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The map label for this gene is moaE [H]

Identifier: 148825788

GI number: 148825788

Start: 756585

End: 757037

Strand: Direct

Name: moaE [H]

Synonym: CGSHiEE_03695

Alternate gene names: 148825788

Gene position: 756585-757037 (Clockwise)

Preceding gene: 148825787

Following gene: 148825791

Centisome position: 41.73

GC content: 39.96

Gene sequence:

>453_bases
ATGACGGATATTCAAATTGCGGTACAAGAACAGTCGTTTGATCAAAATGCGGTTTATCAATGGCTTTCTGAACTACATTC
GGTTGGTGCAACGGTTATATTTGTTGGTAAAGTACGCGATCTTAATTTAGGCAATGCAGTATCTAGTTTGTACCTAGAAC
ATTACCCTGCAATGACTGAAAAAGCGTTGAATGAAATTGTTGCACAAGCGAAAGCCCGTTGGGATATTCAACGTGTATCG
GTAATTCATCGTGTTGGGCTTTTACAAACTGGTGATGAAATTGTGTTGGTGGGGGTAAGTTCCGCACATCGTGGAGATGC
TTATCACGCCAATGAATTCATTATGGATTTTCTAAAATCCAAAGCTCCGTTCTGGAAAAAAGAACAAACCAATCAAGGCG
AGCGTTGGATTGAAGCAAGAGAGAGCGATAAAGAAGCATTAGAAAAATGGTAA

Upstream 100 bases:

>100_bases
CAAACTTTTAGTAGCGATTAATCAAACCTTGATGCCGTTAGAAAGTGCGGTCAAAAATGGCGATGAAATTGCTTTTTTCC
CACCCGTAACAGGGGGCTAA

Downstream 100 bases:

>100_bases
TCGCTTACCTGCACCCTAATTCATTAAGGTGCAGATTAAATATTTTCATTTATGTTATTTTGATAACGCACCACTTCCCC
AAGTTTGCACTTCTTCAGGG

Product: molybdopterin converting factor subunit 2

Products: NA

Alternate protein names: MPT synthase subunit 2; Molybdenum cofactor biosynthesis protein E; Molybdopterin-converting factor large subunit; Molybdopterin-converting factor subunit 2 [H]

Number of amino acids: Translated: 150; Mature: 149

Protein sequence:

>150_residues
MTDIQIAVQEQSFDQNAVYQWLSELHSVGATVIFVGKVRDLNLGNAVSSLYLEHYPAMTEKALNEIVAQAKARWDIQRVS
VIHRVGLLQTGDEIVLVGVSSAHRGDAYHANEFIMDFLKSKAPFWKKEQTNQGERWIEARESDKEALEKW

Sequences:

>Translated_150_residues
MTDIQIAVQEQSFDQNAVYQWLSELHSVGATVIFVGKVRDLNLGNAVSSLYLEHYPAMTEKALNEIVAQAKARWDIQRVS
VIHRVGLLQTGDEIVLVGVSSAHRGDAYHANEFIMDFLKSKAPFWKKEQTNQGERWIEARESDKEALEKW
>Mature_149_residues
TDIQIAVQEQSFDQNAVYQWLSELHSVGATVIFVGKVRDLNLGNAVSSLYLEHYPAMTEKALNEIVAQAKARWDIQRVSV
IHRVGLLQTGDEIVLVGVSSAHRGDAYHANEFIMDFLKSKAPFWKKEQTNQGERWIEARESDKEALEKW

Specific function: Converts molybdopterin precursor Z into molybdopterin. This requires the incorporation of two sulfur atoms into precursor Z to generate a dithiolene group. The sulfur is provided by moaD [H]

COG id: COG0314

COG function: function code H; Molybdopterin converting factor, large subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaE family [H]

Homologues:

Organism=Homo sapiens, GI4758732, Length=109, Percent_Identity=34.8623853211009, Blast_Score=83, Evalue=1e-16,
Organism=Escherichia coli, GI1787003, Length=150, Percent_Identity=56.6666666666667, Blast_Score=186, Evalue=5e-49,
Organism=Caenorhabditis elegans, GI17509279, Length=133, Percent_Identity=33.8345864661654, Blast_Score=77, Evalue=3e-15,
Organism=Drosophila melanogaster, GI21356259, Length=128, Percent_Identity=33.59375, Blast_Score=82, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003448 [H]

Pfam domain/function: PF02391 MoaE [H]

EC number: NA

Molecular weight: Translated: 17086; Mature: 16955

Theoretical pI: Translated: 5.60; Mature: 5.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDIQIAVQEQSFDQNAVYQWLSELHSVGATVIFVGKVRDLNLGNAVSSLYLEHYPAMTE
CCCEEEEEECCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHCCHHHH
KALNEIVAQAKARWDIQRVSVIHRVGLLQTGDEIVLVGVSSAHRGDAYHANEFIMDFLKS
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHC
KAPFWKKEQTNQGERWIEARESDKEALEKW
CCCCCCCCCCCCHHHHHHHHCCHHHHHHCC
>Mature Secondary Structure 
TDIQIAVQEQSFDQNAVYQWLSELHSVGATVIFVGKVRDLNLGNAVSSLYLEHYPAMTE
CCEEEEEECCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHCCHHHH
KALNEIVAQAKARWDIQRVSVIHRVGLLQTGDEIVLVGVSSAHRGDAYHANEFIMDFLKS
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHC
KAPFWKKEQTNQGERWIEARESDKEALEKW
CCCCCCCCCCCCHHHHHHHHCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]