Click here to switch to the map view.

The map label for this gene is nrfX [H]

Identifier: 148826415

GI number: 148826415

Start: 1449888

End: 1450418

Strand: Direct

Name: nrfX [H]

Synonym: CGSHiEE_07290

Alternate gene names: 148826415

Gene position: 1449888-1450418 (Clockwise)

Preceding gene: 148826414

Following gene: 148826416

Centisome position: 79.97

GC content: 38.42

Gene sequence:

>531_bases
ATGAACAAAAAACTTATCTTTTTTACACCGCTCTTTGTGCTTTTAGGCGTGTGTATATTATTAATTGCAGGGTTAAATCA
AGATCCGAAAAAAATTGCTTCGGCTTTAATTGATAAACCTGTTCCAGAGTTTTATCAGGCTAATTTACATGAGCCATCAC
AAATCGTAAGCCCGAAAGAGTTTCCTAAACAGCCATTTTTATTAAATGTGTGGGGAAGTTGGTGTGGTTATTGCAAAGAA
GAACATCCTCTGCTAATTGAGATTGCAAAAACATTGCCTATTGTGGGCGTGGATTACCGTGATAATCCGCAAAATGGCAT
TGAAATGCTTAAGCGAATGGGCAATCCGTTCGTCTTGACCATTGATGATAGTCATGGGAAATTGGGATTAAAATTGGGCG
TGGATGGCGCGCCAGAAACTTACCTTGTGGATGAAAATGGTGTGATTCGTTACCGCCATTCTGGTTTACTGGATAAAGAA
ACTTGGCAAACAGTATTTTTGCCGAAAATTAAAGCATTGAAGAACAAATGA

Upstream 100 bases:

>100_bases
ATTATAAACCACTGATTCGTTGGCTTTGGGCGGGCGGTATTTTAATGGCCGTTGGTGCACTTTTTAGCGTCTTCGGATTA
CGCAGAAAACAGGAAAAATA

Downstream 100 bases:

>100_bases
AAAGCATATTAGATATTTTTACTCGCGGTTTTATTCAGGTTCAAAAAACAGTCTTTTTTGCAACCGCACTTTTATTCGCA
TTTTCCTTATTCGCCCAAGC

Product: thiol-disulfide interchange protein

Products: NA

Alternate protein names: Cytochrome c biogenesis protein NrfX [H]

Number of amino acids: Translated: 176; Mature: 176

Protein sequence:

>176_residues
MNKKLIFFTPLFVLLGVCILLIAGLNQDPKKIASALIDKPVPEFYQANLHEPSQIVSPKEFPKQPFLLNVWGSWCGYCKE
EHPLLIEIAKTLPIVGVDYRDNPQNGIEMLKRMGNPFVLTIDDSHGKLGLKLGVDGAPETYLVDENGVIRYRHSGLLDKE
TWQTVFLPKIKALKNK

Sequences:

>Translated_176_residues
MNKKLIFFTPLFVLLGVCILLIAGLNQDPKKIASALIDKPVPEFYQANLHEPSQIVSPKEFPKQPFLLNVWGSWCGYCKE
EHPLLIEIAKTLPIVGVDYRDNPQNGIEMLKRMGNPFVLTIDDSHGKLGLKLGVDGAPETYLVDENGVIRYRHSGLLDKE
TWQTVFLPKIKALKNK
>Mature_176_residues
MNKKLIFFTPLFVLLGVCILLIAGLNQDPKKIASALIDKPVPEFYQANLHEPSQIVSPKEFPKQPFLLNVWGSWCGYCKE
EHPLLIEIAKTLPIVGVDYRDNPQNGIEMLKRMGNPFVLTIDDSHGKLGLKLGVDGAPETYLVDENGVIRYRHSGLLDKE
TWQTVFLPKIKALKNK

Specific function: Could be involved in disulfide bond formation. Could catalyzes a late, reductive step in the assembly of periplasmic NrfA c-type cytochrome, probably the reduction of disulfide bonds of the apocytochrome c to allow covalent linkage with the heme. Possible

COG id: COG0526

COG function: function code OC; Thiol-disulfide isomerase and thioredoxins

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein; Periplasmic side (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1788523, Length=173, Percent_Identity=41.0404624277457, Blast_Score=140, Evalue=4e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004799
- InterPro:   IPR013740
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR012335 [H]

Pfam domain/function: PF08534 Redoxin [H]

EC number: NA

Molecular weight: Translated: 19853; Mature: 19853

Theoretical pI: Translated: 8.46; Mature: 8.46

Prosite motif: PS00194 THIOREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKKLIFFTPLFVLLGVCILLIAGLNQDPKKIASALIDKPVPEFYQANLHEPSQIVSPKE
CCCCEEEHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHHCCCCCCHHHCCCHH
FPKQPFLLNVWGSWCGYCKEEHPLLIEIAKTLPIVGVDYRDNPQNGIEMLKRMGNPFVLT
CCCCCEEEEECHHHHCCCCCCCCEEEEEHHHCCEEECCCCCCCHHHHHHHHHCCCCEEEE
IDDSHGKLGLKLGVDGAPETYLVDENGVIRYRHSGLLDKETWQTVFLPKIKALKNK
EECCCCEEEEEECCCCCCCEEEECCCCEEEEECCCCCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNKKLIFFTPLFVLLGVCILLIAGLNQDPKKIASALIDKPVPEFYQANLHEPSQIVSPKE
CCCCEEEHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHHCCCCCCHHHCCCHH
FPKQPFLLNVWGSWCGYCKEEHPLLIEIAKTLPIVGVDYRDNPQNGIEMLKRMGNPFVLT
CCCCCEEEEECHHHHCCCCCCCCEEEEEHHHCCEEECCCCCCCHHHHHHHHHCCCCEEEE
IDDSHGKLGLKLGVDGAPETYLVDENGVIRYRHSGLLDKETWQTVFLPKIKALKNK
EECCCCEEEEEECCCCCCCEEEECCCCEEEEECCCCCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]