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The map label for this gene is gmhA [H]

Identifier: 148826209

GI number: 148826209

Start: 1218979

End: 1219563

Strand: Direct

Name: gmhA [H]

Synonym: CGSHiEE_06140

Alternate gene names: 148826209

Gene position: 1218979-1219563 (Clockwise)

Preceding gene: 148826207

Following gene: 148826210

Centisome position: 67.23

GC content: 36.58

Gene sequence:

>585_bases
ATGTATTTAGATCAAATCAAAGCAGAACTTGTGGAAGCACAAGATTTGTTAAACAAATTTATTTCTGACGAAAATAACAT
TAAATTAATTCAAGAAGCGGCATTATTAATTTCGAATAGCTTCAAACAAGGAGGCAAAGTGCTTTCTTGTGGTAATGGCG
GTTCGCACTGTGATGCGATGCATTTTGCAGAAGAATTAACGGGTCGTTATCGTGAAAATCGCCCAGGTTATCCTGCTATT
GCGATTTCAGATGCAAGCCATTTAAGCTGTGTAAGTAATGATTTTGGTTATGAATATGTCTTTTCTCGCTATGTTGAAGC
GGTGGGGCAAAAAGGCGATGTATTATTCGGTTTATCAACCTCTGGTAATTCAAAAAATATTTTAAACGCCATTGAAGCGG
CAAAAACAAAAGGCATGAAAGTGATTGCGATGACAGGCAAAGATGGCGGAAAAATGGCAGGATTAGCGGATGTTGAAATT
CGCATACCCCATTTCCGTTATGCAGATCGTATTCAAGAAATCCATATCAAAGTTATTCATATTTTAATGATGTTAATTGA
GTTTGAAATGGCAAAACAAGCCTAA

Upstream 100 bases:

>100_bases
TCATTTCATCGAAAAAAGATGAATTTTTATTTAGGCTAGCGAAGAATCTTCATCTGCTATACAATGCCATTGCGATTTTA
TTCCCAACAAGGAGCAATCA

Downstream 100 bases:

>100_bases
AGTGCGGTTGATTTCAAGCGAGTTTTTTAAATCCCAAAATTTTTTGGGATTTTTATTAATAGCACTTGCATAATTATGCA
TAAAAATGTAATATTTTTTC

Product: phosphoheptose isomerase

Products: NA

Alternate protein names: Sedoheptulose 7-phosphate isomerase [H]

Number of amino acids: Translated: 194; Mature: 194

Protein sequence:

>194_residues
MYLDQIKAELVEAQDLLNKFISDENNIKLIQEAALLISNSFKQGGKVLSCGNGGSHCDAMHFAEELTGRYRENRPGYPAI
AISDASHLSCVSNDFGYEYVFSRYVEAVGQKGDVLFGLSTSGNSKNILNAIEAAKTKGMKVIAMTGKDGGKMAGLADVEI
RIPHFRYADRIQEIHIKVIHILMMLIEFEMAKQA

Sequences:

>Translated_194_residues
MYLDQIKAELVEAQDLLNKFISDENNIKLIQEAALLISNSFKQGGKVLSCGNGGSHCDAMHFAEELTGRYRENRPGYPAI
AISDASHLSCVSNDFGYEYVFSRYVEAVGQKGDVLFGLSTSGNSKNILNAIEAAKTKGMKVIAMTGKDGGKMAGLADVEI
RIPHFRYADRIQEIHIKVIHILMMLIEFEMAKQA
>Mature_194_residues
MYLDQIKAELVEAQDLLNKFISDENNIKLIQEAALLISNSFKQGGKVLSCGNGGSHCDAMHFAEELTGRYRENRPGYPAI
AISDASHLSCVSNDFGYEYVFSRYVEAVGQKGDVLFGLSTSGNSKNILNAIEAAKTKGMKVIAMTGKDGGKMAGLADVEI
RIPHFRYADRIQEIHIKVIHILMMLIEFEMAKQA

Specific function: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate [H]

COG id: COG0279

COG function: function code G; Phosphoheptose isomerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain [H]

Homologues:

Organism=Escherichia coli, GI1786416, Length=192, Percent_Identity=73.9583333333333, Blast_Score=302, Evalue=9e-84,
Organism=Escherichia coli, GI1789539, Length=162, Percent_Identity=45.0617283950617, Blast_Score=144, Evalue=5e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004515
- InterPro:   IPR020620
- InterPro:   IPR001347 [H]

Pfam domain/function: PF01380 SIS [H]

EC number: =5.3.1.28 [H]

Molecular weight: Translated: 21391; Mature: 21391

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYLDQIKAELVEAQDLLNKFISDENNIKLIQEAALLISNSFKQGGKVLSCGNGGSHCDAM
CCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHH
HFAEELTGRYRENRPGYPAIAISDASHLSCVSNDFGYEYVFSRYVEAVGQKGDVLFGLST
HHHHHHHHHHHCCCCCCCEEEECCCCHHHHHHCCCCHHHHHHHHHHHHCCCCCEEEEEEC
SGNSKNILNAIEAAKTKGMKVIAMTGKDGGKMAGLADVEIRIPHFRYADRIQEIHIKVIH
CCCCHHHHHHHHHHHHCCEEEEEEECCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHH
ILMMLIEFEMAKQA
HHHHHHHHHHHHCC
>Mature Secondary Structure
MYLDQIKAELVEAQDLLNKFISDENNIKLIQEAALLISNSFKQGGKVLSCGNGGSHCDAM
CCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHH
HFAEELTGRYRENRPGYPAIAISDASHLSCVSNDFGYEYVFSRYVEAVGQKGDVLFGLST
HHHHHHHHHHHCCCCCCCEEEECCCCHHHHHHCCCCHHHHHHHHHHHHCCCCCEEEEEEC
SGNSKNILNAIEAAKTKGMKVIAMTGKDGGKMAGLADVEIRIPHFRYADRIQEIHIKVIH
CCCCHHHHHHHHHHHHCCEEEEEEECCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHH
ILMMLIEFEMAKQA
HHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA