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The map label for this gene is nqrD

Identifier: 148827307

GI number: 148827307

Start: 639683

End: 640309

Strand: Direct

Name: nqrD

Synonym: CGSHiGG_03440

Alternate gene names: 148827307

Gene position: 639683-640309 (Clockwise)

Preceding gene: 148827306

Following gene: 148827308

Centisome position: 33.9

GC content: 36.36

Gene sequence:

>627_bases
ATGTCTGGAAAAACAAGTTATAAAGATCTGTTGTTAGCGCCAATTGCTAAAAACAACCCTATTGCATTGCAAATCTTAGG
GATTTGTTCTGCATTAGCTGTAACAACAAAATTAGAAACTGCTTTTGTTATGGCGATTGCAGTTACCTTAGTAACTGGAT
TATCAAACTTATTTGTTTCCCTAATCCGCAATTATATCCCTAACAGCATTCGTATTATTGTACAGCTCGCAATCATCGCT
TCGCTTGTTATCGTAGTGGATCAAATTCTAAAAGCCTATGCTTATGGTTTATCTAAACAACTTTCAGTATTCGTTGGTTT
GATTATTACTAACTGTATCGTAATGGGACGTGCTGAAGCATTTGCGATGAAATCCCCTCCAGTTGAAAGTTTTGTAGATG
GTATCGGAAATGGCTTAGGTTATGGTTCAATGTTAATTATCGTAGCATTTTTCCGTGAACTTATCGGTTCAGGTAAATTA
TTTGGTATGACGATTTTCGAAACTATTCAAAATGGTGGCTGGTATCAAGCAAATGGTTTATTCCTACTTGCACCAAGTGC
ATTCTTTATCATCGGATTTGTGATCTGGGGATTAAGAACTTGGAAACCAGAACAACAGGAGAAGTAA

Upstream 100 bases:

>100_bases
CAACTTTAACAGGTAATGGTGTTCAAGGTACCTTTAATTATTGGTTCAGCAAAGATGGCTTTGGTCCATATCTTGAAAAA
CTTCATTCAGGAGCAAACTA

Downstream 100 bases:

>100_bases
TCAATGGAACATTATATTAGCCTATTTGTTAAGGCAGTCTTCATTGAAAATATGGCACTTTCTTTCTTCTTAGGAATGTG
TACTTTCTTAGCGGTATCTA

Product: Na(+)-translocating NADH-quinone reductase subunit D

Products: NA

Alternate protein names: Na(+)-NQR subunit D; Na(+)-translocating NQR subunit D; NQR complex subunit D; NQR-1 subunit D

Number of amino acids: Translated: 208; Mature: 207

Protein sequence:

>208_residues
MSGKTSYKDLLLAPIAKNNPIALQILGICSALAVTTKLETAFVMAIAVTLVTGLSNLFVSLIRNYIPNSIRIIVQLAIIA
SLVIVVDQILKAYAYGLSKQLSVFVGLIITNCIVMGRAEAFAMKSPPVESFVDGIGNGLGYGSMLIIVAFFRELIGSGKL
FGMTIFETIQNGGWYQANGLFLLAPSAFFIIGFVIWGLRTWKPEQQEK

Sequences:

>Translated_208_residues
MSGKTSYKDLLLAPIAKNNPIALQILGICSALAVTTKLETAFVMAIAVTLVTGLSNLFVSLIRNYIPNSIRIIVQLAIIA
SLVIVVDQILKAYAYGLSKQLSVFVGLIITNCIVMGRAEAFAMKSPPVESFVDGIGNGLGYGSMLIIVAFFRELIGSGKL
FGMTIFETIQNGGWYQANGLFLLAPSAFFIIGFVIWGLRTWKPEQQEK
>Mature_207_residues
SGKTSYKDLLLAPIAKNNPIALQILGICSALAVTTKLETAFVMAIAVTLVTGLSNLFVSLIRNYIPNSIRIIVQLAIIAS
LVIVVDQILKAYAYGLSKQLSVFVGLIITNCIVMGRAEAFAMKSPPVESFVDGIGNGLGYGSMLIIVAFFRELIGSGKLF
GMTIFETIQNGGWYQANGLFLLAPSAFFIIGFVIWGLRTWKPEQQEK

Specific function: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to nqrE are probably involved in the second step, the conversion of ubisemiqui

COG id: COG1347

COG function: function code C; Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrD

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nqrDE/rnfAE family

Homologues:

Organism=Escherichia coli, GI1787919, Length=204, Percent_Identity=38.7254901960784, Blast_Score=115, Evalue=2e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NQRD_HAEI8 (Q4QP21)

Other databases:

- EMBL:   CP000057
- RefSeq:   YP_247886.1
- STRING:   Q4QP21
- GeneID:   3429593
- GenomeReviews:   CP000057_GR
- KEGG:   hit:NTHI0257
- eggNOG:   COG1347
- HOGENOM:   HBG624915
- OMA:   GGWYVPN
- PhylomeDB:   Q4QP21
- ProtClustDB:   PRK09292
- BioCyc:   HINF281310:NTHI0257-MONOMER
- HAMAP:   MF_00428
- InterPro:   IPR003667
- InterPro:   IPR011292
- PIRSF:   PIRSF006102
- TIGRFAMs:   TIGR01939

Pfam domain/function: PF02508 Rnf-Nqr

EC number: NA

Molecular weight: Translated: 22528; Mature: 22397

Theoretical pI: Translated: 9.64; Mature: 9.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x10ce56a4)-; HASH(0x120589f0)-; HASH(0x1189de88)-; HASH(0x11b45020)-; HASH(0x120e63c4)-;

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGKTSYKDLLLAPIAKNNPIALQILGICSALAVTTKLETAFVMAIAVTLVTGLSNLFVS
CCCCCCHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LIRNYIPNSIRIIVQLAIIASLVIVVDQILKAYAYGLSKQLSVFVGLIITNCIVMGRAEA
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
FAMKSPPVESFVDGIGNGLGYGSMLIIVAFFRELIGSGKLFGMTIFETIQNGGWYQANGL
HHCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCEEEECCE
FLLAPSAFFIIGFVIWGLRTWKPEQQEK
EEECCHHHHHHHHHHHHHHCCCCCCCCH
>Mature Secondary Structure 
SGKTSYKDLLLAPIAKNNPIALQILGICSALAVTTKLETAFVMAIAVTLVTGLSNLFVS
CCCCCHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LIRNYIPNSIRIIVQLAIIASLVIVVDQILKAYAYGLSKQLSVFVGLIITNCIVMGRAEA
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
FAMKSPPVESFVDGIGNGLGYGSMLIIVAFFRELIGSGKLFGMTIFETIQNGGWYQANGL
HHCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCEEEECCE
FLLAPSAFFIIGFVIWGLRTWKPEQQEK
EEECCHHHHHHHHHHHHHHCCCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA