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The map label for this gene is secD

Identifier: 148823782

GI number: 148823782

Start: 2927332

End: 2929053

Strand: Reverse

Name: secD

Synonym: TBFG_12607

Alternate gene names: 148823782

Gene position: 2929053-2927332 (Counterclockwise)

Preceding gene: 148823783

Following gene: 148823781

Centisome position: 66.2

GC content: 66.2

Gene sequence:

>1722_bases
GTGGCATCGTCTTCGGCGCCGGTGCACCCTGCCCGTTACCTGTCGGTGTTCCTGGTGATGCTGATCGGCATCTATTTGCT
GGTGTTTTTCACCGGGGACAAGCACACCGCCCCCAAACTCGGCATTGACCTGCAGGGCGGCACCAGGGTCACGCTGACCG
CGCGCACACCGGACGGCTCGGCCCCGAGCCGGGAAGCGCTGGCACAGGCGCAGCAAATCATCAGCGCGCGGGTCAACGGG
CTGGGAGTGTCCGGGTCGGAGGTGGTCGTCGACGGTGACAACCTGGTCATCACGGTGCCCGGCAACGACGGCAGCGAGGC
ACGCAACCTCGGACAGACCGCTCGGCTGTACATCCGGCCGGTGCTCAACTCGATGCCGGCGCAGCCCGCAGCCGAAGAAC
CGCAGCCGGCACCCAGCGCCGAACCGCAGCCGCCCGGTCAACCCGCCGCACCGCCGCCAGCCCAATCGGGGGCGCCGGCT
TCACCGCAACCTGGGGCCCAACCGCGGCCCTATCCGCAGGACCCGGCGCCATCGCCCAACCCGACCTCACCGGCCAGCCC
GCCGCCGGCGCCGCCCGCTGAGGCGCCGGCCACGGATCCGCGCAAGGATCTCGCCGAGCGCATCGCCCAGGAGAAGAAGC
TGCGGCAGAGCACCAACCAATACATGCAGATGGTTGCACTGCAATTCCAGGCGACCCGCTGCGAGAGCGACGACATTTTG
GCCGGCAACGACGACCCGAAACTGCCGTTGGTGACCTGCTCGACCGACCACAAGACCGCGTACCTGCTGGCGCCGTCGAT
CATCAGCGGCGACCAGATCCAAAACGCCACCTCGGGTATGGACCAGCGCGGCATCGGCTACGTCGTCGACCTGCAGTTCA
AGGGTCCGGCGGCCAACATCTGGGCCGACTACACCGCCGCCCATATCGGCACCCAGACGGCGTTCACCCTGGACTCGCAG
GTTGTCAGTGCACCGCAGATCCAGGAAGCGATCCCCGGCGGCCGAACCCAGATCAGCGGTGGGGATCCGCCATTCACCGC
GGCGACCGCACGCCAGCTCGCCAACGTCCTCAAGTACGGGTCGCTGCCGCTGTCCTTCGAACCGTCGGAAGCCCAAACGG
TTTCGGCGACCTTGGGGTTGTCATCGCTGCGCGCGGGCATGATCGCGGGTGCGATCGGCCTGCTGTTGGTGCTGGTGTAT
TCGCTGCTCTACTACCGAGTGCTGGGACTGCTCACGGCCTTGTCGCTAGTGGCTTCTGGCTCAATGGTTTTTGCGATCCT
GGTGCTCTTGGGCCGATATATCAACTACACCCTAGATCTGGCTGGTATTGCGGGCCTGATCATCGGTATCGGGACCACCG
CCGACTCGTTCGTGGTGTTCTTCGAACGCATCAAAGACGAGATCCGCGAAGGCCGTTCGTTCCGGTCGGCAGTGCCGCGC
GGTTGGGCGCGTGCCCGCAAGACGATCGTGTCGGGCAACGCCGTCACTTTCCTGGCCGCTGCCGTGCTGTACTTTCTGGC
GATCGGTCAGGTGAAGGGGTTCGCGTTCACCCTGGGCCTCACCACGATCCTGGACCTCGTCGTGGTGTTCTTGGTGACGT
GGCCGTTGGTGTATCTGGCGTCCAAATCGTCGCTGCTGGCCAAGCCGGCATACAACGGCCTGGGAGCGGTGCAGCAGGTC
GCACGCGAACGCCGGGCCATGGCTCGGACGGGACGGGGATAG

Upstream 100 bases:

>100_bases
GGCCGACCGGAACCGACGAGCCGCTTGCGCGACGCGCCCCGGCGCGACACGTAGGCTCTGTCGGGGGTAGAAAACTGATT
CTCGAGGAGATACAAGGAAC

Downstream 100 bases:

>100_bases
CCGATGGCGTCGAAAGCAAAGACCGGCCGCGACGACGAAGCCACGTCGGCGGTCGAACTCACCGAGGCCACCGAGAGTGC
TGTGGCGCGGACCGACGGCG

Product: preprotein translocase subunit SecD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 573; Mature: 572

Protein sequence:

>573_residues
MASSSAPVHPARYLSVFLVMLIGIYLLVFFTGDKHTAPKLGIDLQGGTRVTLTARTPDGSAPSREALAQAQQIISARVNG
LGVSGSEVVVDGDNLVITVPGNDGSEARNLGQTARLYIRPVLNSMPAQPAAEEPQPAPSAEPQPPGQPAAPPPAQSGAPA
SPQPGAQPRPYPQDPAPSPNPTSPASPPPAPPAEAPATDPRKDLAERIAQEKKLRQSTNQYMQMVALQFQATRCESDDIL
AGNDDPKLPLVTCSTDHKTAYLLAPSIISGDQIQNATSGMDQRGIGYVVDLQFKGPAANIWADYTAAHIGTQTAFTLDSQ
VVSAPQIQEAIPGGRTQISGGDPPFTAATARQLANVLKYGSLPLSFEPSEAQTVSATLGLSSLRAGMIAGAIGLLLVLVY
SLLYYRVLGLLTALSLVASGSMVFAILVLLGRYINYTLDLAGIAGLIIGIGTTADSFVVFFERIKDEIREGRSFRSAVPR
GWARARKTIVSGNAVTFLAAAVLYFLAIGQVKGFAFTLGLTTILDLVVVFLVTWPLVYLASKSSLLAKPAYNGLGAVQQV
ARERRAMARTGRG

Sequences:

>Translated_573_residues
MASSSAPVHPARYLSVFLVMLIGIYLLVFFTGDKHTAPKLGIDLQGGTRVTLTARTPDGSAPSREALAQAQQIISARVNG
LGVSGSEVVVDGDNLVITVPGNDGSEARNLGQTARLYIRPVLNSMPAQPAAEEPQPAPSAEPQPPGQPAAPPPAQSGAPA
SPQPGAQPRPYPQDPAPSPNPTSPASPPPAPPAEAPATDPRKDLAERIAQEKKLRQSTNQYMQMVALQFQATRCESDDIL
AGNDDPKLPLVTCSTDHKTAYLLAPSIISGDQIQNATSGMDQRGIGYVVDLQFKGPAANIWADYTAAHIGTQTAFTLDSQ
VVSAPQIQEAIPGGRTQISGGDPPFTAATARQLANVLKYGSLPLSFEPSEAQTVSATLGLSSLRAGMIAGAIGLLLVLVY
SLLYYRVLGLLTALSLVASGSMVFAILVLLGRYINYTLDLAGIAGLIIGIGTTADSFVVFFERIKDEIREGRSFRSAVPR
GWARARKTIVSGNAVTFLAAAVLYFLAIGQVKGFAFTLGLTTILDLVVVFLVTWPLVYLASKSSLLAKPAYNGLGAVQQV
ARERRAMARTGRG
>Mature_572_residues
ASSSAPVHPARYLSVFLVMLIGIYLLVFFTGDKHTAPKLGIDLQGGTRVTLTARTPDGSAPSREALAQAQQIISARVNGL
GVSGSEVVVDGDNLVITVPGNDGSEARNLGQTARLYIRPVLNSMPAQPAAEEPQPAPSAEPQPPGQPAAPPPAQSGAPAS
PQPGAQPRPYPQDPAPSPNPTSPASPPPAPPAEAPATDPRKDLAERIAQEKKLRQSTNQYMQMVALQFQATRCESDDILA
GNDDPKLPLVTCSTDHKTAYLLAPSIISGDQIQNATSGMDQRGIGYVVDLQFKGPAANIWADYTAAHIGTQTAFTLDSQV
VSAPQIQEAIPGGRTQISGGDPPFTAATARQLANVLKYGSLPLSFEPSEAQTVSATLGLSSLRAGMIAGAIGLLLVLVYS
LLYYRVLGLLTALSLVASGSMVFAILVLLGRYINYTLDLAGIAGLIIGIGTTADSFVVFFERIKDEIREGRSFRSAVPRG
WARARKTIVSGNAVTFLAAAVLYFLAIGQVKGFAFTLGLTTILDLVVVFLVTWPLVYLASKSSLLAKPAYNGLGAVQQVA
RERRAMARTGRG

Specific function: Involved in protein export

COG id: COG0342

COG function: function code U; Preprotein translocase subunit SecD

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the secD/secF family. SecD subfamily

Homologues:

Organism=Escherichia coli, GI1786609, Length=276, Percent_Identity=27.536231884058, Blast_Score=113, Evalue=3e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SECD_MYCTU (Q50634)

Other databases:

- EMBL:   BX842580
- EMBL:   AE000516
- PIR:   B70726
- RefSeq:   NP_217103.1
- RefSeq:   NP_337163.2
- ProteinModelPortal:   Q50634
- EnsemblBacteria:   EBMYCT00000000015
- EnsemblBacteria:   EBMYCT00000069317
- GeneID:   888192
- GeneID:   925648
- GenomeReviews:   AE000516_GR
- GenomeReviews:   AL123456_GR
- KEGG:   mtc:MT2664
- KEGG:   mtu:Rv2587c
- TIGR:   MT2664
- TubercuList:   Rv2587c
- GeneTree:   EBGT00050000014864
- HOGENOM:   HBG302175
- OMA:   RDEIREG
- ProtClustDB:   PRK05812
- GO:   GO:0005829
- InterPro:   IPR005791
- InterPro:   IPR022813
- InterPro:   IPR022646
- InterPro:   IPR022645
- TIGRFAMs:   TIGR00916
- TIGRFAMs:   TIGR01129

Pfam domain/function: PF07549 Sec_GG; PF02355 SecD_SecF

EC number: NA

Molecular weight: Translated: 60268; Mature: 60137

Theoretical pI: Translated: 9.06; Mature: 9.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1ae13f34)-; HASH(0x18301378)-; HASH(0x1c0fa438)-; HASH(0x1c537040)-; HASH(0x1bc901d8)-; HASH(0x1c321590)-;

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASSSAPVHPARYLSVFLVMLIGIYLLVFFTGDKHTAPKLGIDLQGGTRVTLTARTPDGS
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEECCCCEEEEEEECCCCC
APSREALAQAQQIISARVNGLGVSGSEVVVDGDNLVITVPGNDGSEARNLGQTARLYIRP
CCHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCEEEEECCCCCHHHHHCCHHHHHHHHH
VLNSMPAQPAAEEPQPAPSAEPQPPGQPAAPPPAQSGAPASPQPGAQPRPYPQDPAPSPN
HHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
PTSPASPPPAPPAEAPATDPRKDLAERIAQEKKLRQSTNQYMQMVALQFQATRCESDDIL
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEE
AGNDDPKLPLVTCSTDHKTAYLLAPSIISGDQIQNATSGMDQRGIGYVVDLQFKGPAANI
ECCCCCCCEEEEECCCCCEEEEECCCHHCCHHHHHHHCCCCCCCCEEEEEEEECCCCCHH
WADYTAAHIGTQTAFTLDSQVVSAPQIQEAIPGGRTQISGGDPPFTAATARQLANVLKYG
HHHHHHHHHCCCCEEEECHHHHCCCHHHHHCCCCCEECCCCCCCCHHHHHHHHHHHHHHC
SLPLSFEPSEAQTVSATLGLSSLRAGMIAGAIGLLLVLVYSLLYYRVLGLLTALSLVASG
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
SMVFAILVLLGRYINYTLDLAGIAGLIIGIGTTADSFVVFFERIKDEIREGRSFRSAVPR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCHHHHHHCCH
GWARARKTIVSGNAVTFLAAAVLYFLAIGQVKGFAFTLGLTTILDLVVVFLVTWPLVYLA
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SKSSLLAKPAYNGLGAVQQVARERRAMARTGRG
CCCHHHCCCCCCHHHHHHHHHHHHHHHHHCCCH
>Mature Secondary Structure 
ASSSAPVHPARYLSVFLVMLIGIYLLVFFTGDKHTAPKLGIDLQGGTRVTLTARTPDGS
CCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEECCCCEEEEEEECCCCC
APSREALAQAQQIISARVNGLGVSGSEVVVDGDNLVITVPGNDGSEARNLGQTARLYIRP
CCHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCEEEEECCCCCHHHHHCCHHHHHHHHH
VLNSMPAQPAAEEPQPAPSAEPQPPGQPAAPPPAQSGAPASPQPGAQPRPYPQDPAPSPN
HHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
PTSPASPPPAPPAEAPATDPRKDLAERIAQEKKLRQSTNQYMQMVALQFQATRCESDDIL
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEE
AGNDDPKLPLVTCSTDHKTAYLLAPSIISGDQIQNATSGMDQRGIGYVVDLQFKGPAANI
ECCCCCCCEEEEECCCCCEEEEECCCHHCCHHHHHHHCCCCCCCCEEEEEEEECCCCCHH
WADYTAAHIGTQTAFTLDSQVVSAPQIQEAIPGGRTQISGGDPPFTAATARQLANVLKYG
HHHHHHHHHCCCCEEEECHHHHCCCHHHHHCCCCCEECCCCCCCCHHHHHHHHHHHHHHC
SLPLSFEPSEAQTVSATLGLSSLRAGMIAGAIGLLLVLVYSLLYYRVLGLLTALSLVASG
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
SMVFAILVLLGRYINYTLDLAGIAGLIIGIGTTADSFVVFFERIKDEIREGRSFRSAVPR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCHHHHHHCCH
GWARARKTIVSGNAVTFLAAAVLYFLAIGQVKGFAFTLGLTTILDLVVVFLVTWPLVYLA
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SKSSLLAKPAYNGLGAVQQVARERRAMARTGRG
CCCHHHCCCCCCHHHHHHHHHHHHHHHHHCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036