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The map label for this gene is ppe44

Identifier: 148823958

GI number: 148823958

Start: 3091264

End: 3092412

Strand: Reverse

Name: ppe44

Synonym: TBFG_12783

Alternate gene names: 148823958

Gene position: 3092412-3091264 (Counterclockwise)

Preceding gene: 148823959

Following gene: 148823957

Centisome position: 69.89

GC content: 66.49

Gene sequence:

>1149_bases
GTGGATTTTGGAGCTCTACCTCCGGAGGTCAATTCTGCGCGCATGTATGGCGGCGCGGGCGCGGCAGACCTGCTGGCGGC
TGCGGCTGCGTGGAACGGCATAGCTGTCGAGGTGAGCACAGCTGCGTCCTCCGTCGGGTCGGTCATCACGCGGCTGAGCA
CCGAGCACTGGATGGGTCCCGCATCGTTGTCGATGGCCGCCGCGGTGCAGCCCTATTTGGTCTGGTTGACCTGCACCGCT
GAATCCTCGGCGCTCGCGGCGGCACAGGCCATGGCGTCTGCGGCCGCCTTTGAAACGGCGTTTGCGCTGACAGTGCCCCC
GGCCGAGGTGGTTGCCAACAGAGCCCTGTTGGCTGAACTGACAGCGACCAACATCCTTGGGCAAAACGTGTCGGCCATCG
CGGCTACCGAGGCACGCTATGGCGAAATGTGGGCCCAAGACGCTTCGGCCATGTACGGCTATGCGGCCGCATCCGCGGTC
GCCGCAAGACTGAACCCGCTGACCAGGCCGTCGCACATCACCAATCCGGCCGGGCTCGCACACCAAGCCGCCGCTGTTGG
CCAAGCCGGCGCATCCGCTTTCGCGCGCCAGGTGGGTCTGAGCCACCTGATCAGCGACGTCGCCGACGCTGTCCTGAGCT
TCGCCTCCCCGGTGATGTCCGCGGCCGATACCGGGTTGGAGGCGGTCAGGCAGTTCCTCAATCTCGATGTTCCGCTGTTC
GTAGAATCCGCGTTTCACGGCCTGGGTGGCGTGGCAGACTTTGCCACGGCCGCCATTGGCAATATGACGCTTCTTGCCGA
TGCTATGGGAACCGTTGGCGGAGCCGCTCCAGGTGGCGGCGCGGCAGCCGCGGTGGCACACGCGGTTGCCCCAGCGGGCG
TCGGCGGAACAGCGCTGACCGCCGATTTGGGCAATGCGTCCGTGGTTGGTCGCCTGTCGGTGCCGGCAAGCTGGTCTACT
GCAGCGCCGGCGACGGCAGCCGGCGCGGCCTTGGATGGCACAGGCTGGGCAGTTCCCGAGGAGGACGGCCCGATCGCAGT
GATGCCGCCTGCCCCTGGAATGGTCGTAGCCGCCAACAGTGTTGGTGCCGACTCCGGACCACGGTACGGAGTCAAGCCGA
TTGTTATGCCCAAGCACGGCCTCTTCTGA

Upstream 100 bases:

>100_bases
CGAGCGTGGTGCCTACGCTGGCGCTGACCTTGATGGAATAATGGCTGCCTCAGACGGAGCACCGGCCACCACTGCACTCG
ACCAGAAACGGAACGCCTCA

Downstream 100 bases:

>100_bases
TCTGGAGACACCGAGACAAGCGCACGCGGCCGACCAGCGCGCCGCCGCGGCCACATTGCGCTAACCCTCCCGCGGCGCGT
GTTTCATTTCGCTGCTGCGG

Product: PPE family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 382; Mature: 382

Protein sequence:

>382_residues
MDFGALPPEVNSARMYGGAGAADLLAAAAAWNGIAVEVSTAASSVGSVITRLSTEHWMGPASLSMAAAVQPYLVWLTCTA
ESSALAAAQAMASAAAFETAFALTVPPAEVVANRALLAELTATNILGQNVSAIAATEARYGEMWAQDASAMYGYAAASAV
AARLNPLTRPSHITNPAGLAHQAAAVGQAGASAFARQVGLSHLISDVADAVLSFASPVMSAADTGLEAVRQFLNLDVPLF
VESAFHGLGGVADFATAAIGNMTLLADAMGTVGGAAPGGGAAAAVAHAVAPAGVGGTALTADLGNASVVGRLSVPASWST
AAPATAAGAALDGTGWAVPEEDGPIAVMPPAPGMVVAANSVGADSGPRYGVKPIVMPKHGLF

Sequences:

>Translated_382_residues
MDFGALPPEVNSARMYGGAGAADLLAAAAAWNGIAVEVSTAASSVGSVITRLSTEHWMGPASLSMAAAVQPYLVWLTCTA
ESSALAAAQAMASAAAFETAFALTVPPAEVVANRALLAELTATNILGQNVSAIAATEARYGEMWAQDASAMYGYAAASAV
AARLNPLTRPSHITNPAGLAHQAAAVGQAGASAFARQVGLSHLISDVADAVLSFASPVMSAADTGLEAVRQFLNLDVPLF
VESAFHGLGGVADFATAAIGNMTLLADAMGTVGGAAPGGGAAAAVAHAVAPAGVGGTALTADLGNASVVGRLSVPASWST
AAPATAAGAALDGTGWAVPEEDGPIAVMPPAPGMVVAANSVGADSGPRYGVKPIVMPKHGLF
>Mature_382_residues
MDFGALPPEVNSARMYGGAGAADLLAAAAAWNGIAVEVSTAASSVGSVITRLSTEHWMGPASLSMAAAVQPYLVWLTCTA
ESSALAAAQAMASAAAFETAFALTVPPAEVVANRALLAELTATNILGQNVSAIAATEARYGEMWAQDASAMYGYAAASAV
AARLNPLTRPSHITNPAGLAHQAAAVGQAGASAFARQVGLSHLISDVADAVLSFASPVMSAADTGLEAVRQFLNLDVPLF
VESAFHGLGGVADFATAAIGNMTLLADAMGTVGGAAPGGGAAAAVAHAVAPAGVGGTALTADLGNASVVGRLSVPASWST
AAPATAAGAALDGTGWAVPEEDGPIAVMPPAPGMVVAANSVGADSGPRYGVKPIVMPKHGLF

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mycobacterial PPE family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PPE44_MYCTU (Q79FA7)

Other databases:

- EMBL:   BX842580
- EMBL:   AE000516
- PIR:   A70882
- RefSeq:   NP_337345.1
- RefSeq:   YP_177677.1
- HSSP:   Q79FE1
- ProteinModelPortal:   Q79FA7
- SMR:   Q79FA7
- EnsemblBacteria:   EBMYCT00000002788
- EnsemblBacteria:   EBMYCT00000072058
- GeneID:   888456
- GeneID:   925439
- GenomeReviews:   AE000516_GR
- GenomeReviews:   AL123456_GR
- KEGG:   mtc:MT2840
- KEGG:   mtu:Rv2770c
- TIGR:   MT2840
- TubercuList:   Rv2770c
- GeneTree:   EBGT00050000014887
- HOGENOM:   HBG572308
- OMA:   WNDIAVE
- ProtClustDB:   CLSK799766
- InterPro:   IPR022171
- InterPro:   IPR000030

Pfam domain/function: PF12484 PE_PPE_C; PF00823 PPE

EC number: NA

Molecular weight: Translated: 37468; Mature: 37468

Theoretical pI: Translated: 4.44; Mature: 4.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDFGALPPEVNSARMYGGAGAADLLAAAAAWNGIAVEVSTAASSVGSVITRLSTEHWMGP
CCCCCCCCCCCCCEEECCCCHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHHHCCCH
ASLSMAAAVQPYLVWLTCTAESSALAAAQAMASAAAFETAFALTVPPAEVVANRALLAEL
HHHHHHHHCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHEEEEECCHHHHHHHHHHHHHH
TATNILGQNVSAIAATEARYGEMWAQDASAMYGYAAASAVAARLNPLTRPSHITNPAGLA
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHH
HQAAAVGQAGASAFARQVGLSHLISDVADAVLSFASPVMSAADTGLEAVRQFLNLDVPLF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
VESAFHGLGGVADFATAAIGNMTLLADAMGTVGGAAPGGGAAAAVAHAVAPAGVGGTALT
HHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCEEE
ADLGNASVVGRLSVPASWSTAAPATAAGAALDGTGWAVPEEDGPIAVMPPAPGMVVAANS
ECCCCCEEEEEEECCCCCCCCCCCHHCCCCCCCCCCCCCCCCCCEEEECCCCCEEEEECC
VGADSGPRYGVKPIVMPKHGLF
CCCCCCCCCCCCCEECCCCCCC
>Mature Secondary Structure
MDFGALPPEVNSARMYGGAGAADLLAAAAAWNGIAVEVSTAASSVGSVITRLSTEHWMGP
CCCCCCCCCCCCCEEECCCCHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHHHCCCH
ASLSMAAAVQPYLVWLTCTAESSALAAAQAMASAAAFETAFALTVPPAEVVANRALLAEL
HHHHHHHHCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHEEEEECCHHHHHHHHHHHHHH
TATNILGQNVSAIAATEARYGEMWAQDASAMYGYAAASAVAARLNPLTRPSHITNPAGLA
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHH
HQAAAVGQAGASAFARQVGLSHLISDVADAVLSFASPVMSAADTGLEAVRQFLNLDVPLF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
VESAFHGLGGVADFATAAIGNMTLLADAMGTVGGAAPGGGAAAAVAHAVAPAGVGGTALT
HHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCEEE
ADLGNASVVGRLSVPASWSTAAPATAAGAALDGTGWAVPEEDGPIAVMPPAPGMVVAANS
ECCCCCEEEEEEECCCCCCCCCCCHHCCCCCCCCCCCCCCCCCCEEEECCCCCEEEEECC
VGADSGPRYGVKPIVMPKHGLF
CCCCCCCCCCCCCEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036