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The map label for this gene is ybfF [C]

Identifier: 148825542

GI number: 148825542

Start: 452043

End: 452825

Strand: Direct

Name: ybfF [C]

Synonym: CGSHiEE_02295

Alternate gene names: 148825542

Gene position: 452043-452825 (Clockwise)

Preceding gene: 148825535

Following gene: 148825543

Centisome position: 24.93

GC content: 33.08

Gene sequence:

>783_bases
ATGGCAAAATCATTACTCAATTATCAATTTCATCAAGTAAAACAAACGATTAATACACCTGTTTTAATTTTTATTCACGG
TTTATTCGGCGATATGGATAATCTCGGCGTTATTGCGAGAGCTTTTAGTGAACATTACAGTATTTTACGTATTGATTTAC
GCAATCATGGCCATAGTTTTCATTCGGAAAAAATGAATTATCAACTGATGGCTGAAGATGTTATCGCAGTAATCCGCCAC
TTAAATTTATCCAAAGTGATATTAATTGGTCATTCTATGGGGGGAAAAACCGCCATGAAAATCACCGCACTTTGCCCAGA
ATTAGTCGAAAAATTAATCGTAATTGATATGTCTCCTATGCCTTATGAGGGATTTGGTCATAAAGATGTTTTTAATGGCC
TATTTGCGGTAAAAAATGCAAAGCCTGAAAATCGTCAGCAAGCCAAACCGATTTTAAAACAAGAAATTAATGATGAAGAC
GTTGTACAATTTATGTTGAAATCTTTTGATGTTAATTCAGCTGATTGTTTTCGTTTTAATCTTACCGCACTTTTTAACAA
TTATGCCAATATTATGGATTGGGAAAAAGTACGTGTATTTACGCCAACTCTTTTTATTAAGGGTGGAAATTCCTCTTATA
TAAAAATAGAAAATAGCGAAAAAATTCTAGAACAATTTCCTAATGCAACTGCCTTTACGATTAATGGCAGTGGACACTGG
GTTCACGCCGAAAAACCTGATTTTGTTATTCGTGCAATTAAACGATTTCTAAATAAGAATTAA

Upstream 100 bases:

>100_bases
TAATTCTTCATCTACTTCAATGATCTTCATTTTTATCTCTCTGTTTGCTAAAATTTTTTTCAATTATAACGACTTCTTTA
CAAATTCTCACGTAAAAATT

Downstream 100 bases:

>100_bases
GTAGTTTAAGTGAGAATGCTTTTATGATATAGTTCGCTAAATTTGGATAAGCCTTATAATCGATAGATTAAATTTAATAT
AAAAAAGGAAATAAAAATGG

Product: esterase/lipase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 260; Mature: 259

Protein sequence:

>260_residues
MAKSLLNYQFHQVKQTINTPVLIFIHGLFGDMDNLGVIARAFSEHYSILRIDLRNHGHSFHSEKMNYQLMAEDVIAVIRH
LNLSKVILIGHSMGGKTAMKITALCPELVEKLIVIDMSPMPYEGFGHKDVFNGLFAVKNAKPENRQQAKPILKQEINDED
VVQFMLKSFDVNSADCFRFNLTALFNNYANIMDWEKVRVFTPTLFIKGGNSSYIKIENSEKILEQFPNATAFTINGSGHW
VHAEKPDFVIRAIKRFLNKN

Sequences:

>Translated_260_residues
MAKSLLNYQFHQVKQTINTPVLIFIHGLFGDMDNLGVIARAFSEHYSILRIDLRNHGHSFHSEKMNYQLMAEDVIAVIRH
LNLSKVILIGHSMGGKTAMKITALCPELVEKLIVIDMSPMPYEGFGHKDVFNGLFAVKNAKPENRQQAKPILKQEINDED
VVQFMLKSFDVNSADCFRFNLTALFNNYANIMDWEKVRVFTPTLFIKGGNSSYIKIENSEKILEQFPNATAFTINGSGHW
VHAEKPDFVIRAIKRFLNKN
>Mature_259_residues
AKSLLNYQFHQVKQTINTPVLIFIHGLFGDMDNLGVIARAFSEHYSILRIDLRNHGHSFHSEKMNYQLMAEDVIAVIRHL
NLSKVILIGHSMGGKTAMKITALCPELVEKLIVIDMSPMPYEGFGHKDVFNGLFAVKNAKPENRQQAKPILKQEINDEDV
VQFMLKSFDVNSADCFRFNLTALFNNYANIMDWEKVRVFTPTLFIKGGNSSYIKIENSEKILEQFPNATAFTINGSGHWV
HAEKPDFVIRAIKRFLNKN

Specific function: Unknown

COG id: COG0596

COG function: function code R; Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dmpD/todF/xylF esterase family

Homologues:

Organism=Homo sapiens, GI23200008, Length=248, Percent_Identity=35.0806451612903, Blast_Score=157, Evalue=7e-39,
Organism=Homo sapiens, GI23200012, Length=248, Percent_Identity=35.0806451612903, Blast_Score=157, Evalue=7e-39,
Organism=Homo sapiens, GI223941839, Length=243, Percent_Identity=29.6296296296296, Blast_Score=115, Evalue=5e-26,
Organism=Escherichia coli, GI1786902, Length=254, Percent_Identity=43.3070866141732, Blast_Score=232, Evalue=2e-62,
Organism=Caenorhabditis elegans, GI17508535, Length=255, Percent_Identity=32.9411764705882, Blast_Score=119, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI17507063, Length=270, Percent_Identity=27.7777777777778, Blast_Score=88, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17554012, Length=274, Percent_Identity=26.6423357664234, Blast_Score=78, Evalue=5e-15,
Organism=Saccharomyces cerevisiae, GI6321468, Length=269, Percent_Identity=30.8550185873606, Blast_Score=91, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24640348, Length=261, Percent_Identity=32.5670498084291, Blast_Score=114, Evalue=5e-26,
Organism=Drosophila melanogaster, GI24646055, Length=261, Percent_Identity=22.6053639846743, Blast_Score=82, Evalue=4e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y193_HAEIN (Q57427)

Other databases:

- EMBL:   L42023
- PIR:   E64053
- RefSeq:   NP_438361.2
- ProteinModelPortal:   Q57427
- SMR:   Q57427
- GeneID:   951100
- GenomeReviews:   L42023_GR
- KEGG:   hin:HI0193
- NMPDR:   fig|71421.1.peg.182
- TIGR:   HI_0193
- HOGENOM:   HBG748003
- OMA:   GGKTAMK
- ProtClustDB:   CLSK870065
- BioCyc:   HINF71421:HI_0193-MONOMER
- InterPro:   IPR000073
- InterPro:   IPR012908
- PRINTS:   PR00111

Pfam domain/function: PF00561 Abhydrolase_1; PF07819 PGAP1

EC number: 3.1.-.- [C]

Molecular weight: Translated: 29688; Mature: 29557

Theoretical pI: Translated: 9.01; Mature: 9.01

Prosite motif: PS00120 LIPASE_SER

Important sites: ACT_SITE 119-119 ACT_SITE 266-266

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKSLLNYQFHQVKQTINTPVLIFIHGLFGDMDNLGVIARAFSEHYSILRIDLRNHGHSF
CCCHHHHHHHHHHHHHHCCCEEEEEEHHHCCCCCHHHHHHHHHHCCEEEEEEECCCCCCH
HSEKMNYQLMAEDVIAVIRHLNLSKVILIGHSMGGKTAMKITALCPELVEKLIVIDMSPM
HHHCCCHHHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHEECCCCC
PYEGFGHKDVFNGLFAVKNAKPENRQQAKPILKQEINDEDVVQFMLKSFDVNSADCFRFN
CCCCCCCHHHHHHHHEECCCCCCCHHHHCCHHHHHCCHHHHHHHHHHHCCCCCCCEEEEE
LTALFNNYANIMDWEKVRVFTPTLFIKGGNSSYIKIENSEKILEQFPNATAFTINGSGHW
HHHHHHHHHHHCCCCEEEEEEEEEEEECCCCCEEEECCHHHHHHHCCCCEEEEECCCCEE
VHAEKPDFVIRAIKRFLNKN
EECCCCHHHHHHHHHHHCCC
>Mature Secondary Structure 
AKSLLNYQFHQVKQTINTPVLIFIHGLFGDMDNLGVIARAFSEHYSILRIDLRNHGHSF
CCHHHHHHHHHHHHHHCCCEEEEEEHHHCCCCCHHHHHHHHHHCCEEEEEEECCCCCCH
HSEKMNYQLMAEDVIAVIRHLNLSKVILIGHSMGGKTAMKITALCPELVEKLIVIDMSPM
HHHCCCHHHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHEECCCCC
PYEGFGHKDVFNGLFAVKNAKPENRQQAKPILKQEINDEDVVQFMLKSFDVNSADCFRFN
CCCCCCCHHHHHHHHEECCCCCCCHHHHCCHHHHHCCHHHHHHHHHHHCCCCCCCEEEEE
LTALFNNYANIMDWEKVRVFTPTLFIKGGNSSYIKIENSEKILEQFPNATAFTINGSGHW
HHHHHHHHHHHCCCCEEEEEEEEEEEECCCCCEEEECCHHHHHHHCCCCEEEEECCCCEE
VHAEKPDFVIRAIKRFLNKN
EECCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800