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The map label for this gene is mukF

Identifier: 148825911

GI number: 148825911

Start: 922587

End: 923921

Strand: Direct

Name: mukF

Synonym: CGSHiEE_04410

Alternate gene names: 148825911

Gene position: 922587-923921 (Clockwise)

Preceding gene: 148825906

Following gene: 148825912

Centisome position: 50.89

GC content: 39.1

Gene sequence:

>1335_bases
ATGATTGAAACATCCCAAACTATTCCTGAACTCGTCTCTTGGGCAAAAGATCGCGAGTTTTCTTTGAATTTACCTACCGA
GCGCTTGGTTTTCCTGCTGGCGATTGCAATTTATAACAACGAACGTTTAGACGGCGAAATGTTAGAAGCCGATCTTGTGG
ATATTTTCCGCCACACGATGAATGCTTTTGAGCAATCCACCGATGCCATTGCAACACGAGCGAATAATGCAATTAATGAA
TTAGTGAAACAACGTTTGTTAAATCGTTTTAGTAGCGAATTTACTGAGGGCTTGGCGATTTATCGTTTAACGCCATTAGG
TGTTGGCGTGTCTGATTATTACATTCGTCAGCGTGAATTTTCCGCATTGCGTCTTTCAGTGCAACTTTCCATTGTGGCAG
ATGAAATTCAACGCGCTTCTGATTCTGCAGAAGAAGGCGTGGAGAATAATGAAAGTGAACATTATTGGCGTCGTAATGTA
TTTGCGCCATTAAAATATTCCGTTGCAGAGATTTTTGATAGCATCGATCTTTCACAACGTATTATGGATGAAAATCAGCA
AAGTATTAAAGATGAAATTGCAGAGCTTCTTACTAAAGATTGGCAAGCGGCAATTTCAAGCTGTGAACGTTTATTAGATG
AAACATCAGGGAATTTGCGTGAATTGCAAGATACGCTAAATGCCGCGGGGGATAAACTTCAAGCACAATTATTGCGTATT
CAAGATTGTGTGATCGGGCGTGATGATTTGTATTTTATCGATCAATTAATTACCGATTTACAATCTAAACTTGACCGAAT
TATTAGCTGGGGACAACAAGCCATCGATTTATGGATTGGTTATGACCGCCATGTGCATAAATTTATCCGAACTGCCATTG
ATATGGATAAAAATCGCGTGTTTTCACAACGTTTACGTAATTCTATTCATAATTATTTTGAGCATCCTTGGTTCTTATGG
ACAGCGCAAGCTGAGCGTTTAGTCGATCTGCGTGATGAAGAAATGGTGTTGCGTGAAGATGATGCTTTAGGTGAATTGCC
AGAAGAATTGCAATACGAATCCCTTTCAGATTTACATGATCAAATTGTAGAGCATATGCAAGACTTACTGATTGCTTATC
GTGAAAATAACCGTCCGATTGATTTGAGTTTAGTGTTAAAAGAACAACTGGAAAATTATCCACTTTCTCGTCATTTTGAT
GTGGCTCGAATCATTGTTGATCAAGCCGTACGCCTTGGTATGGCGAATGATGATTTATCGGGTATTTATCCAGATTGGCA
AGTAATTAATAAACGTGGCGCAGAAGTTCAAGCGCATGTGATTGATAAGTATTGA

Upstream 100 bases:

>100_bases
AGGAAAAGTGCGGTCAATTCAAAAGAAGATTTTTAAGATCCGTAAAAAATCCTGTATAATCTTTCCAATTTTTTGTTCAA
TTTTAACGCTTTGCAATTCA

Downstream 100 bases:

>100_bases
TTTTAAGATAATTTAAAAGCTAATTTCGACGGAATTACTTCTGTTAAATATGCCCAAACCCTCTTTAGCAAAGAGGGGCT
AGGGGAGATTTGGCAATAAT

Product: condesin subunit F

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 444; Mature: 444

Protein sequence:

>444_residues
MIETSQTIPELVSWAKDREFSLNLPTERLVFLLAIAIYNNERLDGEMLEADLVDIFRHTMNAFEQSTDAIATRANNAINE
LVKQRLLNRFSSEFTEGLAIYRLTPLGVGVSDYYIRQREFSALRLSVQLSIVADEIQRASDSAEEGVENNESEHYWRRNV
FAPLKYSVAEIFDSIDLSQRIMDENQQSIKDEIAELLTKDWQAAISSCERLLDETSGNLRELQDTLNAAGDKLQAQLLRI
QDCVIGRDDLYFIDQLITDLQSKLDRIISWGQQAIDLWIGYDRHVHKFIRTAIDMDKNRVFSQRLRNSIHNYFEHPWFLW
TAQAERLVDLRDEEMVLREDDALGELPEELQYESLSDLHDQIVEHMQDLLIAYRENNRPIDLSLVLKEQLENYPLSRHFD
VARIIVDQAVRLGMANDDLSGIYPDWQVINKRGAEVQAHVIDKY

Sequences:

>Translated_444_residues
MIETSQTIPELVSWAKDREFSLNLPTERLVFLLAIAIYNNERLDGEMLEADLVDIFRHTMNAFEQSTDAIATRANNAINE
LVKQRLLNRFSSEFTEGLAIYRLTPLGVGVSDYYIRQREFSALRLSVQLSIVADEIQRASDSAEEGVENNESEHYWRRNV
FAPLKYSVAEIFDSIDLSQRIMDENQQSIKDEIAELLTKDWQAAISSCERLLDETSGNLRELQDTLNAAGDKLQAQLLRI
QDCVIGRDDLYFIDQLITDLQSKLDRIISWGQQAIDLWIGYDRHVHKFIRTAIDMDKNRVFSQRLRNSIHNYFEHPWFLW
TAQAERLVDLRDEEMVLREDDALGELPEELQYESLSDLHDQIVEHMQDLLIAYRENNRPIDLSLVLKEQLENYPLSRHFD
VARIIVDQAVRLGMANDDLSGIYPDWQVINKRGAEVQAHVIDKY
>Mature_444_residues
MIETSQTIPELVSWAKDREFSLNLPTERLVFLLAIAIYNNERLDGEMLEADLVDIFRHTMNAFEQSTDAIATRANNAINE
LVKQRLLNRFSSEFTEGLAIYRLTPLGVGVSDYYIRQREFSALRLSVQLSIVADEIQRASDSAEEGVENNESEHYWRRNV
FAPLKYSVAEIFDSIDLSQRIMDENQQSIKDEIAELLTKDWQAAISSCERLLDETSGNLRELQDTLNAAGDKLQAQLLRI
QDCVIGRDDLYFIDQLITDLQSKLDRIISWGQQAIDLWIGYDRHVHKFIRTAIDMDKNRVFSQRLRNSIHNYFEHPWFLW
TAQAERLVDLRDEEMVLREDDALGELPEELQYESLSDLHDQIVEHMQDLLIAYRENNRPIDLSLVLKEQLENYPLSRHFD
VARIIVDQAVRLGMANDDLSGIYPDWQVINKRGAEVQAHVIDKY

Specific function: Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid

COG id: COG3006

COG function: function code D; Uncharacterized protein involved in chromosome partitioning

Gene ontology:

Cell location: Cytoplasm, nucleoid. Note=Restricted to the nucleoid region (By similarity)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mukF family

Homologues:

Organism=Escherichia coli, GI1787152, Length=444, Percent_Identity=66.2162162162162, Blast_Score=619, Evalue=1e-178,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MUKF_HAEIE (A5UBY0)

Other databases:

- EMBL:   CP000671
- RefSeq:   YP_001290664.1
- ProteinModelPortal:   A5UBY0
- SMR:   A5UBY0
- STRING:   A5UBY0
- GeneID:   5225106
- GenomeReviews:   CP000671_GR
- KEGG:   hip:CGSHiEE_04410
- eggNOG:   COG3006
- HOGENOM:   HBG296836
- OMA:   NRFSSEF
- ProtClustDB:   PRK05260
- BioCyc:   HINF374930:CGSHIEE_04410-MONOMER
- GO:   GO:0005737
- GO:   GO:0009295
- HAMAP:   MF_01803
- InterPro:   IPR005582
- PIRSF:   PIRSF018282

Pfam domain/function: PF03882 KicB

EC number: NA

Molecular weight: Translated: 51608; Mature: 51608

Theoretical pI: Translated: 4.39; Mature: 4.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIETSQTIPELVSWAKDREFSLNLPTERLVFLLAIAIYNNERLDGEMLEADLVDIFRHTM
CCCCHHHHHHHHHHHCCCCEECCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
NAFEQSTDAIATRANNAINELVKQRLLNRFSSEFTEGLAIYRLTPLGVGVSDYYIRQREF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCHHHHHHHHHHH
SALRLSVQLSIVADEIQRASDSAEEGVENNESEHYWRRNVFAPLKYSVAEIFDSIDLSQR
HHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
IMDENQQSIKDEIAELLTKDWQAAISSCERLLDETSGNLRELQDTLNAAGDKLQAQLLRI
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHH
QDCVIGRDDLYFIDQLITDLQSKLDRIISWGQQAIDLWIGYDRHVHKFIRTAIDMDKNRV
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCHHHHH
FSQRLRNSIHNYFEHPWFLWTAQAERLVDLRDEEMVLREDDALGELPEELQYESLSDLHD
HHHHHHHHHHHHHCCCEEEEECCHHHHHHCCCCHHHHHCCCHHHCCHHHHHHHHHHHHHH
QIVEHMQDLLIAYRENNRPIDLSLVLKEQLENYPLSRHFDVARIIVDQAVRLGMANDDLS
HHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCC
GIYPDWQVINKRGAEVQAHVIDKY
CCCCCHHHHHCCCCEEEEHCCCCC
>Mature Secondary Structure
MIETSQTIPELVSWAKDREFSLNLPTERLVFLLAIAIYNNERLDGEMLEADLVDIFRHTM
CCCCHHHHHHHHHHHCCCCEECCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
NAFEQSTDAIATRANNAINELVKQRLLNRFSSEFTEGLAIYRLTPLGVGVSDYYIRQREF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCHHHHHHHHHHH
SALRLSVQLSIVADEIQRASDSAEEGVENNESEHYWRRNVFAPLKYSVAEIFDSIDLSQR
HHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
IMDENQQSIKDEIAELLTKDWQAAISSCERLLDETSGNLRELQDTLNAAGDKLQAQLLRI
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHH
QDCVIGRDDLYFIDQLITDLQSKLDRIISWGQQAIDLWIGYDRHVHKFIRTAIDMDKNRV
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCHHHHH
FSQRLRNSIHNYFEHPWFLWTAQAERLVDLRDEEMVLREDDALGELPEELQYESLSDLHD
HHHHHHHHHHHHHCCCEEEEECCHHHHHHCCCCHHHHHCCCHHHCCHHHHHHHHHHHHHH
QIVEHMQDLLIAYRENNRPIDLSLVLKEQLENYPLSRHFDVARIIVDQAVRLGMANDDLS
HHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCC
GIYPDWQVINKRGAEVQAHVIDKY
CCCCCHHHHHCCCCEEEEHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA