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The map label for this gene is comM [H]

Identifier: 148826268

GI number: 148826268

Start: 1282153

End: 1283682

Strand: Direct

Name: comM [H]

Synonym: CGSHiEE_06465

Alternate gene names: 148826268

Gene position: 1282153-1283682 (Clockwise)

Preceding gene: 148826267

Following gene: 148826270

Centisome position: 70.72

GC content: 43.33

Gene sequence:

>1530_bases
ATGTCCCTTGCTATTGTTTACAGCCGTGCTTCTATGGGTGTGCAAGCACCGCTAGTCACCATTGAGGTGCATTTAAGCAA
CGGAAAACCAGGATTTACACTTGTTGGTTTGCCAGAAAAAACCGTGAAAGAGGCACAAGATCGGGTGCGTAGTGCGTTGA
TGAATGCACAATTTAAATACCCAGCCAAGCGTATCACTGTAAATCTCGCCCCTGCGGATTTACCGAAAGAAGGCGGAAGA
TTTGATTTGCCTATTGCTATCGGGATTTTAGCTGCATCAGATCAGCTTGATGCAAGCCGTTTAAAGCAATTTGAATTTGT
GGCAGAGCTTGCGCTGACGGGCCAATTGCGTGGCGTACATGGTGTGATTCCCGCTATTCTTGCAGCGCAAAAGTCAAAGC
GAGAGTTAATTATCGCGAAACAAAATGCTAATGAAGCCTCGCTCGTGTCTGATCAAAATACTTATTTTGCTCAAACGCTT
TTAGATGTAGTGCAATTTCTCAATGGTCAGGAAAAATTACCCCTCGCCACTGAAATTGTGAAAGAAAGTGCGGTAAATTT
TTCAGGTAAAAATACGTTAGATTTAACGGATATTATCGGACAACAGCACGCTAAACGAGCATTGACCATTGCCGCAGCGG
GGCAGCATAATTTGCTCTTTCTTGGCCCACCGGGTACAGGGAAAACCATGTTAGCCAGCCGTTTGACAGGGCTTTTACCT
GAAATGACAGATCTAGAAGCGATAGAAACAGCATCTGTAACGAGTTTAGTTCAAAACGAGTTAAATTTTCATAATTGGAA
GCAACGTCCTTTTCGCGCCCCACATCATAGTGCATCAATGCCGGCTTTAGTTGGTGGCGGAACGATCCCTAAACCTGGCG
AAATATCCTTAGCAACAAATGGGGTGCTTTTTCTTGATGAACTTCCAGAATTTGAGCGAAAAGTGTTAGATGCACTACGC
CAGCCTTTGGAAAGTGGTGAGATTATTATTTCTCGTGCCAATGCAAAAATTCAATTCCCAGCTCGTTTTCAATTAGTGGC
AGCGATGAATCCAAGCCCTACAGGCCATTATACTGGGACACATAACCGCACTTCACCACAGCAAATTATGCGTTATTTGA
ATCGACTTTCAGGGCCATTTTTAGATCGTTTTGATTTATCTATTGAAGTGCCTTTACTGCCACAAGGTAGCTTGCAAAAT
ACGGGCGATCGTGGCGAAACCAGCGTGCAAGTTCGTGAAAAAGTGTTAAAAGTACGTGAGATTCAAATGGAAAGAGCGGG
GAAAATCAACGCTTATTTGAACAGTAAAGAGATTGAGCGTGATTGCAAGTTAAATGATAAAGATGCCTTTTTCCTTGAAA
AAGCACTGAATAAACTTGGGCTTTCTGTACGGGCTTATCATCGTATTTTGAAAGTTTCTCGAACCATTGCCGATCTACAA
GGAGAACAACAAATTTCTCAACCGCACTTGGCGGAGGCCTTGGGCTATCGAGCAATGGATCGTTTGCTGCAGAAATTGTC
GAATATGTAA

Upstream 100 bases:

>100_bases
ATCTAGATCGCAAAAAAAGCACGGAATGAAATCATTCATTACGTGTCTTTTTTTATAGTGCAAAAACTATCTTCATTTTT
ACCGCACTTTAAGGATTATC

Downstream 100 bases:

>100_bases
AAACGCGTGGAAAGAATACCACGCGTGAAAGGATTAGTAAGTGCTTTGAGTGTCTTGCGTACCGCTAATAATTGCAATGC
CAGCGCTTGCACCAATGCGA

Product: GTPase EngB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 509; Mature: 508

Protein sequence:

>509_residues
MSLAIVYSRASMGVQAPLVTIEVHLSNGKPGFTLVGLPEKTVKEAQDRVRSALMNAQFKYPAKRITVNLAPADLPKEGGR
FDLPIAIGILAASDQLDASRLKQFEFVAELALTGQLRGVHGVIPAILAAQKSKRELIIAKQNANEASLVSDQNTYFAQTL
LDVVQFLNGQEKLPLATEIVKESAVNFSGKNTLDLTDIIGQQHAKRALTIAAAGQHNLLFLGPPGTGKTMLASRLTGLLP
EMTDLEAIETASVTSLVQNELNFHNWKQRPFRAPHHSASMPALVGGGTIPKPGEISLATNGVLFLDELPEFERKVLDALR
QPLESGEIIISRANAKIQFPARFQLVAAMNPSPTGHYTGTHNRTSPQQIMRYLNRLSGPFLDRFDLSIEVPLLPQGSLQN
TGDRGETSVQVREKVLKVREIQMERAGKINAYLNSKEIERDCKLNDKDAFFLEKALNKLGLSVRAYHRILKVSRTIADLQ
GEQQISQPHLAEALGYRAMDRLLQKLSNM

Sequences:

>Translated_509_residues
MSLAIVYSRASMGVQAPLVTIEVHLSNGKPGFTLVGLPEKTVKEAQDRVRSALMNAQFKYPAKRITVNLAPADLPKEGGR
FDLPIAIGILAASDQLDASRLKQFEFVAELALTGQLRGVHGVIPAILAAQKSKRELIIAKQNANEASLVSDQNTYFAQTL
LDVVQFLNGQEKLPLATEIVKESAVNFSGKNTLDLTDIIGQQHAKRALTIAAAGQHNLLFLGPPGTGKTMLASRLTGLLP
EMTDLEAIETASVTSLVQNELNFHNWKQRPFRAPHHSASMPALVGGGTIPKPGEISLATNGVLFLDELPEFERKVLDALR
QPLESGEIIISRANAKIQFPARFQLVAAMNPSPTGHYTGTHNRTSPQQIMRYLNRLSGPFLDRFDLSIEVPLLPQGSLQN
TGDRGETSVQVREKVLKVREIQMERAGKINAYLNSKEIERDCKLNDKDAFFLEKALNKLGLSVRAYHRILKVSRTIADLQ
GEQQISQPHLAEALGYRAMDRLLQKLSNM
>Mature_508_residues
SLAIVYSRASMGVQAPLVTIEVHLSNGKPGFTLVGLPEKTVKEAQDRVRSALMNAQFKYPAKRITVNLAPADLPKEGGRF
DLPIAIGILAASDQLDASRLKQFEFVAELALTGQLRGVHGVIPAILAAQKSKRELIIAKQNANEASLVSDQNTYFAQTLL
DVVQFLNGQEKLPLATEIVKESAVNFSGKNTLDLTDIIGQQHAKRALTIAAAGQHNLLFLGPPGTGKTMLASRLTGLLPE
MTDLEAIETASVTSLVQNELNFHNWKQRPFRAPHHSASMPALVGGGTIPKPGEISLATNGVLFLDELPEFERKVLDALRQ
PLESGEIIISRANAKIQFPARFQLVAAMNPSPTGHYTGTHNRTSPQQIMRYLNRLSGPFLDRFDLSIEVPLLPQGSLQNT
GDRGETSVQVREKVLKVREIQMERAGKINAYLNSKEIERDCKLNDKDAFFLEKALNKLGLSVRAYHRILKVSRTIADLQG
EQQISQPHLAEALGYRAMDRLLQKLSNM

Specific function: Induced during competence development. Not needed for DNA uptake. May be involved in a recombination step [H]

COG id: COG0606

COG function: function code O; Predicted ATPase with chaperone activity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily [H]

Homologues:

Organism=Escherichia coli, GI145693202, Length=511, Percent_Identity=58.9041095890411, Blast_Score=617, Evalue=1e-178,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR001208
- InterPro:   IPR004482
- InterPro:   IPR000523
- InterPro:   IPR020568 [H]

Pfam domain/function: PF01078 Mg_chelatase [H]

EC number: NA

Molecular weight: Translated: 55919; Mature: 55788

Theoretical pI: Translated: 9.87; Mature: 9.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLAIVYSRASMGVQAPLVTIEVHLSNGKPGFTLVGLPEKTVKEAQDRVRSALMNAQFKY
CCEEEEEECCCCCCCCCEEEEEEEECCCCCCEEEEECCHHHHHHHHHHHHHHHHCCCCCC
PAKRITVNLAPADLPKEGGRFDLPIAIGILAASDQLDASRLKQFEFVAELALTGQLRGVH
CCEEEEEEECCCCCCCCCCCEECCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCHH
GVIPAILAAQKSKRELIIAKQNANEASLVSDQNTYFAQTLLDVVQFLNGQEKLPLATEIV
HHHHHHHHHCCCCCEEEEEECCCCCCCEECCCCHHHHHHHHHHHHHHCCCCCCCHHHHHH
KESAVNFSGKNTLDLTDIIGQQHAKRALTIAAAGQHNLLFLGPPGTGKTMLASRLTGLLP
HHHHCCCCCCCCCHHHHHHHHHHHHHEEEEEECCCCCEEEECCCCCCHHHHHHHHHHHCC
EMTDLEAIETASVTSLVQNELNFHNWKQRPFRAPHHSASMPALVGGGTIPKPGEISLATN
CCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCEEEEEC
GVLFLDELPEFERKVLDALRQPLESGEIIISRANAKIQFPARFQLVAAMNPSPTGHYTGT
CEEEECCCCHHHHHHHHHHHCCCCCCCEEEEECCCEEECCCEEEEEEECCCCCCCCCCCC
HNRTSPQQIMRYLNRLSGPFLDRFDLSIEVPLLPQGSLQNTGDRGETSVQVREKVLKVRE
CCCCCHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
IQMERAGKINAYLNSKEIERDCKLNDKDAFFLEKALNKLGLSVRAYHRILKVSRTIADLQ
HHHHHCCCEEEEECHHHHHHHCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCC
GEQQISQPHLAEALGYRAMDRLLQKLSNM
CHHHCCCCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SLAIVYSRASMGVQAPLVTIEVHLSNGKPGFTLVGLPEKTVKEAQDRVRSALMNAQFKY
CEEEEEECCCCCCCCCEEEEEEEECCCCCCEEEEECCHHHHHHHHHHHHHHHHCCCCCC
PAKRITVNLAPADLPKEGGRFDLPIAIGILAASDQLDASRLKQFEFVAELALTGQLRGVH
CCEEEEEEECCCCCCCCCCCEECCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCHH
GVIPAILAAQKSKRELIIAKQNANEASLVSDQNTYFAQTLLDVVQFLNGQEKLPLATEIV
HHHHHHHHHCCCCCEEEEEECCCCCCCEECCCCHHHHHHHHHHHHHHCCCCCCCHHHHHH
KESAVNFSGKNTLDLTDIIGQQHAKRALTIAAAGQHNLLFLGPPGTGKTMLASRLTGLLP
HHHHCCCCCCCCCHHHHHHHHHHHHHEEEEEECCCCCEEEECCCCCCHHHHHHHHHHHCC
EMTDLEAIETASVTSLVQNELNFHNWKQRPFRAPHHSASMPALVGGGTIPKPGEISLATN
CCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCEEEEEC
GVLFLDELPEFERKVLDALRQPLESGEIIISRANAKIQFPARFQLVAAMNPSPTGHYTGT
CEEEECCCCHHHHHHHHHHHCCCCCCCEEEEECCCEEECCCEEEEEEECCCCCCCCCCCC
HNRTSPQQIMRYLNRLSGPFLDRFDLSIEVPLLPQGSLQNTGDRGETSVQVREKVLKVRE
CCCCCHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
IQMERAGKINAYLNSKEIERDCKLNDKDAFFLEKALNKLGLSVRAYHRILKVSRTIADLQ
HHHHHCCCEEEEECHHHHHHHCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCC
GEQQISQPHLAEALGYRAMDRLLQKLSNM
CHHHCCCCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800; 9457884 [H]