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The map label for this gene is lsrE [H]

Identifier: 148826586

GI number: 148826586

Start: 1619149

End: 1619841

Strand: Direct

Name: lsrE [H]

Synonym: CGSHiEE_08235

Alternate gene names: 148826586

Gene position: 1619149-1619841 (Clockwise)

Preceding gene: 148826585

Following gene: 148826590

Centisome position: 89.31

GC content: 36.08

Gene sequence:

>693_bases
ATGAACGCAGAAAAAGTGCGATTGATTTCAGCATTAAAATCACAGCCAATCAGTGTAGGAATATTGGCGTCCAATTGGCT
TAAATTTTCAAAAACACTCAACGTATTAAGCCAAAACCAACTCCGCCTCCTGCATTTTGATATTGCTGACGGGCAATTTT
CCCCTTTTTTCACTGTGGGAAGTATGGCGATACAGCAGTTTCCTAACACATTTATAAAAGATGTGCATTTAATGGTAAAA
GATCAATTTAACGTTGTTAAAAAATGTGTTGCCGCCGGTGCGGATATTATGACCCTACAAGTTGAAAATACCGTTGATCT
AGACAACACATTACAATGGTTAAAAACGCAAAAAACGATATTATGTGGCTTGGCTATTTGTCCTAATACACCTTTAGAAT
TACTTTATCCCTATTTACCGGATATTGATTTAATCCAAATCTTAACATTGGATCCAAGAACTGGGGAAAAAGCTAATCTT
GATCAAATAACCGAACGATTAATCCAATTACTTAACCAACTTCATGATTCAGGGCAGGAAAAACTCATCTCTATTGATGG
CTCAATGACATTTGAATTGGCTTCACATTTGAAAAAATATGAGATCGATTGGGTTGTATCGGGTAGTGCTTTGTTTTCAT
CGGATTCCTTTGAAAAGACCTTGATAGAATGGAAAAAAATGCTGTCCCATTAA

Upstream 100 bases:

>100_bases
CGGAACATTACCAACGTTGTGTGAAAGAACTAGAGCCCTTAATGACGACACATCGGAGCAAAAAAATCTTTGAATGGGTT
TTTCCTGAGTAAATTGAAGC

Downstream 100 bases:

>100_bases
TACAAAAATACGGTTGTTTTCCACATTGTTTCAAAATCAAAACACAATGGGGAAACAACCGCACTTTTCAATCAACACCT
AAACTCGGTTATCAATCAAG

Product: ribulose-phosphate 3-epimerase

Products: D-Xylulose 5-phosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 230; Mature: 230

Protein sequence:

>230_residues
MNAEKVRLISALKSQPISVGILASNWLKFSKTLNVLSQNQLRLLHFDIADGQFSPFFTVGSMAIQQFPNTFIKDVHLMVK
DQFNVVKKCVAAGADIMTLQVENTVDLDNTLQWLKTQKTILCGLAICPNTPLELLYPYLPDIDLIQILTLDPRTGEKANL
DQITERLIQLLNQLHDSGQEKLISIDGSMTFELASHLKKYEIDWVVSGSALFSSDSFEKTLIEWKKMLSH

Sequences:

>Translated_230_residues
MNAEKVRLISALKSQPISVGILASNWLKFSKTLNVLSQNQLRLLHFDIADGQFSPFFTVGSMAIQQFPNTFIKDVHLMVK
DQFNVVKKCVAAGADIMTLQVENTVDLDNTLQWLKTQKTILCGLAICPNTPLELLYPYLPDIDLIQILTLDPRTGEKANL
DQITERLIQLLNQLHDSGQEKLISIDGSMTFELASHLKKYEIDWVVSGSALFSSDSFEKTLIEWKKMLSH
>Mature_230_residues
MNAEKVRLISALKSQPISVGILASNWLKFSKTLNVLSQNQLRLLHFDIADGQFSPFFTVGSMAIQQFPNTFIKDVHLMVK
DQFNVVKKCVAAGADIMTLQVENTVDLDNTLQWLKTQKTILCGLAICPNTPLELLYPYLPDIDLIQILTLDPRTGEKANL
DQITERLIQLLNQLHDSGQEKLISIDGSMTFELASHLKKYEIDWVVSGSALFSSDSFEKTLIEWKKMLSH

Specific function: Unknown

COG id: COG0036

COG function: function code G; Pentose-5-phosphate-3-epimerase

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribulose-phosphate 3-epimerase family [H]

Homologues:

Organism=Homo sapiens, GI40385883, Length=176, Percent_Identity=26.7045454545455, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1789788, Length=221, Percent_Identity=27.1493212669683, Blast_Score=98, Evalue=4e-22,
Organism=Escherichia coli, GI1790523, Length=200, Percent_Identity=27, Blast_Score=69, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR000056
- InterPro:   IPR011060 [H]

Pfam domain/function: PF00834 Ribul_P_3_epim [H]

EC number: 5.1.3.1 [C]

Molecular weight: Translated: 25951; Mature: 25951

Theoretical pI: Translated: 6.01; Mature: 6.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAEKVRLISALKSQPISVGILASNWLKFSKTLNVLSQNQLRLLHFDIADGQFSPFFTVG
CCCHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCHHHHH
SMAIQQFPNTFIKDVHLMVKDQFNVVKKCVAAGADIMTLQVENTVDLDNTLQWLKTQKTI
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHH
LCGLAICPNTPLELLYPYLPDIDLIQILTLDPRTGEKANLDQITERLIQLLNQLHDSGQE
HEEEEECCCCCHHHHHCCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCC
KLISIDGSMTFELASHLKKYEIDWVVSGSALFSSDSFEKTLIEWKKMLSH
EEEEECCCCHHHHHHHHHHEEEEEEEECCCEECCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MNAEKVRLISALKSQPISVGILASNWLKFSKTLNVLSQNQLRLLHFDIADGQFSPFFTVG
CCCHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCHHHHH
SMAIQQFPNTFIKDVHLMVKDQFNVVKKCVAAGADIMTLQVENTVDLDNTLQWLKTQKTI
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHH
LCGLAICPNTPLELLYPYLPDIDLIQILTLDPRTGEKANLDQITERLIQLLNQLHDSGQE
HEEEEECCCCCHHHHHCCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCC
KLISIDGSMTFELASHLKKYEIDWVVSGSALFSSDSFEKTLIEWKKMLSH
EEEEECCCCHHHHHHHHHHEEEEEEEECCCEECCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): 78000 [C]

Specific activity: NA

Km value (mM): 15 {D-ribulose} 2.4 {D-ribulose-5-phosphate}} [C]

Substrates: D-Ribulose 5-phosphate [C]

Specific reaction: D-Ribulose 5-phosphate <==> D-Xylulose 5-phosphate [C]

General reaction: Epimerization [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA