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The map label for this gene is lsrC [H]

Identifier: 148826581

GI number: 148826581

Start: 1614802

End: 1615782

Strand: Direct

Name: lsrC [H]

Synonym: CGSHiEE_08210

Alternate gene names: 148826581

Gene position: 1614802-1615782 (Clockwise)

Preceding gene: 148826551

Following gene: 148826582

Centisome position: 89.07

GC content: 41.49

Gene sequence:

>981_bases
ATGTGGAAACTCATTCAAGATAATCGCGAATTGACCATTTTAATTGCTATCGGTTTGCTGTTTACCCTATTAGGATTTGT
TGGTGCCGGATTTCATTTGCAAACACTCATGATGATTTTTAATTCAGCTCAAATCGTGATTTTACTGGCAATTGGCGCAA
CCTTTGTCATTTTAACGCGAAATATTGATGTATCAGTCGGTTCCACAATGGGATTAAGTGCAGTTATTGTCGGAAGTCTG
CTCAATGCCGGATTAGGACTTGCAAGTGCCTTTACCCTCACTTTACTTTGCGGTTTAACCGCCGGATTACTGAATGGCGT
ATTAGTTACGCTCTTACGAATCCCTGCTATTGTGGCAACCTTGGGAACATTAGGTTTATATAAAGGAATGATGTTATTGA
TCACAGGTGGGAAATGGATTGAAGGTTTACCGCAAGACCTAAAAACCTTATCGGCCCCGATTTTTCTAAATATCTCCGTT
ATTGGCTGGATATTAATTCTCATCATTCTAGCCACTTACTATTTCTTAACAAAATGCTCAACCGGACGGTATTTTTATGC
TGTGGGAGATAATTTACAAGGTGCAATGCAACTTGGTGTACCGATTAATCGGGTCAGAATTATTGCCTTTGCAATAAATG
GCTTAATGGCTGCCATCGCCGGTATTGTGTTCACGTCTCAAATCGGATTCGTGCCAAACTCAACCGGAAATGGGCTAGAG
ATGAAAGCGATAGCCGCTTGCGTATTGGGCGGAATTAGTTTGTTAGGTGGTGCCGGTAACTTAATCGGTGCGGTGCTTGG
CGCCTATTTCCTCATTCAAATTGATTCTATATTGGTTCTTCTTAAAGTACCGGCTTACTGGAATAACTTCGTTGCGGGTA
TCGTGCTTTTAGTCGTCTTGGTCTTTGACGGTCGGATCCGAGTCATGATTTCTCACAATCTCAAATTACAACGCTATGCA
CGATTTTTAAAAGACGACTAG

Upstream 100 bases:

>100_bases
CATGACGGACAAATCAGCGAATCATTATGCGGAGAACAAATTAACACTAACAACATTATGCAAATGGCATTTGGTAGCAA
TGGGTATTAAGGAGAAAAAT

Downstream 100 bases:

>100_bases
CCCCATTTGTTTATCAAAGTGCGGTCATTAAAGGAGAAAGATGATGTTGACGATAAAAAAACATGCTTGGGAATTGACAT
TGCTACTACTATTAATACTT

Product: hypothetical protein

Products: NA

Alternate protein names: AI-2 import system permease protein lsrC [H]

Number of amino acids: Translated: 326; Mature: 326

Protein sequence:

>326_residues
MWKLIQDNRELTILIAIGLLFTLLGFVGAGFHLQTLMMIFNSAQIVILLAIGATFVILTRNIDVSVGSTMGLSAVIVGSL
LNAGLGLASAFTLTLLCGLTAGLLNGVLVTLLRIPAIVATLGTLGLYKGMMLLITGGKWIEGLPQDLKTLSAPIFLNISV
IGWILILIILATYYFLTKCSTGRYFYAVGDNLQGAMQLGVPINRVRIIAFAINGLMAAIAGIVFTSQIGFVPNSTGNGLE
MKAIAACVLGGISLLGGAGNLIGAVLGAYFLIQIDSILVLLKVPAYWNNFVAGIVLLVVLVFDGRIRVMISHNLKLQRYA
RFLKDD

Sequences:

>Translated_326_residues
MWKLIQDNRELTILIAIGLLFTLLGFVGAGFHLQTLMMIFNSAQIVILLAIGATFVILTRNIDVSVGSTMGLSAVIVGSL
LNAGLGLASAFTLTLLCGLTAGLLNGVLVTLLRIPAIVATLGTLGLYKGMMLLITGGKWIEGLPQDLKTLSAPIFLNISV
IGWILILIILATYYFLTKCSTGRYFYAVGDNLQGAMQLGVPINRVRIIAFAINGLMAAIAGIVFTSQIGFVPNSTGNGLE
MKAIAACVLGGISLLGGAGNLIGAVLGAYFLIQIDSILVLLKVPAYWNNFVAGIVLLVVLVFDGRIRVMISHNLKLQRYA
RFLKDD
>Mature_326_residues
MWKLIQDNRELTILIAIGLLFTLLGFVGAGFHLQTLMMIFNSAQIVILLAIGATFVILTRNIDVSVGSTMGLSAVIVGSL
LNAGLGLASAFTLTLLCGLTAGLLNGVLVTLLRIPAIVATLGTLGLYKGMMLLITGGKWIEGLPQDLKTLSAPIFLNISV
IGWILILIILATYYFLTKCSTGRYFYAVGDNLQGAMQLGVPINRVRIIAFAINGLMAAIAGIVFTSQIGFVPNSTGNGLE
MKAIAACVLGGISLLGGAGNLIGAVLGAYFLIQIDSILVLLKVPAYWNNFVAGIVLLVVLVFDGRIRVMISHNLKLQRYA
RFLKDD

Specific function: Part of the ABC transporter complex lsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG1172

COG function: function code G; Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. AraH/rbsC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787793, Length=324, Percent_Identity=65.1234567901235, Blast_Score=370, Evalue=1e-104,
Organism=Escherichia coli, GI1790191, Length=281, Percent_Identity=31.6725978647687, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI1788896, Length=291, Percent_Identity=33.3333333333333, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI1789992, Length=130, Percent_Identity=42.3076923076923, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI1790524, Length=271, Percent_Identity=28.7822878228782, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI145693152, Length=256, Percent_Identity=30.46875, Blast_Score=101, Evalue=8e-23,
Organism=Escherichia coli, GI1787794, Length=292, Percent_Identity=31.5068493150685, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI145693214, Length=255, Percent_Identity=36.8627450980392, Blast_Score=91, Evalue=7e-20,
Organism=Escherichia coli, GI87082395, Length=320, Percent_Identity=27.1875, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1788471, Length=281, Percent_Identity=27.0462633451957, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001851 [H]

Pfam domain/function: PF02653 BPD_transp_2 [H]

EC number: NA

Molecular weight: Translated: 34672; Mature: 34672

Theoretical pI: Translated: 9.91; Mature: 9.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWKLIQDNRELTILIAIGLLFTLLGFVGAGFHLQTLMMIFNSAQIVILLAIGATFVILTR
CCCCCCCCCCEEEHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHEEEEECCCEEEEEEE
NIDVSVGSTMGLSAVIVGSLLNAGLGLASAFTLTLLCGLTAGLLNGVLVTLLRIPAIVAT
CCCEECCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGTLGLYKGMMLLITGGKWIEGLPQDLKTLSAPIFLNISVIGWILILIILATYYFLTKCS
HHHHHHHCCEEEEEECCHHHHCCHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHCC
TGRYFYAVGDNLQGAMQLGVPINRVRIIAFAINGLMAAIAGIVFTSQIGFVPNSTGNGLE
CCCEEEEECCCCCCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCH
MKAIAACVLGGISLLGGAGNLIGAVLGAYFLIQIDSILVLLKVPAYWNNFVAGIVLLVVL
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
VFDGRIRVMISHNLKLQRYARFLKDD
HHCCCEEEEEECCCCHHHHHHHHCCC
>Mature Secondary Structure
MWKLIQDNRELTILIAIGLLFTLLGFVGAGFHLQTLMMIFNSAQIVILLAIGATFVILTR
CCCCCCCCCCEEEHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHEEEEECCCEEEEEEE
NIDVSVGSTMGLSAVIVGSLLNAGLGLASAFTLTLLCGLTAGLLNGVLVTLLRIPAIVAT
CCCEECCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGTLGLYKGMMLLITGGKWIEGLPQDLKTLSAPIFLNISVIGWILILIILATYYFLTKCS
HHHHHHHCCEEEEEECCHHHHCCHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHCC
TGRYFYAVGDNLQGAMQLGVPINRVRIIAFAINGLMAAIAGIVFTSQIGFVPNSTGNGLE
CCCEEEEECCCCCCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCH
MKAIAACVLGGISLLGGAGNLIGAVLGAYFLIQIDSILVLLKVPAYWNNFVAGIVLLVVL
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
VFDGRIRVMISHNLKLQRYARFLKDD
HHCCCEEEEEECCCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 14528314 [H]