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The map label for this gene is plsC [H]

Identifier: 148826623

GI number: 148826623

Start: 1663518

End: 1664240

Strand: Direct

Name: plsC [H]

Synonym: CGSHiEE_08450

Alternate gene names: 148826623

Gene position: 1663518-1664240 (Clockwise)

Preceding gene: 148826621

Following gene: 148826624

Centisome position: 91.75

GC content: 37.9

Gene sequence:

>723_bases
ATGTTAAAACTACTTCGAATTTTCCTCGTATTAATCTGCTGTATTCTAATTTGTGTACTGGGTACGATTTATTCTTTTAT
CCGCTTTAAAAATCCAAGCAACGTAGGCATTGTTGCTCGTTGGTTTGGACGCTTATATCCACTTTTTGGCTTAAAGGTAG
AACATCGTATTCCTCAAGATCAGAAGCAAATTAGCCGCGCTATTTATATCGGTAATCATCAAAATAATTATGATATGGTA
ACAATCTCTTATATGGTGCAACCTCGTACAGTAAGCGTGGGTAAAAAAAGTTTAATTTGGATCCCCTTCTTCGGCATTTT
ATATTGGGTAACGGGCAATATTTTCTTGGATAGAGAAAACCGCACAAAAGCACACAGTACAATGTCGCAACTCGCACAAA
GAATTAATGAAGATAATTTATCTATTTGGATGTTCCCAGAAGGCACTCGCAGTCGTGGCCGCAGTTTATTACCCTTTAAA
ACGGGTGCATTTCATGCGGCAATTTCAGCAGGTGTACCAATTATTCCTGTGGTGTGTTCAACCACCCATAACAAAATTAA
TTTAAATCGTTGGGATAATGGCAAAGTGATTTGCGAAATAATGGAGCCGATTGATGTTTCAGGCTATACCAAAGACAATG
TTCGAGATCTTGCGGCTTATTGTCATGATCTAATGGAAAAACGCATTGCCGAACTTGATGAAGAGATAGCAAAAGGAAAC
TAA

Upstream 100 bases:

>100_bases
ATAGCTATGTTTCATAAAAATTCCACGATTTTTGTTTAGATTAGCACATATTGAGATTGAATTTGCTATACTTCAACGAA
ATTTTATATAGGACATCCTT

Downstream 100 bases:

>100_bases
AATGCCACGCCTGTCTCGCCGTCAATTATTAAAAACAGCTGCAATTTCTACCGCACTTTCCACAGTGCCAGCACCATTGT
TAGCGGCAAGCCGTGAAAAA

Product: 1-acyl-sn-glycerol-3-phosphate acyltransferase

Products: NA

Alternate protein names: 1-AGP acyltransferase; 1-AGPAT; Lysophosphatidic acid acyltransferase; LPAAT [H]

Number of amino acids: Translated: 240; Mature: 240

Protein sequence:

>240_residues
MLKLLRIFLVLICCILICVLGTIYSFIRFKNPSNVGIVARWFGRLYPLFGLKVEHRIPQDQKQISRAIYIGNHQNNYDMV
TISYMVQPRTVSVGKKSLIWIPFFGILYWVTGNIFLDRENRTKAHSTMSQLAQRINEDNLSIWMFPEGTRSRGRSLLPFK
TGAFHAAISAGVPIIPVVCSTTHNKINLNRWDNGKVICEIMEPIDVSGYTKDNVRDLAAYCHDLMEKRIAELDEEIAKGN

Sequences:

>Translated_240_residues
MLKLLRIFLVLICCILICVLGTIYSFIRFKNPSNVGIVARWFGRLYPLFGLKVEHRIPQDQKQISRAIYIGNHQNNYDMV
TISYMVQPRTVSVGKKSLIWIPFFGILYWVTGNIFLDRENRTKAHSTMSQLAQRINEDNLSIWMFPEGTRSRGRSLLPFK
TGAFHAAISAGVPIIPVVCSTTHNKINLNRWDNGKVICEIMEPIDVSGYTKDNVRDLAAYCHDLMEKRIAELDEEIAKGN
>Mature_240_residues
MLKLLRIFLVLICCILICVLGTIYSFIRFKNPSNVGIVARWFGRLYPLFGLKVEHRIPQDQKQISRAIYIGNHQNNYDMV
TISYMVQPRTVSVGKKSLIWIPFFGILYWVTGNIFLDRENRTKAHSTMSQLAQRINEDNLSIWMFPEGTRSRGRSLLPFK
TGAFHAAISAGVPIIPVVCSTTHNKINLNRWDNGKVICEIMEPIDVSGYTKDNVRDLAAYCHDLMEKRIAELDEEIAKGN

Specific function: Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating acyl moiety at the 2 position [H]

COG id: COG0204

COG function: function code I; 1-acyl-sn-glycerol-3-phosphate acyltransferase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI6041665, Length=225, Percent_Identity=30.6666666666667, Blast_Score=131, Evalue=6e-31,
Organism=Homo sapiens, GI5453718, Length=210, Percent_Identity=32.3809523809524, Blast_Score=125, Evalue=4e-29,
Organism=Homo sapiens, GI15100175, Length=210, Percent_Identity=32.3809523809524, Blast_Score=125, Evalue=4e-29,
Organism=Escherichia coli, GI1789395, Length=238, Percent_Identity=62.6050420168067, Blast_Score=317, Evalue=4e-88,
Organism=Caenorhabditis elegans, GI17564032, Length=177, Percent_Identity=33.8983050847458, Blast_Score=117, Evalue=7e-27,
Organism=Caenorhabditis elegans, GI17568319, Length=234, Percent_Identity=29.4871794871795, Blast_Score=105, Evalue=1e-23,
Organism=Saccharomyces cerevisiae, GI6320151, Length=236, Percent_Identity=31.3559322033898, Blast_Score=115, Evalue=4e-27,
Organism=Drosophila melanogaster, GI281364648, Length=234, Percent_Identity=29.9145299145299, Blast_Score=124, Evalue=5e-29,
Organism=Drosophila melanogaster, GI24582856, Length=234, Percent_Identity=29.9145299145299, Blast_Score=124, Evalue=5e-29,
Organism=Drosophila melanogaster, GI24582854, Length=234, Percent_Identity=29.9145299145299, Blast_Score=124, Evalue=5e-29,
Organism=Drosophila melanogaster, GI24641614, Length=185, Percent_Identity=32.4324324324324, Blast_Score=111, Evalue=4e-25,
Organism=Drosophila melanogaster, GI24641612, Length=185, Percent_Identity=32.4324324324324, Blast_Score=111, Evalue=4e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002123
- InterPro:   IPR004552 [H]

Pfam domain/function: PF01553 Acyltransferase [H]

EC number: =2.3.1.51 [H]

Molecular weight: Translated: 27479; Mature: 27479

Theoretical pI: Translated: 9.57; Mature: 9.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKLLRIFLVLICCILICVLGTIYSFIRFKNPSNVGIVARWFGRLYPLFGLKVEHRIPQD
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCEECCCCCHH
QKQISRAIYIGNHQNNYDMVTISYMVQPRTVSVGKKSLIWIPFFGILYWVTGNIFLDREN
HHHHHHEEEECCCCCCCEEEEEEEEECCEEECCCCCEEEEHHHHHHHHHHHCCEEEECCC
RTKAHSTMSQLAQRINEDNLSIWMFPEGTRSRGRSLLPFKTGAFHAAISAGVPIIPVVCS
CHHHHHHHHHHHHHCCCCCCEEEEECCCHHHCCCEECCCCCCHHHHHHHCCCCEEEEEEC
TTHNKINLNRWDNGKVICEIMEPIDVSGYTKDNVRDLAAYCHDLMEKRIAELDEEIAKGN
CCCCEEEEEECCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLKLLRIFLVLICCILICVLGTIYSFIRFKNPSNVGIVARWFGRLYPLFGLKVEHRIPQD
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCEECCCCCHH
QKQISRAIYIGNHQNNYDMVTISYMVQPRTVSVGKKSLIWIPFFGILYWVTGNIFLDREN
HHHHHHEEEECCCCCCCEEEEEEEEECCEEECCCCCEEEEHHHHHHHHHHHCCEEEECCC
RTKAHSTMSQLAQRINEDNLSIWMFPEGTRSRGRSLLPFKTGAFHAAISAGVPIIPVVCS
CHHHHHHHHHHHHHCCCCCCEEEEECCCHHHCCCEECCCCCCHHHHHHHCCCCEEEEEEC
TTHNKINLNRWDNGKVICEIMEPIDVSGYTKDNVRDLAAYCHDLMEKRIAELDEEIAKGN
CCCCEEEEEECCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]