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The map label for this gene is tolA [H]

Identifier: 148825335

GI number: 148825335

Start: 208189

End: 209367

Strand: Direct

Name: tolA [H]

Synonym: CGSHiEE_01085

Alternate gene names: 148825335

Gene position: 208189-209367 (Clockwise)

Preceding gene: 148825334

Following gene: 148825336

Centisome position: 11.48

GC content: 42.58

Gene sequence:

>1179_bases
GTGCAAAATAATCGACAAAAGAAAGGAATCAATGCTTTTGCTATTTCTATCCTTTTGCACTTTATCTTGTTTGGCTTATT
GATTTTAAGTTCACTTTATCACACTGTTGAAATTATGGGTGGTGGAGAAGGTGAAGGAGATGTAATAGGGGCAGTGATTG
TTGATACGGGTACGGCTGCTCAGGAATGGGGGCGTATTCAACAACAAAAAAAAGGGCAAGCGGATAAACAAAAACGCCCA
GAACCTGTTGTGGAAGAAAAACCACCTGAGCCTAATCAAGAAGAGATTAAGCATCAACAAGAAGTTCAACGACAAGAAGA
GTTAAAACGTCAGCAAGAACAGCAACGTCAGCAAGAACAGCAACGTCAGCAAGAACAGCAACGTCAGCAAGAACAACAAC
GTCAGCAAGAAATAAAAAAACAACAAGAGCAAGCTCGTCAAGAAGCGTTGGAAAAACAGAAGCAAGCTGAAGAGGCTAAG
GCTAAACAAGCGGCTGAAGCTGCAAAATTAAAAGCAGATGCAGAGGCTAAACGTTTAGCTGCTGCGGCAAAACAAGCTGA
AGAAGAGGCTAAAGCGAAAGCCGCAGAAATTGCTGCTCAAAAAGCAAAACAAGAGGCGGAAGCTAAGGCAAAACTAGAAG
CGGAAGCTAAGGCAAAAGCCGCCGCTGAAGCTAAAGCAAAGGCTGAAGCGGAGGCAAAAGCAAAAGCTGATGCAGAAGCT
AAAGCGAAAGCCGCTGCTGAGGCAAAAGCTAAAGCTGCTACGGAAGCGAAACGTAAAGCAGATCAAGCAAGCCTAGATGA
TTTCTTAAATGGCGGAGATATTGGTGGCGGCAGTGCATCTAAAGGGGGAAACACAAATAAAGGTGGAACTCAAGGTAGCG
GTGCTGCACTTGGCTCTGGCGATGGTGGTAAGGTTGGGGATCAATACGCAGGTGTAATTAAGAAAGAGATTCAACGTCGT
TTCTTAAAAGATCCAAATTTTGCAGGAAAGGTTTGTCGTATTAAAATTCAATTAGGTCGAGATGGCACAATCTTGGGGTA
TCAAAAAATTTCAGGCTCTGATGATATTTGTTCAGCTGCATTAAGTGCGGTGGCTAGAACGAAAAAAGTTCCAGCTGCGC
CATCAGATGAAATTTATGAAAAATATAAATCACCAATTATTGACTTTGATATTCGATAA

Upstream 100 bases:

>100_bases
GCCTTATGAAGAAGTGATTAAGGCATTGAATTTACTTCATCTTGCAGGCATTAAATCTGTAGGTTTAATGACAAATCCCA
TTTAGCTAAGTAGGTAACAC

Downstream 100 bases:

>100_bases
TTCTTTAGAAAAATTTATTGTTAAATTTTAAAGGTAACAAAATGAAATTATTAAAACGTTTAGTGAGCGTATTTGCGATT
GTACTTGCTGTTGGAAGCAA

Product: cell envelope integrity inner membrane protein TolA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 392; Mature: 392

Protein sequence:

>392_residues
MQNNRQKKGINAFAISILLHFILFGLLILSSLYHTVEIMGGGEGEGDVIGAVIVDTGTAAQEWGRIQQQKKGQADKQKRP
EPVVEEKPPEPNQEEIKHQQEVQRQEELKRQQEQQRQQEQQRQQEQQRQQEQQRQQEIKKQQEQARQEALEKQKQAEEAK
AKQAAEAAKLKADAEAKRLAAAAKQAEEEAKAKAAEIAAQKAKQEAEAKAKLEAEAKAKAAAEAKAKAEAEAKAKADAEA
KAKAAAEAKAKAATEAKRKADQASLDDFLNGGDIGGGSASKGGNTNKGGTQGSGAALGSGDGGKVGDQYAGVIKKEIQRR
FLKDPNFAGKVCRIKIQLGRDGTILGYQKISGSDDICSAALSAVARTKKVPAAPSDEIYEKYKSPIIDFDIR

Sequences:

>Translated_392_residues
MQNNRQKKGINAFAISILLHFILFGLLILSSLYHTVEIMGGGEGEGDVIGAVIVDTGTAAQEWGRIQQQKKGQADKQKRP
EPVVEEKPPEPNQEEIKHQQEVQRQEELKRQQEQQRQQEQQRQQEQQRQQEQQRQQEIKKQQEQARQEALEKQKQAEEAK
AKQAAEAAKLKADAEAKRLAAAAKQAEEEAKAKAAEIAAQKAKQEAEAKAKLEAEAKAKAAAEAKAKAEAEAKAKADAEA
KAKAAAEAKAKAATEAKRKADQASLDDFLNGGDIGGGSASKGGNTNKGGTQGSGAALGSGDGGKVGDQYAGVIKKEIQRR
FLKDPNFAGKVCRIKIQLGRDGTILGYQKISGSDDICSAALSAVARTKKVPAAPSDEIYEKYKSPIIDFDIR
>Mature_392_residues
MQNNRQKKGINAFAISILLHFILFGLLILSSLYHTVEIMGGGEGEGDVIGAVIVDTGTAAQEWGRIQQQKKGQADKQKRP
EPVVEEKPPEPNQEEIKHQQEVQRQEELKRQQEQQRQQEQQRQQEQQRQQEQQRQQEIKKQQEQARQEALEKQKQAEEAK
AKQAAEAAKLKADAEAKRLAAAAKQAEEEAKAKAAEIAAQKAKQEAEAKAKLEAEAKAKAAAEAKAKAEAEAKAKADAEA
KAKAAAEAKAKAATEAKRKADQASLDDFLNGGDIGGGSASKGGNTNKGGTQGSGAALGSGDGGKVGDQYAGVIKKEIQRR
FLKDPNFAGKVCRIKIQLGRDGTILGYQKISGSDDICSAALSAVARTKKVPAAPSDEIYEKYKSPIIDFDIR

Specific function: Involved in the tonB-independent uptake of proteins [H]

COG id: COG3064

COG function: function code M; Membrane protein involved in colicin uptake

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014161 [H]

Pfam domain/function: PF06519 TolA [H]

EC number: NA

Molecular weight: Translated: 42396; Mature: 42396

Theoretical pI: Translated: 9.71; Mature: 9.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHCCCCCCCHHHHHHHCCCCCCCCCC
>Mature Secondary Structure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HHHHHHHHCCCCCCCHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800; 8921895 [H]