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The map label for this gene is atpB [H]

Identifier: 148825236

GI number: 148825236

Start: 108273

End: 109061

Strand: Direct

Name: atpB [H]

Synonym: CGSHiEE_00560

Alternate gene names: 148825236

Gene position: 108273-109061 (Clockwise)

Preceding gene: 148825235

Following gene: 148825237

Centisome position: 5.97

GC content: 36.12

Gene sequence:

>789_bases
ATGTTTGGACAAACAACATCGGAATACATTAGCCACCATTTATCCTTTCTCAAAACAGGGGATGGGTTTTGGAATGTTCA
TATAGATACGTTGTTCTTTTCTATTCTTGCTGCGGTTATTTTCCTATTTGTTTTTTCTCGAGTAGGGAAAAAAGCAACAA
CTGGCGTTCCAGGAAAAATGCAATGCTTAGTTGAAATTGTTGTGGAATGGGTTAATGGAATCGTGAAAGAAAATTTTCAT
GGTCCACGTAACGTAGTTGCGCCGCTTGCATTAACCATTTTCTGTTGGGTATTCATCATGAATGCTATCGACTTAATTCC
TGTTGATTTCTTACCTCAATTTGCAGGTTTGTTCGGTATTCATTATCTTCGTGCAGTGCCGACAGCAGATATTAGCGCAA
CTTTGGGTATGTCCATTTGTGTTTTCTTTTTAATTCTTTTCTACACAATAAAATCTAAAGGATTCAAAGGTTTAGTTAAA
GAATATACGCTTCATCCATTCAATCATTGGGCGTTTATTCCTGTTAACTTTATTCTTGAAACTGTGACTTTATTGGCTAA
ACCAATTTCACTTGCTTTCCGTTTATTCGGTAACATGTATGCAGGGGAATTGATCTTTATTCTTATCGCTGTGATGTATT
CCGCTAATATGGCCATTGCAGCATTAGGGATTCCGTTACATCTTGCTTGGGCTATTTTCCATATTTTGGTTATTACCTTG
CAGGCTTTCATCTTTATGATGTTGACGGTTGTTTATTTAAGTATTGCTTATAACAAAGCAGATCATTAA

Upstream 100 bases:

>100_bases
TATTTTTTTTAGTGGTTTTTTTATTGCATTAATGTTGAATAATTTAGTTCCATTTTTGCTTCGCCGAATTTGATTTTTAT
ACTTGTACTAAGGGTTTATT

Downstream 100 bases:

>100_bases
TCATTTTCTATTAACCGGCTCTAGGGCTAAAACTTAACTTCTATTGGAGAAAATTATGGAAACTGTAATTACAGCTACAA
TCATCGGTGCATCAATTCTT

Product: F0F1 ATP synthase subunit A

Products: ADP; phosphate; H+

Alternate protein names: ATP synthase F0 sector subunit a; F-ATPase subunit 6 [H]

Number of amino acids: Translated: 262; Mature: 262

Protein sequence:

>262_residues
MFGQTTSEYISHHLSFLKTGDGFWNVHIDTLFFSILAAVIFLFVFSRVGKKATTGVPGKMQCLVEIVVEWVNGIVKENFH
GPRNVVAPLALTIFCWVFIMNAIDLIPVDFLPQFAGLFGIHYLRAVPTADISATLGMSICVFFLILFYTIKSKGFKGLVK
EYTLHPFNHWAFIPVNFILETVTLLAKPISLAFRLFGNMYAGELIFILIAVMYSANMAIAALGIPLHLAWAIFHILVITL
QAFIFMMLTVVYLSIAYNKADH

Sequences:

>Translated_262_residues
MFGQTTSEYISHHLSFLKTGDGFWNVHIDTLFFSILAAVIFLFVFSRVGKKATTGVPGKMQCLVEIVVEWVNGIVKENFH
GPRNVVAPLALTIFCWVFIMNAIDLIPVDFLPQFAGLFGIHYLRAVPTADISATLGMSICVFFLILFYTIKSKGFKGLVK
EYTLHPFNHWAFIPVNFILETVTLLAKPISLAFRLFGNMYAGELIFILIAVMYSANMAIAALGIPLHLAWAIFHILVITL
QAFIFMMLTVVYLSIAYNKADH
>Mature_262_residues
MFGQTTSEYISHHLSFLKTGDGFWNVHIDTLFFSILAAVIFLFVFSRVGKKATTGVPGKMQCLVEIVVEWVNGIVKENFH
GPRNVVAPLALTIFCWVFIMNAIDLIPVDFLPQFAGLFGIHYLRAVPTADISATLGMSICVFFLILFYTIKSKGFKGLVK
EYTLHPFNHWAFIPVNFILETVTLLAKPISLAFRLFGNMYAGELIFILIAVMYSANMAIAALGIPLHLAWAIFHILVITL
QAFIFMMLTVVYLSIAYNKADH

Specific function: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane [H]

COG id: COG0356

COG function: function code C; F0F1-type ATP synthase, subunit a

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase A chain family [H]

Homologues:

Organism=Escherichia coli, GI1790176, Length=272, Percent_Identity=53.6764705882353, Blast_Score=269, Evalue=2e-73,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000568
- InterPro:   IPR023011 [H]

Pfam domain/function: PF00119 ATP-synt_A [H]

EC number: 3.6.3.14

Molecular weight: Translated: 29394; Mature: 29394

Theoretical pI: Translated: 8.47; Mature: 8.47

Prosite motif: PS00449 ATPASE_A

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure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HHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: Borate; diphosphate; HCO3- [C]

Metal ions: Co2+; Fe2+; Mn2+; Zn2+ [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O; H+

Specific reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out)

General reaction: Phosphorous acid anhydride hydrolysis [C]

Inhibitor: Ca2+; CN-; Efrapeptin; Ethidiumbromide; Guanidines analogs; Oligomycin; Quercetin; Trialkyl tin derivatives; Venturicidin [C]

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA