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The map label for this gene is mukE [H]

Identifier: 148825912

GI number: 148825912

Start: 924070

End: 924804

Strand: Direct

Name: mukE [H]

Synonym: CGSHiEE_04415

Alternate gene names: 148825912

Gene position: 924070-924804 (Clockwise)

Preceding gene: 148825911

Following gene: 148825913

Centisome position: 50.97

GC content: 40.54

Gene sequence:

>735_bases
ATGACAGACAACCTTCAAGATGTAATTTCCCCAAAACTCGCTGTGGCGATTGCAAATCCAATATTTCCAGCGGTGGATAG
CCTGTTACGTTCCGGTCGCCATATCAGCACGGAGCATTTAGATAATCACGCATTTTTAATGGATTTCCAAAATGAATTGG
ACGGTTTCTATCGCCGTTATAACGTGGAACTTATTCGTGCACCGGAAGGCTTTTTCTATCTTCGCCCGAAAGCAACGACA
TTAATTGCGCGTTCAGTACTTTCTGAGTTGGAAATGCTTGTTGGTAAAGTGCTTTGTTATCTTTATTTAAGCCCAGAACG
TTTAGCTCAACAAGGCATTTTTAGTACGCAAGAAGTGTATGATGAATTATTAAATCTTGCCGATGAAGGAAAATTATTAA
AAGCAGTTAATCAGCGTTCAAGTGGTTCTGACTTAGATAAACAAAAATTGGCAGAAAAAGTGCGGGCGGCAATTGGTCGT
TTACGTCGTTTAGGTATGATTCAAACTGTTGGCGAACAAAATAGTGGGAAATTTACGATTTCTGAATCTGTATTTCGTTT
TGGTGCGGAAGTGCGTAGCGGAGATGATCCATTAGAAGCACAAGCTCGACTTATTCGTGATGGAGAAGCGGCAACACCAG
AATCCTTAGCGTTGGAAAAACAAGCACAATTAATGGAAAACGATACGGAAAGTGCGGATGAAATTGACGAAGAATTTGAC
GGAGAACAAGAATAA

Upstream 100 bases:

>100_bases
TATGCCCAAACCCTCTTTAGCAAAGAGGGGCTAGGGGAGATTTGGCAATAATGATTAACGAAGAAAGTAACTGAATAAAG
TTTTAATAGAGAAATAACCT

Downstream 100 bases:

>100_bases
TGTCTGATGTTTTTGAATTAGAAAATGAAATCGAATTAGAGAGCGATGAAGTCATTATGGAAAATGAAAACGTCGAAGAA
ATCGTTGAAGCACCTATGCC

Product: condesin subunit E

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 244; Mature: 243

Protein sequence:

>244_residues
MTDNLQDVISPKLAVAIANPIFPAVDSLLRSGRHISTEHLDNHAFLMDFQNELDGFYRRYNVELIRAPEGFFYLRPKATT
LIARSVLSELEMLVGKVLCYLYLSPERLAQQGIFSTQEVYDELLNLADEGKLLKAVNQRSSGSDLDKQKLAEKVRAAIGR
LRRLGMIQTVGEQNSGKFTISESVFRFGAEVRSGDDPLEAQARLIRDGEAATPESLALEKQAQLMENDTESADEIDEEFD
GEQE

Sequences:

>Translated_244_residues
MTDNLQDVISPKLAVAIANPIFPAVDSLLRSGRHISTEHLDNHAFLMDFQNELDGFYRRYNVELIRAPEGFFYLRPKATT
LIARSVLSELEMLVGKVLCYLYLSPERLAQQGIFSTQEVYDELLNLADEGKLLKAVNQRSSGSDLDKQKLAEKVRAAIGR
LRRLGMIQTVGEQNSGKFTISESVFRFGAEVRSGDDPLEAQARLIRDGEAATPESLALEKQAQLMENDTESADEIDEEFD
GEQE
>Mature_243_residues
TDNLQDVISPKLAVAIANPIFPAVDSLLRSGRHISTEHLDNHAFLMDFQNELDGFYRRYNVELIRAPEGFFYLRPKATTL
IARSVLSELEMLVGKVLCYLYLSPERLAQQGIFSTQEVYDELLNLADEGKLLKAVNQRSSGSDLDKQKLAEKVRAAIGRL
RRLGMIQTVGEQNSGKFTISESVFRFGAEVRSGDDPLEAQARLIRDGEAATPESLALEKQAQLMENDTESADEIDEEFDG
EQE

Specific function: Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interactio

COG id: COG3095

COG function: function code D; Uncharacterized protein involved in chromosome partitioning

Gene ontology:

Cell location: Cytoplasm, nucleoid. Note=Restricted to the nucleoid region (By similarity) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mukE family [H]

Homologues:

Organism=Escherichia coli, GI226510932, Length=233, Percent_Identity=66.9527896995708, Blast_Score=316, Evalue=9e-88,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007385 [H]

Pfam domain/function: PF04288 MukE [H]

EC number: NA

Molecular weight: Translated: 27342; Mature: 27211

Theoretical pI: Translated: 4.43; Mature: 4.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDNLQDVISPKLAVAIANPIFPAVDSLLRSGRHISTEHLDNHAFLMDFQNELDGFYRRY
CCCCHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCHHEEHHHHHHHHHHHHH
NVELIRAPEGFFYLRPKATTLIARSVLSELEMLVGKVLCYLYLSPERLAQQGIFSTQEVY
CEEEEECCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCHHHHH
DELLNLADEGKLLKAVNQRSSGSDLDKQKLAEKVRAAIGRLRRLGMIQTVGEQNSGKFTI
HHHHHHHCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEH
SESVFRFGAEVRSGDDPLEAQARLIRDGEAATPESLALEKQAQLMENDTESADEIDEEFD
HHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHCC
GEQE
CCCC
>Mature Secondary Structure 
TDNLQDVISPKLAVAIANPIFPAVDSLLRSGRHISTEHLDNHAFLMDFQNELDGFYRRY
CCCHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCHHEEHHHHHHHHHHHHH
NVELIRAPEGFFYLRPKATTLIARSVLSELEMLVGKVLCYLYLSPERLAQQGIFSTQEVY
CEEEEECCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCHHHHH
DELLNLADEGKLLKAVNQRSSGSDLDKQKLAEKVRAAIGRLRRLGMIQTVGEQNSGKFTI
HHHHHHHCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEH
SESVFRFGAEVRSGDDPLEAQARLIRDGEAATPESLALEKQAQLMENDTESADEIDEEFD
HHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHCC
GEQE
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]