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The map label for this gene is ppnK [H]

Identifier: 148827222

GI number: 148827222

Start: 532031

End: 532921

Strand: Reverse

Name: ppnK [H]

Synonym: CGSHiGG_02885

Alternate gene names: 148827222

Gene position: 532921-532031 (Counterclockwise)

Preceding gene: 148827224

Following gene: 148827214

Centisome position: 28.24

GC content: 37.26

Gene sequence:

>891_bases
ATGAATCATTTATATCGTTCCTTTAAAACCATTGCTCTTGTAGGTAAGCCTCGCAATGATATTAACTTACAAATGCACAA
AAACTTATTTCATTGGTTAATGGAACGTGGTTATCAAGTGTTGGTGGAAAAAGAAGTCGCCATAACACTTGAGTTACCTT
TTGAACATCTTGCTACGTTAGAAGAAATAGGTCGCCGAGCCCAATTAGCCATTGTGATTGGTGGAGACGGCAATATGCTA
GGGCGCGCTCGCGTATTAGCAAAATATGATATTCCATTGATTGGTATTAATCGTGGTAATTTGGGATTTTTAACGGATAT
TGACCCGAAGAATGCCTATTCCCAGCTTGAAGCTTGTTTAGAACGTGGCGAATTTTTTGTGGAAGAACGTTTTTTATTGG
AAGCAAAAATCGAACGAGCAAGTGAAATCGTATCAACCAGCAATGCGGTAAATGAAGCGGTTATTCATCCCGCTAAAATT
GCACATATGATAGATTTTCACGTATATATCAATGATAAGTTTGCATTTTCTCAACGTTCTGATGGATTAATTGTTTCTAC
TCCAACAGGTTCTACGGCTTATTCTCTTTCCGCTGGTGGACCTATTTTGACACCAAACCTTAATGCCATTGCATTAGTGC
CAATGTTTCCACATACATTAACTTCTCGCCCTCTTGTTGTTGATGGGGATAGTAAAATATCGATTCGTTTTGCTGAACAT
AATACCTCTCAATTAGAAGTGGGCTGTGATAGTCAAATTACCTTACCTTTTACCCCAGATGATGTGGTGCATATTCAAAA
AAGCGAGCATAAACTCCGATTGCTTCATCTGAAAAATTATAATTATTACAATGTGTTAAGTAGCAAATTAGGTTGGTTAA
AATCATTTTGA

Upstream 100 bases:

>100_bases
TTTTTTTCTCCGTAAAACAAAATTGATTAATCGTAATTGGGCATAGTGTAGCAAAAAACGATATAATGACGAAAATGTTA
AATTCAAGTGCGGTCATTTT

Downstream 100 bases:

>100_bases
TTATGGTAAAAATTTTCGATTGAAATAGATTTGACAAAATACTGTAAAAAATCCTTTACTGTAAATTAAATCAGTTATAT
CATATTAAATATACAGTTAA

Product: inorganic polyphosphate/ATP-NAD kinase

Products: NA

Alternate protein names: Poly(P)/ATP NAD kinase [H]

Number of amino acids: Translated: 296; Mature: 296

Protein sequence:

>296_residues
MNHLYRSFKTIALVGKPRNDINLQMHKNLFHWLMERGYQVLVEKEVAITLELPFEHLATLEEIGRRAQLAIVIGGDGNML
GRARVLAKYDIPLIGINRGNLGFLTDIDPKNAYSQLEACLERGEFFVEERFLLEAKIERASEIVSTSNAVNEAVIHPAKI
AHMIDFHVYINDKFAFSQRSDGLIVSTPTGSTAYSLSAGGPILTPNLNAIALVPMFPHTLTSRPLVVDGDSKISIRFAEH
NTSQLEVGCDSQITLPFTPDDVVHIQKSEHKLRLLHLKNYNYYNVLSSKLGWLKSF

Sequences:

>Translated_296_residues
MNHLYRSFKTIALVGKPRNDINLQMHKNLFHWLMERGYQVLVEKEVAITLELPFEHLATLEEIGRRAQLAIVIGGDGNML
GRARVLAKYDIPLIGINRGNLGFLTDIDPKNAYSQLEACLERGEFFVEERFLLEAKIERASEIVSTSNAVNEAVIHPAKI
AHMIDFHVYINDKFAFSQRSDGLIVSTPTGSTAYSLSAGGPILTPNLNAIALVPMFPHTLTSRPLVVDGDSKISIRFAEH
NTSQLEVGCDSQITLPFTPDDVVHIQKSEHKLRLLHLKNYNYYNVLSSKLGWLKSF
>Mature_296_residues
MNHLYRSFKTIALVGKPRNDINLQMHKNLFHWLMERGYQVLVEKEVAITLELPFEHLATLEEIGRRAQLAIVIGGDGNML
GRARVLAKYDIPLIGINRGNLGFLTDIDPKNAYSQLEACLERGEFFVEERFLLEAKIERASEIVSTSNAVNEAVIHPAKI
AHMIDFHVYINDKFAFSQRSDGLIVSTPTGSTAYSLSAGGPILTPNLNAIALVPMFPHTLTSRPLVVDGDSKISIRFAEH
NTSQLEVGCDSQITLPFTPDDVVHIQKSEHKLRLLHLKNYNYYNVLSSKLGWLKSF

Specific function: Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus [H]

COG id: COG0061

COG function: function code G; Predicted sugar kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD kinase family [H]

Homologues:

Organism=Homo sapiens, GI55743112, Length=327, Percent_Identity=26.9113149847095, Blast_Score=81, Evalue=1e-15,
Organism=Escherichia coli, GI1788968, Length=289, Percent_Identity=57.439446366782, Blast_Score=344, Evalue=4e-96,
Organism=Saccharomyces cerevisiae, GI6320794, Length=240, Percent_Identity=29.5833333333333, Blast_Score=112, Evalue=6e-26,
Organism=Saccharomyces cerevisiae, GI6322509, Length=239, Percent_Identity=26.7782426778243, Blast_Score=97, Evalue=3e-21,
Organism=Saccharomyces cerevisiae, GI6325068, Length=180, Percent_Identity=30.5555555555556, Blast_Score=96, Evalue=6e-21,
Organism=Drosophila melanogaster, GI28573826, Length=271, Percent_Identity=29.1512915129151, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI28573832, Length=203, Percent_Identity=31.5270935960591, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI28573830, Length=203, Percent_Identity=31.5270935960591, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI28573828, Length=271, Percent_Identity=29.1512915129151, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI161077047, Length=203, Percent_Identity=31.5270935960591, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24653424, Length=229, Percent_Identity=28.3842794759825, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI281363323, Length=229, Percent_Identity=28.3842794759825, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI20129957, Length=229, Percent_Identity=28.3842794759825, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI281363321, Length=229, Percent_Identity=28.3842794759825, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24653422, Length=229, Percent_Identity=28.3842794759825, Blast_Score=66, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016064
- InterPro:   IPR017438
- InterPro:   IPR017437
- InterPro:   IPR002504 [H]

Pfam domain/function: PF01513 NAD_kinase [H]

EC number: =2.7.1.23 [H]

Molecular weight: Translated: 33238; Mature: 33238

Theoretical pI: Translated: 7.17; Mature: 7.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNHLYRSFKTIALVGKPRNDINLQMHKNLFHWLMERGYQVLVEKEVAITLELPFEHLATL
CCHHHHCCEEEEEEECCCCCCEEEEHHHHHHHHHHCCCEEEEEEEEEEEEECCHHHHHHH
EEIGRRAQLAIVIGGDGNMLGRARVLAKYDIPLIGINRGNLGFLTDIDPKNAYSQLEACL
HHCCCCEEEEEEECCCCCEECCEEEEEEECCCEEEECCCCEEEEEECCCHHHHHHHHHHH
ERGEFFVEERFLLEAKIERASEIVSTSNAVNEAVIHPAKIAHMIDFHVYINDKFAFSQRS
HCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCHHHEEEEEEEEEEECCEEEECCCC
DGLIVSTPTGSTAYSLSAGGPILTPNLNAIALVPMFPHTLTSRPLVVDGDSKISIRFAEH
CCEEEECCCCCCEEEECCCCCEECCCCCEEEEEECCCCHHCCCCEEEECCCEEEEEEECC
NTSQLEVGCDSQITLPFTPDDVVHIQKSEHKLRLLHLKNYNYYNVLSSKLGWLKSF
CCCEEEECCCCEEEEECCCCCEEEEECCCCEEEEEEEECCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNHLYRSFKTIALVGKPRNDINLQMHKNLFHWLMERGYQVLVEKEVAITLELPFEHLATL
CCHHHHCCEEEEEEECCCCCCEEEEHHHHHHHHHHCCCEEEEEEEEEEEEECCHHHHHHH
EEIGRRAQLAIVIGGDGNMLGRARVLAKYDIPLIGINRGNLGFLTDIDPKNAYSQLEACL
HHCCCCEEEEEEECCCCCEECCEEEEEEECCCEEEECCCCEEEEEECCCHHHHHHHHHHH
ERGEFFVEERFLLEAKIERASEIVSTSNAVNEAVIHPAKIAHMIDFHVYINDKFAFSQRS
HCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCHHHEEEEEEEEEEECCEEEECCCC
DGLIVSTPTGSTAYSLSAGGPILTPNLNAIALVPMFPHTLTSRPLVVDGDSKISIRFAEH
CCEEEECCCCCCEEEECCCCCEECCCCCEEEEEECCCCHHCCCCEEEECCCEEEEEEECC
NTSQLEVGCDSQITLPFTPDDVVHIQKSEHKLRLLHLKNYNYYNVLSSKLGWLKSF
CCCEEEECCCCEEEEECCCCCEEEEECCCCEEEEEEEECCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA