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The map label for this gene is rnd [H]

Identifier: 148823871

GI number: 148823871

Start: 3008694

End: 3010010

Strand: Direct

Name: rnd [H]

Synonym: TBFG_12696

Alternate gene names: 148823871

Gene position: 3008694-3010010 (Clockwise)

Preceding gene: 148823870

Following gene: 148823873

Centisome position: 68.0

GC content: 68.64

Gene sequence:

>1317_bases
ATGTGCCCCGAGCCGTCTCACGCGGGAGCTGCTGAGTCCGAAGGCACGGAATCGGAACCCACCCCCTTGCTCCGGCCCGC
CGGTGGGATACCGGATCTGTGTGTGACCGTCGGTGAAATCGCCGCTGCCGCAGAACTACTGGACCGCGGGCGCGGACCGT
TCGCGGTAGACGCCGAGCGGGCGTCGGGTTTCCGCTACTCCGGCCGCGCCTACCTGATTCAGATCCGGCGGGCCGAGGCC
GGCACCGTACTGATCGACCCGGTCAGCCACGGCGGTGACCCGTTGACCGTGCTGGCGCCGGTCGCCGAGGTGCTCAGCAC
CAACGAGTGGATCCTGCACTCCGCCGATCAGGATCTGCCCTGTCTCGCCGAGGTCGGTATGCGACCGCCAGCGCTATACG
ACACCGAGCTTGCCGGGCGCCTGGCCGGGTTCGATCGAGTGAACCTGGCGGCCATGGTCGAGCGGTTACTTGGACTGGGA
TTGACCAAGGGCCACGGCGCGGCCGACTGGTCCAAGCGCCCGCTACCCTCGGCCTGGCTGAACTACGCGGCGTTGGACGT
GGAACTGCTCATCGAACTACGCGCGGCGATCTCGCGGGTGCTGGCCGAGCAAGGCAAAACCGATTGGGCTGCGCAGGAAT
TCGAGCACCTGCGGTCGTTCGAATCAAGGCCACCCCCAGCGGCCGCCCGGCAGGACCGCTGGCGACGAACCTCGGGTATC
CACAAAGTGCATGACCGGCGGGGGCTGGCCGCGGTCCGCGAATTGTGGACAGCGCGTGACCGAATCGCCCAGCGCCGCGA
CATCGCGCCCCGCCGGATCTTGCCGGACTCGGCCATTATCGATGCCGCCATCGCCGACCCAAAGTCAGTCGACGACCTTG
TCGCGTTACCGGTGTTCGGCGGACGCAACCAACGTCGCAGCGCGGCTGTGTGGTGGGCGGCACTGGCAGCCGCACGCGAA
AGCCCAGATCCGCCGGAGATCGCCGAACCGGCAAACGGGCCGCCGCCGCCGGGGCGGTGGGTCAGACGGAAACCGGCAGC
CGCCGCACGGCTGGATGCGGCGCGCGCGGCGCTGACGGAGGTGTCGCAACGGGTGCGGGTACCGACCGAGAACCTGGTCT
CACCTGATCTGGTGCGACGGCTGTGTTGGGAATGGGAGGACATCTCGCAGAGTTCTCCAGACCCGATTGCCGCTGTCGAG
GCGTACCTGCGCACCGGCCAGGCACGGGCCTGGCAGCTCGAACTAGTGGTCCCCATCCTGACCGCGGCGTTGACAGGGGC
TCCGGACGCCGGCGCCCAGGGCGATGATGGCTCTTAG

Upstream 100 bases:

>100_bases
CTGGGCGCCCATGTCCAGGCGTTCTGCGACGTCCTGGAGCACGCGGCCGGCCTGCCGCCAGCCGGGGTCACCGACCTGGG
CTCGCGGTCACGCGCCTGAC

Downstream 100 bases:

>100_bases
TCGAGATGTTCTGGAATCGCGTCGGACGCACACACCCCGGTACCCAGCGCGGCGACCCAGCCGGTGATCCGCCGGGCCAC
GTCCTGGTCGGTAAGCCCCA

Product: hypothetical protein

Products: NA

Alternate protein names: RNase D [H]

Number of amino acids: Translated: 438; Mature: 438

Protein sequence:

>438_residues
MCPEPSHAGAAESEGTESEPTPLLRPAGGIPDLCVTVGEIAAAAELLDRGRGPFAVDAERASGFRYSGRAYLIQIRRAEA
GTVLIDPVSHGGDPLTVLAPVAEVLSTNEWILHSADQDLPCLAEVGMRPPALYDTELAGRLAGFDRVNLAAMVERLLGLG
LTKGHGAADWSKRPLPSAWLNYAALDVELLIELRAAISRVLAEQGKTDWAAQEFEHLRSFESRPPPAAARQDRWRRTSGI
HKVHDRRGLAAVRELWTARDRIAQRRDIAPRRILPDSAIIDAAIADPKSVDDLVALPVFGGRNQRRSAAVWWAALAAARE
SPDPPEIAEPANGPPPPGRWVRRKPAAAARLDAARAALTEVSQRVRVPTENLVSPDLVRRLCWEWEDISQSSPDPIAAVE
AYLRTGQARAWQLELVVPILTAALTGAPDAGAQGDDGS

Sequences:

>Translated_438_residues
MCPEPSHAGAAESEGTESEPTPLLRPAGGIPDLCVTVGEIAAAAELLDRGRGPFAVDAERASGFRYSGRAYLIQIRRAEA
GTVLIDPVSHGGDPLTVLAPVAEVLSTNEWILHSADQDLPCLAEVGMRPPALYDTELAGRLAGFDRVNLAAMVERLLGLG
LTKGHGAADWSKRPLPSAWLNYAALDVELLIELRAAISRVLAEQGKTDWAAQEFEHLRSFESRPPPAAARQDRWRRTSGI
HKVHDRRGLAAVRELWTARDRIAQRRDIAPRRILPDSAIIDAAIADPKSVDDLVALPVFGGRNQRRSAAVWWAALAAARE
SPDPPEIAEPANGPPPPGRWVRRKPAAAARLDAARAALTEVSQRVRVPTENLVSPDLVRRLCWEWEDISQSSPDPIAAVE
AYLRTGQARAWQLELVVPILTAALTGAPDAGAQGDDGS
>Mature_438_residues
MCPEPSHAGAAESEGTESEPTPLLRPAGGIPDLCVTVGEIAAAAELLDRGRGPFAVDAERASGFRYSGRAYLIQIRRAEA
GTVLIDPVSHGGDPLTVLAPVAEVLSTNEWILHSADQDLPCLAEVGMRPPALYDTELAGRLAGFDRVNLAAMVERLLGLG
LTKGHGAADWSKRPLPSAWLNYAALDVELLIELRAAISRVLAEQGKTDWAAQEFEHLRSFESRPPPAAARQDRWRRTSGI
HKVHDRRGLAAVRELWTARDRIAQRRDIAPRRILPDSAIIDAAIADPKSVDDLVALPVFGGRNQRRSAAVWWAALAAARE
SPDPPEIAEPANGPPPPGRWVRRKPAAAARLDAARAALTEVSQRVRVPTENLVSPDLVRRLCWEWEDISQSSPDPIAAVE
AYLRTGQARAWQLELVVPILTAALTGAPDAGAQGDDGS

Specific function: Cleaves multimeric tRNA precursor at the spacer region. Contribute to the 3' maturation of several stable RNAs [H]

COG id: COG0349

COG function: function code J; Ribonuclease D

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HRDC domain [H]

Homologues:

Organism=Escherichia coli, GI1788105, Length=338, Percent_Identity=25.4437869822485, Blast_Score=75, Evalue=9e-15,
Organism=Saccharomyces cerevisiae, GI6324574, Length=276, Percent_Identity=26.4492753623188, Blast_Score=65, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002562
- InterPro:   IPR002121
- InterPro:   IPR010997
- InterPro:   IPR006292
- InterPro:   IPR012337 [H]

Pfam domain/function: PF01612 3_5_exonuc; PF00570 HRDC [H]

EC number: =3.1.13.5 [H]

Molecular weight: Translated: 47225; Mature: 47225

Theoretical pI: Translated: 5.54; Mature: 5.54

Prosite motif: PS50967 HRDC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCPEPSHAGAAESEGTESEPTPLLRPAGGIPDLCVTVGEIAAAAELLDRGRGPFAVDAER
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEHHH
ASGFRYSGRAYLIQIRRAEAGTVLIDPVSHGGDPLTVLAPVAEVLSTNEWILHSADQDLP
CCCCEECCCEEEEEEEECCCCEEEECCCCCCCCCHHHHHHHHHHHCCCCEEEECCCCCCC
CLAEVGMRPPALYDTELAGRLAGFDRVNLAAMVERLLGLGLTKGHGAADWSKRPLPSAWL
HHHHCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHH
NYAALDVELLIELRAAISRVLAEQGKTDWAAQEFEHLRSFESRPPPAAARQDRWRRTSGI
HHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCH
HKVHDRRGLAAVRELWTARDRIAQRRDIAPRRILPDSAIIDAAIADPKSVDDLVALPVFG
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCCCCEEEECCCC
GRNQRRSAAVWWAALAAARESPDPPEIAEPANGPPPPGRWVRRKPAAAARLDAARAALTE
CCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHCCCCHHHHHHHHHHHHHHH
VSQRVRVPTENLVSPDLVRRLCWEWEDISQSSPDPIAAVEAYLRTGQARAWQLELVVPIL
HHHHHCCCHHHCCCHHHHHHHHHCHHHHCCCCCCHHHHHHHHHHCCCCCEEEEEHHHHHH
TAALTGAPDAGAQGDDGS
HHHHCCCCCCCCCCCCCC
>Mature Secondary Structure
MCPEPSHAGAAESEGTESEPTPLLRPAGGIPDLCVTVGEIAAAAELLDRGRGPFAVDAER
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEHHH
ASGFRYSGRAYLIQIRRAEAGTVLIDPVSHGGDPLTVLAPVAEVLSTNEWILHSADQDLP
CCCCEECCCEEEEEEEECCCCEEEECCCCCCCCCHHHHHHHHHHHCCCCEEEECCCCCCC
CLAEVGMRPPALYDTELAGRLAGFDRVNLAAMVERLLGLGLTKGHGAADWSKRPLPSAWL
HHHHCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHH
NYAALDVELLIELRAAISRVLAEQGKTDWAAQEFEHLRSFESRPPPAAARQDRWRRTSGI
HHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCH
HKVHDRRGLAAVRELWTARDRIAQRRDIAPRRILPDSAIIDAAIADPKSVDDLVALPVFG
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCCCCEEEECCCC
GRNQRRSAAVWWAALAAARESPDPPEIAEPANGPPPPGRWVRRKPAAAARLDAARAALTE
CCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHCCCCHHHHHHHHHHHHHHH
VSQRVRVPTENLVSPDLVRRLCWEWEDISQSSPDPIAAVEAYLRTGQARAWQLELVVPIL
HHHHHCCCHHHCCCHHHHHHHHHCHHHHCCCCCCHHHHHHHHHHCCCCCEEEEEHHHHHH
TAALTGAPDAGAQGDDGS
HHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3041371; 9097040; 9278503; 8107670 [H]