTCTTATATGAACGCAATTGAAAATATCCTGCCACAATTCTCACCGCTCTTTG
AAAAATACAAAGGTGAATTAGATTGGAGATTACTCGCAGCAGTGGCTTATCAAGAATCTCATTGGAATCCAGATGCAACA
TCGCCAACTGGAGTACGTGGCATAATGATGCTCACCAAAAATACCGCACAACATATGAAAATCAGCGATAGAACAGATCC
TGAACAAAGTATTAAAGCTGGTTCAGAATATTTACACTGGTTGATTAGTCAGCTTCCTGAAAGCATTGAAAAGGAAGAAA
GAATTTGGTTTGCCTTAGTTGCCTATAACATAGGACTCGGTCACTTAATTGATGCACGCCGTTTAACTCAAAATCTTGGA
GGAAATCCAGATAATTGGCTCAATGTGAAAAAAAATCTGCCTTTATTAGCAGAAAAACGCTATTATTCCCAACTGAAATA
CGGCTATGCAAGAGGCTATGAAGCCTATCAATATGTAGAAAATATTCGCCGCTATATGAATAGCATCGTAAATTATCATC
GAGTCCAAGAAAATCAAACAACGAATGATAATGCCAACAACGAAAGTGCGGTTAAAAATTTAGAAGAAATAAAGGAAAAT
GAGGATTAA

Upstream 100 bases:

>100_bases
TTTACATACACTTAGCCCCTTGAACCTCAAGGGGGCTTTTTATTGTCTATAGTGAAAGTTTTGGCTACAATCCCATAACT
TTTTTATATAGGAAAAATCA

Downstream 100 bases:

>100_bases
TAAAATGTTAAAACGTAAAACTTTTCTTAAAAAGAAAGCTAATTTACAACAAAGTTCTTTATCACGTAATCTACGTTTAA
GACGTTTAAAACACCGCAAA

Product: putative transglycosylase

Products: NA

Alternate protein names: Murein lyase F [H]

Number of amino acids: Translated: 482; Mature: 482

Protein sequence:

>482_residues
MKGLFLRIITALALLFWAIDMVFPWQFLRHTEENHYTAIQARGSLYVGTINNQISYFINKDSERGFEYELAKAFADTLGV
ELEMKIFDNQEQLFDELNKHNIDLAAAHLLYHPKNAERFQIGPAYHSASWQLAYRKNENRPKNLGNVKKDIYISNNLALE
ETLKELQKQYPQLIWKRNQALTQEELLLQLAEGKIPYVIANSIDIAAIQQIKPELAIAFDITDEANVHWYLPNSPYRDLQ
TALLNFMNNAEETGLLDNLKEKYLGHISQFDYVDTRSYMNAIENILPQFSPLFEKYKGELDWRLLAAVAYQESHWNPDAT
SPTGVRGIMMLTKNTAQHMKISDRTDPEQSIKAGSEYLHWLISQLPESIEKEERIWFALVAYNIGLGHLIDARRLTQNLG
GNPDNWLNVKKNLPLLAEKRYYSQLKYGYARGYEAYQYVENIRRYMNSIVNYHRVQENQTTNDNANNESAVKNLEEIKEN
ED

Sequences:

>Translated_482_residues
MKGLFLRIITALALLFWAIDMVFPWQFLRHTEENHYTAIQARGSLYVGTINNQISYFINKDSERGFEYELAKAFADTLGV
ELEMKIFDNQEQLFDELNKHNIDLAAAHLLYHPKNAERFQIGPAYHSASWQLAYRKNENRPKNLGNVKKDIYISNNLALE
ETLKELQKQYPQLIWKRNQALTQEELLLQLAEGKIPYVIANSIDIAAIQQIKPELAIAFDITDEANVHWYLPNSPYRDLQ
TALLNFMNNAEETGLLDNLKEKYLGHISQFDYVDTRSYMNAIENILPQFSPLFEKYKGELDWRLLAAVAYQESHWNPDAT
SPTGVRGIMMLTKNTAQHMKISDRTDPEQSIKAGSEYLHWLISQLPESIEKEERIWFALVAYNIGLGHLIDARRLTQNLG
GNPDNWLNVKKNLPLLAEKRYYSQLKYGYARGYEAYQYVENIRRYMNSIVNYHRVQENQTTNDNANNESAVKNLEEIKEN
ED
>Mature_482_residues
MKGLFLRIITALALLFWAIDMVFPWQFLRHTEENHYTAIQARGSLYVGTINNQISYFINKDSERGFEYELAKAFADTLGV
ELEMKIFDNQEQLFDELNKHNIDLAAAHLLYHPKNAERFQIGPAYHSASWQLAYRKNENRPKNLGNVKKDIYISNNLALE
ETLKELQKQYPQLIWKRNQALTQEELLLQLAEGKIPYVIANSIDIAAIQQIKPELAIAFDITDEANVHWYLPNSPYRDLQ
TALLNFMNNAEETGLLDNLKEKYLGHISQFDYVDTRSYMNAIENILPQFSPLFEKYKGELDWRLLAAVAYQESHWNPDAT
SPTGVRGIMMLTKNTAQHMKISDRTDPEQSIKAGSEYLHWLISQLPESIEKEERIWFALVAYNIGLGHLIDARRLTQNLG
GNPDNWLNVKKNLPLLAEKRYYSQLKYGYARGYEAYQYVENIRRYMNSIVNYHRVQENQTTNDNANNESAVKNLEEIKEN
ED

Specific function: Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the

COG id: COG4623

COG function: function code M; Predicted soluble lytic transglycosylase fused to an ABC-type amino acid-binding protein

Gene ontology:

Cell location: Cell outer membrane; Peripheral membrane protein. Note=Attached to the inner leaflet of the outer membrane [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the transglycosylase slt family [H]

Homologues:

Organism=Escherichia coli, GI171474010, Length=436, Percent_Identity=51.1467889908257, Blast_Score=444, Evalue=1e-126,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008258
- InterPro:   IPR001638
- InterPro:   IPR000189 [H]

Pfam domain/function: PF00497 SBP_bac_3; PF01464 SLT [H]

EC number: NA

Molecular weight: Translated: 56083; Mature: 56083

Theoretical pI: Translated: 5.64; Mature: 5.64

Prosite motif: PS00922 TRANSGLYCOSYLASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKGLFLRIITALALLFWAIDMVFPWQFLRHTEENHYTAIQARGSLYVGTINNQISYFINK
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCEEEEEECCCEEEEEEC
DSERGFEYELAKAFADTLGVELEMKIFDNQEQLFDELNKHNIDLAAAHLLYHPKNAERFQ
CCCCCCHHHHHHHHHHHHCCEEEEEEECCHHHHHHHHHHCCCHHHHHHHHCCCCCCCEEE
IGPAYHSASWQLAYRKNENRPKNLGNVKKDIYISNNLALEETLKELQKQYPQLIWKRNQA
ECCCCCCCCEEEEEECCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHC
LTQEELLLQLAEGKIPYVIANSIDIAAIQQIKPELAIAFDITDEANVHWYLPNSPYRDLQ
CCHHHHHHHHHCCCCCEEEECCCCHHHHHHCCCCEEEEEEECCCCCEEEECCCCCHHHHH
TALLNFMNNAEETGLLDNLKEKYLGHISQFDYVDTRSYMNAIENILPQFSPLFEKYKGEL
HHHHHHHCCCHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC
DWRLLAAVAYQESHWNPDATSPTGVRGIMMLTKNTAQHMKISDRTDPEQSIKAGSEYLHW
CHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCHHHCEECCCCCHHHHHHHHHHHHHH
LISQLPESIEKEERIWFALVAYNIGLGHLIDARRLTQNLGGNPDNWLNVKKNLPLLAEKR
HHHHHHHHHHHHHHHEEEEHHHHCCHHHHHHHHHHHHHCCCCCCCCEECCCCCCHHHHHH
YYSQLKYGYARGYEAYQYVENIRRYMNSIVNYHRVQENQTTNDNANNESAVKNLEEIKEN
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCC
ED
CC
>Mature Secondary Structure
MKGLFLRIITALALLFWAIDMVFPWQFLRHTEENHYTAIQARGSLYVGTINNQISYFINK
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCEEEEEECCCEEEEEEC
DSERGFEYELAKAFADTLGVELEMKIFDNQEQLFDELNKHNIDLAAAHLLYHPKNAERFQ
CCCCCCHHHHHHHHHHHHCCEEEEEEECCHHHHHHHHHHCCCHHHHHHHHCCCCCCCEEE
IGPAYHSASWQLAYRKNENRPKNLGNVKKDIYISNNLALEETLKELQKQYPQLIWKRNQA
ECCCCCCCCEEEEEECCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHC
LTQEELLLQLAEGKIPYVIANSIDIAAIQQIKPELAIAFDITDEANVHWYLPNSPYRDLQ
CCHHHHHHHHHCCCCCEEEECCCCHHHHHHCCCCEEEEEEECCCCCEEEECCCCCHHHHH
TALLNFMNNAEETGLLDNLKEKYLGHISQFDYVDTRSYMNAIENILPQFSPLFEKYKGEL
HHHHHHHCCCHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC
DWRLLAAVAYQESHWNPDATSPTGVRGIMMLTKNTAQHMKISDRTDPEQSIKAGSEYLHW
CHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCHHHCEECCCCCHHHHHHHHHHHHHH
LISQLPESIEKEERIWFALVAYNIGLGHLIDARRLTQNLGGNPDNWLNVKKNLPLLAEKR
HHHHHHHHHHHHHHHEEEEHHHHCCHHHHHHHHHHHHHCCCCCCCCEECCCCCCHHHHHH
YYSQLKYGYARGYEAYQYVENIRRYMNSIVNYHRVQENQTTNDNANNESAVKNLEEIKEN
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCC
ED
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA