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The map label for this gene is 148823906

Identifier: 148823906

GI number: 148823906

Start: 3041822

End: 3042316

Strand: Reverse

Name: 148823906

Synonym: TBFG_12731

Alternate gene names: NA

Gene position: 3042316-3041822 (Counterclockwise)

Preceding gene: 148823907

Following gene: 148823901

Centisome position: 68.76

GC content: 62.42

Gene sequence:

>495_bases
ATGACCCGAGATCTGGCCCCTGCCCTGCAGGCGCTGTCACCCCTCCTGGGGAGTTGGGCGGGTCGCGGTGCGGGCAAGTA
CCCCACCATCCGGCCGTTCGAATACCTCGAGGAAGTCGTATTCGCCCATGTGGGTAAACCGTTTCTGACGTACACACAGC
AGACCAGGGCGGTAGCTGACGGGAAGCCGCTGCATTCCGAGACGGGGTATCTCCGCGTTTGCCGACCGGGCTGCGTTGAA
CTCGTTCTCGCCCATCCAAGCGGCATCACCGAAATTGAGGTTGGAACCTATTCGGTGACCGGTGACGTCATCGAACTCGA
ATTGTCCACACGCGCGGATGGGTCGATCGGATTGGCCCCGACCGCAAAAGAGGTGACCGCCCTTGACCGTTCCTACCGCA
TCGACGGCGACGAGCTTTCGTACTCGTTGCAGATGCGCGCGGTCGGGCAACCCCTGCAGGATCACCTTGCCGCCGTGTTG
CATCGGCAGCGCTGA

Upstream 100 bases:

>100_bases
CGAGATTGAGGCGCTTCGCGCGCACCGCAACCTATCAGCCCACAGCTGACCGATCTCGCGGCGCTAGGCTTCCCGCATGC
CTGTCCCCCGCAAGCGGGCG

Downstream 100 bases:

>100_bases
GCTCTACGTCAGTCGAGTTGTGCCACACCGTCGCTGACAACTCGGCCGGCTACCCGAACCCAGCCCTCGGGACTCCAGGT
GGTGTGGATCAACGATCCTT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 164; Mature: 163

Protein sequence:

>164_residues
MTRDLAPALQALSPLLGSWAGRGAGKYPTIRPFEYLEEVVFAHVGKPFLTYTQQTRAVADGKPLHSETGYLRVCRPGCVE
LVLAHPSGITEIEVGTYSVTGDVIELELSTRADGSIGLAPTAKEVTALDRSYRIDGDELSYSLQMRAVGQPLQDHLAAVL
HRQR

Sequences:

>Translated_164_residues
MTRDLAPALQALSPLLGSWAGRGAGKYPTIRPFEYLEEVVFAHVGKPFLTYTQQTRAVADGKPLHSETGYLRVCRPGCVE
LVLAHPSGITEIEVGTYSVTGDVIELELSTRADGSIGLAPTAKEVTALDRSYRIDGDELSYSLQMRAVGQPLQDHLAAVL
HRQR
>Mature_163_residues
TRDLAPALQALSPLLGSWAGRGAGKYPTIRPFEYLEEVVFAHVGKPFLTYTQQTRAVADGKPLHSETGYLRVCRPGCVEL
VLAHPSGITEIEVGTYSVTGDVIELELSTRADGSIGLAPTAKEVTALDRSYRIDGDELSYSLQMRAVGQPLQDHLAAVLH
RQR

Specific function: May play a role in the intracellular transport of hydrophobic ligands (Potential)

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPF0678 family

Homologues:

Organism=Homo sapiens, GI256818827, Length=156, Percent_Identity=30.7692307692308, Blast_Score=79, Evalue=2e-15,
Organism=Homo sapiens, GI256818825, Length=155, Percent_Identity=30.3225806451613, Blast_Score=77, Evalue=6e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y2717_MYCTU (O07216)

Other databases:

- EMBL:   BX842580
- EMBL:   AE000516
- PIR:   H70532
- RefSeq:   NP_217233.1
- RefSeq:   NP_337292.1
- PDB:   2FR2
- PDBsum:   2FR2
- ProteinModelPortal:   O07216
- SMR:   O07216
- EnsemblBacteria:   EBMYCT00000000283
- EnsemblBacteria:   EBMYCT00000069574
- GeneID:   887284
- GeneID:   925510
- GenomeReviews:   AE000516_GR
- GenomeReviews:   AL123456_GR
- KEGG:   mtc:MT2790
- KEGG:   mtu:Rv2717c
- TIGR:   MT2790
- TubercuList:   Rv2717c
- GeneTree:   EBGT00050000017663
- HOGENOM:   HBG445899
- OMA:   IEVVIAQ
- ProtClustDB:   CLSK792029
- GO:   GO:0006810
- HAMAP:   MF_01297
- InterPro:   IPR011038
- InterPro:   IPR014878
- InterPro:   IPR022939

Pfam domain/function: PF08768 DUF1794; SSF50814 Calycin

EC number: NA

Molecular weight: Translated: 17847; Mature: 17715

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: NA

Important sites: BINDING 130-130

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRDLAPALQALSPLLGSWAGRGAGKYPTIRPFEYLEEVVFAHVGKPFLTYTQQTRAVAD
CCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHCC
GKPLHSETGYLRVCRPGCVELVLAHPSGITEIEVGTYSVTGDVIELELSTRADGSIGLAP
CCCCCCCCCEEEEECCCCEEEEEECCCCCCEEECCEEEECCCEEEEEECCCCCCCCCCCC
TAKEVTALDRSYRIDGDELSYSLQMRAVGQPLQDHLAAVLHRQR
CHHHHHHHHHHCCCCCHHHEEEEEEHHCCCCHHHHHHHHHHCCC
>Mature Secondary Structure 
TRDLAPALQALSPLLGSWAGRGAGKYPTIRPFEYLEEVVFAHVGKPFLTYTQQTRAVAD
CCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHCC
GKPLHSETGYLRVCRPGCVELVLAHPSGITEIEVGTYSVTGDVIELELSTRADGSIGLAP
CCCCCCCCCEEEEECCCCEEEEEECCCCCCEEECCEEEECCCEEEEEECCCCCCCCCCCC
TAKEVTALDRSYRIDGDELSYSLQMRAVGQPLQDHLAAVLHRQR
CHHHHHHHHHHCCCCCHHHEEEEEEHHCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036; 12368430