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The map label for this gene is dmsA [H]

Identifier: 148826334

GI number: 148826334

Start: 1354268

End: 1356562

Strand: Direct

Name: dmsA [H]

Synonym: CGSHiEE_06835

Alternate gene names: 148826334

Gene position: 1354268-1356562 (Clockwise)

Preceding gene: 148826330

Following gene: 148826335

Centisome position: 74.7

GC content: 38.47

Gene sequence:

>2295_bases
ATGAGTAACTTTAATCAAATAAGTCGCCGAGATTTTGTCAAGGCGTCATCTGCGGGAGCTGCACTGGCAGTTTCAAATCT
TACTTTACCTTTCAATGTAATGGCTAAAGAGACACAACGCCTCAATGAAAATAATCAAGAACGTATTGTTTGGAGTGCTT
GTACAGTAAACTGTGGTAGCCGTTGTCCATTACGAATGCACGTAAAAGATAACCGAATCACTTATGTGGAAACCGATAAT
ACGGGGACAGAAACATATAATCTTGATCATCAGGTTCGTGCTTGTCTACGTGGACGTTCTATGCGTCGTCGAGTATATAA
CCCAGACCGTTTAAAATATCCAATGAAACGTATAGGTAAACGCGGAGAAGGCAAATTCAAACGAATCAGTTGGGATGAGG
CTTTAACTGAAATTGCAGACGCATTGAAACGCAATATCAAAAAATATGGCAATGAATCAATTTATTTAAACTATGGTACG
GGAACACTCGGTGGCACAATGGCTAAATCTTGGCCACCTGCATCCACTATGATCGCTCGTTTTATGAATTGTATTGGTGG
ATATTTAAACCATTATGGTGATTACAGCACCGCACAAATTGCTGTCGGTTTAGATTATACCTATGGTGGTGGTTGGGCAT
TGGGAAATGGAATGGCTGACATTGAAAACACCAAATTAATAGTGTTATTCGGTAATAATCCTGCAGAAACTCGTATGAGT
GGAGGTGGTTTAACTTATTGTATTGAACAAGCCAAAGCTCGTTCCAATGCCAAAATGATTATTATCGATCCTCGTTATAA
TGATACTGGTGCAGGGCGTGAAGATGAGTGGATCCCAATTCGTCCAGGCACTGATGCAGCCCTCGTTTCTGCCCTTGCTT
ATGTAATGATTCAAGAAAATCTCGTGGATCAACCTTTCTTAGATAAATATTGTGTTGGTTATGATGAAAAAACATTACCT
GCGGATGCCCCTAAAAATGGTCATTATAAAGCCTATATTTTAGGTTATGGTAATGATGGTATCGCTAAAACCCCAGAATG
GGCGGCTAAAATCACGGGTATTCCAGCGGAGAGAATTATTAAACTCGCACGTGAAATTGGTAGTATAAAACCTGCCTTTA
TTTCCCAAGGTTGGGGGCCTCAACGTCGTAGTAATGGAGAATTAATCTCTCGTGCCATTGCAATGTTACCAATCTTAACG
GGTAATGTTGGAATTCACGGCGGTAACACTGGTGCACGTGAAAGTGCGTATAGCATTCCATTTGTGCGGATGCCAACGCT
GAAAAATCCTGTGAAAGCAAGCATTCCAATGTTTTTATGGACAGATGCAATTATTCGTGGCACAGAAATGACCGCACTTA
CAGATGGTATTCGTGGTGTTGATAAATTATCGTCCCCAATTAAAGTAATTTGGAATTACGCAAGTAACTGTTTGATTAAT
CAACACGCACAAATCAATCGTACTCACGATATTTTACAAGATGATACCCAATGTGAAATGATCATTACTATTGATAATCA
TATGACATCTACTGCCAAATACAGTGATATTTTATTACCAGATTGTACAACTTCAGAACAAATGGATTTCGCTTTAGATG
CCTTTGTATCCAATATGGCATATGTCATTTTTGCAGATCAAGTGATCAAACCATCTTTTGAATGTAGACCTATTTACGAT
ATGTTGAGTGATTTAGCTGAGAAAATGGGCGTAAAGGAAAAATTTACTGAAGGACGAACACAAGAAGAGTGGTTACGCCA
TATTTATAAGCAATCTCGAGAAAAATTACCTGAATTACCCACTTTTGAAGAATTTAGACAACAAGGTATTTTTAAAAAAG
TTGATCCTAATGGCTTTAAAGTTGCATACAAAGATTTCCGTGATAATCCAGAAGCCCATCCACTTAAAACGCCATCTGGC
AAAATTGAAATTTATTCTTCTCGTCTAGCTGAAATAGCAAAAACTTGGAAATTAGCAGAAGATGACGTAATTCATCCCTT
ACCTATTCACGCCCAAAGTTTTGAGCATTACGGTGATCCATTAATGGAAAAATATCCGTTACAACTAAGTGGTTTTCACT
ATAAAGCGAGAACCCATTCAACTTATGGCAATGTGGATGTATTAAAAGCAGCTAATCCACAAGAAGTTTGGATGAATCCT
ATTGATGCAAAACCTCGTAATATTAAAAATGGCGATATGATTCGTATCTTTAATGATCGAGGCGAAGTACATATTAATGT
AAAAATTACACCCCGTATTATTCCGGGGGTTGTGGCATTAAGCGAGGGGGCTTGA

Upstream 100 bases:

>100_bases
ATTAATGATTAATTGATTTGGCTCAAGTAAAACTTCTATACAAAGATTATAATTAACTCGTTTTAGTTATTTTTCAATCT
GACTGTGGGGGAACGATATA

Downstream 100 bases:

>100_bases
TATGCACCAGATAAAGATCGTATCGATCATTCAGGTTGCATTAATGTACTTACGACACAACGCCCATCACCGCTTGCGAA
AGGTAATCCGCAACATTCTA

Product: anaerobic dimethyl sulfoxide reductase chain A

Products: Reduced form of N-Oxide compounds [C]

Alternate protein names: DMSO reductase [H]

Number of amino acids: Translated: 764; Mature: 763

Protein sequence:

>764_residues
MSNFNQISRRDFVKASSAGAALAVSNLTLPFNVMAKETQRLNENNQERIVWSACTVNCGSRCPLRMHVKDNRITYVETDN
TGTETYNLDHQVRACLRGRSMRRRVYNPDRLKYPMKRIGKRGEGKFKRISWDEALTEIADALKRNIKKYGNESIYLNYGT
GTLGGTMAKSWPPASTMIARFMNCIGGYLNHYGDYSTAQIAVGLDYTYGGGWALGNGMADIENTKLIVLFGNNPAETRMS
GGGLTYCIEQAKARSNAKMIIIDPRYNDTGAGREDEWIPIRPGTDAALVSALAYVMIQENLVDQPFLDKYCVGYDEKTLP
ADAPKNGHYKAYILGYGNDGIAKTPEWAAKITGIPAERIIKLAREIGSIKPAFISQGWGPQRRSNGELISRAIAMLPILT
GNVGIHGGNTGARESAYSIPFVRMPTLKNPVKASIPMFLWTDAIIRGTEMTALTDGIRGVDKLSSPIKVIWNYASNCLIN
QHAQINRTHDILQDDTQCEMIITIDNHMTSTAKYSDILLPDCTTSEQMDFALDAFVSNMAYVIFADQVIKPSFECRPIYD
MLSDLAEKMGVKEKFTEGRTQEEWLRHIYKQSREKLPELPTFEEFRQQGIFKKVDPNGFKVAYKDFRDNPEAHPLKTPSG
KIEIYSSRLAEIAKTWKLAEDDVIHPLPIHAQSFEHYGDPLMEKYPLQLSGFHYKARTHSTYGNVDVLKAANPQEVWMNP
IDAKPRNIKNGDMIRIFNDRGEVHINVKITPRIIPGVVALSEGA

Sequences:

>Translated_764_residues
MSNFNQISRRDFVKASSAGAALAVSNLTLPFNVMAKETQRLNENNQERIVWSACTVNCGSRCPLRMHVKDNRITYVETDN
TGTETYNLDHQVRACLRGRSMRRRVYNPDRLKYPMKRIGKRGEGKFKRISWDEALTEIADALKRNIKKYGNESIYLNYGT
GTLGGTMAKSWPPASTMIARFMNCIGGYLNHYGDYSTAQIAVGLDYTYGGGWALGNGMADIENTKLIVLFGNNPAETRMS
GGGLTYCIEQAKARSNAKMIIIDPRYNDTGAGREDEWIPIRPGTDAALVSALAYVMIQENLVDQPFLDKYCVGYDEKTLP
ADAPKNGHYKAYILGYGNDGIAKTPEWAAKITGIPAERIIKLAREIGSIKPAFISQGWGPQRRSNGELISRAIAMLPILT
GNVGIHGGNTGARESAYSIPFVRMPTLKNPVKASIPMFLWTDAIIRGTEMTALTDGIRGVDKLSSPIKVIWNYASNCLIN
QHAQINRTHDILQDDTQCEMIITIDNHMTSTAKYSDILLPDCTTSEQMDFALDAFVSNMAYVIFADQVIKPSFECRPIYD
MLSDLAEKMGVKEKFTEGRTQEEWLRHIYKQSREKLPELPTFEEFRQQGIFKKVDPNGFKVAYKDFRDNPEAHPLKTPSG
KIEIYSSRLAEIAKTWKLAEDDVIHPLPIHAQSFEHYGDPLMEKYPLQLSGFHYKARTHSTYGNVDVLKAANPQEVWMNP
IDAKPRNIKNGDMIRIFNDRGEVHINVKITPRIIPGVVALSEGA
>Mature_763_residues
SNFNQISRRDFVKASSAGAALAVSNLTLPFNVMAKETQRLNENNQERIVWSACTVNCGSRCPLRMHVKDNRITYVETDNT
GTETYNLDHQVRACLRGRSMRRRVYNPDRLKYPMKRIGKRGEGKFKRISWDEALTEIADALKRNIKKYGNESIYLNYGTG
TLGGTMAKSWPPASTMIARFMNCIGGYLNHYGDYSTAQIAVGLDYTYGGGWALGNGMADIENTKLIVLFGNNPAETRMSG
GGLTYCIEQAKARSNAKMIIIDPRYNDTGAGREDEWIPIRPGTDAALVSALAYVMIQENLVDQPFLDKYCVGYDEKTLPA
DAPKNGHYKAYILGYGNDGIAKTPEWAAKITGIPAERIIKLAREIGSIKPAFISQGWGPQRRSNGELISRAIAMLPILTG
NVGIHGGNTGARESAYSIPFVRMPTLKNPVKASIPMFLWTDAIIRGTEMTALTDGIRGVDKLSSPIKVIWNYASNCLINQ
HAQINRTHDILQDDTQCEMIITIDNHMTSTAKYSDILLPDCTTSEQMDFALDAFVSNMAYVIFADQVIKPSFECRPIYDM
LSDLAEKMGVKEKFTEGRTQEEWLRHIYKQSREKLPELPTFEEFRQQGIFKKVDPNGFKVAYKDFRDNPEAHPLKTPSGK
IEIYSSRLAEIAKTWKLAEDDVIHPLPIHAQSFEHYGDPLMEKYPLQLSGFHYKARTHSTYGNVDVLKAANPQEVWMNPI
DAKPRNIKNGDMIRIFNDRGEVHINVKITPRIIPGVVALSEGA

Specific function: Terminal reductase during anaerobic growth on various sulfoxide and N-oxide compounds [H]

COG id: COG0243

COG function: function code C; Anaerobic dehydrogenases, typically selenocysteine-containing

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI87081797, Length=761, Percent_Identity=73.1931668856767, Blast_Score=1177, Evalue=0.0,
Organism=Escherichia coli, GI1787870, Length=761, Percent_Identity=63.9947437582129, Blast_Score=1045, Evalue=0.0,
Organism=Escherichia coli, GI171474008, Length=762, Percent_Identity=61.1548556430446, Blast_Score=981, Evalue=0.0,
Organism=Escherichia coli, GI1787231, Length=761, Percent_Identity=30.6176084099869, Blast_Score=280, Evalue=2e-76,
Organism=Escherichia coli, GI145693196, Length=713, Percent_Identity=30.9957924263675, Blast_Score=275, Evalue=9e-75,
Organism=Escherichia coli, GI87081994, Length=818, Percent_Identity=28.6063569682152, Blast_Score=258, Evalue=1e-69,
Organism=Escherichia coli, GI3868721, Length=755, Percent_Identity=25.1655629139073, Blast_Score=139, Evalue=6e-34,
Organism=Escherichia coli, GI3868720, Length=469, Percent_Identity=26.0127931769723, Blast_Score=105, Evalue=1e-23,
Organism=Escherichia coli, GI3868719, Length=465, Percent_Identity=24.9462365591398, Blast_Score=93, Evalue=5e-20,
Organism=Escherichia coli, GI1788534, Length=820, Percent_Identity=23.780487804878, Blast_Score=92, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011888
- InterPro:   IPR009010
- InterPro:   IPR006657
- InterPro:   IPR006656
- InterPro:   IPR006963
- InterPro:   IPR006655
- InterPro:   IPR006311 [H]

Pfam domain/function: PF04879 Molybdop_Fe4S4; PF00384 Molybdopterin; PF01568 Molydop_binding [H]

EC number: 1.8.99.- [C]

Molecular weight: Translated: 85687; Mature: 85556

Theoretical pI: Translated: 8.62; Mature: 8.62

Prosite motif: PS00551 MOLYBDOPTERIN_PROK_1 ; PS00490 MOLYBDOPTERIN_PROK_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNFNQISRRDFVKASSAGAALAVSNLTLPFNVMAKETQRLNENNQERIVWSACTVNCGS
CCCHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHCCCCCCEEEEEEEEECCCC
RCPLRMHVKDNRITYVETDNTGTETYNLDHQVRACLRGRSMRRRVYNPDRLKYPMKRIGK
CCCEEEEEECCEEEEEEECCCCCEEECCHHHHHHHHHCHHHHHHCCCCHHHHCHHHHCCC
RGEGKFKRISWDEALTEIADALKRNIKKYGNESIYLNYGTGTLGGTMAKSWPPASTMIAR
CCCCCEEEECHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCHHHHHHH
FMNCIGGYLNHYGDYSTAQIAVGLDYTYGGGWALGNGMADIENTKLIVLFGNNPAETRMS
HHHHHHHHHHHCCCCCCEEEEEEEEEECCCCEEECCCCCCCCCCEEEEEECCCCHHCEEC
GGGLTYCIEQAKARSNAKMIIIDPRYNDTGAGREDEWIPIRPGTDAALVSALAYVMIQEN
CCCHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHH
LVDQPFLDKYCVGYDEKTLPADAPKNGHYKAYILGYGNDGIAKTPEWAAKITGIPAERII
CCCCCCHHHHHCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCHHHHCCCCCHHHHH
KLAREIGSIKPAFISQGWGPQRRSNGELISRAIAMLPILTGNVGIHGGNTGARESAYSIP
HHHHHHCCCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHEECCEEEECCCCCCCCCCCCCC
FVRMPTLKNPVKASIPMFLWTDAIIRGTEMTALTDGIRGVDKLSSPIKVIWNYASNCLIN
EEECCCCCCCCHHCCCHHEEHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHCCEEC
QHAQINRTHDILQDDTQCEMIITIDNHMTSTAKYSDILLPDCTTSEQMDFALDAFVSNMA
CCCCCCCHHHHHCCCCCEEEEEEECCCCCCCCCCCCEECCCCCCCHHHHHHHHHHHHCCE
YVIFADQVIKPSFECRPIYDMLSDLAEKMGVKEKFTEGRTQEEWLRHIYKQSREKLPELP
EEEEEHHHHCCCCCCCCHHHHHHHHHHHCCCHHHHHCCCCHHHHHHHHHHHHHHHCCCCC
TFEEFRQQGIFKKVDPNGFKVAYKDFRDNPEAHPLKTPSGKIEIYSSRLAEIAKTWKLAE
CHHHHHHCCCCEECCCCCEEEEEEHHCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHCCCC
DDVIHPLPIHAQSFEHYGDPLMEKYPLQLSGFHYKARTHSTYGNVDVLKAANPQEVWMNP
CCCCCCCCCCHHHHHHHCCHHHHHCCCEECCEEEEEECCCCCCCEEEEECCCCHHHCCCC
IDAKPRNIKNGDMIRIFNDRGEVHINVKITPRIIPGVVALSEGA
CCCCCCCCCCCCEEEEECCCCEEEEEEEECCEECCCEEEECCCC
>Mature Secondary Structure 
SNFNQISRRDFVKASSAGAALAVSNLTLPFNVMAKETQRLNENNQERIVWSACTVNCGS
CCHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHCCCCCCEEEEEEEEECCCC
RCPLRMHVKDNRITYVETDNTGTETYNLDHQVRACLRGRSMRRRVYNPDRLKYPMKRIGK
CCCEEEEEECCEEEEEEECCCCCEEECCHHHHHHHHHCHHHHHHCCCCHHHHCHHHHCCC
RGEGKFKRISWDEALTEIADALKRNIKKYGNESIYLNYGTGTLGGTMAKSWPPASTMIAR
CCCCCEEEECHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCHHHHHHH
FMNCIGGYLNHYGDYSTAQIAVGLDYTYGGGWALGNGMADIENTKLIVLFGNNPAETRMS
HHHHHHHHHHHCCCCCCEEEEEEEEEECCCCEEECCCCCCCCCCEEEEEECCCCHHCEEC
GGGLTYCIEQAKARSNAKMIIIDPRYNDTGAGREDEWIPIRPGTDAALVSALAYVMIQEN
CCCHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHH
LVDQPFLDKYCVGYDEKTLPADAPKNGHYKAYILGYGNDGIAKTPEWAAKITGIPAERII
CCCCCCHHHHHCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCHHHHCCCCCHHHHH
KLAREIGSIKPAFISQGWGPQRRSNGELISRAIAMLPILTGNVGIHGGNTGARESAYSIP
HHHHHHCCCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHEECCEEEECCCCCCCCCCCCCC
FVRMPTLKNPVKASIPMFLWTDAIIRGTEMTALTDGIRGVDKLSSPIKVIWNYASNCLIN
EEECCCCCCCCHHCCCHHEEHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHCCEEC
QHAQINRTHDILQDDTQCEMIITIDNHMTSTAKYSDILLPDCTTSEQMDFALDAFVSNMA
CCCCCCCHHHHHCCCCCEEEEEEECCCCCCCCCCCCEECCCCCCCHHHHHHHHHHHHCCE
YVIFADQVIKPSFECRPIYDMLSDLAEKMGVKEKFTEGRTQEEWLRHIYKQSREKLPELP
EEEEEHHHHCCCCCCCCHHHHHHHHHHHCCCHHHHHCCCCHHHHHHHHHHHHHHHCCCCC
TFEEFRQQGIFKKVDPNGFKVAYKDFRDNPEAHPLKTPSGKIEIYSSRLAEIAKTWKLAE
CHHHHHHCCCCEECCCCCEEEEEEHHCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHCCCC
DDVIHPLPIHAQSFEHYGDPLMEKYPLQLSGFHYKARTHSTYGNVDVLKAANPQEVWMNP
CCCCCCCCCCHHHHHHHCCHHHHHCCCEECCEEEEEECCCCCCCEEEEECCCCHHHCCCC
IDAKPRNIKNGDMIRIFNDRGEVHINVKITPRIIPGVVALSEGA
CCCCCCCCCCCCEEEEECCCCEEEEEEEECCEECCCEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: May Bind 4Fe-4S Cluster. [C]

Metal ions: Fe; Mo [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: N-Oxide; Sulfoxide Compounds Including Trimethylamine N-Oxide. [C]

Specific reaction: Reduces Various N-Oxide And Sulfoxide Compounds Including Trimethylamine N-Oxide. [C]

General reaction: Oxidoreductases [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800; 8635740 [H]