Click here to switch to the map view.

The map label for this gene is ytfL [C]

Identifier: 148825268

GI number: 148825268

Start: 139627

End: 140919

Strand: Direct

Name: ytfL [C]

Synonym: CGSHiEE_00730

Alternate gene names: 148825268

Gene position: 139627-140919 (Clockwise)

Preceding gene: 148825267

Following gene: 148825269

Centisome position: 7.7

GC content: 37.66

Gene sequence:

>1293_bases
ATGGAATTATTTCATACTATTTTGGCAATTGTGGCTTTAATTTTAAGTAGTGCAGTTGTTTCTTCTGCTGAAATTTCTCT
GGCGAGTTCTCGTAAGTTAAAATTGCAATCTCTTGCAAATGAAGGCGATGTGCGCGCACTTCAAGTGCTTAAATTACAAG
AGCATCCTGGTCGTTTTATTACGGTGGTTCAAATTTTGTTGAATATGGTGGCGATTTTGGGTGGGGGAATTGGCGAAAGT
GCGCTAAGTCCTTATATTGCAGATATTTTAAATCGTTCTTTTGAAGGAAATTGGATTGAGCCAACCGCCTCTACAATCGC
TTTTATATTAGTGACTTGTTTGTTTATTTTATTTGCCGATCTTATTCCAAAACGAATTGCTATTACTTATCCTGAAATGG
TGGCGTTGCGCGTTGTGGGTATTATGAATTTTAGTATGTATGTGTTTAAACCGCTTGTGTGGTTTTTTGATACGCTTGCT
AATGCCTTTTTCCGTCTATTTCGCATTTCTACTGTGCGTGAAGATGGCATGACCTCTGAAGATATTTTCGCCGTAGTTGA
AGCAGGCGCAGAAGCTGGTGTATTAAAAACTCAAGAGCATTATTTGATCGAAAATATTTTCGATATGCAAGCCCGTACGG
TAACTTCCACAATGACAACCCGTGAAAACATCGTATATTTAGACCGCACTTTTTCTCGCCAAGAAGTGATGGATACGCTT
TCTCGTAATTCCCATTCTAAAATTGTGATTTGTGACAATGGCCTCGACAAAATCTTAGGTTATATCGAATCCCATACTTT
GCTCACAATGTATTTGCAAAATGAAAATGTGGTGCTCACAGATCCTAAACTACTCCGTAAAGCACTATTTGTGCCTGATA
CGCTTTCTCTTTACGAAGTGTTGGAATTGTTTAAATCTACTGGCGAAGATTTTGCGATTATTGTGAATGAATATGCTCTT
GTAGTGGGTATTGTTACGCTAAATGATGTGATGAGTATTGTTATGGGGGAATTGGTTTCTAACGAAGAAGAATATATTGT
GAGCCGTGATGAAAACTCGTGGCTGATTGATGGTGCAACGCCATTAGAAGAGGTAACTCGAGTATTAGATATTGCTTATT
TTCCCGATGAAGAAAACTACGAAACTATCAGTGGTTTTATGATGTATATGTTACGTAAAATCCCGAAAAAAACCGATTCT
GTGGTTTACGGAAAATACAAGTTTGAAGTGATTGATACGGAAAACTTTAAAATCGATCAGATTTTGGTGTCTTTAGTAAA
AGAGCAGGAGTAG

Upstream 100 bases:

>100_bases
TGTCTATCCAATTTATTCGCGGCTGGTTTGACAGCGATAAGTAATATCCCAAACGGTCGCAAAGTGCGGTCGTTTTCTTT
TATATTTTTGAGTAATGATT

Downstream 100 bases:

>100_bases
AAGTGCGGTAAATTTTTATCCATTTCTCTACAAAATTATGTTATAAAACCATAAAAAATTTGAGGTTAAATATGGAACTA
AGACAACAAATTCCAACAGG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 430; Mature: 430

Protein sequence:

>430_residues
MELFHTILAIVALILSSAVVSSAEISLASSRKLKLQSLANEGDVRALQVLKLQEHPGRFITVVQILLNMVAILGGGIGES
ALSPYIADILNRSFEGNWIEPTASTIAFILVTCLFILFADLIPKRIAITYPEMVALRVVGIMNFSMYVFKPLVWFFDTLA
NAFFRLFRISTVREDGMTSEDIFAVVEAGAEAGVLKTQEHYLIENIFDMQARTVTSTMTTRENIVYLDRTFSRQEVMDTL
SRNSHSKIVICDNGLDKILGYIESHTLLTMYLQNENVVLTDPKLLRKALFVPDTLSLYEVLELFKSTGEDFAIIVNEYAL
VVGIVTLNDVMSIVMGELVSNEEEYIVSRDENSWLIDGATPLEEVTRVLDIAYFPDEENYETISGFMMYMLRKIPKKTDS
VVYGKYKFEVIDTENFKIDQILVSLVKEQE

Sequences:

>Translated_430_residues
MELFHTILAIVALILSSAVVSSAEISLASSRKLKLQSLANEGDVRALQVLKLQEHPGRFITVVQILLNMVAILGGGIGES
ALSPYIADILNRSFEGNWIEPTASTIAFILVTCLFILFADLIPKRIAITYPEMVALRVVGIMNFSMYVFKPLVWFFDTLA
NAFFRLFRISTVREDGMTSEDIFAVVEAGAEAGVLKTQEHYLIENIFDMQARTVTSTMTTRENIVYLDRTFSRQEVMDTL
SRNSHSKIVICDNGLDKILGYIESHTLLTMYLQNENVVLTDPKLLRKALFVPDTLSLYEVLELFKSTGEDFAIIVNEYAL
VVGIVTLNDVMSIVMGELVSNEEEYIVSRDENSWLIDGATPLEEVTRVLDIAYFPDEENYETISGFMMYMLRKIPKKTDS
VVYGKYKFEVIDTENFKIDQILVSLVKEQE
>Mature_430_residues
MELFHTILAIVALILSSAVVSSAEISLASSRKLKLQSLANEGDVRALQVLKLQEHPGRFITVVQILLNMVAILGGGIGES
ALSPYIADILNRSFEGNWIEPTASTIAFILVTCLFILFADLIPKRIAITYPEMVALRVVGIMNFSMYVFKPLVWFFDTLA
NAFFRLFRISTVREDGMTSEDIFAVVEAGAEAGVLKTQEHYLIENIFDMQARTVTSTMTTRENIVYLDRTFSRQEVMDTL
SRNSHSKIVICDNGLDKILGYIESHTLLTMYLQNENVVLTDPKLLRKALFVPDTLSLYEVLELFKSTGEDFAIIVNEYAL
VVGIVTLNDVMSIVMGELVSNEEEYIVSRDENSWLIDGATPLEEVTRVLDIAYFPDEENYETISGFMMYMLRKIPKKTDS
VVYGKYKFEVIDTENFKIDQILVSLVKEQE

Specific function: Unknown

COG id: COG1253

COG function: function code R; Hemolysins and related proteins containing CBS domains

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=378, Percent_Identity=23.5449735449735, Blast_Score=120, Evalue=4e-27,
Organism=Escherichia coli, GI1790664, Length=428, Percent_Identity=53.9719626168224, Blast_Score=478, Evalue=1e-136,
Organism=Escherichia coli, GI145693175, Length=419, Percent_Identity=25.0596658711217, Blast_Score=134, Evalue=8e-33,
Organism=Escherichia coli, GI87082033, Length=277, Percent_Identity=30.6859205776173, Blast_Score=133, Evalue=3e-32,
Organism=Escherichia coli, GI1788119, Length=237, Percent_Identity=27.4261603375527, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1786879, Length=277, Percent_Identity=22.3826714801444, Blast_Score=86, Evalue=5e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR002550
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC; PF01595 DUF21 [H]

EC number: NA

Molecular weight: Translated: 48554; Mature: 48554

Theoretical pI: Translated: 4.41; Mature: 4.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELFHTILAIVALILSSAVVSSAEISLASSRKLKLQSLANEGDVRALQVLKLQEHPGRFI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCHHHHHHHHHHCCCCHHH
TVVQILLNMVAILGGGIGESALSPYIADILNRSFEGNWIEPTASTIAFILVTCLFILFAD
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
LIPKRIAITYPEMVALRVVGIMNFSMYVFKPLVWFFDTLANAFFRLFRISTVREDGMTSE
HCCHHEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
DIFAVVEAGAEAGVLKTQEHYLIENIFDMQARTVTSTMTTRENIVYLDRTFSRQEVMDTL
HHHHHHHCCCCCCCEECHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHH
SRNSHSKIVICDNGLDKILGYIESHTLLTMYLQNENVVLTDPKLLRKALFVPDTLSLYEV
HCCCCCEEEEECCCHHHHHHHHCCCEEEEEEEECCCEEEECHHHHHHHHCCCCHHHHHHH
LELFKSTGEDFAIIVNEYALVVGIVTLNDVMSIVMGELVSNEEEYIVSRDENSWLIDGAT
HHHHHCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCEEEECCC
PLEEVTRVLDIAYFPDEENYETISGFMMYMLRKIPKKTDSVVYGKYKFEVIDTENFKIDQ
CHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEEEEEEEECCCCCHHH
ILVSLVKEQE
HHHHHHHCCC
>Mature Secondary Structure
MELFHTILAIVALILSSAVVSSAEISLASSRKLKLQSLANEGDVRALQVLKLQEHPGRFI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCHHHHHHHHHHCCCCHHH
TVVQILLNMVAILGGGIGESALSPYIADILNRSFEGNWIEPTASTIAFILVTCLFILFAD
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
LIPKRIAITYPEMVALRVVGIMNFSMYVFKPLVWFFDTLANAFFRLFRISTVREDGMTSE
HCCHHEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
DIFAVVEAGAEAGVLKTQEHYLIENIFDMQARTVTSTMTTRENIVYLDRTFSRQEVMDTL
HHHHHHHCCCCCCCEECHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHH
SRNSHSKIVICDNGLDKILGYIESHTLLTMYLQNENVVLTDPKLLRKALFVPDTLSLYEV
HCCCCCEEEEECCCHHHHHHHHCCCEEEEEEEECCCEEEECHHHHHHHHCCCCHHHHHHH
LELFKSTGEDFAIIVNEYALVVGIVTLNDVMSIVMGELVSNEEEYIVSRDENSWLIDGAT
HHHHHCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCEEEECCC
PLEEVTRVLDIAYFPDEENYETISGFMMYMLRKIPKKTDSVVYGKYKFEVIDTENFKIDQ
CHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEEEEEEEECCCCCHHH
ILVSLVKEQE
HHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]