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The map label for this gene is nudC

Identifier: 148825288

GI number: 148825288

Start: 158877

End: 159671

Strand: Direct

Name: nudC

Synonym: CGSHiEE_00830

Alternate gene names: 148825288

Gene position: 158877-159671 (Clockwise)

Preceding gene: 148825287

Following gene: 148825289

Centisome position: 8.76

GC content: 38.49

Gene sequence:

>795_bases
ATGAAAATACTTCAACAAGATGATTTTGGTTATTGGTTGCTTACACAAGGTTCTAATCTGTATTTAGTGAATAATGAATT
GCCTTTTGGTATCGCTAAAGATATTGATTTGGAAGGATTACAGGCAATGCAAATTGGAGAATGGAAAAATCATCCGTTGT
GGCTTGTGGCTGAGCAAGAAAGTGATGAACGAGAATATGTGAGTTTGCGTAACTTGCTTTCACTGCCAGAGGATGAATTC
CATATATTAAGCCGAGGTGTGGAAATTAATCATTTTCTGAAAACCCATAAATTTTGTGGAAAGTGCGGTCATAAAACACA
ACAAACTCAAGATGAACTTGCAGTGCAATGTATTCACTGTGGGTATCAAACTTATCCTGTGATTTGCCCATCAATTATTG
TTGCGGTTCGTCGTGGTCACGAAATTCTATTGGCAAATCATAAGCGACATTATAGTCCTAACGGAGGAATATACACGACG
CTTGCAGGTTTTGTCGAAGTAGGGGAAACATTTGAACAAGCGGTGCAGAGAGAGGTTTTTGAAGAAACAGGGATTTCAAT
AAAAAATCTTCGTTATTTCGGTAGCCAACCTTGGGCATTTCCAAATTCTCAAATGGTCGGTTTTCTGGCTGATTATGAAA
GCGGAGAAATAACATTGCAGGAAAGTGAAATTCATGATGCACAATGGTTTTCTTATGATCAACCCTTGCCAGAATTACCG
CCAACGGGTACTATCGCTCGCAAATTAATTCATGTGACGCTTGAACTTTGTAAAGCGGAACATAAATGCGATTAA

Upstream 100 bases:

>100_bases
TGAGCATCAACGTGGCGAACATTCTTATTATTAGTGAGTTATAAAAGAAGATTTATAATGACCGCACTTTTGAAAGTGCG
GTTATTTTTATGGAGAAAAA

Downstream 100 bases:

>100_bases
TAAATATTCCAACTCTTACGAATTAAGGAAATAAGATGCGAAATCCGATTCATAAACGCTTAGAAAACTTAGACAGTTGG
CAACATCTTACTTTTATGGC

Product: NADH pyrophosphatase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 264; Mature: 264

Protein sequence:

>264_residues
MKILQQDDFGYWLLTQGSNLYLVNNELPFGIAKDIDLEGLQAMQIGEWKNHPLWLVAEQESDEREYVSLRNLLSLPEDEF
HILSRGVEINHFLKTHKFCGKCGHKTQQTQDELAVQCIHCGYQTYPVICPSIIVAVRRGHEILLANHKRHYSPNGGIYTT
LAGFVEVGETFEQAVQREVFEETGISIKNLRYFGSQPWAFPNSQMVGFLADYESGEITLQESEIHDAQWFSYDQPLPELP
PTGTIARKLIHVTLELCKAEHKCD

Sequences:

>Translated_264_residues
MKILQQDDFGYWLLTQGSNLYLVNNELPFGIAKDIDLEGLQAMQIGEWKNHPLWLVAEQESDEREYVSLRNLLSLPEDEF
HILSRGVEINHFLKTHKFCGKCGHKTQQTQDELAVQCIHCGYQTYPVICPSIIVAVRRGHEILLANHKRHYSPNGGIYTT
LAGFVEVGETFEQAVQREVFEETGISIKNLRYFGSQPWAFPNSQMVGFLADYESGEITLQESEIHDAQWFSYDQPLPELP
PTGTIARKLIHVTLELCKAEHKCD
>Mature_264_residues
MKILQQDDFGYWLLTQGSNLYLVNNELPFGIAKDIDLEGLQAMQIGEWKNHPLWLVAEQESDEREYVSLRNLLSLPEDEF
HILSRGVEINHFLKTHKFCGKCGHKTQQTQDELAVQCIHCGYQTYPVICPSIIVAVRRGHEILLANHKRHYSPNGGIYTT
LAGFVEVGETFEQAVQREVFEETGISIKNLRYFGSQPWAFPNSQMVGFLADYESGEITLQESEIHDAQWFSYDQPLPELP
PTGTIARKLIHVTLELCKAEHKCD

Specific function: Unknown

COG id: COG2816

COG function: function code L; NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain

Homologues:

Organism=Homo sapiens, GI13899267, Length=199, Percent_Identity=35.1758793969849, Blast_Score=111, Evalue=6e-25,
Organism=Homo sapiens, GI50593112, Length=182, Percent_Identity=32.4175824175824, Blast_Score=94, Evalue=1e-19,
Organism=Escherichia coli, GI48994995, Length=261, Percent_Identity=47.5095785440613, Blast_Score=261, Evalue=3e-71,
Organism=Caenorhabditis elegans, GI212645999, Length=180, Percent_Identity=27.7777777777778, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI71986510, Length=206, Percent_Identity=25.7281553398058, Blast_Score=82, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6321371, Length=211, Percent_Identity=30.8056872037915, Blast_Score=86, Evalue=4e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NUDC_HAEI8 (Q4QNB3)

Other databases:

- EMBL:   CP000057
- RefSeq:   YP_248144.1
- ProteinModelPortal:   Q4QNB3
- SMR:   Q4QNB3
- STRING:   Q4QNB3
- GeneID:   3429870
- GenomeReviews:   CP000057_GR
- KEGG:   hit:NTHI0557
- eggNOG:   COG2816
- HOGENOM:   HBG736436
- OMA:   SPCIIVA
- PhylomeDB:   Q4QNB3
- ProtClustDB:   PRK00241
- BioCyc:   HINF281310:NTHI0557-MONOMER
- HAMAP:   MF_00297
- InterPro:   IPR015375
- InterPro:   IPR022925
- InterPro:   IPR020084
- InterPro:   IPR000086
- InterPro:   IPR015797
- InterPro:   IPR015376
- Gene3D:   G3DSA:3.90.79.10

Pfam domain/function: PF00293 NUDIX; PF09296 NUDIX-like; PF09297 zf-NADH-PPase; SSF55811 NUDIX_hydrolase

EC number: =3.6.1.22

Molecular weight: Translated: 30207; Mature: 30207

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: PS51462 NUDIX; PS00893 NUDIX_BOX

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKILQQDDFGYWLLTQGSNLYLVNNELPFGIAKDIDLEGLQAMQIGEWKNHPLWLVAEQE
CCCCCCCCCCEEEEECCCEEEEEECCCCCCCCCCCCCCCCCEEECCCCCCCCEEEEECCC
SDEREYVSLRNLLSLPEDEFHILSRGVEINHFLKTHKFCGKCGHKTQQTQDELAVQCIHC
CCHHHHHHHHHHHCCCCHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHC
GYQTYPVICPSIIVAVRRGHEILLANHKRHYSPNGGIYTTLAGFVEVGETFEQAVQREVF
CCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
EETGISIKNLRYFGSQPWAFPNSQMVGFLADYESGEITLQESEIHDAQWFSYDQPLPELP
HHHCCCEEEEEEECCCCCCCCCCCEEEEEEECCCCEEEEECCCCCCCHHCCCCCCCCCCC
PTGTIARKLIHVTLELCKAEHKCD
CCHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKILQQDDFGYWLLTQGSNLYLVNNELPFGIAKDIDLEGLQAMQIGEWKNHPLWLVAEQE
CCCCCCCCCCEEEEECCCEEEEEECCCCCCCCCCCCCCCCCEEECCCCCCCCEEEEECCC
SDEREYVSLRNLLSLPEDEFHILSRGVEINHFLKTHKFCGKCGHKTQQTQDELAVQCIHC
CCHHHHHHHHHHHCCCCHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHC
GYQTYPVICPSIIVAVRRGHEILLANHKRHYSPNGGIYTTLAGFVEVGETFEQAVQREVF
CCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
EETGISIKNLRYFGSQPWAFPNSQMVGFLADYESGEITLQESEIHDAQWFSYDQPLPELP
HHHCCCEEEEEEECCCCCCCCCCCEEEEEEECCCCEEEEECCCCCCCHHCCCCCCCCCCC
PTGTIARKLIHVTLELCKAEHKCD
CCHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA