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The map label for this gene is frdD [H]

Identifier: 148826523

GI number: 148826523

Start: 1566898

End: 1567242

Strand: Direct

Name: frdD [H]

Synonym: CGSHiEE_07900

Alternate gene names: 148826523

Gene position: 1566898-1567242 (Clockwise)

Preceding gene: 148826522

Following gene: 148826535

Centisome position: 86.42

GC content: 38.84

Gene sequence:

>345_bases
ATGGTTGATCAAAATCCAAAACGCTCCGGCGAACCGCCAGTATGGTTAATGTTCGGTGCAGGCGGCACAGTGAGTGCAAT
TTTCTTCCCTGTCGTTATTTTAATTATCGGTTTGTTATTACCATTTGGTTTAGTCGATGCGCATAATTTAATTACTTTTG
CTTATTCTTGGATTGGTAAATTAGTTATTTTAGTGCTTACTATTTTCCCAATGTGGTGTGGTTTACACCGTATTCATCAC
GGTATGCACGATCTTAAAGTGCATGTGCCAGCTGGTGGATTTATCTTTTACGGTTTAGCCACAATTTATACCGTTTGGGT
GTTATTTGCGGTAATAAACCTGTAA

Upstream 100 bases:

>100_bases
ACGCTTACCACACCGCGTTATAAGAAATGCACTTTGGGCGGTAACCGCATTAATTAGCGTGATTGCGTTAGTTTTAGTTT
ATATTTAAGGGAGAGAAAAA

Downstream 100 bases:

>100_bases
TAAAAACGCTATAAATAAAAAACGAGTCTAAGACTTCGTTTTTTTATTTTATGTATTAAGTAAATATTGTTTAGTTTGTT
TTACTTTAGAAATTCGATTG

Product: fumarate reductase subunit D

Products: fumarate; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 114; Mature: 114

Protein sequence:

>114_residues
MVDQNPKRSGEPPVWLMFGAGGTVSAIFFPVVILIIGLLLPFGLVDAHNLITFAYSWIGKLVILVLTIFPMWCGLHRIHH
GMHDLKVHVPAGGFIFYGLATIYTVWVLFAVINL

Sequences:

>Translated_114_residues
MVDQNPKRSGEPPVWLMFGAGGTVSAIFFPVVILIIGLLLPFGLVDAHNLITFAYSWIGKLVILVLTIFPMWCGLHRIHH
GMHDLKVHVPAGGFIFYGLATIYTVWVLFAVINL
>Mature_114_residues
MVDQNPKRSGEPPVWLMFGAGGTVSAIFFPVVILIIGLLLPFGLVDAHNLITFAYSWIGKLVILVLTIFPMWCGLHRIHH
GMHDLKVHVPAGGFIFYGLATIYTVWVLFAVINL

Specific function: Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane [H]

COG id: COG3080

COG function: function code C; Fumarate reductase subunit D

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the frdD family [H]

Homologues:

Organism=Escherichia coli, GI1790594, Length=119, Percent_Identity=51.2605042016807, Blast_Score=125, Evalue=5e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003418
- ProDom:   PD015693 [H]

Pfam domain/function: PF02313 Fumarate_red_D [H]

EC number: 1.3.99.1

Molecular weight: Translated: 12642; Mature: 12642

Theoretical pI: Translated: 8.52; Mature: 8.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVDQNPKRSGEPPVWLMFGAGGTVSAIFFPVVILIIGLLLPFGLVDAHNLITFAYSWIGK
CCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LVILVLTIFPMWCGLHRIHHGMHDLKVHVPAGGFIFYGLATIYTVWVLFAVINL
HHHHHHHHHHHHHHHHHHHCCHHHEEEECCCCHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MVDQNPKRSGEPPVWLMFGAGGTVSAIFFPVVILIIGLLLPFGLVDAHNLITFAYSWIGK
CCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LVILVLTIFPMWCGLHRIHHGMHDLKVHVPAGGFIFYGLATIYTVWVLFAVINL
HHHHHHHHHHHHHHHHHHHCCHHHEEEECCCCHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: succinate; acceptor

Specific reaction: succinate + acceptor = fumarate + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA