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The map label for this gene is yhdE [C]

Identifier: 148824484

GI number: 148824484

Start: 3675934

End: 3676602

Strand: Direct

Name: yhdE [C]

Synonym: TBFG_13311

Alternate gene names: 148824484

Gene position: 3675934-3676602 (Clockwise)

Preceding gene: 148824483

Following gene: 148824485

Centisome position: 83.08

GC content: 65.02

Gene sequence:

>669_bases
ATGACCCGGCTGGTGCTCGGGTCCGCCTCCCCTGGCCGGCTCAAAGTCCTTCGTGATGCCGGCATTGAGCCGCTGGTCAT
CGCCTCGCACGTCGACGAGGATGTCGTCATCGCGGCGCTGGGGCCGGACGCGGTCCCGAGCGATGTGGTGTGCGTACTGG
CCGCGGCAAAGGCCGCGCAGGTCGCGACCACGCTGACCGGAACGCAACGCATTGTGGCCGCGGATTGCGTTGTCGTTGCC
TGTGATTCGATGCTCTACATCGAAGGCAGGCTACTCGGCAAGCCAGCGTCAATCGACGAGGCGCGCGAGCAGTGGCGGTC
GATGGCGGGCCGGGCCGGCCAACTCTATACGGGCCACGGTGTTATCCGGTTGCAGGACAACAAAACCGTGTACCGTGCTG
CTGAAACAGCAATAACCACAGTATATTTCGGAACACCTTCGGCCTCCGATCTGGAGGCTTACCTGGCCAGTGGGGAGTCG
CTGCGGGTCGCGGGTGGATTCACCCTGGACGGTCTGGGCGGCTGGTTCATCGACGGCGTGCAGGGCAATCCGTCGAATGT
GATCGGCTTGAGCCTGCCGTTGCTGCGGTCGCTCGTGCAGCGATGCGGGCTGTCCGTCGCCGCACTGTGGGCAGGAAATG
CGGGCGGCCCAGCGCACAAGCAGCAGTAG

Upstream 100 bases:

>100_bases
AACCCGAGCCCACCCGGTGGGGGCTGCCGGTCGACCAGTTGCGGTACCCCGTCTTCAGTTGGCAGCGCATCACACTGCAA
GAAATGACGCACATGCGCCG

Downstream 100 bases:

>100_bases
CTTCGGACTGGGCCAGGTCGCCAGCGGTAGGCTCGATGATGTGCCGCTTCCCGCAGACCCTAGCCCCACCTTGTCGGCCT
ACGCCCATCCCGAACGGCTC

Product: Maf-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 222; Mature: 221

Protein sequence:

>222_residues
MTRLVLGSASPGRLKVLRDAGIEPLVIASHVDEDVVIAALGPDAVPSDVVCVLAAAKAAQVATTLTGTQRIVAADCVVVA
CDSMLYIEGRLLGKPASIDEAREQWRSMAGRAGQLYTGHGVIRLQDNKTVYRAAETAITTVYFGTPSASDLEAYLASGES
LRVAGGFTLDGLGGWFIDGVQGNPSNVIGLSLPLLRSLVQRCGLSVAALWAGNAGGPAHKQQ

Sequences:

>Translated_222_residues
MTRLVLGSASPGRLKVLRDAGIEPLVIASHVDEDVVIAALGPDAVPSDVVCVLAAAKAAQVATTLTGTQRIVAADCVVVA
CDSMLYIEGRLLGKPASIDEAREQWRSMAGRAGQLYTGHGVIRLQDNKTVYRAAETAITTVYFGTPSASDLEAYLASGES
LRVAGGFTLDGLGGWFIDGVQGNPSNVIGLSLPLLRSLVQRCGLSVAALWAGNAGGPAHKQQ
>Mature_221_residues
TRLVLGSASPGRLKVLRDAGIEPLVIASHVDEDVVIAALGPDAVPSDVVCVLAAAKAAQVATTLTGTQRIVAADCVVVAC
DSMLYIEGRLLGKPASIDEAREQWRSMAGRAGQLYTGHGVIRLQDNKTVYRAAETAITTVYFGTPSASDLEAYLASGESL
RVAGGFTLDGLGGWFIDGVQGNPSNVIGLSLPLLRSLVQRCGLSVAALWAGNAGGPAHKQQ

Specific function: Unknown

COG id: COG0424

COG function: function code D; Nucleotide-binding protein implicated in inhibition of septum formation

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the maf family

Homologues:

Organism=Homo sapiens, GI117553627, Length=193, Percent_Identity=31.6062176165803, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI291045183, Length=193, Percent_Identity=29.5336787564767, Blast_Score=72, Evalue=5e-13,
Organism=Escherichia coli, GI1789646, Length=193, Percent_Identity=30.5699481865285, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI87081830, Length=204, Percent_Identity=26.9607843137255, Blast_Score=70, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI193202443, Length=195, Percent_Identity=27.6923076923077, Blast_Score=90, Evalue=8e-19,
Organism=Drosophila melanogaster, GI78706856, Length=190, Percent_Identity=26.3157894736842, Blast_Score=65, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y3282_MYCTU (P96887)

Other databases:

- EMBL:   BX842582
- EMBL:   AE000516
- PIR:   C70980
- RefSeq:   NP_217799.1
- RefSeq:   NP_337910.1
- ProteinModelPortal:   P96887
- SMR:   P96887
- EnsemblBacteria:   EBMYCT00000000689
- EnsemblBacteria:   EBMYCT00000072541
- GeneID:   888718
- GeneID:   922479
- GenomeReviews:   AE000516_GR
- GenomeReviews:   AL123456_GR
- KEGG:   mtc:MT3381
- KEGG:   mtu:Rv3282
- TIGR:   MT3381
- TubercuList:   Rv3282
- GeneTree:   EBGT00050000015014
- HOGENOM:   HBG414045
- OMA:   VVGCDSM
- ProtClustDB:   PRK00148
- GO:   GO:0005737
- HAMAP:   MF_00528
- InterPro:   IPR003697
- PIRSF:   PIRSF006305
- TIGRFAMs:   TIGR00172

Pfam domain/function: PF02545 Maf

EC number: NA

Molecular weight: Translated: 23011; Mature: 22879

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: NA

Important sites: ACT_SITE 33-33

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRLVLGSASPGRLKVLRDAGIEPLVIASHVDEDVVIAALGPDAVPSDVVCVLAAAKAAQ
CCEEEEECCCCCEEEEEECCCCCEEEEEECCCCCEEEEEECCCCCCHHHHHHHHHHHHHH
VATTLTGTQRIVAADCVVVACDSMLYIEGRLLGKPASIDEAREQWRSMAGRAGQLYTGHG
HHHHHCCCCHHHHHHEEEEECCCEEEEEEEEECCCCCHHHHHHHHHHHHCCCCEEEECCE
VIRLQDNKTVYRAAETAITTVYFGTPSASDLEAYLASGESLRVAGGFTLDGLGGWFIDGV
EEEEECCCEEEHHHHCEEEEEEECCCCCHHHHHHHHCCCEEEEECCEEECCCCCEEEECC
QGNPSNVIGLSLPLLRSLVQRCGLSVAALWAGNAGGPAHKQQ
CCCCCCEEEECHHHHHHHHHHCCCEEEEEEECCCCCCCCCCC
>Mature Secondary Structure 
TRLVLGSASPGRLKVLRDAGIEPLVIASHVDEDVVIAALGPDAVPSDVVCVLAAAKAAQ
CEEEEECCCCCEEEEEECCCCCEEEEEECCCCCEEEEEECCCCCCHHHHHHHHHHHHHH
VATTLTGTQRIVAADCVVVACDSMLYIEGRLLGKPASIDEAREQWRSMAGRAGQLYTGHG
HHHHHCCCCHHHHHHEEEEECCCEEEEEEEEECCCCCHHHHHHHHHHHHCCCCEEEECCE
VIRLQDNKTVYRAAETAITTVYFGTPSASDLEAYLASGESLRVAGGFTLDGLGGWFIDGV
EEEEECCCEEEHHHHCEEEEEEECCCCCHHHHHHHHCCCEEEEECCEEECCCCCEEEECC
QGNPSNVIGLSLPLLRSLVQRCGLSVAALWAGNAGGPAHKQQ
CCCCCCEEEECHHHHHHHHHHCCCEEEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036