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The map label for this gene is infC [H]

Identifier: 148826979

GI number: 148826979

Start: 221804

End: 222073

Strand: Reverse

Name: infC [H]

Synonym: CGSHiGG_01305

Alternate gene names: 148826979

Gene position: 222073-221804 (Counterclockwise)

Preceding gene: 148826980

Following gene: 148826978

Centisome position: 11.77

GC content: 42.22

Gene sequence:

>270_bases
GTGCAAGTTAAGGAAATTAAATTCCGCCCTGGCACAGACGAAGGTGACTATCAAGTTAAATTACGCAGCTTAATCCGTTT
CTTAGAAGACGGTGACAAAGCGAAAATTACCGTGCGTTTCCGCGGTCGTGAAATGGCTCATCAAGACATTGGTTTAGATG
TGTTAGAGCGCGTAAAAAATGATTTAGCTGAAATTTCAGTGGTTGAATCTGCACCAGGTAAATTAGAAGGTCGCCAAGCG
GTGATGGTGTTAGCACCGAAGAAAAAATAA

Upstream 100 bases:

>100_bases
CAAATGCAGAGCCGCCGGTTTGTCGAATTATGAACTACGGTAAATTCCTTTACGAAAAAAGTAAAACCGCTAAAGAACAA
AAAGAAAAAACAAAAAAGTT

Downstream 100 bases:

>100_bases
GAATTTTGCTGAGATTTCTCAGCAAATCTTTTTGTTTAAGTTTGACTTAAATGAAAAGACAACTGCATGTTGGGCACACT
ACGCAGCCTAACTGCTTTTG

Product: translation initiation factor IF-3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 89; Mature: 89

Protein sequence:

>89_residues
MQVKEIKFRPGTDEGDYQVKLRSLIRFLEDGDKAKITVRFRGREMAHQDIGLDVLERVKNDLAEISVVESAPGKLEGRQA
VMVLAPKKK

Sequences:

>Translated_89_residues
MQVKEIKFRPGTDEGDYQVKLRSLIRFLEDGDKAKITVRFRGREMAHQDIGLDVLERVKNDLAEISVVESAPGKLEGRQA
VMVLAPKKK
>Mature_89_residues
MQVKEIKFRPGTDEGDYQVKLRSLIRFLEDGDKAKITVRFRGREMAHQDIGLDVLERVKNDLAEISVVESAPGKLEGRQA
VMVLAPKKK

Specific function: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins [H]

COG id: COG0290

COG function: function code J; Translation initiation factor 3 (IF-3)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IF-3 family [H]

Homologues:

Organism=Escherichia coli, GI1788012, Length=89, Percent_Identity=82.0224719101124, Blast_Score=152, Evalue=5e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019813
- InterPro:   IPR001288
- InterPro:   IPR019815
- InterPro:   IPR019814 [H]

Pfam domain/function: PF00707 IF3_C; PF05198 IF3_N [H]

EC number: NA

Molecular weight: Translated: 10094; Mature: 10094

Theoretical pI: Translated: 10.06; Mature: 10.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQVKEIKFRPGTDEGDYQVKLRSLIRFLEDGDKAKITVRFRGREMAHQDIGLDVLERVKN
CCCCCEEECCCCCCCCEEEHHHHHHHHHCCCCCEEEEEEECCCCCCHHCCCHHHHHHHHH
DLAEISVVESAPGKLEGRQAVMVLAPKKK
HHHHEEEECCCCCCCCCCEEEEEEECCCC
>Mature Secondary Structure
MQVKEIKFRPGTDEGDYQVKLRSLIRFLEDGDKAKITVRFRGREMAHQDIGLDVLERVKN
CCCCCEEECCCCCCCCEEEHHHHHHHHHCCCCCEEEEEEECCCCCCHHCCCHHHHHHHHH
DLAEISVVESAPGKLEGRQAVMVLAPKKK
HHHHEEEECCCCCCCCCCEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11248100 [H]