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The map label for this gene is asnC [H]

Identifier: 148827002

GI number: 148827002

Start: 243836

End: 245239

Strand: Direct

Name: asnC [H]

Synonym: CGSHiGG_01450

Alternate gene names: 148827002

Gene position: 243836-245239 (Clockwise)

Preceding gene: 148826995

Following gene: 148827003

Centisome position: 12.92

GC content: 40.1

Gene sequence:

>1404_bases
ATGTCTAAAGTGGCATCAATTGTTGATGTATTACAAGGGAAAGTGGCGATTGGTGAAACCGTCACTGTGCGTGGTTGGGT
TCGTACCCGTCGCGATTCTAAAGCAGGCTTATCTTTCTTAGCGGTTTATGACGGTTCTTGTTTTGATCCAATTCAAGCGA
TTATTAATAACGATATTGAAAATTACGAAAGCGAAATTTTACGTTTAACAACAGGCTGTTCTGTGATTGTAACCGGTAAG
GTCGTTGAATCACCTGCAGAAGGACAAGCGGTTGAATTACAAGCAGAAAAAGTGGAAGTGACAGGGTTTGTTGAAGATCC
AGATACTTACCCAATGGCAGCAAAACGCCACTCTATCGAATATTTACGCGAAGTGGCTCACTTACGTCCTCGTACCAATA
TTATTGGCGCGGTCGCGCGTGTTCGTCATTGCTTGTCTCAAGCAATTCACCGTTTCTTCCATGAGCAAGGTTTCTACTGG
GTGGCAACCCCATTAATTACTGCATCAGACACTGAAGGTGCGGGTGAAATGTTCCGTGTTTCTACACTTGATTTAGAAAA
TCTTCCACGTAGTGAAAATGGAAAAGTTGATTTCAGCCAAGATTTCTTCGGTAAAGAATCATTTTTAACGGTTTCAGGTC
AGTTAAACGGCGAAACCTATGCTTGTGCATTAAGCAAAATTTATACTTTTGGCCCAACATTCCGTGCAGAAAACTCGAAT
ACTACCCGTCACTTAGCGGAATTCTGGATGGTTGAACCCGAAGTTGCATTTGCAACTTTAGCGGATAACGCAAAACTTGC
AGAAGATATGTTGAAATACGTATTCCGTGCAGTATTAGCAGAGCGTAAAGATGACTTACAATTCTTTGAAAAACATGTAG
ATAAAGATGTTATTACTCGTTTAGAAAACTTTGTAAACTCAGATTTTGCGCAAATTGACTATACCGATGCCATTGATGTG
TTATTAAAATCTGGTAAGAAATTTGAATTCCCTGTTTCTTGGGGTATTGATCTTTCTTCTGAACACGAACGTTTCTTAGC
GGAAGAATATTTCAAATCACCAGTTGTGGTAAAAAACTATCCAAAAGACATTAAAGCATTCTATATGCGTTTAAATGATG
ATGGAAAAACTGTGGCAGCAATGGACGTGTTAGCTCCAGGAATTGGTGAAATCATCGGTGGTTCACAACGTGAAGAACGT
TTAGAGGTGCTTGATAAACGCATGGAAGAAATGGGATTAAATCCAGATGATTATTGGTGGTATCGCGATCTTCGTAAATA
CGGCAGTGTTCCACATTCTGGTTTTGGTCTTGGTTTTGAACGTTTAATCGTCTATGTAACTGGCGTGCAAAATATTCGTG
ATGTAATTCCATTCCCACGCGCGCCAAGAAATGCGAATTTCTAA

Upstream 100 bases:

>100_bases
CATAGCCCGCACCAACACTATATTTTTATGGAAAATTTCCTTTATTAAGGTAAACTGTCGGCAATTTTATGTGAATTACA
TTCAGTTACAGAGGTTTAAT

Downstream 100 bases:

>100_bases
TTCAATTTAACTTTAATATTGACCGCACTTACGCCAAAGTGCGGTCAATTTTTTCAGAATTTTAAGGAAAGTAAAATGGA
TAAAATTAAACAACTCTTTG

Product: asparaginyl-tRNA synthetase

Products: NA

Alternate protein names: Asparagine--tRNA ligase; AsnRS [H]

Number of amino acids: Translated: 467; Mature: 466

Protein sequence:

>467_residues
MSKVASIVDVLQGKVAIGETVTVRGWVRTRRDSKAGLSFLAVYDGSCFDPIQAIINNDIENYESEILRLTTGCSVIVTGK
VVESPAEGQAVELQAEKVEVTGFVEDPDTYPMAAKRHSIEYLREVAHLRPRTNIIGAVARVRHCLSQAIHRFFHEQGFYW
VATPLITASDTEGAGEMFRVSTLDLENLPRSENGKVDFSQDFFGKESFLTVSGQLNGETYACALSKIYTFGPTFRAENSN
TTRHLAEFWMVEPEVAFATLADNAKLAEDMLKYVFRAVLAERKDDLQFFEKHVDKDVITRLENFVNSDFAQIDYTDAIDV
LLKSGKKFEFPVSWGIDLSSEHERFLAEEYFKSPVVVKNYPKDIKAFYMRLNDDGKTVAAMDVLAPGIGEIIGGSQREER
LEVLDKRMEEMGLNPDDYWWYRDLRKYGSVPHSGFGLGFERLIVYVTGVQNIRDVIPFPRAPRNANF

Sequences:

>Translated_467_residues
MSKVASIVDVLQGKVAIGETVTVRGWVRTRRDSKAGLSFLAVYDGSCFDPIQAIINNDIENYESEILRLTTGCSVIVTGK
VVESPAEGQAVELQAEKVEVTGFVEDPDTYPMAAKRHSIEYLREVAHLRPRTNIIGAVARVRHCLSQAIHRFFHEQGFYW
VATPLITASDTEGAGEMFRVSTLDLENLPRSENGKVDFSQDFFGKESFLTVSGQLNGETYACALSKIYTFGPTFRAENSN
TTRHLAEFWMVEPEVAFATLADNAKLAEDMLKYVFRAVLAERKDDLQFFEKHVDKDVITRLENFVNSDFAQIDYTDAIDV
LLKSGKKFEFPVSWGIDLSSEHERFLAEEYFKSPVVVKNYPKDIKAFYMRLNDDGKTVAAMDVLAPGIGEIIGGSQREER
LEVLDKRMEEMGLNPDDYWWYRDLRKYGSVPHSGFGLGFERLIVYVTGVQNIRDVIPFPRAPRNANF
>Mature_466_residues
SKVASIVDVLQGKVAIGETVTVRGWVRTRRDSKAGLSFLAVYDGSCFDPIQAIINNDIENYESEILRLTTGCSVIVTGKV
VESPAEGQAVELQAEKVEVTGFVEDPDTYPMAAKRHSIEYLREVAHLRPRTNIIGAVARVRHCLSQAIHRFFHEQGFYWV
ATPLITASDTEGAGEMFRVSTLDLENLPRSENGKVDFSQDFFGKESFLTVSGQLNGETYACALSKIYTFGPTFRAENSNT
TRHLAEFWMVEPEVAFATLADNAKLAEDMLKYVFRAVLAERKDDLQFFEKHVDKDVITRLENFVNSDFAQIDYTDAIDVL
LKSGKKFEFPVSWGIDLSSEHERFLAEEYFKSPVVVKNYPKDIKAFYMRLNDDGKTVAAMDVLAPGIGEIIGGSQREERL
EVLDKRMEEMGLNPDDYWWYRDLRKYGSVPHSGFGLGFERLIVYVTGVQNIRDVIPFPRAPRNANF

Specific function: Unknown

COG id: COG0017

COG function: function code J; Aspartyl/asparaginyl-tRNA synthetases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI226491502, Length=464, Percent_Identity=42.4568965517241, Blast_Score=385, Evalue=1e-107,
Organism=Homo sapiens, GI4758762, Length=456, Percent_Identity=29.6052631578947, Blast_Score=194, Evalue=1e-49,
Organism=Homo sapiens, GI45439306, Length=343, Percent_Identity=27.1137026239067, Blast_Score=118, Evalue=1e-26,
Organism=Escherichia coli, GI1787161, Length=464, Percent_Identity=81.0344827586207, Blast_Score=810, Evalue=0.0,
Organism=Escherichia coli, GI1790571, Length=364, Percent_Identity=25, Blast_Score=68, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI71984122, Length=478, Percent_Identity=30.9623430962343, Blast_Score=196, Evalue=2e-50,
Organism=Caenorhabditis elegans, GI17556372, Length=428, Percent_Identity=30.8411214953271, Blast_Score=188, Evalue=5e-48,
Organism=Caenorhabditis elegans, GI17551876, Length=478, Percent_Identity=25.9414225941423, Blast_Score=110, Evalue=2e-24,
Organism=Saccharomyces cerevisiae, GI6319872, Length=472, Percent_Identity=36.6525423728814, Blast_Score=290, Evalue=3e-79,
Organism=Saccharomyces cerevisiae, GI6321807, Length=461, Percent_Identity=30.3687635574837, Blast_Score=198, Evalue=2e-51,
Organism=Saccharomyces cerevisiae, GI6323011, Length=501, Percent_Identity=24.9500998003992, Blast_Score=119, Evalue=7e-28,
Organism=Drosophila melanogaster, GI19922416, Length=469, Percent_Identity=35.8208955223881, Blast_Score=278, Evalue=6e-75,
Organism=Drosophila melanogaster, GI19921528, Length=469, Percent_Identity=29.2110874200426, Blast_Score=183, Evalue=2e-46,
Organism=Drosophila melanogaster, GI17136276, Length=488, Percent_Identity=25.8196721311475, Blast_Score=106, Evalue=3e-23,

Paralogues:

None

Copy number: 80 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004364
- InterPro:   IPR018150
- InterPro:   IPR006195
- InterPro:   IPR004522
- InterPro:   IPR002312
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR004365 [H]

Pfam domain/function: PF00152 tRNA-synt_2; PF01336 tRNA_anti [H]

EC number: =6.1.1.22 [H]

Molecular weight: Translated: 52775; Mature: 52644

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKVASIVDVLQGKVAIGETVTVRGWVRTRRDSKAGLSFLAVYDGSCFDPIQAIINNDIE
CCHHHHHHHHHCCCEEECCEEEEEHHHHHCCCCCCCCEEEEEECCCCHHHHHHHHCCCHH
NYESEILRLTTGCSVIVTGKVVESPAEGQAVELQAEKVEVTGFVEDPDTYPMAAKRHSIE
HHHHHHHHHCCCCEEEEECHHHCCCCCCCEEEEEEEEEEEEEEECCCCCCCCHHHHHHHH
YLREVAHLRPRTNIIGAVARVRHCLSQAIHRFFHEQGFYWVATPLITASDTEGAGEMFRV
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECEEEECCCCCCCCEEEE
STLDLENLPRSENGKVDFSQDFFGKESFLTVSGQLNGETYACALSKIYTFGPTFRAENSN
EEECHHHCCCCCCCCEECCHHHCCCCCEEEEEECCCCCHHHHHHHHHHHCCCCEECCCCC
TTRHLAEFWMVEPEVAFATLADNAKLAEDMLKYVFRAVLAERKDDLQFFEKHVDKDVITR
HHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCHHHHHH
LENFVNSDFAQIDYTDAIDVLLKSGKKFEFPVSWGIDLSSEHERFLAEEYFKSPVVVKNY
HHHHHCCCCCCCCCHHHHHHHHHCCCCEECCEEECCCCCCHHHHHHHHHHHCCCEEECCC
PKDIKAFYMRLNDDGKTVAAMDVLAPGIGEIIGGSQREERLEVLDKRMEEMGLNPDDYWW
CHHHHHHEEEECCCCCEEEHHHHHCCCHHHHHCCCCHHHHHHHHHHHHHHCCCCCCHHHH
YRDLRKYGSVPHSGFGLGFERLIVYVTGVQNIRDVIPFPRAPRNANF
HHHHHHHCCCCCCCCCCCHHHHHHHHHCHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
SKVASIVDVLQGKVAIGETVTVRGWVRTRRDSKAGLSFLAVYDGSCFDPIQAIINNDIE
CHHHHHHHHHCCCEEECCEEEEEHHHHHCCCCCCCCEEEEEECCCCHHHHHHHHCCCHH
NYESEILRLTTGCSVIVTGKVVESPAEGQAVELQAEKVEVTGFVEDPDTYPMAAKRHSIE
HHHHHHHHHCCCCEEEEECHHHCCCCCCCEEEEEEEEEEEEEEECCCCCCCCHHHHHHHH
YLREVAHLRPRTNIIGAVARVRHCLSQAIHRFFHEQGFYWVATPLITASDTEGAGEMFRV
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECEEEECCCCCCCCEEEE
STLDLENLPRSENGKVDFSQDFFGKESFLTVSGQLNGETYACALSKIYTFGPTFRAENSN
EEECHHHCCCCCCCCEECCHHHCCCCCEEEEEECCCCCHHHHHHHHHHHCCCCEECCCCC
TTRHLAEFWMVEPEVAFATLADNAKLAEDMLKYVFRAVLAERKDDLQFFEKHVDKDVITR
HHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCHHHHHH
LENFVNSDFAQIDYTDAIDVLLKSGKKFEFPVSWGIDLSSEHERFLAEEYFKSPVVVKNY
HHHHHCCCCCCCCCHHHHHHHHHCCCCEECCEEECCCCCCHHHHHHHHHHHCCCEEECCC
PKDIKAFYMRLNDDGKTVAAMDVLAPGIGEIIGGSQREERLEVLDKRMEEMGLNPDDYWW
CHHHHHHEEEECCCCCEEEHHHHHCCCHHHHHCCCCHHHHHHHHHHHHHHCCCCCCHHHH
YRDLRKYGSVPHSGFGLGFERLIVYVTGVQNIRDVIPFPRAPRNANF
HHHHHHHCCCCCCCCCCCHHHHHHHHHCHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA