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The map label for this gene is fabD [H]

Identifier: 148825576

GI number: 148825576

Start: 492625

End: 493563

Strand: Direct

Name: fabD [H]

Synonym: CGSHiEE_02505

Alternate gene names: 148825576

Gene position: 492625-493563 (Clockwise)

Preceding gene: 148825575

Following gene: 148825577

Centisome position: 27.17

GC content: 42.39

Gene sequence:

>939_bases
ATGAAAAAATTCGCAATGGTCTTCCCAGGTCAAGGCTCCCAAGCTGTCGGTATGCTTGCTGATCTTGCCACTGAATATCC
AATCGTTATTGAAACATTTAAACAAGCATCTGATGCACTTGGTTATGATTTATGGTATCTTGTTCAACAGGGTCCAGCTG
AAGAACTTAATAAAACTTGGCAAACTCAGCCCGCACTTTTGGCTGCTTCAGTCGCTATTTATCGCGTATGGCAAGAAAAA
TTTCCTCAATTAAAACCAGAAGTGATGGCAGGCCATAGCTTGGGTGAGTATTCTGCCTTGGTTTGTGCTGGGGTGTTGGA
TTTCCAAGATGCGATTAAATTAGTGGAATTGCGCGGAAAATTAATGCAACAAGCTGTGCCTGAAGGCACTGGCGCAATGT
ATGCAATCATTGGTTTAGATAATGAAGCAATTATTAATGCTTGCAAACAAGCAGAGGAAGGCGAAGTCGTATCTGCGGTG
AACTTTAACTCACCGGGTCAAGTAGTTATTGCGGGTGCGAAAGCTGCAGTTGAGCGTGCGGCTGCATTATGTAAAGAATC
AGGGGCGAAACGTGCATTGCTGTTAGCTGTGAGCGTACCTTCTCACTGTGCATTAATGAAACCTGCAGCCGAGCAATTAG
CGGTAACACTTGAGAATATTCAAATTAATACACCAACAACATCGGTATTAAATAACGTTGATGTGAAAGCTGAAACCGAA
GGCACCGAAATTCGTACCGCACTTGTTCGTCAGTTATATAGTCCAGTTCGTTGGACTGAAACAGTTGAAAAAATGGCGCA
AGATGGTGTTTTAGCGCTTGTTGAAGTGGGGCCAGGTAAAGTATTAAATGGTTTAACCAAACGCATTGTGGGTGATTTAC
AAGCAATATCTGTAAATGATGTTGCATCATTCAATGCGGTAGAAGAATTTTTAGCGTAA

Upstream 100 bases:

>100_bases
TTCTTTGGCGAAGCAAAGAAAAAGTAAGTCGCCATCGGCGAAACCCGATTTTAATTACCGAAGAAGAATTTTCAATTAAA
AAACAATAGGACAAAACATA

Downstream 100 bases:

>100_bases
GTAAAAGGAAGAAAAAATGCAAGGTAAAATTGCTTTAGTGACAGGGGCTACCCGTGGTATCGGTCGTGCGATTGCAGAAG
AACTTAGTTCAAAAGGTGCA

Product: acyl carrier protein S-malonyltransferase

Products: NA

Alternate protein names: MCT [H]

Number of amino acids: Translated: 312; Mature: 312

Protein sequence:

>312_residues
MKKFAMVFPGQGSQAVGMLADLATEYPIVIETFKQASDALGYDLWYLVQQGPAEELNKTWQTQPALLAASVAIYRVWQEK
FPQLKPEVMAGHSLGEYSALVCAGVLDFQDAIKLVELRGKLMQQAVPEGTGAMYAIIGLDNEAIINACKQAEEGEVVSAV
NFNSPGQVVIAGAKAAVERAAALCKESGAKRALLLAVSVPSHCALMKPAAEQLAVTLENIQINTPTTSVLNNVDVKAETE
GTEIRTALVRQLYSPVRWTETVEKMAQDGVLALVEVGPGKVLNGLTKRIVGDLQAISVNDVASFNAVEEFLA

Sequences:

>Translated_312_residues
MKKFAMVFPGQGSQAVGMLADLATEYPIVIETFKQASDALGYDLWYLVQQGPAEELNKTWQTQPALLAASVAIYRVWQEK
FPQLKPEVMAGHSLGEYSALVCAGVLDFQDAIKLVELRGKLMQQAVPEGTGAMYAIIGLDNEAIINACKQAEEGEVVSAV
NFNSPGQVVIAGAKAAVERAAALCKESGAKRALLLAVSVPSHCALMKPAAEQLAVTLENIQINTPTTSVLNNVDVKAETE
GTEIRTALVRQLYSPVRWTETVEKMAQDGVLALVEVGPGKVLNGLTKRIVGDLQAISVNDVASFNAVEEFLA
>Mature_312_residues
MKKFAMVFPGQGSQAVGMLADLATEYPIVIETFKQASDALGYDLWYLVQQGPAEELNKTWQTQPALLAASVAIYRVWQEK
FPQLKPEVMAGHSLGEYSALVCAGVLDFQDAIKLVELRGKLMQQAVPEGTGAMYAIIGLDNEAIINACKQAEEGEVVSAV
NFNSPGQVVIAGAKAAVERAAALCKESGAKRALLLAVSVPSHCALMKPAAEQLAVTLENIQINTPTTSVLNNVDVKAETE
GTEIRTALVRQLYSPVRWTETVEKMAQDGVLALVEVGPGKVLNGLTKRIVGDLQAISVNDVASFNAVEEFLA

Specific function: Fatty acid biosynthesis. [C]

COG id: COG0331

COG function: function code I; (acyl-carrier-protein) S-malonyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabD family [H]

Homologues:

Organism=Homo sapiens, GI51243059, Length=300, Percent_Identity=34.3333333333333, Blast_Score=150, Evalue=1e-36,
Organism=Homo sapiens, GI27477045, Length=111, Percent_Identity=44.1441441441441, Blast_Score=82, Evalue=9e-16,
Organism=Escherichia coli, GI1787334, Length=310, Percent_Identity=70.3225806451613, Blast_Score=413, Evalue=1e-117,
Organism=Caenorhabditis elegans, GI71984332, Length=292, Percent_Identity=31.1643835616438, Blast_Score=129, Evalue=3e-30,
Organism=Caenorhabditis elegans, GI17550940, Length=296, Percent_Identity=28.3783783783784, Blast_Score=91, Evalue=7e-19,
Organism=Drosophila melanogaster, GI24665753, Length=311, Percent_Identity=32.7974276527331, Blast_Score=141, Evalue=6e-34,

Paralogues:

None

Copy number: 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR004410
- InterPro:   IPR016036 [H]

Pfam domain/function: PF00698 Acyl_transf_1 [H]

EC number: =2.3.1.39 [H]

Molecular weight: Translated: 33387; Mature: 33387

Theoretical pI: Translated: 4.58; Mature: 4.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKFAMVFPGQGSQAVGMLADLATEYPIVIETFKQASDALGYDLWYLVQQGPAEELNKTW
CCCEEEEECCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHCHHHHHHCCCCCHHHHHHHH
QTQPALLAASVAIYRVWQEKFPQLKPEVMAGHSLGEYSALVCAGVLDFQDAIKLVELRGK
CCCHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LMQQAVPEGTGAMYAIIGLDNEAIINACKQAEEGEVVSAVNFNSPGQVVIAGAKAAVERA
HHHHHCCCCCCCEEEEEECCCHHHHHHHHCCCCCCEEEEEECCCCCCEEEECHHHHHHHH
AALCKESGAKRALLLAVSVPSHCALMKPAAEQLAVTLENIQINTPTTSVLNNVDVKAETE
HHHHHHCCCCEEEEEEEECCCCHHHHCHHHHHHHEEHHHEEECCCHHHHHCCCCCEECCC
GTEIRTALVRQLYSPVRWTETVEKMAQDGVLALVEVGPGKVLNGLTKRIVGDLQAISVND
CHHHHHHHHHHHHCCHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHEEEHHH
VASFNAVEEFLA
HHHHHHHHHHHC
>Mature Secondary Structure
MKKFAMVFPGQGSQAVGMLADLATEYPIVIETFKQASDALGYDLWYLVQQGPAEELNKTW
CCCEEEEECCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHCHHHHHHCCCCCHHHHHHHH
QTQPALLAASVAIYRVWQEKFPQLKPEVMAGHSLGEYSALVCAGVLDFQDAIKLVELRGK
CCCHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LMQQAVPEGTGAMYAIIGLDNEAIINACKQAEEGEVVSAVNFNSPGQVVIAGAKAAVERA
HHHHHCCCCCCCEEEEEECCCHHHHHHHHCCCCCCEEEEEECCCCCCEEEECHHHHHHHH
AALCKESGAKRALLLAVSVPSHCALMKPAAEQLAVTLENIQINTPTTSVLNNVDVKAETE
HHHHHHCCCCEEEEEEEECCCCHHHHCHHHHHHHEEHHHEEECCCHHHHHCCCCCEECCC
GTEIRTALVRQLYSPVRWTETVEKMAQDGVLALVEVGPGKVLNGLTKRIVGDLQAISVND
CHHHHHHHHHHHHCCHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHEEEHHH
VASFNAVEEFLA
HHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]