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The map label for this gene is nqrE

Identifier: 148827308

GI number: 148827308

Start: 640313

End: 640909

Strand: Direct

Name: nqrE

Synonym: CGSHiGG_03445

Alternate gene names: 148827308

Gene position: 640313-640909 (Clockwise)

Preceding gene: 148827307

Following gene: 148827309

Centisome position: 33.93

GC content: 36.52

Gene sequence:

>597_bases
ATGGAACATTATATTAGCCTATTTGTTAAGGCAGTCTTCATTGAAAATATGGCACTTTCTTTCTTCTTAGGAATGTGTAC
TTTCTTAGCGGTATCTAAAAAGGTGTCCACTGCGTTTGGTCTTGGGATTGCGGTAACTTTCGTTCTTGGGATCGCAGTGC
CAGTAAACCAATTAATTTATGCAAATGTACTAAAAGAAAATGCTTTAATTGAAGGTGTAGATTTATCATTCTTAAACTTC
ATCACTTTCATTGGGGTTATTGCTGGTTTAGTGCAAATTCTTGAAATGGTGTTAGATAAATTTATGCCATCTCTTTATAA
CGCATTAGGGATTTTCTTACCTTTAATCGCAGTAAACTGTGCGATCTTTGGTGGGGTATCTTTCATGGTTCAACGTGATT
ACAATTTCCCTGAATCTATCGTGTATGGTTTCGGCTCAGGTTTAGGTTGGATGTTGGCGATTGTTGCGCTTGCTGGCTTA
ACTGAGAAAATGAAATATGCGGATATTCCTGCAGGATTAAAAGGTTTAGGTATTACCTTTATCTCTGTTGGTTTAATGGC
ACTAGGCTTTATGTCTTTCTCTGGTATTCAATTATAA

Upstream 100 bases:

>100_bases
AAATGGTTTATTCCTACTTGCACCAAGTGCATTCTTTATCATCGGATTTGTGATCTGGGGATTAAGAACTTGGAAACCAG
AACAACAGGAGAAGTAATCA

Downstream 100 bases:

>100_bases
GGAGTGTAATCAATGAGCGATTCAGTAATTCTTGCACTCGGTATTGCCGCATTCACGGTTATTGTATTAGTGTTAGTGGC
AATCATCTTATTTGCGAAAT

Product: Na(+)-translocating NADH-quinone reductase subunit E

Products: NA

Alternate protein names: Na(+)-NQR subunit E; Na(+)-translocating NQR subunit E; NQR complex subunit E; NQR-1 subunit E

Number of amino acids: Translated: 198; Mature: 198

Protein sequence:

>198_residues
MEHYISLFVKAVFIENMALSFFLGMCTFLAVSKKVSTAFGLGIAVTFVLGIAVPVNQLIYANVLKENALIEGVDLSFLNF
ITFIGVIAGLVQILEMVLDKFMPSLYNALGIFLPLIAVNCAIFGGVSFMVQRDYNFPESIVYGFGSGLGWMLAIVALAGL
TEKMKYADIPAGLKGLGITFISVGLMALGFMSFSGIQL

Sequences:

>Translated_198_residues
MEHYISLFVKAVFIENMALSFFLGMCTFLAVSKKVSTAFGLGIAVTFVLGIAVPVNQLIYANVLKENALIEGVDLSFLNF
ITFIGVIAGLVQILEMVLDKFMPSLYNALGIFLPLIAVNCAIFGGVSFMVQRDYNFPESIVYGFGSGLGWMLAIVALAGL
TEKMKYADIPAGLKGLGITFISVGLMALGFMSFSGIQL
>Mature_198_residues
MEHYISLFVKAVFIENMALSFFLGMCTFLAVSKKVSTAFGLGIAVTFVLGIAVPVNQLIYANVLKENALIEGVDLSFLNF
ITFIGVIAGLVQILEMVLDKFMPSLYNALGIFLPLIAVNCAIFGGVSFMVQRDYNFPESIVYGFGSGLGWMLAIVALAGL
TEKMKYADIPAGLKGLGITFISVGLMALGFMSFSGIQL

Specific function: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to nqrE are probably involved in the second step, the conversion of ubisemiqui

COG id: COG2209

COG function: function code C; Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrE

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nqrDE/rnfAE family

Homologues:

Organism=Escherichia coli, GI1787914, Length=196, Percent_Identity=42.3469387755102, Blast_Score=147, Evalue=4e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NQRE_HAEI8 (Q4QP20)

Other databases:

- EMBL:   CP000057
- RefSeq:   YP_247887.1
- STRING:   Q4QP20
- GeneID:   3429594
- GenomeReviews:   CP000057_GR
- KEGG:   hit:NTHI0258
- eggNOG:   COG2209
- HOGENOM:   HBG624915
- OMA:   FLGMCSF
- PhylomeDB:   Q4QP20
- ProtClustDB:   PRK02830
- BioCyc:   HINF281310:NTHI0258-MONOMER
- HAMAP:   MF_00429
- InterPro:   IPR003667
- InterPro:   IPR010967
- PIRSF:   PIRSF006102
- TIGRFAMs:   TIGR01940

Pfam domain/function: PF02508 Rnf-Nqr

EC number: NA

Molecular weight: Translated: 21310; Mature: 21310

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x120de8a4)-; HASH(0x10bfeb30)-; HASH(0x1204d170)-; HASH(0x107dee9c)-; HASH(0x116d81f8)-; HASH(0x114cb920)-;

Cys/Met content:

1.0 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
5.1 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEHYISLFVKAVFIENMALSFFLGMCTFLAVSKKVSTAFGLGIAVTFVLGIAVPVNQLIY
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ANVLKENALIEGVDLSFLNFITFIGVIAGLVQILEMVLDKFMPSLYNALGIFLPLIAVNC
HHHHHHCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AIFGGVSFMVQRDYNFPESIVYGFGSGLGWMLAIVALAGLTEKMKYADIPAGLKGLGITF
HHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
ISVGLMALGFMSFSGIQL
HHHHHHHHHHHHHCCCCH
>Mature Secondary Structure
MEHYISLFVKAVFIENMALSFFLGMCTFLAVSKKVSTAFGLGIAVTFVLGIAVPVNQLIY
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ANVLKENALIEGVDLSFLNFITFIGVIAGLVQILEMVLDKFMPSLYNALGIFLPLIAVNC
HHHHHHCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AIFGGVSFMVQRDYNFPESIVYGFGSGLGWMLAIVALAGLTEKMKYADIPAGLKGLGITF
HHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
ISVGLMALGFMSFSGIQL
HHHHHHHHHHHHHCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA