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The map label for this gene is lpxK [H]

Identifier: 148825661

GI number: 148825661

Start: 605840

End: 606838

Strand: Direct

Name: lpxK [H]

Synonym: CGSHiEE_03005

Alternate gene names: 148825661

Gene position: 605840-606838 (Clockwise)

Preceding gene: 148825660

Following gene: 148825662

Centisome position: 33.42

GC content: 40.04

Gene sequence:

>999_bases
ATGCCCTTCTGGTATTCCAATTCCAAACTTATTTGGCTCTTATCGCCTTTTTCTTTATTGTTTTGGTTGATTAGCCAACT
TCGTCACGCCTTATTTTGTTTGGGGATAAAATCTTCTTATCGCGCACCAAAACCAGTGATAATTGTGGGAAATTTGTCTG
TTGGTGGAAATGGCAAAACGCCCGTGGTGGTGTGGCTTGTGGAAGAATTAAAAAAACGAGGTTTGCGCGTAGGTGTGATT
TCTCGTGGTTACGGCAGTAAATCTAAAACTTATCCGTTATTCGTCACTGAAAATACGCGTCCGATTGAAGGTGGCGATGA
GCCAGTATTGATCGCTAAACGCACCAATGCGCCAGTCGTGATTTCCCCGAATCGCCAGCAAGCGATTGAATTACTCTTAA
GCCAAGCAGAGTGCGATATTATTGTTTCTGACGATGGTTTACAGCATTATAAATTACAGCGTGATTTGGAAATTGTCGTA
ATGGACGCTGAGCGCGCATTGGGAAATGGTTTTGTATTGCCTGCAGGCCCATTGCGTGAATTACCAAGTCGATTAAAATC
CGTAGATTTTGTGATCACTAATGGTGGAAAAAATCAGTATTCAGATGCAGTTATGTATCTTGTACCCCATTTCGCAATTA
ATTTAAAAACCAATGAAAAACGCCAATTAAAGGAATTTCAATCTGGTGTTGCCATTGCAGGGATTGGCAATCCACAGCGT
TTTTTTACTATGTTAGAAAAGTTAGGGATTCAATTAGAACGAACTCAAGCATTTCAAGATCATCAACATTTTGAAGCCTC
TCAATTAGAAAAACTTGCTGAAAATCAACCGCTCTTTATGACGGAAAAAGATGCCGTAAAATGCCAATCTTTTGCTAAAG
ATAATTGGTGGTATGTCCCTGTGGATGCAGAGATTATTGAGGCTGAAAAACAATGTGAAAATTTACCGCACTTTTGGGGC
AAAATAGACAAACTTGTGGCGCAATATAGAAATGGCTGA

Upstream 100 bases:

>100_bases
GCTATACAGTATGCAGTTTAGTGGCTAATTTATTAATTATTGAAAACGCGAGTTGAAAAACTCGCGTTATTTTATCCGCA
CTTATTAGAAAGGATTTTCT

Downstream 100 bases:

>100_bases
AAGGATTTATCTCCAGTTGTTTTGATTGCTTGCCGATAAAGCTGAAATATTAAAGAATAAGGAATAAATTATGTCATTTA
CCGTTATTATCCCCGCTCGT

Product: tetraacyldisaccharide 4'-kinase

Products: NA

Alternate protein names: Lipid A 4'-kinase [H]

Number of amino acids: Translated: 332; Mature: 331

Protein sequence:

>332_residues
MPFWYSNSKLIWLLSPFSLLFWLISQLRHALFCLGIKSSYRAPKPVIIVGNLSVGGNGKTPVVVWLVEELKKRGLRVGVI
SRGYGSKSKTYPLFVTENTRPIEGGDEPVLIAKRTNAPVVISPNRQQAIELLLSQAECDIIVSDDGLQHYKLQRDLEIVV
MDAERALGNGFVLPAGPLRELPSRLKSVDFVITNGGKNQYSDAVMYLVPHFAINLKTNEKRQLKEFQSGVAIAGIGNPQR
FFTMLEKLGIQLERTQAFQDHQHFEASQLEKLAENQPLFMTEKDAVKCQSFAKDNWWYVPVDAEIIEAEKQCENLPHFWG
KIDKLVAQYRNG

Sequences:

>Translated_332_residues
MPFWYSNSKLIWLLSPFSLLFWLISQLRHALFCLGIKSSYRAPKPVIIVGNLSVGGNGKTPVVVWLVEELKKRGLRVGVI
SRGYGSKSKTYPLFVTENTRPIEGGDEPVLIAKRTNAPVVISPNRQQAIELLLSQAECDIIVSDDGLQHYKLQRDLEIVV
MDAERALGNGFVLPAGPLRELPSRLKSVDFVITNGGKNQYSDAVMYLVPHFAINLKTNEKRQLKEFQSGVAIAGIGNPQR
FFTMLEKLGIQLERTQAFQDHQHFEASQLEKLAENQPLFMTEKDAVKCQSFAKDNWWYVPVDAEIIEAEKQCENLPHFWG
KIDKLVAQYRNG
>Mature_331_residues
PFWYSNSKLIWLLSPFSLLFWLISQLRHALFCLGIKSSYRAPKPVIIVGNLSVGGNGKTPVVVWLVEELKKRGLRVGVIS
RGYGSKSKTYPLFVTENTRPIEGGDEPVLIAKRTNAPVVISPNRQQAIELLLSQAECDIIVSDDGLQHYKLQRDLEIVVM
DAERALGNGFVLPAGPLRELPSRLKSVDFVITNGGKNQYSDAVMYLVPHFAINLKTNEKRQLKEFQSGVAIAGIGNPQRF
FTMLEKLGIQLERTQAFQDHQHFEASQLEKLAENQPLFMTEKDAVKCQSFAKDNWWYVPVDAEIIEAEKQCENLPHFWGK
IDKLVAQYRNG

Specific function: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) [H]

COG id: COG1663

COG function: function code M; Tetraacyldisaccharide-1-P 4'-kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lpxK family [H]

Homologues:

Organism=Escherichia coli, GI1787144, Length=305, Percent_Identity=51.1475409836066, Blast_Score=323, Evalue=7e-90,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003758 [H]

Pfam domain/function: PF02606 LpxK [H]

EC number: =2.7.1.130 [H]

Molecular weight: Translated: 37527; Mature: 37396

Theoretical pI: Translated: 8.82; Mature: 8.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPFWYSNSKLIWLLSPFSLLFWLISQLRHALFCLGIKSSYRAPKPVIIVGNLSVGGNGKT
CCEEECCCEEEEEECHHHHHHHHHHHHHHHHEEEECCCCCCCCCCEEEEEEEEECCCCCC
PVVVWLVEELKKRGLRVGVISRGYGSKSKTYPLFVTENTRPIEGGDEPVLIAKRTNAPVV
CEEEEEHHHHHHCCCEEEEEECCCCCCCCEEEEEEECCCCCCCCCCCCEEEEECCCCCEE
ISPNRQQAIELLLSQAECDIIVSDDGLQHYKLQRDLEIVVMDAERALGNGFVLPAGPLRE
ECCCHHHHHHHHHHHCCCEEEECCCCCHHHEECCCEEEEEEECHHHCCCCEEECCCHHHH
LPSRLKSVDFVITNGGKNQYSDAVMYLVPHFAINLKTNEKRQLKEFQSGVAIAGIGNPQR
HHHHHHHEEEEEECCCCCCHHHHHHEEECEEEEEECCCCHHHHHHHHCCEEEEECCCHHH
FFTMLEKLGIQLERTQAFQDHQHFEASQLEKLAENQPLFMTEKDAVKCQSFAKDNWWYVP
HHHHHHHHCCEEEEHHHHHHHHCCCHHHHHHHHCCCCEEEECHHHHHHHHHCCCCCEEEE
VDAEIIEAEKQCENLPHFWGKIDKLVAQYRNG
CCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
PFWYSNSKLIWLLSPFSLLFWLISQLRHALFCLGIKSSYRAPKPVIIVGNLSVGGNGKT
CEEECCCEEEEEECHHHHHHHHHHHHHHHHEEEECCCCCCCCCCEEEEEEEEECCCCCC
PVVVWLVEELKKRGLRVGVISRGYGSKSKTYPLFVTENTRPIEGGDEPVLIAKRTNAPVV
CEEEEEHHHHHHCCCEEEEEECCCCCCCCEEEEEEECCCCCCCCCCCCEEEEECCCCCEE
ISPNRQQAIELLLSQAECDIIVSDDGLQHYKLQRDLEIVVMDAERALGNGFVLPAGPLRE
ECCCHHHHHHHHHHHCCCEEEECCCCCHHHEECCCEEEEEEECHHHCCCCEEECCCHHHH
LPSRLKSVDFVITNGGKNQYSDAVMYLVPHFAINLKTNEKRQLKEFQSGVAIAGIGNPQR
HHHHHHHEEEEEECCCCCCHHHHHHEEECEEEEEECCCCHHHHHHHHCCEEEEECCCHHH
FFTMLEKLGIQLERTQAFQDHQHFEASQLEKLAENQPLFMTEKDAVKCQSFAKDNWWYVP
HHHHHHHHCCEEEEHHHHHHHHCCCHHHHHHHHCCCCEEEECHHHHHHHHHCCCCCEEEE
VDAEIIEAEKQCENLPHFWGKIDKLVAQYRNG
CCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA