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The map label for this gene is prc [H]

Identifier: 148827094

GI number: 148827094

Start: 365690

End: 367777

Strand: Reverse

Name: prc [H]

Synonym: CGSHiGG_02065

Alternate gene names: 148827094

Gene position: 367777-365690 (Counterclockwise)

Preceding gene: 148827095

Following gene: 148827093

Centisome position: 19.49

GC content: 35.11

Gene sequence:

>2088_bases
ATGAAATTTAAAATGTCAAAAAATGTGATTTGTTATGCGTGGTTATCGGTGTGTTTGAGCAGTGCAATTCCTGCATTTGC
TGTACAACCTACATTAAAACCAAGTGACATTAGTATTCCAGCGATAAGTGAAGAAAGCCAGTTGGCAACTAAGCGTGCAA
CGACAAGATTAACTCAATCCCATTATCGTAAGATTAAATTAGATGATGATTTTTCCGAGAAAATTTTTGATCGTTATATT
AAAAATTTAGATTTTAACCACAATACTTTTTTGCAGTCTGATATAGACGAACTTCGTCAAAAATATGGTACTAAGTTAGA
TGAACAGTTGAATCAAGGCGATCTTTCTGCGGCGTTTGACATTTATGATGTAATGATGAAACGTCGCTATGAACGTTATA
CTTATGCGTTATCTTTATTAGATAAAGAGCCTGATTTAAATGGTCAAGATCAAATTGAAATTGATCGTGAAAAAGCGGCT
GCGCCACAAACTGAAGCTGATGCGAATAAACTTTGGGATGCTCGCGTAAAAAATGACATTATTAATCTTAAATTAAAAGA
TAAAAAATGGTCAGAAATCAAAGCAAAGCTTACAAAACGCTATAATTTAGCCATTCGTCGTTTAACGCAAACAAAAGCAG
ACGATATTGTTCAAATTTATTTGAATGCTTTTGCGCGTGAAATTGATCCTCACACCAGTTATCTTTCCCCAAGAACAGCA
AAAAGTTTTAATGAAAGTATAAATCTTTCTTTGGAAGGCATTGGGACTACTTTACAATCAGAAGATGATGAAATTAGCAT
CAAATCTCTTGTACCTGGTGCGCCAGCGGAACGTAGTAAAAAGCTGCATCCTGGGGATAAAATCATTGGTGTTGGGCAAG
CAACAGGCGATATTGAAGACGTTGTTGGTTGGCGTTTAGAAGATTTGGTAGAAAAAATTAAAGGGAAAAAAGGCACTAAA
GTTCGCTTAGAAATTGAGCCTGCTAAAGGGGGAAAATCACGTATTATTACTTTGGTTCGTGATAAAGTCCGTATTGAAGA
TCAAGCGGCTAAACTAACCTTTGAAAAAGTGTCAGGAAAAAACATTGCGGTAATAAAAATTCCAAGTTTTTATATTGGAT
TAACCGAAGATGTCAAAAAACTACTGGTTAAATTAGAAAATCAAAAAGCTGAGGCTCTTATTGTTGATTTACGTGAAAAT
GGCGGTGGTGCATTAACGGAAGCGGTAGCGTTAAGTGGTTTATTTATTGCCGATGGCCCTGTTGTGCAGGTTCGCGATGC
TTATCAGCGTATTCGTGTTCATGAAGATGATGATGCTACGCAACAATATAAGGGGTTATTATTTGTGATGATTAATCGTT
ACAGTGCTTCCGCATCAGAAATTTTTGCTGCAGCAATGCAAGATTATCGTCGAGGTATTATCATCGGGCAAAATACTTTT
GGTAAAGGTACGGTGCAACAGAGTCGTTCGTTAAATTTTATCTATGATTTAGATCAGAGTCCGCTGGGTGTTTTGCAATA
TACTATTCAAAAATTTTATCGTATTAATGGTGGTTCAACCCAATTAAAAGGTGTTGCAGCCGATATTAATTTTCCTGAAA
TTATAGATTCGAAAGAATATGGGGAAGATAAAGAAGATAATGCGCTTGCTTGGGATAAAATCCCATCAGCGAGTTATATG
GAAGTAGGAAATATCGATTATATTGATAATGCAGTAAATATTCTAAATGAAAAACATCTTGCTCGTATTGCTAAAGATCC
TGAATTTGTTGCATTGAATGAAGAATTGAAAGTGCGAAATGAACGCCGAGATCGAAAATTTCTATCATTGAATTATAAAA
TGCGTAAAGCAGAGAATGATAAAGATGATGCAAGACGTTTAAAAGATTTGAACGAACGTTTTAAACGTGAGGGTAAGAAA
GCATTGAAAGATATTGATGATTTGCCGAAAGATTACGAAGCACCAGATTTCTTCTTAAAAGAAGCTGAAAAAATGGCAGC
TGATTTCGTTATTTTTAATTCAGATCAGAAAATTAATCAAGCAAACGGCCTATCCGAAGCAAAAACGGAAAGTAAAAATA
AATACTAA

Upstream 100 bases:

>100_bases
AAAAGATTCAGCACGTGTTGAACTTGAAAACGGTTTGATTATGAACGTTGCTGCAGATCGTTTATTTGCTTAATAAATAA
AAATTGACTCGGAAATGGTT

Downstream 100 bases:

>100_bases
ATGGTTTTGACCGCACTTTGTTTGAGAAAAGCAACAAGTGCGGTGATTTTAATAAAGGTTTAGGAAATGGTAGTGTTTAA
AAGCACCTTAAAGTTATCAT

Product: carboxy-terminal protease

Products: NA

Alternate protein names: C-terminal-processing peptidase; Protease Re [H]

Number of amino acids: Translated: 695; Mature: 695

Protein sequence:

>695_residues
MKFKMSKNVICYAWLSVCLSSAIPAFAVQPTLKPSDISIPAISEESQLATKRATTRLTQSHYRKIKLDDDFSEKIFDRYI
KNLDFNHNTFLQSDIDELRQKYGTKLDEQLNQGDLSAAFDIYDVMMKRRYERYTYALSLLDKEPDLNGQDQIEIDREKAA
APQTEADANKLWDARVKNDIINLKLKDKKWSEIKAKLTKRYNLAIRRLTQTKADDIVQIYLNAFAREIDPHTSYLSPRTA
KSFNESINLSLEGIGTTLQSEDDEISIKSLVPGAPAERSKKLHPGDKIIGVGQATGDIEDVVGWRLEDLVEKIKGKKGTK
VRLEIEPAKGGKSRIITLVRDKVRIEDQAAKLTFEKVSGKNIAVIKIPSFYIGLTEDVKKLLVKLENQKAEALIVDLREN
GGGALTEAVALSGLFIADGPVVQVRDAYQRIRVHEDDDATQQYKGLLFVMINRYSASASEIFAAAMQDYRRGIIIGQNTF
GKGTVQQSRSLNFIYDLDQSPLGVLQYTIQKFYRINGGSTQLKGVAADINFPEIIDSKEYGEDKEDNALAWDKIPSASYM
EVGNIDYIDNAVNILNEKHLARIAKDPEFVALNEELKVRNERRDRKFLSLNYKMRKAENDKDDARRLKDLNERFKREGKK
ALKDIDDLPKDYEAPDFFLKEAEKMAADFVIFNSDQKINQANGLSEAKTESKNKY

Sequences:

>Translated_695_residues
MKFKMSKNVICYAWLSVCLSSAIPAFAVQPTLKPSDISIPAISEESQLATKRATTRLTQSHYRKIKLDDDFSEKIFDRYI
KNLDFNHNTFLQSDIDELRQKYGTKLDEQLNQGDLSAAFDIYDVMMKRRYERYTYALSLLDKEPDLNGQDQIEIDREKAA
APQTEADANKLWDARVKNDIINLKLKDKKWSEIKAKLTKRYNLAIRRLTQTKADDIVQIYLNAFAREIDPHTSYLSPRTA
KSFNESINLSLEGIGTTLQSEDDEISIKSLVPGAPAERSKKLHPGDKIIGVGQATGDIEDVVGWRLEDLVEKIKGKKGTK
VRLEIEPAKGGKSRIITLVRDKVRIEDQAAKLTFEKVSGKNIAVIKIPSFYIGLTEDVKKLLVKLENQKAEALIVDLREN
GGGALTEAVALSGLFIADGPVVQVRDAYQRIRVHEDDDATQQYKGLLFVMINRYSASASEIFAAAMQDYRRGIIIGQNTF
GKGTVQQSRSLNFIYDLDQSPLGVLQYTIQKFYRINGGSTQLKGVAADINFPEIIDSKEYGEDKEDNALAWDKIPSASYM
EVGNIDYIDNAVNILNEKHLARIAKDPEFVALNEELKVRNERRDRKFLSLNYKMRKAENDKDDARRLKDLNERFKREGKK
ALKDIDDLPKDYEAPDFFLKEAEKMAADFVIFNSDQKINQANGLSEAKTESKNKY
>Mature_695_residues
MKFKMSKNVICYAWLSVCLSSAIPAFAVQPTLKPSDISIPAISEESQLATKRATTRLTQSHYRKIKLDDDFSEKIFDRYI
KNLDFNHNTFLQSDIDELRQKYGTKLDEQLNQGDLSAAFDIYDVMMKRRYERYTYALSLLDKEPDLNGQDQIEIDREKAA
APQTEADANKLWDARVKNDIINLKLKDKKWSEIKAKLTKRYNLAIRRLTQTKADDIVQIYLNAFAREIDPHTSYLSPRTA
KSFNESINLSLEGIGTTLQSEDDEISIKSLVPGAPAERSKKLHPGDKIIGVGQATGDIEDVVGWRLEDLVEKIKGKKGTK
VRLEIEPAKGGKSRIITLVRDKVRIEDQAAKLTFEKVSGKNIAVIKIPSFYIGLTEDVKKLLVKLENQKAEALIVDLREN
GGGALTEAVALSGLFIADGPVVQVRDAYQRIRVHEDDDATQQYKGLLFVMINRYSASASEIFAAAMQDYRRGIIIGQNTF
GKGTVQQSRSLNFIYDLDQSPLGVLQYTIQKFYRINGGSTQLKGVAADINFPEIIDSKEYGEDKEDNALAWDKIPSASYM
EVGNIDYIDNAVNILNEKHLARIAKDPEFVALNEELKVRNERRDRKFLSLNYKMRKAENDKDDARRLKDLNERFKREGKK
ALKDIDDLPKDYEAPDFFLKEAEKMAADFVIFNSDQKINQANGLSEAKTESKNKY

Specific function: Involved in the cleavage of a C-terminal peptide of 11 residues from the precursor form of penicillin-binding protein 3 (PBP3). May be involved in protection of the bacterium from thermal and osmotic stresses [H]

COG id: COG0793

COG function: function code M; Periplasmic protease

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Periplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PDZ (DHR) domain [H]

Homologues:

Organism=Escherichia coli, GI1788134, Length=663, Percent_Identity=52.0361990950226, Blast_Score=662, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR005151
- InterPro:   IPR004447
- InterPro:   IPR020992 [H]

Pfam domain/function: PF11818 DUF3340; PF00595 PDZ; PF03572 Peptidase_S41 [H]

EC number: =3.4.21.102 [H]

Molecular weight: Translated: 78907; Mature: 78907

Theoretical pI: Translated: 8.08; Mature: 8.08

Prosite motif: PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFKMSKNVICYAWLSVCLSSAIPAFAVQPTLKPSDISIPAISEESQLATKRATTRLTQS
CCCCCCCCCHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
HYRKIKLDDDFSEKIFDRYIKNLDFNHNTFLQSDIDELRQKYGTKLDEQLNQGDLSAAFD
HCEEEECCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCHHHHCCCCCCHHHHH
IYDVMMKRRYERYTYALSLLDKEPDLNGQDQIEIDREKAAAPQTEADANKLWDARVKNDI
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEECHHHCCCCCCCCCHHHHHHHHHCCCE
INLKLKDKKWSEIKAKLTKRYNLAIRRLTQTKADDIVQIYLNAFAREIDPHTSYLSPRTA
EEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCCHH
KSFNESINLSLEGIGTTLQSEDDEISIKSLVPGAPAERSKKLHPGDKIIGVGQATGDIED
HHCCCCEEEEEEECCCCCCCCCCCEEHHHCCCCCCCHHCCCCCCCCCEEECCCCCCCHHH
VVGWRLEDLVEKIKGKKGTKVRLEIEPAKGGKSRIITLVRDKVRIEDQAAKLTFEKVSGK
HHCCCHHHHHHHHCCCCCCEEEEEEECCCCCCHHEEEEHHHHHHCCHHHHHEEHEECCCC
NIAVIKIPSFYIGLTEDVKKLLVKLENQKAEALIVDLRENGGGALTEAVALSGLFIADGP
EEEEEEECCEEECCHHHHHHHHHHHCCCCCEEEEEEEECCCCCHHHHHHHHCCEEECCCC
VVQVRDAYQRIRVHEDDDATQQYKGLLFVMINRYSASASEIFAAAMQDYRRGIIIGQNTF
EEHHHHHHHHCCCCCCCCHHHHHCCEEEEEEECCCCCHHHHHHHHHHHHHCCEEEECCCC
GKGTVQQSRSLNFIYDLDQSPLGVLQYTIQKFYRINGGSTQLKGVAADINFPEIIDSKEY
CCCCHHHCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCCCEEEEEEECCCCHHHCCCHHC
GEDKEDNALAWDKIPSASYMEVGNIDYIDNAVNILNEKHLARIAKDPEFVALNEELKVRN
CCCCCCCCEECCCCCCCCCEECCCCCHHHHHHHHHHHHHHHHHHCCCCEEEECHHHHHHH
ERRDRKFLSLNYKMRKAENDKDDARRLKDLNERFKREGKKALKDIDDLPKDYEAPDFFLK
HHHCCCEEEECEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHH
EAEKMAADFVIFNSDQKINQANGLSEAKTESKNKY
HHHHHHHCEEEECCCCCCHHHCCCCHHHHCCCCCC
>Mature Secondary Structure
MKFKMSKNVICYAWLSVCLSSAIPAFAVQPTLKPSDISIPAISEESQLATKRATTRLTQS
CCCCCCCCCHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
HYRKIKLDDDFSEKIFDRYIKNLDFNHNTFLQSDIDELRQKYGTKLDEQLNQGDLSAAFD
HCEEEECCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCHHHHCCCCCCHHHHH
IYDVMMKRRYERYTYALSLLDKEPDLNGQDQIEIDREKAAAPQTEADANKLWDARVKNDI
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEECHHHCCCCCCCCCHHHHHHHHHCCCE
INLKLKDKKWSEIKAKLTKRYNLAIRRLTQTKADDIVQIYLNAFAREIDPHTSYLSPRTA
EEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCCHH
KSFNESINLSLEGIGTTLQSEDDEISIKSLVPGAPAERSKKLHPGDKIIGVGQATGDIED
HHCCCCEEEEEEECCCCCCCCCCCEEHHHCCCCCCCHHCCCCCCCCCEEECCCCCCCHHH
VVGWRLEDLVEKIKGKKGTKVRLEIEPAKGGKSRIITLVRDKVRIEDQAAKLTFEKVSGK
HHCCCHHHHHHHHCCCCCCEEEEEEECCCCCCHHEEEEHHHHHHCCHHHHHEEHEECCCC
NIAVIKIPSFYIGLTEDVKKLLVKLENQKAEALIVDLRENGGGALTEAVALSGLFIADGP
EEEEEEECCEEECCHHHHHHHHHHHCCCCCEEEEEEEECCCCCHHHHHHHHCCEEECCCC
VVQVRDAYQRIRVHEDDDATQQYKGLLFVMINRYSASASEIFAAAMQDYRRGIIIGQNTF
EEHHHHHHHHCCCCCCCCHHHHHCCEEEEEEECCCCCHHHHHHHHHHHHHCCEEEECCCC
GKGTVQQSRSLNFIYDLDQSPLGVLQYTIQKFYRINGGSTQLKGVAADINFPEIIDSKEY
CCCCHHHCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCCCEEEEEEECCCCHHHCCCHHC
GEDKEDNALAWDKIPSASYMEVGNIDYIDNAVNILNEKHLARIAKDPEFVALNEELKVRN
CCCCCCCCEECCCCCCCCCEECCCCCHHHHHHHHHHHHHHHHHHCCCCEEEECHHHHHHH
ERRDRKFLSLNYKMRKAENDKDDARRLKDLNERFKREGKKALKDIDDLPKDYEAPDFFLK
HHHCCCEEEECEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHH
EAEKMAADFVIFNSDQKINQANGLSEAKTESKNKY
HHHHHHHCEEEECCCCCCHHHCCCCHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]