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The map label for this gene is pnuC [H]

Identifier: 148826308

GI number: 148826308

Start: 1321503

End: 1322183

Strand: Direct

Name: pnuC [H]

Synonym: CGSHiEE_06685

Alternate gene names: 148826308

Gene position: 1321503-1322183 (Clockwise)

Preceding gene: 148826307

Following gene: 148826310

Centisome position: 72.89

GC content: 35.39

Gene sequence:

>681_bases
ATGACTTTGGCAGCGCGTTTAAAACGAGAATTTGTTTCTGGTTGGAAACCTTTTGAGGTGGTTTGGCTTGCGCTTTTTAT
CATTGCGCAAATTTGGGCTTATGTACAAACACCTGATTCTTGGTTAGCAATGATTTCTGGTATTTCTGGTATTTTGTGTG
TGGTATTGGTAAGTAAAGGTAAAATTAGTAATTATTTCTTTGGATTGATTTTTGCCTATACTTATTTTTATGTTGCTTGG
GGATCGAATTTCTTAGGCGAAATGAATACTGTACTTTACGTATATTTGCCCTCTCAATTTATTGGTTACTTTATGTGGAA
AGCCAATATGCAAAATAGCGATGGTGGAGAAAGCGTGATTGCAAAAGCGTTAACTGTTAAAGGATGGATGACATTAATTG
TTATGACTACGGTTGGTACTTTGCTTTTTGTTCAAGCATTACAAGCGGCTGGTGGTAGTTCAACAGGTTTAGATGGTCTA
ACTACAATTATTACGGTTGCGGCACAGATTTTAATGATTTTGCGTTATCGTGAACAATGGTTGTTATGGATTGGATTAAA
TATTCTTTCTATTTTCTTATGGGCAGAGACACCTGCAATATACTTAATGTATTCAGCCTACTTACTTAACTCGTTGTATG
GTTATTATAACTGGACGAAATTAGTTAAGCGTACTAACTAA

Upstream 100 bases:

>100_bases
CACAACTTTAGAATTAAATACTTCTACACCTTTACATTACCAATTCACTATGCAAGAATAAGAATGCTCACGTTAAAATT
TAAGTCAATAGGAGTAAATA

Downstream 100 bases:

>100_bases
ATATAAAAACAGTAAATAGCTTATAAAAAATCCCGTTAATGATAAATTTAACGGGGATTTTTTACTTCAAAAACATCAAG
TTATATCATAACCAAATAAA

Product: UDP-N-acetylglucosamine 1-carboxyvinyltransferase

Products: nicotinamide nucleotide [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 226; Mature: 225

Protein sequence:

>226_residues
MTLAARLKREFVSGWKPFEVVWLALFIIAQIWAYVQTPDSWLAMISGISGILCVVLVSKGKISNYFFGLIFAYTYFYVAW
GSNFLGEMNTVLYVYLPSQFIGYFMWKANMQNSDGGESVIAKALTVKGWMTLIVMTTVGTLLFVQALQAAGGSSTGLDGL
TTIITVAAQILMILRYREQWLLWIGLNILSIFLWAETPAIYLMYSAYLLNSLYGYYNWTKLVKRTN

Sequences:

>Translated_226_residues
MTLAARLKREFVSGWKPFEVVWLALFIIAQIWAYVQTPDSWLAMISGISGILCVVLVSKGKISNYFFGLIFAYTYFYVAW
GSNFLGEMNTVLYVYLPSQFIGYFMWKANMQNSDGGESVIAKALTVKGWMTLIVMTTVGTLLFVQALQAAGGSSTGLDGL
TTIITVAAQILMILRYREQWLLWIGLNILSIFLWAETPAIYLMYSAYLLNSLYGYYNWTKLVKRTN
>Mature_225_residues
TLAARLKREFVSGWKPFEVVWLALFIIAQIWAYVQTPDSWLAMISGISGILCVVLVSKGKISNYFFGLIFAYTYFYVAWG
SNFLGEMNTVLYVYLPSQFIGYFMWKANMQNSDGGESVIAKALTVKGWMTLIVMTTVGTLLFVQALQAAGGSSTGLDGLT
TIITVAAQILMILRYREQWLLWIGLNILSIFLWAETPAIYLMYSAYLLNSLYGYYNWTKLVKRTN

Specific function: Required for nicotinamide riboside transport across the inner membrane [H]

COG id: COG3201

COG function: function code H; Nicotinamide mononucleotide transporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006419 [H]

Pfam domain/function: PF04973 NMN_transporter [H]

EC number: NA

Molecular weight: Translated: 25591; Mature: 25459

Theoretical pI: Translated: 9.46; Mature: 9.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLAARLKREFVSGWKPFEVVWLALFIIAQIWAYVQTPDSWLAMISGISGILCVVLVSKG
CCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCC
KISNYFFGLIFAYTYFYVAWGSNFLGEMNTVLYVYLPSQFIGYFMWKANMQNSDGGESVI
CHHHHHHHHHHHHHHHHHHHCCHHHHCCCCEEEEEEHHHHHHHHHHCCCCCCCCCHHHHH
AKALTVKGWMTLIVMTTVGTLLFVQALQAAGGSSTGLDGLTTIITVAAQILMILRYREQW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LLWIGLNILSIFLWAETPAIYLMYSAYLLNSLYGYYNWTKLVKRTN
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TLAARLKREFVSGWKPFEVVWLALFIIAQIWAYVQTPDSWLAMISGISGILCVVLVSKG
CHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCC
KISNYFFGLIFAYTYFYVAWGSNFLGEMNTVLYVYLPSQFIGYFMWKANMQNSDGGESVI
CHHHHHHHHHHHHHHHHHHHCCHHHHCCCCEEEEEEHHHHHHHHHHCCCCCCCCCHHHHH
AKALTVKGWMTLIVMTTVGTLLFVQALQAAGGSSTGLDGLTTIITVAAQILMILRYREQW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LLWIGLNILSIFLWAETPAIYLMYSAYLLNSLYGYYNWTKLVKRTN
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: nicotinamide nucleotide [Periplasm] [C]

Specific reaction: nicotinamide nucleotide [Periplasm] = nicotinamide nucleotide [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12446641; 7542800 [H]