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The map label for this gene is queC [H]

Identifier: 148826200

GI number: 148826200

Start: 1209419

End: 1210102

Strand: Direct

Name: queC [H]

Synonym: CGSHiEE_06085

Alternate gene names: 148826200

Gene position: 1209419-1210102 (Clockwise)

Preceding gene: 148826198

Following gene: 148826201

Centisome position: 66.71

GC content: 37.28

Gene sequence:

>684_bases
ATGAATATTTTCAATCCAAACCACGATCGTAAAGCGATTGTCATCTTTTCTGGTGGACAAGACTCCACGACTTGTTTATT
CCAAGCTATTGCTGAATACGGCAAAGAAAACATAGAAGCCATTACCTTTCAATATGGGCAGCGTCATGCTATTGAGTTAG
AAAAGGCGCGCGCCATTGTGCAAGATTTAGGCATTAAACAAACCTTGATTGATACATCTGTTATGAAAGCTATCACGCAT
AATGCATTAATGGATGAACAAGCGCATATTGAGCAAAAAGAGAATGAATTGCCAAACACTTTTGTTGATGGTCGCAATGC
CCTATTTTTACTTTATGCCGCGATTTATGCGAAAGGCCAAGGCATTCAAGATATTATCACTGGCGTATGTGAAACAGATT
TCAGCGGTTATCCCGATTGCCGAGATGTGTTTATCAAGTCAATGAATGTCACATTAAATTTAGCTATGGATTATCAATTC
AATATCAAAACACCATTAATGTATCTCACTAAAGCCCAAACTTGGCAGCTTGCTGATGAATTAGGCGTATTAAATTATGT
ACAAAAACATACTCACACTTGCTATGAAGGCATCGAAGGTGGATGCGGAAAATGCCCAAGCTGTATTTTACGCAATAAAG
GTCTAAAGAAATATTTGACTCAAAAAGGTAGAAAAAATGTTTAA

Upstream 100 bases:

>100_bases
TCCAACGAAATATTTCACTTGTCTTGCTAAAATAGAACTTCCCCACTAGAATACCCCCCCGTAGTTCGCAAACCTCCTAC
AATAAAAAACTAGGTAAAAT

Downstream 100 bases:

>100_bases
AATTTCCAAAGAATTTAGCTTTGACATGGCACATTTATTAGATGGACATGATGGGAAATGTCAAAATTTACATGGACACA
CATATAAATTACAAGTTGAA

Product: PP-loop superfamily ATPase

Products: NA

Alternate protein names: 7-cyano-7-carbaguanine synthase; PreQ(0) synthase; Queuosine biosynthesis protein queC [H]

Number of amino acids: Translated: 227; Mature: 227

Protein sequence:

>227_residues
MNIFNPNHDRKAIVIFSGGQDSTTCLFQAIAEYGKENIEAITFQYGQRHAIELEKARAIVQDLGIKQTLIDTSVMKAITH
NALMDEQAHIEQKENELPNTFVDGRNALFLLYAAIYAKGQGIQDIITGVCETDFSGYPDCRDVFIKSMNVTLNLAMDYQF
NIKTPLMYLTKAQTWQLADELGVLNYVQKHTHTCYEGIEGGCGKCPSCILRNKGLKKYLTQKGRKNV

Sequences:

>Translated_227_residues
MNIFNPNHDRKAIVIFSGGQDSTTCLFQAIAEYGKENIEAITFQYGQRHAIELEKARAIVQDLGIKQTLIDTSVMKAITH
NALMDEQAHIEQKENELPNTFVDGRNALFLLYAAIYAKGQGIQDIITGVCETDFSGYPDCRDVFIKSMNVTLNLAMDYQF
NIKTPLMYLTKAQTWQLADELGVLNYVQKHTHTCYEGIEGGCGKCPSCILRNKGLKKYLTQKGRKNV
>Mature_227_residues
MNIFNPNHDRKAIVIFSGGQDSTTCLFQAIAEYGKENIEAITFQYGQRHAIELEKARAIVQDLGIKQTLIDTSVMKAITH
NALMDEQAHIEQKENELPNTFVDGRNALFLLYAAIYAKGQGIQDIITGVCETDFSGYPDCRDVFIKSMNVTLNLAMDYQF
NIKTPLMYLTKAQTWQLADELGVLNYVQKHTHTCYEGIEGGCGKCPSCILRNKGLKKYLTQKGRKNV

Specific function: Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) [H]

COG id: COG0603

COG function: function code R; Predicted PP-loop superfamily ATPase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the queC family [H]

Homologues:

Organism=Escherichia coli, GI1786648, Length=218, Percent_Identity=46.7889908256881, Blast_Score=206, Evalue=8e-55,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018317
- InterPro:   IPR014729 [H]

Pfam domain/function: PF06508 ExsB [H]

EC number: NA

Molecular weight: Translated: 25553; Mature: 25553

Theoretical pI: Translated: 7.07; Mature: 7.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.1 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
3.1 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIFNPNHDRKAIVIFSGGQDSTTCLFQAIAEYGKENIEAITFQYGQRHAIELEKARAIV
CCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHCHHHHEEEEEECCCCHHHHHHHHHHHH
QDLGIKQTLIDTSVMKAITHNALMDEQAHIEQKENELPNTFVDGRNALFLLYAAIYAKGQ
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCHHHHHHHHHHHHCCC
GIQDIITGVCETDFSGYPDCRDVFIKSMNVTLNLAMDYQFNIKTPLMYLTKAQTWQLADE
CHHHHHHHHHHCCCCCCCCHHHHHHHHCCEEEEEEEEEEECCCCCHHHHHCCHHHHHHHH
LGVLNYVQKHTHTCYEGIEGGCGKCPSCILRNKGLKKYLTQKGRKNV
HHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCHHHHHHHCCCCCC
>Mature Secondary Structure
MNIFNPNHDRKAIVIFSGGQDSTTCLFQAIAEYGKENIEAITFQYGQRHAIELEKARAIV
CCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHCHHHHEEEEEECCCCHHHHHHHHHHHH
QDLGIKQTLIDTSVMKAITHNALMDEQAHIEQKENELPNTFVDGRNALFLLYAAIYAKGQ
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCHHHHHHHHHHHHCCC
GIQDIITGVCETDFSGYPDCRDVFIKSMNVTLNLAMDYQFNIKTPLMYLTKAQTWQLADE
CHHHHHHHHHHCCCCCCCCHHHHHHHHCCEEEEEEEEEEECCCCCHHHHHCCHHHHHHHH
LGVLNYVQKHTHTCYEGIEGGCGKCPSCILRNKGLKKYLTQKGRKNV
HHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]