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The map label for this gene is tesB [H]

Identifier: 148827227

GI number: 148827227

Start: 536931

End: 537791

Strand: Direct

Name: tesB [H]

Synonym: CGSHiGG_02920

Alternate gene names: 148827227

Gene position: 536931-537791 (Clockwise)

Preceding gene: 148827226

Following gene: 148827228

Centisome position: 28.45

GC content: 40.3

Gene sequence:

>861_bases
ATGTCAGATATTCTCAATAACCTCATTCATCTTCTGAAACTTGAAAAAATTGATGATTTAATCTTTCGTGGAGAAAGCCA
AGATTTAGGTTTTCGCCAAGTATTTGGCGGGCAAGTAGTGGCACAGGCGTTATCTGCAGCAATGCAGGTGGCGCCAGAAG
ATCGCATTTTACATTCTTGTCATGCCTATTTTCTTGCCCCAGGAGACAGCCAATATCCGATTATTTACGATGTGGAAACC
TTGCGTGAAGGGCGTAACTTTTCTGCATTACGCGTAAAAGCCATTCAACATAAAAATACCATTTGTCATGTAACCGCTTC
TTTCCAAGTGCCAGAAAAAGGTTTTGAACATCAAAATGCAATGCCAAATGTTGGCGTGCCTGAAGACTTTACAGATGAAA
ATGTGATGCTACAAAAAGTGGCTCAAACCTTGCCAGAACCACTCAATGAAAAATTTGCGGCAGAGCGTCCATTTGAGGTA
CGTACCAAATATTTGAATAACCCATTTAACGGGACAAAATTGCCAGCCGAGCAATATTCTTGGTTTAAAACCAATGGTGA
AACGCCGCTTGATATAAAAATTCAGCAATGTTTATTGGCTTATTTTTCCGATTTTCACTGTATTTTGACCGCACTTCATC
CGCACGAAAAAGGCTTTTTACAAAAAGGAATGAAAGTGGCAACCATTGATCATAGTATTTGGTTCCATCGTCCGTTTGAT
TTAAATCACTGGCATTTGCACGCAATTGAAAGCAATAATGCCTTTGGAGGCCGTGGTTTGGCGCACGGGCAAATTTTCTC
GCAAGATGGTCAATTAATCGCGACAACACAACAAGAAGGTTTGATCCGTTTTAACGAATAA

Upstream 100 bases:

>100_bases
GCACGCATTTTTTAATGCGTGCTTTTTGTTTCCAACTTTGGCATTCCTAAAAATCTCCGTTAAAATAACCGCACTTTTTC
TTATCTTCTAGGAAAGCAAT

Downstream 100 bases:

>100_bases
GAGAAAAAATGACCGCACTTATTACACAATTTTGGCAACAAGTTGAAACCGCGCAAACCTTGAAATCCTATATTAAGAAA
TGATGAAAAAATAAAAAGAC

Product: anaerobic ribonucleoside triphosphate reductase

Products: Hydrolyzed acyl-CoA thioesters [C]

Alternate protein names: Acyl-CoA thioesterase II; TEII [H]

Number of amino acids: Translated: 286; Mature: 285

Protein sequence:

>286_residues
MSDILNNLIHLLKLEKIDDLIFRGESQDLGFRQVFGGQVVAQALSAAMQVAPEDRILHSCHAYFLAPGDSQYPIIYDVET
LREGRNFSALRVKAIQHKNTICHVTASFQVPEKGFEHQNAMPNVGVPEDFTDENVMLQKVAQTLPEPLNEKFAAERPFEV
RTKYLNNPFNGTKLPAEQYSWFKTNGETPLDIKIQQCLLAYFSDFHCILTALHPHEKGFLQKGMKVATIDHSIWFHRPFD
LNHWHLHAIESNNAFGGRGLAHGQIFSQDGQLIATTQQEGLIRFNE

Sequences:

>Translated_286_residues
MSDILNNLIHLLKLEKIDDLIFRGESQDLGFRQVFGGQVVAQALSAAMQVAPEDRILHSCHAYFLAPGDSQYPIIYDVET
LREGRNFSALRVKAIQHKNTICHVTASFQVPEKGFEHQNAMPNVGVPEDFTDENVMLQKVAQTLPEPLNEKFAAERPFEV
RTKYLNNPFNGTKLPAEQYSWFKTNGETPLDIKIQQCLLAYFSDFHCILTALHPHEKGFLQKGMKVATIDHSIWFHRPFD
LNHWHLHAIESNNAFGGRGLAHGQIFSQDGQLIATTQQEGLIRFNE
>Mature_285_residues
SDILNNLIHLLKLEKIDDLIFRGESQDLGFRQVFGGQVVAQALSAAMQVAPEDRILHSCHAYFLAPGDSQYPIIYDVETL
REGRNFSALRVKAIQHKNTICHVTASFQVPEKGFEHQNAMPNVGVPEDFTDENVMLQKVAQTLPEPLNEKFAAERPFEVR
TKYLNNPFNGTKLPAEQYSWFKTNGETPLDIKIQQCLLAYFSDFHCILTALHPHEKGFLQKGMKVATIDHSIWFHRPFDL
NHWHLHAIESNNAFGGRGLAHGQIFSQDGQLIATTQQEGLIRFNE

Specific function: Can hydrolyze a broad range of acyl-CoA thioesters. Its physiological function is not known [H]

COG id: COG1946

COG function: function code I; Acyl-CoA thioesterase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the C/M/P thioester hydrolase family [H]

Homologues:

Organism=Homo sapiens, GI34577075, Length=283, Percent_Identity=37.1024734982332, Blast_Score=184, Evalue=1e-46,
Organism=Escherichia coli, GI1786657, Length=269, Percent_Identity=51.6728624535316, Blast_Score=300, Evalue=6e-83,
Organism=Caenorhabditis elegans, GI17558508, Length=310, Percent_Identity=33.5483870967742, Blast_Score=139, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI71988741, Length=299, Percent_Identity=30.1003344481605, Blast_Score=134, Evalue=8e-32,
Organism=Caenorhabditis elegans, GI212645202, Length=292, Percent_Identity=34.9315068493151, Blast_Score=129, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI17531889, Length=270, Percent_Identity=34.0740740740741, Blast_Score=128, Evalue=3e-30,
Organism=Caenorhabditis elegans, GI115532456, Length=271, Percent_Identity=33.9483394833948, Blast_Score=128, Evalue=3e-30,
Organism=Caenorhabditis elegans, GI17531885, Length=270, Percent_Identity=34.0740740740741, Blast_Score=127, Evalue=5e-30,
Organism=Caenorhabditis elegans, GI71982224, Length=300, Percent_Identity=29, Blast_Score=93, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003703 [H]

Pfam domain/function: PF02551 Acyl_CoA_thio [H]

EC number: 3.1.2.- [C]

Molecular weight: Translated: 32493; Mature: 32362

Theoretical pI: Translated: 6.45; Mature: 6.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDILNNLIHLLKLEKIDDLIFRGESQDLGFRQVFGGQVVAQALSAAMQVAPEDRILHSC
CHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
HAYFLAPGDSQYPIIYDVETLREGRNFSALRVKAIQHKNTICHVTASFQVPEKGFEHQNA
HEEEECCCCCCCCEEEEHHHHHCCCCCCCEEEEEECCCCEEEEEEEECCCCCCCCCCCCC
MPNVGVPEDFTDENVMLQKVAQTLPEPLNEKFAAERPFEVRTKYLNNPFNGTKLPAEQYS
CCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCHHHCC
WFKTNGETPLDIKIQQCLLAYFSDFHCILTALHPHEKGFLQKGMKVATIDHSIWFHRPFD
EEECCCCCCEEHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCEEEEEECCEEEECCCC
LNHWHLHAIESNNAFGGRGLAHGQIFSQDGQLIATTQQEGLIRFNE
CCCEEEEEEECCCCCCCCCCCCCEEECCCCCEEEEECCCCCEEECC
>Mature Secondary Structure 
SDILNNLIHLLKLEKIDDLIFRGESQDLGFRQVFGGQVVAQALSAAMQVAPEDRILHSC
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
HAYFLAPGDSQYPIIYDVETLREGRNFSALRVKAIQHKNTICHVTASFQVPEKGFEHQNA
HEEEECCCCCCCCEEEEHHHHHCCCCCCCEEEEEECCCCEEEEEEEECCCCCCCCCCCCC
MPNVGVPEDFTDENVMLQKVAQTLPEPLNEKFAAERPFEVRTKYLNNPFNGTKLPAEQYS
CCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCHHHCC
WFKTNGETPLDIKIQQCLLAYFSDFHCILTALHPHEKGFLQKGMKVATIDHSIWFHRPFD
EEECCCCCCEEHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCEEEEEECCEEEECCCC
LNHWHLHAIESNNAFGGRGLAHGQIFSQDGQLIATTQQEGLIRFNE
CCCEEEEEEECCCCCCCCCCCCCEEECCCCCEEEEECCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA thioesters [C]

Specific reaction: Hydrolyzes a broad range of acyl-CoA thioesters [C]

General reaction: Hydrolase; Acting on ester bonds; Thiolester hydrolases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]