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The map label for this gene is tolR [H]

Identifier: 148825334

GI number: 148825334

Start: 207754

End: 208173

Strand: Direct

Name: tolR [H]

Synonym: CGSHiEE_01080

Alternate gene names: 148825334

Gene position: 207754-208173 (Clockwise)

Preceding gene: 148825333

Following gene: 148825335

Centisome position: 11.46

GC content: 35.95

Gene sequence:

>420_bases
ATGGCTCGTCGTCAGCGTAAAGCAATTAAATCTGAAATTAATATTGTGCCTTTTTTGGATGTGCTTTTAGTTTTAGTGTT
AATTTTTATGGCAACCGCCCCTATTATTAGTCAAAGCGTTCAAGTTGAATTGCCTGATTCTGTGCAAAGCCAAGAGGTTT
CTAATGAAGATAAAGTCCCCGTCATTCTTGAAGTGGCAGGCATTGGAAAATATGCGATTTCTATTGGCGGAGAACGTCAA
GAAGGTTTAACAGAAGAAATGGTTACTCAATTATCTAGACAGGAATTTGATAAGAATAATAATACACTATTTTTAGTAGG
CGGAGCTAAAGAAGTGCCTTATGAAGAAGTGATTAAGGCATTGAATTTACTTCATCTTGCAGGCATTAAATCTGTAGGTT
TAATGACAAATCCCATTTAG

Upstream 100 bases:

>100_bases
CGTCAAGCCTTTGGTAAAGCCCCTCACTAAAAATAGGGAAAATTGACCGCACTTTGAAGAAAAAGTGCGGTAAAAATAAG
TTAAAATTTTAGAGGAATAT

Downstream 100 bases:

>100_bases
CTAAGTAGGTAACACGTGCAAAATAATCGACAAAAGAAAGGAATCAATGCTTTTGCTATTTCTATCCTTTTGCACTTTAT
CTTGTTTGGCTTATTGATTT

Product: colicin uptake protein TolR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 139; Mature: 138

Protein sequence:

>139_residues
MARRQRKAIKSEINIVPFLDVLLVLVLIFMATAPIISQSVQVELPDSVQSQEVSNEDKVPVILEVAGIGKYAISIGGERQ
EGLTEEMVTQLSRQEFDKNNNTLFLVGGAKEVPYEEVIKALNLLHLAGIKSVGLMTNPI

Sequences:

>Translated_139_residues
MARRQRKAIKSEINIVPFLDVLLVLVLIFMATAPIISQSVQVELPDSVQSQEVSNEDKVPVILEVAGIGKYAISIGGERQ
EGLTEEMVTQLSRQEFDKNNNTLFLVGGAKEVPYEEVIKALNLLHLAGIKSVGLMTNPI
>Mature_138_residues
ARRQRKAIKSEINIVPFLDVLLVLVLIFMATAPIISQSVQVELPDSVQSQEVSNEDKVPVILEVAGIGKYAISIGGERQE
GLTEEMVTQLSRQEFDKNNNTLFLVGGAKEVPYEEVIKALNLLHLAGIKSVGLMTNPI

Specific function: Involved in the tonB-independent uptake of proteins [H]

COG id: COG0848

COG function: function code U; Biopolymer transport protein

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the exbD/tolR family [H]

Homologues:

Organism=Escherichia coli, GI1786959, Length=131, Percent_Identity=63.3587786259542, Blast_Score=144, Evalue=2e-36,
Organism=Escherichia coli, GI1789380, Length=123, Percent_Identity=35.7723577235772, Blast_Score=67, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003400 [H]

Pfam domain/function: PF02472 ExbD [H]

EC number: NA

Molecular weight: Translated: 15257; Mature: 15126

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARRQRKAIKSEINIVPFLDVLLVLVLIFMATAPIISQSVQVELPDSVQSQEVSNEDKVP
CCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCHHHHCCCCCCCC
VILEVAGIGKYAISIGGERQEGLTEEMVTQLSRQEFDKNNNTLFLVGGAKEVPYEEVIKA
EEEEECCCCEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHH
LNLLHLAGIKSVGLMTNPI
HHHHHHHCHHHCCCCCCCC
>Mature Secondary Structure 
ARRQRKAIKSEINIVPFLDVLLVLVLIFMATAPIISQSVQVELPDSVQSQEVSNEDKVP
CHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCHHHHCCCCCCCC
VILEVAGIGKYAISIGGERQEGLTEEMVTQLSRQEFDKNNNTLFLVGGAKEVPYEEVIKA
EEEEECCCCEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHH
LNLLHLAGIKSVGLMTNPI
HHHHHHHCHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800; 8921895 [H]