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The map label for this gene is sbcB [H]

Identifier: 148826847

GI number: 148826847

Start: 113853

End: 115274

Strand: Direct

Name: sbcB [H]

Synonym: CGSHiGG_00585

Alternate gene names: 148826847

Gene position: 113853-115274 (Clockwise)

Preceding gene: 148826846

Following gene: 148826848

Centisome position: 6.03

GC content: 35.37

Gene sequence:

>1422_bases
ATGGCAAAAGATTTCAGCTTTTTTATTTACGATTATGAAAGTTTTGGTGTAAATCCAGCAACAGATCGCCCTGCGCAATT
TGCGGGTATTCGTACAGATGCTGATTTTAATATCATTGGCGAACCAATAATGTTTTATTGTAAACAAACCAACGATTATT
TACCGGCTCCTGAAGCCGTAATGGTCACAGGAATTACGCCGCAAGAATGTAATGAAAAGGGGCTTTCAGAGCCTGAATTC
TCCGCAAATATCTTAGCAGAATTTTCCCAACCCAATACTTGTGTCATGGGTTATAACAATATTCGCTATGATGATGAAAT
GACGCGTTATACGTTTTATCGAAATTTTATTGATCCTTATGAATACAGCTGGAAAAATGGGAATTCACGCTGGGATTTGT
TAGATTTAGTGCGAGCCTGTTATGCCTTGCGTCCAGAAGGGATTAATTGGGCTTATGACGATGATGGAATGCCAAGTTTC
CGCTTAGAAAAACTCACTAAAGCAAATGGTATTGAGCATGAAAATGCTCATGATGCCATGGCGGATGTATATGCAACTAT
TGCTATGGCGAAATTAATTAAAGAAAAACAACCTAAATTATTCCAATATTTCTTTGAAAATCGCGGTAAAAAAGAAATCG
AAAAATTAGTTGATACAGGCACAATGACACCTTTAGTGCATGTTTCTGGAATGCTAGGGAATTATCGTGGAAATTGCACT
TGGGTTGCACCTTTATCTTGGCATCCGACAAACCAAAACGCACTCATTGTTTGTGATTTAACTGGCGATATCGATAATTT
ATTAGCCAAAAGTGCGGATGAATTACGGACAGATTTATATACCAAAAAATCTGAATTAGAAGAAAGAGGAGTTTCATCTG
TTCCGTTAAAGCTTGTGCATATCAATAAATGTCCTATTTTAGCACCAGCTAAAACTTTGTTACCAGAAACAGCAAATCGA
TTGGGTATTGATCGACAATTATGCTTGGATAATCTTGCAAAATTACGAGCATCTTTTGATATTCGTGAAAAAGTGGCAGA
TATTTTTAATGAAGAACGTCAATTTGCATCGAATGATAATGTAGAAACTGAGTTATACAATGGCTTTTTTAGCAATGCTG
ATAAAAATAATATGGCTATTTTACGTAGTTTACCTGCAGAAAAATTATCTGAACATGGTTTAGCTTTTGAAGATAAACGT
ATCCTTGAATTATTGTTCCATTATCGCGCTCGTCATTTTTATAAAACCCTCACACGCGCTGAACAAATTAAATGGAAAAA
ATACCGACAGAATAAACTTGAAAAAAGTGCGGTAGAGTTTGAATCAAGTTTACAACGTTTAGCTGAGGAACATTCAGATA
ATTCTGAAAAACTATCTTTGCTACAACAAGTATATGAATATGGTATAAAATTACTAGGTTAG

Upstream 100 bases:

>100_bases
AAGAATTAGCAAGCTAAATTGGCTAGGCATTATTTTCAGTTTATCAGCTATTTTTTGCCTATATTATTTAGATAAAATTA
TCGCGTAAAAGAGAGTAGTC

Downstream 100 bases:

>100_bases
TCGATACGTTGTCACATTTTGTCAAAAAGCACGTTTTAATAAAAACGTGCTTTTTTTGTTGTTTTTCTGGGAAGAAAATA
TCCAAGAAATTCTCTAGATT

Product: exonuclease I

Products: NA

Alternate protein names: Exonuclease I; DNA deoxyribophosphodiesterase; dRPase [H]

Number of amino acids: Translated: 473; Mature: 472

Protein sequence:

>473_residues
MAKDFSFFIYDYESFGVNPATDRPAQFAGIRTDADFNIIGEPIMFYCKQTNDYLPAPEAVMVTGITPQECNEKGLSEPEF
SANILAEFSQPNTCVMGYNNIRYDDEMTRYTFYRNFIDPYEYSWKNGNSRWDLLDLVRACYALRPEGINWAYDDDGMPSF
RLEKLTKANGIEHENAHDAMADVYATIAMAKLIKEKQPKLFQYFFENRGKKEIEKLVDTGTMTPLVHVSGMLGNYRGNCT
WVAPLSWHPTNQNALIVCDLTGDIDNLLAKSADELRTDLYTKKSELEERGVSSVPLKLVHINKCPILAPAKTLLPETANR
LGIDRQLCLDNLAKLRASFDIREKVADIFNEERQFASNDNVETELYNGFFSNADKNNMAILRSLPAEKLSEHGLAFEDKR
ILELLFHYRARHFYKTLTRAEQIKWKKYRQNKLEKSAVEFESSLQRLAEEHSDNSEKLSLLQQVYEYGIKLLG

Sequences:

>Translated_473_residues
MAKDFSFFIYDYESFGVNPATDRPAQFAGIRTDADFNIIGEPIMFYCKQTNDYLPAPEAVMVTGITPQECNEKGLSEPEF
SANILAEFSQPNTCVMGYNNIRYDDEMTRYTFYRNFIDPYEYSWKNGNSRWDLLDLVRACYALRPEGINWAYDDDGMPSF
RLEKLTKANGIEHENAHDAMADVYATIAMAKLIKEKQPKLFQYFFENRGKKEIEKLVDTGTMTPLVHVSGMLGNYRGNCT
WVAPLSWHPTNQNALIVCDLTGDIDNLLAKSADELRTDLYTKKSELEERGVSSVPLKLVHINKCPILAPAKTLLPETANR
LGIDRQLCLDNLAKLRASFDIREKVADIFNEERQFASNDNVETELYNGFFSNADKNNMAILRSLPAEKLSEHGLAFEDKR
ILELLFHYRARHFYKTLTRAEQIKWKKYRQNKLEKSAVEFESSLQRLAEEHSDNSEKLSLLQQVYEYGIKLLG
>Mature_472_residues
AKDFSFFIYDYESFGVNPATDRPAQFAGIRTDADFNIIGEPIMFYCKQTNDYLPAPEAVMVTGITPQECNEKGLSEPEFS
ANILAEFSQPNTCVMGYNNIRYDDEMTRYTFYRNFIDPYEYSWKNGNSRWDLLDLVRACYALRPEGINWAYDDDGMPSFR
LEKLTKANGIEHENAHDAMADVYATIAMAKLIKEKQPKLFQYFFENRGKKEIEKLVDTGTMTPLVHVSGMLGNYRGNCTW
VAPLSWHPTNQNALIVCDLTGDIDNLLAKSADELRTDLYTKKSELEERGVSSVPLKLVHINKCPILAPAKTLLPETANRL
GIDRQLCLDNLAKLRASFDIREKVADIFNEERQFASNDNVETELYNGFFSNADKNNMAILRSLPAEKLSEHGLAFEDKRI
LELLFHYRARHFYKTLTRAEQIKWKKYRQNKLEKSAVEFESSLQRLAEEHSDNSEKLSLLQQVYEYGIKLLG

Specific function: Also functions as a DNA deoxyribophosphodiesterase that release deoxyribose-phosphate moieties following the cleavage DNA at an apurinic/apyrimidinic (AP) site by either an AP endonuclease AP lyase [H]

COG id: COG2925

COG function: function code L; Exonuclease I

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1788321, Length=468, Percent_Identity=56.6239316239316, Blast_Score=566, Evalue=1e-163,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013620
- InterPro:   IPR013520
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00929 Exonuc_X-T; PF08411 Exonuc_X-T_C [H]

EC number: =3.1.11.1 [H]

Molecular weight: Translated: 54388; Mature: 54257

Theoretical pI: Translated: 5.20; Mature: 5.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKDFSFFIYDYESFGVNPATDRPAQFAGIRTDADFNIIGEPIMFYCKQTNDYLPAPEAV
CCCCEEEEEEEHHHCCCCCCCCCCCHHCCEECCCCCCCCCCHHHHHHHCCCCCCCCCCEE
MVTGITPQECNEKGLSEPEFSANILAEFSQPNTCVMGYNNIRYDDEMTRYTFYRNFIDPY
EEECCCHHHHHHCCCCCCCCCHHHHHHCCCCCEEEECCCCCCCCCHHHHHHHHHHCCCCC
EYSWKNGNSRWDLLDLVRACYALRPEGINWAYDDDGMPSFRLEKLTKANGIEHENAHDAM
CCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCHHHHH
ADVYATIAMAKLIKEKQPKLFQYFFENRGKKEIEKLVDTGTMTPLVHVSGMLGNYRGNCT
HHHHHHHHHHHHHHHHCHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHCCCCCCEE
WVAPLSWHPTNQNALIVCDLTGDIDNLLAKSADELRTDLYTKKSELEERGVSSVPLKLVH
EEECEEECCCCCCEEEEEECCCCHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEE
INKCPILAPAKTLLPETANRLGIDRQLCLDNLAKLRASFDIREKVADIFNEERQFASNDN
ECCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
VETELYNGFFSNADKNNMAILRSLPAEKLSEHGLAFEDKRILELLFHYRARHFYKTLTRA
CCHHHHHHHHCCCCCCCHHHHHHCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
EQIKWKKYRQNKLEKSAVEFESSLQRLAEEHSDNSEKLSLLQQVYEYGIKLLG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHEECC
>Mature Secondary Structure 
AKDFSFFIYDYESFGVNPATDRPAQFAGIRTDADFNIIGEPIMFYCKQTNDYLPAPEAV
CCCEEEEEEEHHHCCCCCCCCCCCHHCCEECCCCCCCCCCHHHHHHHCCCCCCCCCCEE
MVTGITPQECNEKGLSEPEFSANILAEFSQPNTCVMGYNNIRYDDEMTRYTFYRNFIDPY
EEECCCHHHHHHCCCCCCCCCHHHHHHCCCCCEEEECCCCCCCCCHHHHHHHHHHCCCCC
EYSWKNGNSRWDLLDLVRACYALRPEGINWAYDDDGMPSFRLEKLTKANGIEHENAHDAM
CCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCHHHHH
ADVYATIAMAKLIKEKQPKLFQYFFENRGKKEIEKLVDTGTMTPLVHVSGMLGNYRGNCT
HHHHHHHHHHHHHHHHCHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHCCCCCCEE
WVAPLSWHPTNQNALIVCDLTGDIDNLLAKSADELRTDLYTKKSELEERGVSSVPLKLVH
EEECEEECCCCCCEEEEEECCCCHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEE
INKCPILAPAKTLLPETANRLGIDRQLCLDNLAKLRASFDIREKVADIFNEERQFASNDN
ECCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
VETELYNGFFSNADKNNMAILRSLPAEKLSEHGLAFEDKRILELLFHYRARHFYKTLTRA
CCHHHHHHHHCCCCCCCHHHHHHCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
EQIKWKKYRQNKLEKSAVEFESSLQRLAEEHSDNSEKLSLLQQVYEYGIKLLG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]