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The map label for this gene is ydeP [C]

Identifier: 148824089

GI number: 148824089

Start: 3220935

End: 3223274

Strand: Reverse

Name: ydeP [C]

Synonym: TBFG_12914

Alternate gene names: 148824089

Gene position: 3223274-3220935 (Counterclockwise)

Preceding gene: 148824090

Following gene: 148824088

Centisome position: 72.85

GC content: 65.47

Gene sequence:

>2340_bases
ATGTACGTTGAGGCGGTGAGGTGGCAGCGGTCGGCGGCGTCTCGCGACGTCCTCGCCGACTATGACGAGCAGGCGGTAAC
GGTGGCGCCGCGCAAACGCGAGGCCGCGGGCGTGCGGGCGGTGATGGTATCGCTGCAGCGGGGGATGCAGCAGATGGGCG
CGCTGCGCACCGCGGCGGCGCTGGCTCGGTTGAATCAGCGTAACGGCTTCGACTGCCCAGGCTGCGCGTGGCCGGAGGAG
CCCGGCGGACGCAAGCTGGCCGAGTTCTGCGAGAACGGCGCCAAGGCAGTCGCCGAAGAGGCCACCAAGCGTACCGTCAC
TGCGGAGTTCTTCGCTCGGCACTCGGTGGCGGAGCTGTCCGCGAAGCCCGAATATTGGCTGTCCCAGCAAGGCCGGCTCG
CCCACCCGATGGTCTTGCGCCCCGGTGATGACCACTACCGGCCCATCAGCTGGGATGCCGCTTATCAGCTGATCGCCGAG
CAGCTCAACGGGTTGGACAGTCCCGACCGGGCCGTGTTCTACACATCGGGGCGCACCAGCAACGAAGCGGCGTTCTGTTA
CCAGCTGCTCGTGCGCTCTTTCGGCACCAACAACCTGCCCGACTGCTCCAACATGTGCCACGAGTCCTCGGGTGCGGCGC
TGACCGACTCGATCGGAATCGGAAAAGGCTCGGTGACCATCGGTGACGTCGAGCACGCCGACCTGATCGTGATCGCCGGA
CAAAACCCCGGTACCAATCATCCCCGCATGCTGTCGGTGCTGGGGAAAGCGAAGGCCAACGGCGCCAAGATCATCGCCGT
GAACCCGCTGCCCGAGGCCGGGTTGATTCGGTTCAAAGATCCGCAGAAGGTGAACGGGGTTGTGGGACATGGTATCCCGA
TCGCCGACGAGTTCGTGCAGATCCGCCTCGGCGGGGACATGGCATTGTTCGCCGGGTTAGGCAGGTTGTTGTTGGAGGCC
GAGGAGAGGGTCCCCGGCAGCGTTGTCGACCGGTCGTTCGTCGACAACCATTGTGCCGGATTCGACGGGTACCGCCGCCG
GACTCTGCAGGTCGGCTTGGACACCGTGATGGACGCCACCGGCATCGAACTCGCGCAACTTCAGCGGGTCGCCGCGATGT
TGATGGCGTCGCAGCGCACGGTCATCTGCTGGGCTATGGGCTTGACCCAACACGCCCACGCCGTGGCCACCATCGGTGAG
GTCACCAACGTGCTGCTGCTGCGGGGCATGATCGGCAAACCCGGCGCGGGGGTGTGCCCGGTGCGCGGGCATTCCAACGT
ACAAGGGGACCGCACGATGGGGATCTGGGAGAAGATGCCCGAGCAGTTCCTGGCGGCGCTGGATCGTGAGTTCGGCATTA
CCAGCCCCCGAGCGCACGGCTTTGACACCGTGGCCGCAATCCGGGCCATGCGCGACGGTCGGGTCAGCGTCTTCATGGGC
ATGGGCGGAAACTTCGCGTCGGCCACCCCCGACACCGCCGTCACCGAGGCGGCCTTGCGCAGGTGCGCGCTGACTGTGCA
AGTCTCGACCAAGCTCAACCGCAGCCACCTTGTCCACGGCGCCACCGCGCTGATCCTGCCGACGCTGGGTCGGACCGATC
GCGATACCCGCAATGGTCGCAAACAATTGGTGTCGGTTGAGGATTCGATGTCGATGGTGCATCTGTCGCGTGGTAGCCTG
CACCCGCCCAGCGATCAGGTGCGCAGCGAGGTGCAGATCATCTGCCAGCTGGCCCGCGCCTTGTTCGGCCCCGGACATCC
GGTGCCATGGGAACGGTTCGCAGATGACTACGACACCATCCGTGACGCCATCGCCGCGGTGGTGCCCGGCTGTGACGACT
ACAACCACAAGGTGCGTGTGCCCGACGGATTCCAATTGCCGCACCCGCCGCGCGATGCGCGCGAATTCCGTACCAGCACA
GGCAAAGCTAACTTCGCGGTCAATCCGTTGCAGTGGGTGCCGGTGCCGCCCGGCCGGCTGGTGCTACAGACCCTACGCAG
CCATGACCAGTACAACACCACGATCTACGGGCTCGACGACCGATATCGCGGCGTGAAGGGCGGACGCCGGGTGGTGTTCA
TCAACCCGGCCGACATCGAAACGTTCGGTTTGACGGCGGGTGACCGTGTCGACCTGGTGTCGGAGTGGACCGACGGCCAA
GGCGGTCTGCAAGAACGGCGGGCAAAAGACTTTCTGGTGGTGGCATATTCGACGCCGGTCGGCAATGCTGCGGCCTACTA
CCCGGAGACCAATCCGCTGGTTCCGCTCGACCATACCGCGGCCCAATCGAACACCCCGGTGTCGAAGGCGATCATCGTGC
GATTGGAGCCAACGGCCTAG

Upstream 100 bases:

>100_bases
CATCGAGGAAGTCGAAAAACCCGAGCTGCGCCTGCCGGAATAGCTGCCCCAAGCGCCGTCACACGTCAATCGGCTGTGTG
CGGCAGTCGGTCGGTCGTGG

Downstream 100 bases:

>100_bases
TGGGGTACGCAACGGCGCATCGGCGGGTCAGGCATCTCAGCGCCGATCAGGTGATCACCCGGCCGGAAACCTTGGCCGTC
GAGGAGCCGCTGGAGATCCG

Product: formate dehydrogenase H fdhF

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 779; Mature: 779

Protein sequence:

>779_residues
MYVEAVRWQRSAASRDVLADYDEQAVTVAPRKREAAGVRAVMVSLQRGMQQMGALRTAAALARLNQRNGFDCPGCAWPEE
PGGRKLAEFCENGAKAVAEEATKRTVTAEFFARHSVAELSAKPEYWLSQQGRLAHPMVLRPGDDHYRPISWDAAYQLIAE
QLNGLDSPDRAVFYTSGRTSNEAAFCYQLLVRSFGTNNLPDCSNMCHESSGAALTDSIGIGKGSVTIGDVEHADLIVIAG
QNPGTNHPRMLSVLGKAKANGAKIIAVNPLPEAGLIRFKDPQKVNGVVGHGIPIADEFVQIRLGGDMALFAGLGRLLLEA
EERVPGSVVDRSFVDNHCAGFDGYRRRTLQVGLDTVMDATGIELAQLQRVAAMLMASQRTVICWAMGLTQHAHAVATIGE
VTNVLLLRGMIGKPGAGVCPVRGHSNVQGDRTMGIWEKMPEQFLAALDREFGITSPRAHGFDTVAAIRAMRDGRVSVFMG
MGGNFASATPDTAVTEAALRRCALTVQVSTKLNRSHLVHGATALILPTLGRTDRDTRNGRKQLVSVEDSMSMVHLSRGSL
HPPSDQVRSEVQIICQLARALFGPGHPVPWERFADDYDTIRDAIAAVVPGCDDYNHKVRVPDGFQLPHPPRDAREFRTST
GKANFAVNPLQWVPVPPGRLVLQTLRSHDQYNTTIYGLDDRYRGVKGGRRVVFINPADIETFGLTAGDRVDLVSEWTDGQ
GGLQERRAKDFLVVAYSTPVGNAAAYYPETNPLVPLDHTAAQSNTPVSKAIIVRLEPTA

Sequences:

>Translated_779_residues
MYVEAVRWQRSAASRDVLADYDEQAVTVAPRKREAAGVRAVMVSLQRGMQQMGALRTAAALARLNQRNGFDCPGCAWPEE
PGGRKLAEFCENGAKAVAEEATKRTVTAEFFARHSVAELSAKPEYWLSQQGRLAHPMVLRPGDDHYRPISWDAAYQLIAE
QLNGLDSPDRAVFYTSGRTSNEAAFCYQLLVRSFGTNNLPDCSNMCHESSGAALTDSIGIGKGSVTIGDVEHADLIVIAG
QNPGTNHPRMLSVLGKAKANGAKIIAVNPLPEAGLIRFKDPQKVNGVVGHGIPIADEFVQIRLGGDMALFAGLGRLLLEA
EERVPGSVVDRSFVDNHCAGFDGYRRRTLQVGLDTVMDATGIELAQLQRVAAMLMASQRTVICWAMGLTQHAHAVATIGE
VTNVLLLRGMIGKPGAGVCPVRGHSNVQGDRTMGIWEKMPEQFLAALDREFGITSPRAHGFDTVAAIRAMRDGRVSVFMG
MGGNFASATPDTAVTEAALRRCALTVQVSTKLNRSHLVHGATALILPTLGRTDRDTRNGRKQLVSVEDSMSMVHLSRGSL
HPPSDQVRSEVQIICQLARALFGPGHPVPWERFADDYDTIRDAIAAVVPGCDDYNHKVRVPDGFQLPHPPRDAREFRTST
GKANFAVNPLQWVPVPPGRLVLQTLRSHDQYNTTIYGLDDRYRGVKGGRRVVFINPADIETFGLTAGDRVDLVSEWTDGQ
GGLQERRAKDFLVVAYSTPVGNAAAYYPETNPLVPLDHTAAQSNTPVSKAIIVRLEPTA
>Mature_779_residues
MYVEAVRWQRSAASRDVLADYDEQAVTVAPRKREAAGVRAVMVSLQRGMQQMGALRTAAALARLNQRNGFDCPGCAWPEE
PGGRKLAEFCENGAKAVAEEATKRTVTAEFFARHSVAELSAKPEYWLSQQGRLAHPMVLRPGDDHYRPISWDAAYQLIAE
QLNGLDSPDRAVFYTSGRTSNEAAFCYQLLVRSFGTNNLPDCSNMCHESSGAALTDSIGIGKGSVTIGDVEHADLIVIAG
QNPGTNHPRMLSVLGKAKANGAKIIAVNPLPEAGLIRFKDPQKVNGVVGHGIPIADEFVQIRLGGDMALFAGLGRLLLEA
EERVPGSVVDRSFVDNHCAGFDGYRRRTLQVGLDTVMDATGIELAQLQRVAAMLMASQRTVICWAMGLTQHAHAVATIGE
VTNVLLLRGMIGKPGAGVCPVRGHSNVQGDRTMGIWEKMPEQFLAALDREFGITSPRAHGFDTVAAIRAMRDGRVSVFMG
MGGNFASATPDTAVTEAALRRCALTVQVSTKLNRSHLVHGATALILPTLGRTDRDTRNGRKQLVSVEDSMSMVHLSRGSL
HPPSDQVRSEVQIICQLARALFGPGHPVPWERFADDYDTIRDAIAAVVPGCDDYNHKVRVPDGFQLPHPPRDAREFRTST
GKANFAVNPLQWVPVPPGRLVLQTLRSHDQYNTTIYGLDDRYRGVKGGRRVVFINPADIETFGLTAGDRVDLVSEWTDGQ
GGLQERRAKDFLVVAYSTPVGNAAAYYPETNPLVPLDHTAAQSNTPVSKAIIVRLEPTA

Specific function: Unknown

COG id: COG0243

COG function: function code C; Anaerobic dehydrogenases, typically selenocysteine-containing

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family

Homologues:

Organism=Escherichia coli, GI1787778, Length=737, Percent_Identity=43.4192672998643, Blast_Score=604, Evalue=1e-174,
Organism=Escherichia coli, GI3868721, Length=368, Percent_Identity=31.25, Blast_Score=166, Evalue=7e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y2900_MYCTU (P65408)

Other databases:

- EMBL:   BX842581
- EMBL:   AE000516
- PIR:   G70926
- RefSeq:   NP_217416.1
- RefSeq:   NP_337480.1
- ProteinModelPortal:   P65408
- EnsemblBacteria:   EBMYCT00000002461
- EnsemblBacteria:   EBMYCT00000071630
- GeneID:   887987
- GeneID:   925310
- GenomeReviews:   AE000516_GR
- GenomeReviews:   AL123456_GR
- KEGG:   mtc:MT2968
- KEGG:   mtu:Rv2900c
- TIGR:   MT2968
- TubercuList:   Rv2900c
- GeneTree:   EBGT00050000015817
- HOGENOM:   HBG638124
- OMA:   VYGQRRV
- ProtClustDB:   CLSK792150
- InterPro:   IPR009010
- InterPro:   IPR006657
- InterPro:   IPR006656
- InterPro:   IPR010046
- Gene3D:   G3DSA:2.40.40.20
- TIGRFAMs:   TIGR01701

Pfam domain/function: PF00384 Molybdopterin; PF01568 Molydop_binding; SSF50692 Asp_decarb_fold

EC number: NA

Molecular weight: Translated: 84567; Mature: 84567

Theoretical pI: Translated: 7.77; Mature: 7.77

Prosite motif: PS00075 DHFR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYVEAVRWQRSAASRDVLADYDEQAVTVAPRKREAAGVRAVMVSLQRGMQQMGALRTAAA
CCCCHHHHHHHHCCCCHHHCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LARLNQRNGFDCPGCAWPEEPGGRKLAEFCENGAKAVAEEATKRTVTAEFFARHSVAELS
HHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
AKPEYWLSQQGRLAHPMVLRPGDDHYRPISWDAAYQLIAEQLNGLDSPDRAVFYTSGRTS
CCCCHHHCCCCCCCCCEEECCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCEEEEECCCCC
NEAAFCYQLLVRSFGTNNLPDCSNMCHESSGAALTDSIGIGKGSVTIGDVEHADLIVIAG
CHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCCEEECCCCCCCCCEEECCCCCCCEEEEEC
QNPGTNHPRMLSVLGKAKANGAKIIAVNPLPEAGLIRFKDPQKVNGVVGHGIPIADEFVQ
CCCCCCCCHHHHHHHHCCCCCCEEEEECCCCCCCEEEECCCCHHCCCCCCCCCCCCCEEE
IRLGGDMALFAGLGRLLLEAEERVPGSVVDRSFVDNHCAGFDGYRRRTLQVGLDTVMDAT
EEECCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCC
GIELAQLQRVAAMLMASQRTVICWAMGLTQHAHAVATIGEVTNVLLLRGMIGKPGAGVCP
CCHHHHHHHHHHHHHHCCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
VRGHSNVQGDRTMGIWEKMPEQFLAALDREFGITSPRAHGFDTVAAIRAMRDGRVSVFMG
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCEEEEEE
MGGNFASATPDTAVTEAALRRCALTVQVSTKLNRSHLVHGATALILPTLGRTDRDTRNGR
CCCCCCCCCCCHHHHHHHHHHHEEEEEEECCCCCHHHHHCCCEEEEECCCCCCCCHHCCH
KQLVSVEDSMSMVHLSRGSLHPPSDQVRSEVQIICQLARALFGPGHPVPWERFADDYDTI
HHEEEHHHHHHEEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCHHHHH
RDAIAAVVPGCDDYNHKVRVPDGFQLPHPPRDAREFRTSTGKANFAVNPLQWVPVPPGRL
HHHHHHHCCCCCCCCCEEECCCCCCCCCCCCHHHHHHHCCCCCCEEECCEEEECCCCHHH
VLQTLRSHDQYNTTIYGLDDRYRGVKGGRRVVFINPADIETFGLTAGDRVDLVSEWTDGQ
HHHHHHCCCCCCCEEEECCHHHCCCCCCCEEEEEECCCCEEECCCCCCCCHHHHCCCCCC
GGLQERRAKDFLVVAYSTPVGNAAAYYPETNPLVPLDHTAAQSNTPVSKAIIVRLEPTA
CCHHHHCCCCEEEEEEECCCCCCEEECCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCC
>Mature Secondary Structure
MYVEAVRWQRSAASRDVLADYDEQAVTVAPRKREAAGVRAVMVSLQRGMQQMGALRTAAA
CCCCHHHHHHHHCCCCHHHCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LARLNQRNGFDCPGCAWPEEPGGRKLAEFCENGAKAVAEEATKRTVTAEFFARHSVAELS
HHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
AKPEYWLSQQGRLAHPMVLRPGDDHYRPISWDAAYQLIAEQLNGLDSPDRAVFYTSGRTS
CCCCHHHCCCCCCCCCEEECCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCEEEEECCCCC
NEAAFCYQLLVRSFGTNNLPDCSNMCHESSGAALTDSIGIGKGSVTIGDVEHADLIVIAG
CHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCCEEECCCCCCCCCEEECCCCCCCEEEEEC
QNPGTNHPRMLSVLGKAKANGAKIIAVNPLPEAGLIRFKDPQKVNGVVGHGIPIADEFVQ
CCCCCCCCHHHHHHHHCCCCCCEEEEECCCCCCCEEEECCCCHHCCCCCCCCCCCCCEEE
IRLGGDMALFAGLGRLLLEAEERVPGSVVDRSFVDNHCAGFDGYRRRTLQVGLDTVMDAT
EEECCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCC
GIELAQLQRVAAMLMASQRTVICWAMGLTQHAHAVATIGEVTNVLLLRGMIGKPGAGVCP
CCHHHHHHHHHHHHHHCCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
VRGHSNVQGDRTMGIWEKMPEQFLAALDREFGITSPRAHGFDTVAAIRAMRDGRVSVFMG
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCEEEEEE
MGGNFASATPDTAVTEAALRRCALTVQVSTKLNRSHLVHGATALILPTLGRTDRDTRNGR
CCCCCCCCCCCHHHHHHHHHHHEEEEEEECCCCCHHHHHCCCEEEEECCCCCCCCHHCCH
KQLVSVEDSMSMVHLSRGSLHPPSDQVRSEVQIICQLARALFGPGHPVPWERFADDYDTI
HHEEEHHHHHHEEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCHHHHH
RDAIAAVVPGCDDYNHKVRVPDGFQLPHPPRDAREFRTSTGKANFAVNPLQWVPVPPGRL
HHHHHHHCCCCCCCCCEEECCCCCCCCCCCCHHHHHHHCCCCCCEEECCEEEECCCCHHH
VLQTLRSHDQYNTTIYGLDDRYRGVKGGRRVVFINPADIETFGLTAGDRVDLVSEWTDGQ
HHHHHHCCCCCCCEEEECCHHHCCCCCCCEEEEEECCCCEEECCCCCCCCHHHHCCCCCC
GGLQERRAKDFLVVAYSTPVGNAAAYYPETNPLVPLDHTAAQSNTPVSKAIIVRLEPTA
CCHHHHCCCCEEEEEEECCCCCCEEECCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036