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The map label for this gene is uvrC [H]

Identifier: 148825664

GI number: 148825664

Start: 607819

End: 609648

Strand: Direct

Name: uvrC [H]

Synonym: CGSHiEE_03020

Alternate gene names: 148825664

Gene position: 607819-609648 (Clockwise)

Preceding gene: 148825663

Following gene: 148825665

Centisome position: 33.52

GC content: 39.56

Gene sequence:

>1830_bases
ATGTTCAATTACAAAAAATTCCTCGCTGATGTCTCTCACGAACCTGGTGTTTATCGTATGTATGATGATAAAGATCAGGT
TATTTATGTTGGGAAAGCAAAGGATCTAAAAAAACGTCTTTCAAGCTATTTTCGTAAAAACCTGAGCAGTAAAAAAACAG
AGGCGTTGGTGGCATCAATTCATCATATTGACACCATGCTAACTTCATCTGAAACGGAAGCTTTGCTGCTAGAGCATAAT
TTTATCAAGCTTTATCAGCCTCGCTATAACGTATTATTGCGTGATGATAAATCCTATCCATTTATTTTATTAACCAAAGA
ACGTCACCCAAGAATCACTTCCTATCGTGGGTCTAAAAAATTTGCCGGTGAATATTTCGGGCCTTATCCTCATGCGGGAG
CCGTGCGTGAAACTTTATCGCTTTTGCAAAAACTTTTCCCTGTTCGACAATGTGAAAATTCCGTTTATTCCAACCGCTCT
CGTCCTTGTTTGCAATATCAAATTGGGCGTTGTTCTGCACCTTGTGTACAGGGATATGTTTCTGATGAAGAATATAATCA
GCAAGTTGAATTAGCCCGTTTATTTTTACAAGGCAAAGATCAACTGGTGTTAGATTATTTAATCGGGAAAATGGAGCAGG
CAAGCAGAAATTTAGATTTTGAACAGGCGGCTCGTTATCGCGATCAAATTCAGGCGGTGCGTTCGGTTATTGAAAAACAA
TTTGTATCCAATGAACGTTTAGATGATATGGATATTATGTCCATCGCTTACCAACACGGTTTAGCCTGTGTACAGGTGAT
GTTTATTCGTCAAGGAAAAGTGCTAGGCAATCGCAGTTATTTCCCAAAAGTCCCCGCCAATACGGATTTATCGGAACTTA
CCGAAACTTTTGTGGGGCAATTTTATTTACAAGGTCATCAAGGACGAAGTATCCCGAATAGCATTATTGTCGATCGTCAA
TTAGCTGAAAAATCAGAGCTTGAGCAACTTCTTACGGATCAAGCTGGCAGAAAAGTGACGATTCAAGAAAGCGTAAAAGG
CGATAAGAGTAAATATTTACAGCTCGCACAGGTTAATGCTAAAGCGGCCTTAAATGTACAACTTAAACAATCTTCACGAA
TGTCAGAGCGTTATCAAGCGTTGTGTGATCTGTTAAATCTCCCTGAAATTAAGCGTATGGAGTGTTTCGATATAAGCCAC
ACGATGGGAAATCAAACGGTAGCATCTTGTGTTGTTTTTAATCAAGAAGGCCCACTGAAATCTGATTATCGTCGTTTTAA
TATTGAAGGCATTACTGGTGGGGATGATTATGCAGCAATGGAACAAGCGTTGCAGAAACGTTATGAGCGTGATTTAGAAG
AAGATAAAATTCCCGATATTATTTTTATTGATGGTGGAAAAGGGCAATTAAATCGTGCGCTGAACGTGTTCCAACATCTT
CAAGTAAAATGGGATAAAAATAGACCGCACTTAATTGGCGTGGCAAAAGGTGTGGATCGTCGAGCAGGGCAGGAAGTACT
GATCATCAGCAAACAAGAGCGCGAAATTCATTTGCCTGATGATAGTTTGGCATTGCATTTGATTCAACACATCCGTGATG
AAAGTCATAATCACGCCATAAGCGGACACCGTAAAAAACGTCAAAAAGCCTTTACACAAAGTGGTTTAGAAACTATTGAA
GGTGTGGGCGCTAAACGTCGTCAGGCTTTACTGAAATATCTTGGCGGTTTACAAGGTGTGAAAAAGGCGACCTTAGATGA
AATAGCCTCTGTACCAGGAATTTCCCTTAAACTTGCTGAAACGATTTTTGAAACGCTCAAAAACGATTAA

Upstream 100 bases:

>100_bases
GGGGATAAATTTAACATCGCAAGCCTCCTTCAGCCCTTTAGGCTCCTTCCCTCGAAAGCAGGGGAAGGCAAGATGTCTTT
TGTTATTGGTAAAATATTCT

Downstream 100 bases:

>100_bases
TCAATTATCTCTTAAATGTAAATAACGATTGCTTTTCATCAGAAAGCCATTATGATCCGAACTTTCGGATCTATTTAACT
CTATTATAGGAAAAATTATG

Product: excinuclease ABC subunit C

Products: NA

Alternate protein names: Protein uvrC; Excinuclease ABC subunit C [H]

Number of amino acids: Translated: 609; Mature: 609

Protein sequence:

>609_residues
MFNYKKFLADVSHEPGVYRMYDDKDQVIYVGKAKDLKKRLSSYFRKNLSSKKTEALVASIHHIDTMLTSSETEALLLEHN
FIKLYQPRYNVLLRDDKSYPFILLTKERHPRITSYRGSKKFAGEYFGPYPHAGAVRETLSLLQKLFPVRQCENSVYSNRS
RPCLQYQIGRCSAPCVQGYVSDEEYNQQVELARLFLQGKDQLVLDYLIGKMEQASRNLDFEQAARYRDQIQAVRSVIEKQ
FVSNERLDDMDIMSIAYQHGLACVQVMFIRQGKVLGNRSYFPKVPANTDLSELTETFVGQFYLQGHQGRSIPNSIIVDRQ
LAEKSELEQLLTDQAGRKVTIQESVKGDKSKYLQLAQVNAKAALNVQLKQSSRMSERYQALCDLLNLPEIKRMECFDISH
TMGNQTVASCVVFNQEGPLKSDYRRFNIEGITGGDDYAAMEQALQKRYERDLEEDKIPDIIFIDGGKGQLNRALNVFQHL
QVKWDKNRPHLIGVAKGVDRRAGQEVLIISKQEREIHLPDDSLALHLIQHIRDESHNHAISGHRKKRQKAFTQSGLETIE
GVGAKRRQALLKYLGGLQGVKKATLDEIASVPGISLKLAETIFETLKND

Sequences:

>Translated_609_residues
MFNYKKFLADVSHEPGVYRMYDDKDQVIYVGKAKDLKKRLSSYFRKNLSSKKTEALVASIHHIDTMLTSSETEALLLEHN
FIKLYQPRYNVLLRDDKSYPFILLTKERHPRITSYRGSKKFAGEYFGPYPHAGAVRETLSLLQKLFPVRQCENSVYSNRS
RPCLQYQIGRCSAPCVQGYVSDEEYNQQVELARLFLQGKDQLVLDYLIGKMEQASRNLDFEQAARYRDQIQAVRSVIEKQ
FVSNERLDDMDIMSIAYQHGLACVQVMFIRQGKVLGNRSYFPKVPANTDLSELTETFVGQFYLQGHQGRSIPNSIIVDRQ
LAEKSELEQLLTDQAGRKVTIQESVKGDKSKYLQLAQVNAKAALNVQLKQSSRMSERYQALCDLLNLPEIKRMECFDISH
TMGNQTVASCVVFNQEGPLKSDYRRFNIEGITGGDDYAAMEQALQKRYERDLEEDKIPDIIFIDGGKGQLNRALNVFQHL
QVKWDKNRPHLIGVAKGVDRRAGQEVLIISKQEREIHLPDDSLALHLIQHIRDESHNHAISGHRKKRQKAFTQSGLETIE
GVGAKRRQALLKYLGGLQGVKKATLDEIASVPGISLKLAETIFETLKND
>Mature_609_residues
MFNYKKFLADVSHEPGVYRMYDDKDQVIYVGKAKDLKKRLSSYFRKNLSSKKTEALVASIHHIDTMLTSSETEALLLEHN
FIKLYQPRYNVLLRDDKSYPFILLTKERHPRITSYRGSKKFAGEYFGPYPHAGAVRETLSLLQKLFPVRQCENSVYSNRS
RPCLQYQIGRCSAPCVQGYVSDEEYNQQVELARLFLQGKDQLVLDYLIGKMEQASRNLDFEQAARYRDQIQAVRSVIEKQ
FVSNERLDDMDIMSIAYQHGLACVQVMFIRQGKVLGNRSYFPKVPANTDLSELTETFVGQFYLQGHQGRSIPNSIIVDRQ
LAEKSELEQLLTDQAGRKVTIQESVKGDKSKYLQLAQVNAKAALNVQLKQSSRMSERYQALCDLLNLPEIKRMECFDISH
TMGNQTVASCVVFNQEGPLKSDYRRFNIEGITGGDDYAAMEQALQKRYERDLEEDKIPDIIFIDGGKGQLNRALNVFQHL
QVKWDKNRPHLIGVAKGVDRRAGQEVLIISKQEREIHLPDDSLALHLIQHIRDESHNHAISGHRKKRQKAFTQSGLETIE
GVGAKRRQALLKYLGGLQGVKKATLDEIASVPGISLKLAETIFETLKND

Specific function: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision [H]

COG id: COG0322

COG function: function code L; Nuclease subunit of the excinuclease complex

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 UVR domain [H]

Homologues:

Organism=Escherichia coli, GI87081999, Length=607, Percent_Identity=65.0741350906096, Blast_Score=833, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003583
- InterPro:   IPR010994
- InterPro:   IPR001943
- InterPro:   IPR009055
- InterPro:   IPR004791
- InterPro:   IPR001162
- InterPro:   IPR000305 [H]

Pfam domain/function: PF01541 GIY-YIG; PF02151 UVR; PF08459 UvrC_HhH_N [H]

EC number: NA

Molecular weight: Translated: 69603; Mature: 69603

Theoretical pI: Translated: 9.16; Mature: 9.16

Prosite motif: PS50151 UVR ; PS50164 UVRC_1 ; PS50165 UVRC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFNYKKFLADVSHEPGVYRMYDDKDQVIYVGKAKDLKKRLSSYFRKNLSSKKTEALVASI
CCCHHHHHHHCCCCCCEEEEECCCCCEEEEECHHHHHHHHHHHHHHHCCCHHHHHHHHHH
HHIDTMLTSSETEALLLEHNFIKLYQPRYNVLLRDDKSYPFILLTKERHPRITSYRGSKK
HHHHHHHCCCCCCEEEEECCHHEEECCCCCEEEECCCCCCEEEEECCCCCCCCCCCCCCH
FAGEYFGPYPHAGAVRETLSLLQKLFPVRQCENSVYSNRSRPCLQYQIGRCSAPCVQGYV
HCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHEECCCCCCHHHHCCC
SDEEYNQQVELARLFLQGKDQLVLDYLIGKMEQASRNLDFEQAARYRDQIQAVRSVIEKQ
CCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
FVSNERLDDMDIMSIAYQHGLACVQVMFIRQGKVLGNRSYFPKVPANTDLSELTETFVGQ
HHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCCCCCCCHHHHHHHHHHH
FYLQGHQGRSIPNSIIVDRQLAEKSELEQLLTDQAGRKVTIQESVKGDKSKYLQLAQVNA
HHEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHCCCHHHHHHHHHCCC
KAALNVQLKQSSRMSERYQALCDLLNLPEIKRMECFDISHTMGNQTVASCVVFNQEGPLK
CEEEEEEEHHHHHHHHHHHHHHHHHCCCCCCCCHHEEHHHHCCCHHEEHEEEECCCCCCC
SDYRRFNIEGITGGDDYAAMEQALQKRYERDLEEDKIPDIIFIDGGKGQLNRALNVFQHL
CCCCEEEEEEECCCCHHHHHHHHHHHHHHHCCHHCCCCCEEEEECCCHHHHHHHHHHHHH
QVKWDKNRPHLIGVAKGVDRRAGQEVLIISKQEREIHLPDDSLALHLIQHIRDESHNHAI
HEEECCCCCEEEEEECCCCHHCCCEEEEEEECCCEEECCCHHHHHHHHHHHHCCCCCCCC
SGHRKKRQKAFTQSGLETIEGVGAKRRQALLKYLGGLQGVKKATLDEIASVPGISLKLAE
CCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCHHHHHH
TIFETLKND
HHHHHHCCC
>Mature Secondary Structure
MFNYKKFLADVSHEPGVYRMYDDKDQVIYVGKAKDLKKRLSSYFRKNLSSKKTEALVASI
CCCHHHHHHHCCCCCCEEEEECCCCCEEEEECHHHHHHHHHHHHHHHCCCHHHHHHHHHH
HHIDTMLTSSETEALLLEHNFIKLYQPRYNVLLRDDKSYPFILLTKERHPRITSYRGSKK
HHHHHHHCCCCCCEEEEECCHHEEECCCCCEEEECCCCCCEEEEECCCCCCCCCCCCCCH
FAGEYFGPYPHAGAVRETLSLLQKLFPVRQCENSVYSNRSRPCLQYQIGRCSAPCVQGYV
HCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHEECCCCCCHHHHCCC
SDEEYNQQVELARLFLQGKDQLVLDYLIGKMEQASRNLDFEQAARYRDQIQAVRSVIEKQ
CCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
FVSNERLDDMDIMSIAYQHGLACVQVMFIRQGKVLGNRSYFPKVPANTDLSELTETFVGQ
HHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCCCCCCCHHHHHHHHHHH
FYLQGHQGRSIPNSIIVDRQLAEKSELEQLLTDQAGRKVTIQESVKGDKSKYLQLAQVNA
HHEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHCCCHHHHHHHHHCCC
KAALNVQLKQSSRMSERYQALCDLLNLPEIKRMECFDISHTMGNQTVASCVVFNQEGPLK
CEEEEEEEHHHHHHHHHHHHHHHHHCCCCCCCCHHEEHHHHCCCHHEEHEEEECCCCCCC
SDYRRFNIEGITGGDDYAAMEQALQKRYERDLEEDKIPDIIFIDGGKGQLNRALNVFQHL
CCCCEEEEEEECCCCHHHHHHHHHHHHHHHCCHHCCCCCEEEEECCCHHHHHHHHHHHHH
QVKWDKNRPHLIGVAKGVDRRAGQEVLIISKQEREIHLPDDSLALHLIQHIRDESHNHAI
HEEECCCCCEEEEEECCCCHHCCCEEEEEEECCCEEECCCHHHHHHHHHHHHCCCCCCCC
SGHRKKRQKAFTQSGLETIEGVGAKRRQALLKYLGGLQGVKKATLDEIASVPGISLKLAE
CCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCHHHHHH
TIFETLKND
HHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA