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The map label for this gene is ppe59

Identifier: 148824638

GI number: 148824638

Start: 3860876

End: 3861412

Strand: Direct

Name: ppe59

Synonym: TBFG_13465

Alternate gene names: 148824638

Gene position: 3860876-3861412 (Clockwise)

Preceding gene: 148824636

Following gene: 148824647

Centisome position: 87.26

GC content: 56.05

Gene sequence:

>537_bases
ATGCATCCAATGATACCAGCGGAGTATATCTCCAACATAATATATGAAGGTCCGGGTGCTGACTCATTGTCTGCCGCCGC
CGAGCAATTGCGACTAATGTATAACTCAGCTAACATGACGGCTAAGTCGCTCACCGACAGGCTCGGCGAGCTGCAGGAGA
ACTGGAAAGGTAGTTCGTCGGACTTGATGGCCGACGCGGCTGGGCGGTATCTCGACTGGCTGACTAAACACTCTCGTCAA
ATTCTGGAAACCGCCTACGTGATCGACTTCCTCGCATACGTCTATGAGGAGACACGTCACAAGGTGGTACCCCCGGCGAC
TATCGCCAACAACCGCGAGGAGGTGCACAGGCTGATCGCGAGCAACGTGGCCGGGGTAAACACTCCAGCAATCGCAGGAC
TCGATGCACAATATCAGCAGTACCGGGCCCAAAATATCGCTGTCATGAACGACTATCAAAGTACCGCCCGGTTTATCCTA
GCGTATCTGCCCCGATGGCAGGAGCCGCCGCAGATCTACGGGGGCGGGGGCGGGTAG

Upstream 100 bases:

>100_bases
ACAACCTTGCACTGATCTAGCTGAAGACCAAACCGGCACAGCAGACATTGCCATACGCGACAACAGCCGTCATCAACCGA
AAGGAGCAAAGAACAAACAG

Downstream 100 bases:

>100_bases
GTCCAGAAGGCCGGGGCGGAACCTGTCAACATTTCTGAGACACGATTTTCGGGGATTTATTGAGTCGGCTGGTCCTCCTT
CGGTGGTGGGTTGATCGCGC

Product: PPE family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 178; Mature: 178

Protein sequence:

>178_residues
MHPMIPAEYISNIIYEGPGADSLSAAAEQLRLMYNSANMTAKSLTDRLGELQENWKGSSSDLMADAAGRYLDWLTKHSRQ
ILETAYVIDFLAYVYEETRHKVVPPATIANNREEVHRLIASNVAGVNTPAIAGLDAQYQQYRAQNIAVMNDYQSTARFIL
AYLPRWQEPPQIYGGGGG

Sequences:

>Translated_178_residues
MHPMIPAEYISNIIYEGPGADSLSAAAEQLRLMYNSANMTAKSLTDRLGELQENWKGSSSDLMADAAGRYLDWLTKHSRQ
ILETAYVIDFLAYVYEETRHKVVPPATIANNREEVHRLIASNVAGVNTPAIAGLDAQYQQYRAQNIAVMNDYQSTARFIL
AYLPRWQEPPQIYGGGGG
>Mature_178_residues
MHPMIPAEYISNIIYEGPGADSLSAAAEQLRLMYNSANMTAKSLTDRLGELQENWKGSSSDLMADAAGRYLDWLTKHSRQ
ILETAYVIDFLAYVYEETRHKVVPPATIANNREEVHRLIASNVAGVNTPAIAGLDAQYQQYRAQNIAVMNDYQSTARFIL
AYLPRWQEPPQIYGGGGG

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mycobacterial PPE family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PPE59_MYCTU (O06246)

Other databases:

- EMBL:   BX842583
- EMBL:   AE000516
- PIR:   C70975
- RefSeq:   NP_338059.1
- RefSeq:   YP_177973.1
- ProteinModelPortal:   O06246
- SMR:   O06246
- EnsemblBacteria:   EBMYCT00000002726
- EnsemblBacteria:   EBMYCT00000072084
- GeneID:   887630
- GeneID:   925711
- GenomeReviews:   AE000516_GR
- GenomeReviews:   AL123456_GR
- KEGG:   mtc:MT3533
- KEGG:   mtu:Rv3429
- TIGR:   MT3533
- TubercuList:   Rv3429
- GeneTree:   EBGT00050000014891
- HOGENOM:   HBG572308
- OMA:   IASNXAG
- ProtClustDB:   CLSK799991
- InterPro:   IPR000030

Pfam domain/function: PF00823 PPE

EC number: NA

Molecular weight: Translated: 19812; Mature: 19812

Theoretical pI: Translated: 5.21; Mature: 5.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHPMIPAEYISNIIYEGPGADSLSAAAEQLRLMYNSANMTAKSLTDRLGELQENWKGSSS
CCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCH
DLMADAAGRYLDWLTKHSRQILETAYVIDFLAYVYEETRHKVVPPATIANNREEVHRLIA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCHHHHHHHHH
SNVAGVNTPAIAGLDAQYQQYRAQNIAVMNDYQSTARFILAYLPRWQEPPQIYGGGGG
HHCCCCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure
MHPMIPAEYISNIIYEGPGADSLSAAAEQLRLMYNSANMTAKSLTDRLGELQENWKGSSS
CCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCH
DLMADAAGRYLDWLTKHSRQILETAYVIDFLAYVYEETRHKVVPPATIANNREEVHRLIA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCHHHHHHHHH
SNVAGVNTPAIAGLDAQYQQYRAQNIAVMNDYQSTARFILAYLPRWQEPPQIYGGGGG
HHCCCCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036