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The map label for this gene is glmS [H]

Identifier: 148825291

GI number: 148825291

Start: 160822

End: 162654

Strand: Direct

Name: glmS [H]

Synonym: CGSHiEE_00845

Alternate gene names: 148825291

Gene position: 160822-162654 (Clockwise)

Preceding gene: 148825290

Following gene: 148825293

Centisome position: 8.87

GC content: 39.23

Gene sequence:

>1833_bases
ATGTGTGGTATTGTCGGTGCAGTAGCGCAACGAGATGTAGCGGAAATCTTAATTAATGGTTTACATCGTTTAGAATATCG
TGGTTATGATTCAGCTGGTGTTGCAGTAATCAATAAACAAAATGAATTACAACGTATTCGTTGTTTAGGCAAAGTTAAAG
CTTTAGATGAAGCCGTATCAGAAAAACCATTAATTGGTGGAACGGGAATTGCACATACTCGCTGGGCAACTCACGGCGAA
CCATCAGAAACTAATGCGCATCCGCATTCATCAGGTACTTTTGCTGTAGTACATAACGGTATTATTGAAAATCACGAAGA
ACTTCGCGAATTATTAAAATCTCGTGGTTATGTCTTTTTATCACAAACAGATACTGAAGTGATCGCTCACCTCGTTGAAT
GGGAAATGCGTAGCACGGATTCCCTTTTAGAGGCTGTGCAGAAATCGGTAAAACAACTCACGGGCGCATATGGTATGGTG
GTAATGGACAGCCGTCATCCTGAACATTTAGTGGCAGCTCGTTCTGGTAGTCCACTTGTGATTGGCTTAGGTATCGGTGA
AAATTTCTTAGCTTCAGATCAACTTGCGCTTTTAAGTGTTACTCGCCGTTTTATCTTTTTAGAAGAAGGAGATATTGCAG
AAATTACACGTCGTACAGTTGATATTTATGATACTCACGGTAATAAGGCTAAACGTGAAATTCACGAGTCTAATCTTGAA
AATGACGCTGCAGAGAAAGGTAAATTCCGTCATTTTATGCAGAAAGAAATTTACGAACAGCCAACTGCACTTATTAATAC
AATGGAAGGGCGTATTAATCACGAAAATGTGATTGTTGATTCAATCGGTAATGGTGCAAAAGGCATTTTAGAAAAAGTTG
AGCATATTCAAATTGTTGCTTGTGGTACATCTTATAATGCAGGTATGGTGGCGCGTTATTGGTTTGAATCTTTAGCTGGC
GTGAGCTGTGATGTTGAAATTGCATCAGAATTTCGTTATCGCAAATTTGTTACCCGTCCAAATAGCTTATTGATTACCCT
TTCTCAATCTGGCGAAACAGCCGATACTTTAGCTGCACTTCGTTTAGCGAAAGAAAAGGGCTACATGGCAGCATTAACAA
TTTGTAATGTTGCTGGCTCTTCGCTCGTACGCGAATCAGATCTTGCATTTATGACTCGTGCTGGTGTTGAAGTTGGGGTG
GCATCGACAAAAGCATTTACGACACAGCTCGCTGCATTATTAATGCTGGTAACGGCACTTGGTAAAGTTAAAGGTCATAT
TTCTGTAGAAAAAGAACGTGAAATTATTAAAGCAATGCAATCTTTACCTGCTGAAATTGAAAAAGCGTTAGCCTTTGATT
CAGAAATTGAAGCTTTAGCAGAGGATTTTGCTGAAAAACATCATGCGCTTTTCTTAGGCCGTGGTGTGTTTTATCCAATT
GCGGTAGAGGCTTCTTTGAAATTGAAAGAGATTTCTTATATTCACGCTGAGGCCTATGCGGCAGGAGAATTGAAACACGG
GCCATTAGCGTTAATTGATGCTGATATGCCAGTGATTGTCGTTGCACCAAATAATGAATTATTAGAAAAAGTAAAATCGA
ACATTGAGGAAGTGCGAGCTCGTGGTGGTCAATTATACGTATTTGCCGATAAAGAAGCAGGATTTACGCCAAGTGAAGGA
ATGAAAATCATCACGATGCCAAAAGTCAATGATATTGTTGCACCGATTTTTTATACCATTCCAATGCAATTACTTTCTTA
TTATGTGGCTTTAATTAAAGGCACTGATGTAGATCAACCTCGTAACTTAGCAAAATCAGTTACCGTTGAATAA

Upstream 100 bases:

>100_bases
ATGAAATGAAGCCCTGTCGATTGCGCAGGGTTTTTTTTATTGTGTAAACGCGTGGCAAATGTAAAAACAAACTTAGTAAT
AGGATAAATAAGGAAAACTT

Downstream 100 bases:

>100_bases
AGTGCGGTTGATTTTAATGTAATAAAAAAACGGTAGAATTCACCGTATTTTTTAGTTAAATAATCTTCTTTGTTTCCGTG
TTTTAATCACTTGTGCGATT

Product: glucosamine--fructose-6-phosphate aminotransferase

Products: NA

Alternate protein names: D-fructose-6-phosphate amidotransferase; GFAT; Glucosamine-6-phosphate synthase; Hexosephosphate aminotransferase; L-glutamine-D-fructose-6-phosphate amidotransferase [H]

Number of amino acids: Translated: 610; Mature: 610

Protein sequence:

>610_residues
MCGIVGAVAQRDVAEILINGLHRLEYRGYDSAGVAVINKQNELQRIRCLGKVKALDEAVSEKPLIGGTGIAHTRWATHGE
PSETNAHPHSSGTFAVVHNGIIENHEELRELLKSRGYVFLSQTDTEVIAHLVEWEMRSTDSLLEAVQKSVKQLTGAYGMV
VMDSRHPEHLVAARSGSPLVIGLGIGENFLASDQLALLSVTRRFIFLEEGDIAEITRRTVDIYDTHGNKAKREIHESNLE
NDAAEKGKFRHFMQKEIYEQPTALINTMEGRINHENVIVDSIGNGAKGILEKVEHIQIVACGTSYNAGMVARYWFESLAG
VSCDVEIASEFRYRKFVTRPNSLLITLSQSGETADTLAALRLAKEKGYMAALTICNVAGSSLVRESDLAFMTRAGVEVGV
ASTKAFTTQLAALLMLVTALGKVKGHISVEKEREIIKAMQSLPAEIEKALAFDSEIEALAEDFAEKHHALFLGRGVFYPI
AVEASLKLKEISYIHAEAYAAGELKHGPLALIDADMPVIVVAPNNELLEKVKSNIEEVRARGGQLYVFADKEAGFTPSEG
MKIITMPKVNDIVAPIFYTIPMQLLSYYVALIKGTDVDQPRNLAKSVTVE

Sequences:

>Translated_610_residues
MCGIVGAVAQRDVAEILINGLHRLEYRGYDSAGVAVINKQNELQRIRCLGKVKALDEAVSEKPLIGGTGIAHTRWATHGE
PSETNAHPHSSGTFAVVHNGIIENHEELRELLKSRGYVFLSQTDTEVIAHLVEWEMRSTDSLLEAVQKSVKQLTGAYGMV
VMDSRHPEHLVAARSGSPLVIGLGIGENFLASDQLALLSVTRRFIFLEEGDIAEITRRTVDIYDTHGNKAKREIHESNLE
NDAAEKGKFRHFMQKEIYEQPTALINTMEGRINHENVIVDSIGNGAKGILEKVEHIQIVACGTSYNAGMVARYWFESLAG
VSCDVEIASEFRYRKFVTRPNSLLITLSQSGETADTLAALRLAKEKGYMAALTICNVAGSSLVRESDLAFMTRAGVEVGV
ASTKAFTTQLAALLMLVTALGKVKGHISVEKEREIIKAMQSLPAEIEKALAFDSEIEALAEDFAEKHHALFLGRGVFYPI
AVEASLKLKEISYIHAEAYAAGELKHGPLALIDADMPVIVVAPNNELLEKVKSNIEEVRARGGQLYVFADKEAGFTPSEG
MKIITMPKVNDIVAPIFYTIPMQLLSYYVALIKGTDVDQPRNLAKSVTVE
>Mature_610_residues
MCGIVGAVAQRDVAEILINGLHRLEYRGYDSAGVAVINKQNELQRIRCLGKVKALDEAVSEKPLIGGTGIAHTRWATHGE
PSETNAHPHSSGTFAVVHNGIIENHEELRELLKSRGYVFLSQTDTEVIAHLVEWEMRSTDSLLEAVQKSVKQLTGAYGMV
VMDSRHPEHLVAARSGSPLVIGLGIGENFLASDQLALLSVTRRFIFLEEGDIAEITRRTVDIYDTHGNKAKREIHESNLE
NDAAEKGKFRHFMQKEIYEQPTALINTMEGRINHENVIVDSIGNGAKGILEKVEHIQIVACGTSYNAGMVARYWFESLAG
VSCDVEIASEFRYRKFVTRPNSLLITLSQSGETADTLAALRLAKEKGYMAALTICNVAGSSLVRESDLAFMTRAGVEVGV
ASTKAFTTQLAALLMLVTALGKVKGHISVEKEREIIKAMQSLPAEIEKALAFDSEIEALAEDFAEKHHALFLGRGVFYPI
AVEASLKLKEISYIHAEAYAAGELKHGPLALIDADMPVIVVAPNNELLEKVKSNIEEVRARGGQLYVFADKEAGFTPSEG
MKIITMPKVNDIVAPIFYTIPMQLLSYYVALIKGTDVDQPRNLAKSVTVE

Specific function: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source [H]

COG id: COG0449

COG function: function code M; Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 SIS domains [H]

Homologues:

Organism=Homo sapiens, GI205277386, Length=685, Percent_Identity=38.978102189781, Blast_Score=441, Evalue=1e-123,
Organism=Homo sapiens, GI4826742, Length=686, Percent_Identity=38.3381924198251, Blast_Score=436, Evalue=1e-122,
Organism=Homo sapiens, GI29570798, Length=259, Percent_Identity=26.6409266409266, Blast_Score=72, Evalue=1e-12,
Organism=Escherichia coli, GI1790167, Length=610, Percent_Identity=72.2950819672131, Blast_Score=919, Evalue=0.0,
Organism=Escherichia coli, GI1788651, Length=228, Percent_Identity=29.8245614035088, Blast_Score=79, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI17539970, Length=435, Percent_Identity=40.2298850574713, Blast_Score=288, Evalue=6e-78,
Organism=Caenorhabditis elegans, GI17532897, Length=435, Percent_Identity=40, Blast_Score=286, Evalue=3e-77,
Organism=Caenorhabditis elegans, GI17532899, Length=435, Percent_Identity=40, Blast_Score=286, Evalue=3e-77,
Organism=Saccharomyces cerevisiae, GI6322745, Length=721, Percent_Identity=35.7836338418863, Blast_Score=390, Evalue=1e-109,
Organism=Saccharomyces cerevisiae, GI6323731, Length=431, Percent_Identity=32.0185614849188, Blast_Score=203, Evalue=8e-53,
Organism=Saccharomyces cerevisiae, GI6323730, Length=205, Percent_Identity=39.5121951219512, Blast_Score=133, Evalue=8e-32,
Organism=Drosophila melanogaster, GI21357745, Length=687, Percent_Identity=36.2445414847162, Blast_Score=419, Evalue=1e-117,
Organism=Drosophila melanogaster, GI28573187, Length=264, Percent_Identity=28.4090909090909, Blast_Score=81, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24659598, Length=269, Percent_Identity=27.5092936802974, Blast_Score=72, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000583
- InterPro:   IPR017932
- InterPro:   IPR005855
- InterPro:   IPR001347 [H]

Pfam domain/function: PF00310 GATase_2; PF01380 SIS [H]

EC number: =2.6.1.16 [H]

Molecular weight: Translated: 66863; Mature: 66863

Theoretical pI: Translated: 6.01; Mature: 6.01

Prosite motif: PS00443 GATASE_TYPE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCGIVGAVAQRDVAEILINGLHRLEYRGYDSAGVAVINKQNELQRIRCLGKVKALDEAVS
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHH
EKPLIGGTGIAHTRWATHGEPSETNAHPHSSGTFAVVHNGIIENHEELRELLKSRGYVFL
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCHHCCHHHHHHHHHHCCEEEE
SQTDTEVIAHLVEWEMRSTDSLLEAVQKSVKQLTGAYGMVVMDSRHPEHLVAARSGSPLV
ECCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCEEEECCCCCEE
IGLGIGENFLASDQLALLSVTRRFIFLEEGDIAEITRRTVDIYDTHGNKAKREIHESNLE
EEECCCCCCCCCCHHHHHHHHHHEEEEECCCHHHHHHHEEEEEECCCCHHHHHHHHHCCC
NDAAEKGKFRHFMQKEIYEQPTALINTMEGRINHENVIVDSIGNGAKGILEKVEHIQIVA
CHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHEEEEEE
CGTSYNAGMVARYWFESLAGVSCDVEIASEFRYRKFVTRPNSLLITLSQSGETADTLAAL
ECCCCCCCHHHHHHHHHHCCCEEEHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHH
RLAKEKGYMAALTICNVAGSSLVRESDLAFMTRAGVEVGVASTKAFTTQLAALLMLVTAL
HHHHHCCCEEEEHHHHHHCHHHHHHHHHHHHHHCCCEEECCCHHHHHHHHHHHHHHHHHH
GKVKGHISVEKEREIIKAMQSLPAEIEKALAFDSEIEALAEDFAEKHHALFLGRGVFYPI
HHHCCCEEEHHHHHHHHHHHHCHHHHHHHHHCCHHHHHHHHHHHHHHHEEEEECCCEEEE
AVEASLKLKEISYIHAEAYAAGELKHGPLALIDADMPVIVVAPNNELLEKVKSNIEEVRA
EEECCEEHHHHHHHHHHHHCCCCCCCCCEEEEECCCCEEEECCCHHHHHHHHHHHHHHHH
RGGQLYVFADKEAGFTPSEGMKIITMPKVNDIVAPIFYTIPMQLLSYYVALIKGTDVDQP
CCCEEEEEECCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
RNLAKSVTVE
HHHHHHCCCC
>Mature Secondary Structure
MCGIVGAVAQRDVAEILINGLHRLEYRGYDSAGVAVINKQNELQRIRCLGKVKALDEAVS
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHH
EKPLIGGTGIAHTRWATHGEPSETNAHPHSSGTFAVVHNGIIENHEELRELLKSRGYVFL
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCHHCCHHHHHHHHHHCCEEEE
SQTDTEVIAHLVEWEMRSTDSLLEAVQKSVKQLTGAYGMVVMDSRHPEHLVAARSGSPLV
ECCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCEEEECCCCCEE
IGLGIGENFLASDQLALLSVTRRFIFLEEGDIAEITRRTVDIYDTHGNKAKREIHESNLE
EEECCCCCCCCCCHHHHHHHHHHEEEEECCCHHHHHHHEEEEEECCCCHHHHHHHHHCCC
NDAAEKGKFRHFMQKEIYEQPTALINTMEGRINHENVIVDSIGNGAKGILEKVEHIQIVA
CHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHEEEEEE
CGTSYNAGMVARYWFESLAGVSCDVEIASEFRYRKFVTRPNSLLITLSQSGETADTLAAL
ECCCCCCCHHHHHHHHHHCCCEEEHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHH
RLAKEKGYMAALTICNVAGSSLVRESDLAFMTRAGVEVGVASTKAFTTQLAALLMLVTAL
HHHHHCCCEEEEHHHHHHCHHHHHHHHHHHHHHCCCEEECCCHHHHHHHHHHHHHHHHHH
GKVKGHISVEKEREIIKAMQSLPAEIEKALAFDSEIEALAEDFAEKHHALFLGRGVFYPI
HHHCCCEEEHHHHHHHHHHHHCHHHHHHHHHCCHHHHHHHHHHHHHHHEEEEECCCEEEE
AVEASLKLKEISYIHAEAYAAGELKHGPLALIDADMPVIVVAPNNELLEKVKSNIEEVRA
EEECCEEHHHHHHHHHHHHCCCCCCCCCEEEEECCCCEEEECCCHHHHHHHHHHHHHHHH
RGGQLYVFADKEAGFTPSEGMKIITMPKVNDIVAPIFYTIPMQLLSYYVALIKGTDVDQP
CCCEEEEEECCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
RNLAKSVTVE
HHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]