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The map label for this gene is cysQ [H]

Identifier: 148825165

GI number: 148825165

Start: 36128

End: 36937

Strand: Direct

Name: cysQ [H]

Synonym: CGSHiEE_00185

Alternate gene names: 148825165

Gene position: 36128-36937 (Clockwise)

Preceding gene: 148825164

Following gene: 148825166

Centisome position: 1.99

GC content: 38.77

Gene sequence:

>810_bases
ATGCTGACGCTAAACGAACACTTACTTAACCAAGTATTGCTGATTGCTTACCAAGCAGGTAAGCATTTGCAACAGTTTTA
TCAAAAACAGGTTCATGTTGAATTGAAAGAAGACAACACGCCTGTGACGGAAGCGGATCTTTTTGTGAGCCAATTTTTAA
CCGAAAAATTGACCGCACTTTTCCCTAATATCCCCGTTCTTTCGGAAGAAAATTGTCATATTTCCTTTGAAGAACGTAAA
AATTGGAAAGAATATTGGTTGATTGATCCTCTTGATGGCACACAACAATTTATTAATCGTACCGATCAATTTTCTGTGTT
GATAACCTTAGTTCGTAAAAATAAACCCGTGTTAAGTGTTATTCATGCACCAATTTTATCGACAACTTATTATGCAATGC
GTGATTTCGGTGCGTTTAAAAAACAACTGGATCAGGTAAAAAAACTCACTAAAAACACGACAAATTTTGACCGCCCTTTA
CGAATTGCGGTAGGTGCAACCACTTCACAAGAAAAAGTGCGGTCGATTTTGCCGAAGGATTTTACTTGTGAATTTGTTGT
GGTTGGTTCAAGTAGCTTAAAAAGCGGTTTGGTGGCTGAAGGTGCAGTAGATTGTTATGTTCGTTTAGGACAAACAGGCG
AATGGGATACCGCTGGCGCAGAAGTGTTGCTGAATGAAACTCACGGTGCCATTTTTGACTCTCATTTTGAGCCTTTAACC
TATAACCAACGCGAAACATTGATTAATCCGCATTTTGTTATGGTGGGCGATCAATCGTTCGATTGGCGTTCTGTCTTTCA
ATTTAATTGA

Upstream 100 bases:

>100_bases
GAAGGGGGATTGTCCCTCGGGTTAATAAGCACATGCGGAATGGTTTTTTATGCTCTATTTGTAATGCCTTGGTTGCTGCC
AAAAACAAGAGAATAATTTT

Downstream 100 bases:

>100_bases
TTGGTTCGATTGGTTTTTTTCTCTAGAATACGGCATTATTTTCGACATTACTCGGAAGCCGAATAAGGAATAATTATGCA
AACTGATAATAATTGTATCG

Product: DNA-binding transcriptional regulator AsnC

Products: NA

Alternate protein names: 3'(2'),5-bisphosphonucleoside 3'(2')-phosphohydrolase; 3'-phosphoadenosine 5'-phosphate phosphatase; PAP phosphatase; DPNPase [H]

Number of amino acids: Translated: 269; Mature: 269

Protein sequence:

>269_residues
MLTLNEHLLNQVLLIAYQAGKHLQQFYQKQVHVELKEDNTPVTEADLFVSQFLTEKLTALFPNIPVLSEENCHISFEERK
NWKEYWLIDPLDGTQQFINRTDQFSVLITLVRKNKPVLSVIHAPILSTTYYAMRDFGAFKKQLDQVKKLTKNTTNFDRPL
RIAVGATTSQEKVRSILPKDFTCEFVVVGSSSLKSGLVAEGAVDCYVRLGQTGEWDTAGAEVLLNETHGAIFDSHFEPLT
YNQRETLINPHFVMVGDQSFDWRSVFQFN

Sequences:

>Translated_269_residues
MLTLNEHLLNQVLLIAYQAGKHLQQFYQKQVHVELKEDNTPVTEADLFVSQFLTEKLTALFPNIPVLSEENCHISFEERK
NWKEYWLIDPLDGTQQFINRTDQFSVLITLVRKNKPVLSVIHAPILSTTYYAMRDFGAFKKQLDQVKKLTKNTTNFDRPL
RIAVGATTSQEKVRSILPKDFTCEFVVVGSSSLKSGLVAEGAVDCYVRLGQTGEWDTAGAEVLLNETHGAIFDSHFEPLT
YNQRETLINPHFVMVGDQSFDWRSVFQFN
>Mature_269_residues
MLTLNEHLLNQVLLIAYQAGKHLQQFYQKQVHVELKEDNTPVTEADLFVSQFLTEKLTALFPNIPVLSEENCHISFEERK
NWKEYWLIDPLDGTQQFINRTDQFSVLITLVRKNKPVLSVIHAPILSTTYYAMRDFGAFKKQLDQVKKLTKNTTNFDRPL
RIAVGATTSQEKVRSILPKDFTCEFVVVGSSSLKSGLVAEGAVDCYVRLGQTGEWDTAGAEVLLNETHGAIFDSHFEPLT
YNQRETLINPHFVMVGDQSFDWRSVFQFN

Specific function: Converts 3'(2')-phosphoadenosine 5'-phosphate (PAP) to AMP. May also convert adenosine 3'-phosphate 5'-phosphosulfate (PAPS) to adenosine 5'-phosphosulfate (APS) [H]

COG id: COG1218

COG function: function code P; 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase

Gene ontology:

Cell location: Cytoplasm. Cell inner membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the inositol monophosphatase family [H]

Homologues:

Organism=Homo sapiens, GI5031789, Length=253, Percent_Identity=25.6916996047431, Blast_Score=81, Evalue=9e-16,
Organism=Homo sapiens, GI221625487, Length=253, Percent_Identity=25.6916996047431, Blast_Score=81, Evalue=9e-16,
Organism=Escherichia coli, GI1790659, Length=247, Percent_Identity=35.2226720647773, Blast_Score=146, Evalue=1e-36,
Organism=Escherichia coli, GI1788882, Length=232, Percent_Identity=26.7241379310345, Blast_Score=77, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI193202572, Length=237, Percent_Identity=26.1603375527426, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI193202570, Length=240, Percent_Identity=27.0833333333333, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI71995905, Length=165, Percent_Identity=24.8484848484848, Blast_Score=64, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI71995897, Length=165, Percent_Identity=24.8484848484848, Blast_Score=64, Evalue=7e-11,
Organism=Saccharomyces cerevisiae, GI6320493, Length=235, Percent_Identity=24.6808510638298, Blast_Score=64, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24664918, Length=265, Percent_Identity=25.2830188679245, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24664922, Length=226, Percent_Identity=25.6637168141593, Blast_Score=66, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006240
- InterPro:   IPR020583
- InterPro:   IPR000760
- InterPro:   IPR020550 [H]

Pfam domain/function: PF00459 Inositol_P [H]

EC number: =3.1.3.7 [H]

Molecular weight: Translated: 30791; Mature: 30791

Theoretical pI: Translated: 6.09; Mature: 6.09

Prosite motif: PS00629 IMP_1 ; PS00630 IMP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTLNEHLLNQVLLIAYQAGKHLQQFYQKQVHVELKEDNTPVTEADLFVSQFLTEKLTAL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCHHHHHHHHHHHHHHHHHH
FPNIPVLSEENCHISFEERKNWKEYWLIDPLDGTQQFINRTDQFSVLITLVRKNKPVLSV
CCCCCCCCCCCCEEEHHHHCCCCCEEEECCCCHHHHHHCCCCHHHEEEEEHHCCCCHHHH
IHAPILSTTYYAMRDFGAFKKQLDQVKKLTKNTTNFDRPLRIAVGATTSQEKVRSILPKD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCHHHHHHHCCCC
FTCEFVVVGSSSLKSGLVAEGAVDCYVRLGQTGEWDTAGAEVLLNETHGAIFDSHFEPLT
CCEEEEEECCCCHHCCCHHCCCEEEEEEECCCCCCCCCCCEEEEECCCCCEECCCCCCCC
YNQRETLINPHFVMVGDQSFDWRSVFQFN
CCCHHHCCCCEEEEECCCCCCHHHHEECC
>Mature Secondary Structure
MLTLNEHLLNQVLLIAYQAGKHLQQFYQKQVHVELKEDNTPVTEADLFVSQFLTEKLTAL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCHHHHHHHHHHHHHHHHHH
FPNIPVLSEENCHISFEERKNWKEYWLIDPLDGTQQFINRTDQFSVLITLVRKNKPVLSV
CCCCCCCCCCCCEEEHHHHCCCCCEEEECCCCHHHHHHCCCCHHHEEEEEHHCCCCHHHH
IHAPILSTTYYAMRDFGAFKKQLDQVKKLTKNTTNFDRPLRIAVGATTSQEKVRSILPKD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCHHHHHHHCCCC
FTCEFVVVGSSSLKSGLVAEGAVDCYVRLGQTGEWDTAGAEVLLNETHGAIFDSHFEPLT
CCEEEEEECCCCHHCCCHHCCCEEEEEEECCCCCCCCCCCEEEEECCCCCEECCCCCCCC
YNQRETLINPHFVMVGDQSFDWRSVFQFN
CCCHHHCCCCEEEEECCCCCCHHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]